Drosophila melanogaster

0 known processes

Spt-I (Dmel_CG4016)

Serine palmitoyltransferase subunit I

(Aliases: Dmel\CG4016,SPT-I,lcb1,l(2)SH2 1626,Spt1,l(2)SH1626,CG4016)

Spt-I biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular protein modification process GO:0006464 438 0.230
transmembrane transport GO:0055085 139 0.145
organic substance transport GO:0071702 257 0.145
protein modification process GO:0036211 438 0.119
death GO:0016265 284 0.093
endocytosis GO:0006897 310 0.089
carbohydrate derivative biosynthetic process GO:1901137 85 0.079
ion transport GO:0006811 145 0.075
amino sugar metabolic process GO:0006040 10 0.074
establishment of localization in cell GO:0051649 402 0.060
vesicle mediated transport GO:0016192 381 0.059
lateral inhibition GO:0046331 206 0.057
carbohydrate derivative metabolic process GO:1901135 217 0.047
cellular protein localization GO:0034613 160 0.045
regulation of notch signaling pathway GO:0008593 100 0.045
epithelial cell differentiation GO:0030855 322 0.045
membrane lipid metabolic process GO:0006643 22 0.045
pigmentation GO:0043473 75 0.044
protein transport GO:0015031 155 0.043
programmed cell death GO:0012501 257 0.042
cell death GO:0008219 279 0.042
establishment of protein localization GO:0045184 163 0.042
protein localization GO:0008104 284 0.041
regulation of cell death GO:0010941 173 0.041
single organism intracellular transport GO:1902582 207 0.039
single organism behavior GO:0044708 391 0.038
cellular macromolecule localization GO:0070727 220 0.038
cellular lipid metabolic process GO:0044255 83 0.037
small molecule metabolic process GO:0044281 305 0.036
developmental pigmentation GO:0048066 68 0.036
proteolysis GO:0006508 192 0.035
organonitrogen compound metabolic process GO:1901564 318 0.035
cell motility GO:0048870 251 0.035
carbohydrate metabolic process GO:0005975 82 0.035
retina development in camera type eye GO:0060041 4 0.034
lipid biosynthetic process GO:0008610 46 0.033
phagocytosis GO:0006909 215 0.033
oxoacid metabolic process GO:0043436 103 0.033
camera type eye development GO:0043010 4 0.033
anion transport GO:0006820 41 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.031
protein prenylation GO:0018342 3 0.030
purine ribonucleotide catabolic process GO:0009154 109 0.030
single organism biosynthetic process GO:0044711 206 0.030
regulation of apoptotic process GO:0042981 130 0.030
neuromuscular junction development GO:0007528 149 0.030
ion transmembrane transport GO:0034220 122 0.029
organelle fusion GO:0048284 46 0.028
ribonucleoside metabolic process GO:0009119 127 0.028
immune system process GO:0002376 347 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
catabolic process GO:0009056 409 0.027
cellular ketone metabolic process GO:0042180 24 0.027
peptidyl amino acid modification GO:0018193 105 0.027
positive regulation of cell communication GO:0010647 250 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
defense response to other organism GO:0098542 225 0.026
response to biotic stimulus GO:0009607 294 0.025
amino acid transport GO:0006865 12 0.025
skeletal muscle fiber development GO:0048741 3 0.025
cellular ion homeostasis GO:0006873 39 0.024
autophagy GO:0006914 108 0.024
organonitrogen compound biosynthetic process GO:1901566 117 0.024
intracellular protein transport GO:0006886 104 0.024
response to external biotic stimulus GO:0043207 293 0.024
single organism carbohydrate metabolic process GO:0044723 72 0.023
cation homeostasis GO:0055080 51 0.023
cytoplasmic transport GO:0016482 130 0.022
single organism membrane fusion GO:0044801 42 0.022
glycoprotein biosynthetic process GO:0009101 41 0.022
lipid metabolic process GO:0006629 121 0.022
secondary metabolic process GO:0019748 75 0.022
neurological system process GO:0050877 358 0.022
organic acid metabolic process GO:0006082 103 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
glycoprotein metabolic process GO:0009100 41 0.021
toxin metabolic process GO:0009404 2 0.021
cellular cation homeostasis GO:0030003 38 0.021
single organism catabolic process GO:0044712 228 0.021
purine containing compound transmembrane transport GO:0072530 5 0.021
positive regulation of signal transduction GO:0009967 223 0.020
cation transport GO:0006812 110 0.020
growth GO:0040007 359 0.020
anion transmembrane transport GO:0098656 26 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
nephron development GO:0072006 3 0.019
cell division GO:0051301 248 0.019
cell migration GO:0016477 238 0.019
protein localization to organelle GO:0033365 82 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
regulation of cell size GO:0008361 63 0.019
eye development GO:0001654 323 0.019
eye pigment biosynthetic process GO:0006726 32 0.019
taxis GO:0042330 304 0.019
response to lipopolysaccharide GO:0032496 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
cellular pigmentation GO:0033059 12 0.019
cellular chemical homeostasis GO:0055082 40 0.018
organic substance catabolic process GO:1901575 308 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
multicellular organismal aging GO:0010259 140 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
membrane organization GO:0061024 112 0.018
synapse organization GO:0050808 196 0.018
positive regulation of signaling GO:0023056 243 0.018
myotube cell development GO:0014904 3 0.018
membrane fusion GO:0061025 42 0.018
single organism membrane organization GO:0044802 93 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
regulation of catabolic process GO:0009894 170 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
response to bacterium GO:0009617 198 0.018
notch signaling pathway GO:0007219 120 0.018
chemotaxis GO:0006935 249 0.018
localization of cell GO:0051674 257 0.018
body morphogenesis GO:0010171 2 0.017
regulation of catalytic activity GO:0050790 185 0.017
protein maturation GO:0051604 71 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
