Drosophila melanogaster

157 known processes

grh (Dmel_CG42311)

grainy head

(Aliases: Ntf1,EG:191D12.1,CG42311,Dmel_CG5058,Grh,l(2)06850,CG5058,Dmel_CG30111,NTF,hsk,BcDNA:LD38807,Ntf,NTF1,Elf-1/NTF-1,elf1(CAG)[[7]],NTF-1/Elf-1,Elf1,DREB,GRH,ntf-1,CG30111,Dmel\CG42311,l(2)s2140,Elf-1,elf1,NTF-1,l(2)IM45,Gh)

grh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
open tracheal system development GO:0007424 204 0.986
regulation of tube architecture open tracheal system GO:0035152 68 0.969
cuticle development GO:0042335 86 0.919
regulation of tube size open tracheal system GO:0035151 43 0.918
wing disc morphogenesis GO:0007472 344 0.880
branching involved in open tracheal system development GO:0060446 45 0.862
imaginal disc derived appendage development GO:0048737 399 0.840
imaginal disc derived wing hair organization GO:0035317 45 0.789
appendage morphogenesis GO:0035107 397 0.772
imaginal disc derived wing morphogenesis GO:0007476 337 0.738
respiratory system development GO:0060541 213 0.737
regulation of tube length open tracheal system GO:0035159 24 0.718
embryonic development via the syncytial blastoderm GO:0001700 148 0.690
negative regulation of gene expression GO:0010629 387 0.687
imaginal disc derived appendage morphogenesis GO:0035114 395 0.663
chitin based cuticle development GO:0040003 49 0.638
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.632
appendage development GO:0048736 401 0.625
negative regulation of transcription dna templated GO:0045892 237 0.614
blastoderm segmentation GO:0007350 159 0.598
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.593
post embryonic appendage morphogenesis GO:0035120 385 0.551
growth GO:0040007 359 0.530
regulation of multicellular organismal development GO:2000026 414 0.529
segmentation GO:0035282 207 0.517
torso signaling pathway GO:0008293 21 0.501
embryo development ending in birth or egg hatching GO:0009792 152 0.486
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.483
negative regulation of biosynthetic process GO:0009890 277 0.388
negative regulation of nucleic acid templated transcription GO:1903507 240 0.374
non sensory hair organization GO:0035316 47 0.363
regulation of anatomical structure size GO:0090066 163 0.342
developmental growth GO:0048589 280 0.339
transcription from rna polymerase ii promoter GO:0006366 368 0.334
epithelial tube morphogenesis GO:0060562 88 0.329
regulation of tube diameter open tracheal system GO:0035158 11 0.303
regionalization GO:0003002 416 0.279
regulation of cell morphogenesis GO:0022604 163 0.278
renal system development GO:0072001 72 0.277
regulation of cell differentiation GO:0045595 302 0.265
proteolysis GO:0006508 192 0.235
spiracle morphogenesis open tracheal system GO:0035277 22 0.234
establishment of body hair or bristle planar orientation GO:0048104 6 0.223
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.219
epithelial cell migration open tracheal system GO:0007427 32 0.214
negative regulation of cellular metabolic process GO:0031324 382 0.213
specification of organ identity GO:0010092 3 0.206
morphogenesis of a branching epithelium GO:0061138 45 0.200
cell death GO:0008219 279 0.198
photoreceptor cell development GO:0042461 96 0.191
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.191
trachea morphogenesis GO:0060439 22 0.188
primary amino compound biosynthetic process GO:1901162 2 0.184
branching morphogenesis of an epithelial tube GO:0048754 45 0.184
tripartite regional subdivision GO:0007351 103 0.164
establishment of tissue polarity GO:0007164 87 0.161
positive regulation of nucleic acid templated transcription GO:1903508 266 0.160
imaginal disc derived wing vein specification GO:0007474 48 0.158
negative regulation of cellular biosynthetic process GO:0031327 277 0.157
chitin based cuticle sclerotization GO:0007593 19 0.154
trachea development GO:0060438 29 0.153
hindgut development GO:0061525 58 0.151
negative regulation of rna metabolic process GO:0051253 251 0.147
anterior posterior pattern specification GO:0009952 136 0.142
positive regulation of transcription dna templated GO:0045893 266 0.136
regulation of organ formation GO:0003156 3 0.128
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.127
cell division GO:0051301 248 0.126
urogenital system development GO:0001655 72 0.126
columnar cuboidal epithelial cell development GO:0002066 249 0.124
dorsal trunk growth open tracheal system GO:0035001 7 0.124
chromosome segregation GO:0007059 157 0.124
response to biotic stimulus GO:0009607 294 0.113
regulation of developmental growth GO:0048638 174 0.110
organonitrogen compound biosynthetic process GO:1901566 117 0.108
compound eye morphogenesis GO:0001745 249 0.105
regulation of defense response GO:0031347 102 0.102
epithelial cell differentiation GO:0030855 322 0.101
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.101
response to external biotic stimulus GO:0043207 293 0.101
sensory organ morphogenesis GO:0090596 260 0.101
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.099
negative regulation of cell cycle process GO:0010948 109 0.099
determination of digestive tract left right asymmetry GO:0071907 6 0.098
regulation of cell cycle process GO:0010564 181 0.098
cell recognition GO:0008037 102 0.098
axis specification GO:0009798 167 0.098
establishment of planar polarity GO:0001736 87 0.098
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.097
regulation of imaginal disc derived wing size GO:0044719 20 0.094
posttranscriptional regulation of gene expression GO:0010608 145 0.090
digestive system development GO:0055123 149 0.090
meiotic cell cycle process GO:1903046 132 0.085