intracellular transport GO:0046907 228 0.017
inorganic ion transmembrane transport GO:0098660 73 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
apoptotic process GO:0006915 159 0.017
endomembrane system organization GO:0010256 119 0.017
outflow tract morphogenesis GO:0003151 4 0.017
regionalization GO:0003002 416 0.016
single organism cellular localization GO:1902580 180 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
nitrogen compound transport GO:0071705 85 0.016
divalent inorganic cation homeostasis GO:0072507 29 0.016
forebrain development GO:0030900 2 0.016
organophosphate metabolic process GO:0019637 195 0.016
negative regulation of calcium ion import GO:0090281 2 0.016
secretion GO:0046903 109 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
protein palmitoylation GO:0018345 2 0.016
regulation of programmed cell death GO:0043067 152 0.015
negative regulation of nervous system development GO:0051961 92 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
cellular catabolic process GO:0044248 372 0.015
aromatic compound catabolic process GO:0019439 166 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
compound eye development GO:0048749 307 0.015
response to other organism GO:0051707 293 0.015
steroid catabolic process GO:0006706 1 0.015
defense response GO:0006952 300 0.015
phosphorylation GO:0016310 294 0.015
carboxylic acid transport GO:0046942 18 0.014
regulation of localization GO:0032879 275 0.014
cellular homeostasis GO:0019725 80 0.014
pigment metabolic process GO:0042440 84 0.014
purine containing compound catabolic process GO:0072523 112 0.014
hippo signaling GO:0035329 20 0.014
regulation of hydrolase activity GO:0051336 97 0.014
pigment granule organization GO:0048753 12 0.014
metal ion transport GO:0030001 74 0.014
regulation of anatomical structure size GO:0090066 163 0.013
cortical cytoskeleton organization GO:0030865 29 0.013
kidney development GO:0001822 3 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
regulation of intracellular signal transduction GO:1902531 236 0.013
anterograde synaptic vesicle transport GO:0048490 3 0.013
response to pain GO:0048265 3 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
regulation of meiosis GO:0040020 3 0.013
positive regulation of cell motility GO:2000147 3 0.013
metal ion homeostasis GO:0055065 44 0.013
golgi organization GO:0007030 66 0.013
epithelial cell development GO:0002064 274 0.013
neuron death GO:0070997 27 0.013
protein catabolic process GO:0030163 101 0.013
ribosomal large subunit biogenesis GO:0042273 1 0.013
organic acid transport GO:0015849 18 0.013
regulation of neuron death GO:1901214 26 0.013
positive regulation of molecular function GO:0044093 136 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.012
leg disc morphogenesis GO:0007478 80 0.012
protein acylation GO:0043543 42 0.012
nucleoside catabolic process GO:0009164 112 0.012
biological adhesion GO:0022610 138 0.012
defense response to bacterium GO:0042742 178 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
cellular divalent inorganic cation homeostasis GO:0072503 23 0.012
regulation of cellular component size GO:0032535 98 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
heterocycle catabolic process GO:0046700 166 0.012
purine containing compound metabolic process GO:0072521 155 0.012
macromolecule glycosylation GO:0043413 32 0.012
regulation of growth GO:0040008 233 0.012
xenobiotic catabolic process GO:0042178 1 0.012
telencephalon development GO:0021537 2 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
regulation of transport GO:0051049 181 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
positive regulation of cell death GO:0010942 69 0.012
pigment cell differentiation GO:0050931 3 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.011
appendage morphogenesis GO:0035107 397 0.011
actin filament based process GO:0030029 220 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
leg disc development GO:0035218 92 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
liposaccharide metabolic process GO:1903509 8 0.011
actin cytoskeleton organization GO:0030036 206 0.011
eye pigment granule organization GO:0008057 12 0.011
embryonic morphogenesis GO:0048598 206 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
organophosphate catabolic process GO:0046434 112 0.011
protein processing GO:0016485 68 0.011
nucleotide catabolic process GO:0009166 109 0.011
digestive tract morphogenesis GO:0048546 127 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
protein glycosylation GO:0006486 32 0.011
monocarboxylic acid transport GO:0015718 3 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
ocellus pigment metabolic process GO:0046158 19 0.011
organelle membrane fusion GO:0090174 16 0.011
synapse assembly GO:0007416 143 0.011
branched chain amino acid transport GO:0015803 3 0.011
response to organophosphorus GO:0046683 2 0.011
organelle fission GO:0048285 340 0.010
regulation of cellular localization GO:0060341 136 0.010
developmental growth GO:0048589 280 0.010
cellular response to dna damage stimulus GO:0006974 223 0.010
intracellular signal transduction GO:0035556 300 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
mitotic nuclear division GO:0007067 213 0.010
sensory organ morphogenesis GO:0090596 260 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
divalent inorganic cation transport GO:0072511 30 0.010
digestive tract development GO:0048565 149 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
regulation of synapse structure and activity GO:0050803 128 0.010

Spt-I disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
sensory system disease DOID:0050155 0 0.026
nervous system disease DOID:863 0 0.026
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
renal tubular transport disease DOID:447 0 0.013
kidney disease DOID:557 0 0.013
urinary system disease DOID:18 0 0.013