regulation of mitosis GO:0007088 56 0.085
developmental growth involved in morphogenesis GO:0060560 65 0.084
negative regulation of developmental growth GO:0048640 64 0.084
enzyme linked receptor protein signaling pathway GO:0007167 179 0.083
tissue morphogenesis GO:0048729 297 0.081
malpighian tubule development GO:0072002 64 0.081
positive regulation of macromolecule metabolic process GO:0010604 405 0.080
response to wounding GO:0009611 94 0.078
gene silencing GO:0016458 138 0.075
myotube cell development GO:0014904 3 0.074
regulation of tube size GO:0035150 46 0.074
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.073
cellular response to organic cyclic compound GO:0071407 32 0.073
pericardial nephrocyte differentiation GO:0061320 9 0.071
negative regulation of rna biosynthetic process GO:1902679 240 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.070
response to other organism GO:0051707 293 0.069
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.067
regulation of cell cycle GO:0051726 291 0.066
regulation of embryonic development GO:0045995 68 0.065
negative regulation of hormone biosynthetic process GO:0032353 1 0.064
establishment or maintenance of polarity of embryonic epithelium GO:0016332 3 0.064
regulation of organ morphogenesis GO:2000027 78 0.063
immune system process GO:0002376 347 0.063
negative regulation of cell cycle phase transition GO:1901988 103 0.060
regulation of tube diameter GO:0035296 14 0.060
cardiocyte differentiation GO:0035051 29 0.058
branch fusion open tracheal system GO:0035147 17 0.058
epidermis development GO:0008544 65 0.057
regulation of neuron projection development GO:0010975 69 0.056
negative regulation of gene expression epigenetic GO:0045814 77 0.055
limb development GO:0060173 1 0.055
cell fate specification GO:0001708 71 0.054
protein catabolic process GO:0030163 101 0.054
positive regulation of biosynthetic process GO:0009891 316 0.053
regulation of cell cycle phase transition GO:1901987 130 0.053
nephron epithelium morphogenesis GO:0072088 3 0.053
eggshell chorion assembly GO:0007306 66 0.051
germ cell migration GO:0008354 43 0.050
regulation of cellular protein metabolic process GO:0032268 243 0.049
epithelial cell type specification open tracheal system GO:0035153 11 0.049
dna metabolic process GO:0006259 227 0.049
anterior posterior axis specification GO:0009948 109 0.048
stem cell differentiation GO:0048863 117 0.047
positive regulation of rna biosynthetic process GO:1902680 266 0.046
chemotaxis GO:0006935 249 0.046
tracheal outgrowth open tracheal system GO:0007426 18 0.045
terminal region determination GO:0007362 25 0.045
regulation of protein metabolic process GO:0051246 256 0.044
embryonic axis specification GO:0000578 107 0.044
regulation of muscle organ development GO:0048634 13 0.044
enteroendocrine cell differentiation GO:0035883 1 0.043
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.043
imaginal disc derived wing hair site selection GO:0035320 4 0.043
response to organic cyclic compound GO:0014070 89 0.043
regulation of cell adhesion GO:0030155 27 0.042
oocyte construction GO:0007308 112 0.042
striated muscle cell differentiation GO:0051146 90 0.042
response to lipid GO:0033993 38 0.041
body morphogenesis GO:0010171 2 0.041
skin development GO:0043588 65 0.040
positive regulation of cell communication GO:0010647 250 0.039
segment polarity determination GO:0007367 25 0.039
regulation of cuticle pigmentation GO:0048079 16 0.038
developmental maturation GO:0021700 172 0.038
regulation of developmental pigmentation GO:0048070 24 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
leg disc development GO:0035218 92 0.037
protein maturation GO:0051604 71 0.037
skeletal muscle fiber development GO:0048741 3 0.037
protein modification process GO:0036211 438 0.037
polarized epithelial cell differentiation GO:0030859 10 0.036
humoral immune response GO:0006959 117 0.036
neuroblast development GO:0014019 13 0.036
tube fusion GO:0035146 17 0.036
axonal fasciculation GO:0007413 12 0.036
epithelial cell development GO:0002064 274 0.035
cardioblast differentiation GO:0010002 20 0.035
limb morphogenesis GO:0035108 1 0.035
amino sugar metabolic process GO:0006040 10 0.035
chromatin organization GO:0006325 207 0.033
molting cycle process GO:0022404 29 0.032
reproductive behavior GO:0019098 122 0.032
eye photoreceptor cell development GO:0042462 81 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
sterol homeostasis GO:0055092 4 0.031
defense response to other organism GO:0098542 225 0.031
developmental cell growth GO:0048588 52 0.031
hair cell differentiation GO:0035315 47 0.031
morphogenesis of a branching structure GO:0001763 45 0.031
compound eye photoreceptor development GO:0042051 78 0.031
renal filtration cell differentiation GO:0061318 12 0.031
regulation of chromosome organization GO:0033044 64 0.031
nephron development GO:0072006 3 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
dorsal closure GO:0007391 79 0.029
dendrite self avoidance GO:0070593 8 0.029
epithelial cell migration GO:0010631 148 0.029
response to sterol GO:0036314 34 0.029
neuron recognition GO:0008038 101 0.029
single organism biosynthetic process GO:0044711 206 0.029
chitin metabolic process GO:0006030 7 0.028
establishment of epithelial cell apical basal polarity GO:0045198 10 0.028
determination of dorsal ventral asymmetry GO:0048262 3 0.028
periodic partitioning GO:0007365 29 0.028
larval development GO:0002164 104 0.027
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.027
forebrain development GO:0030900 2 0.027
cell cycle g2 m phase transition GO:0044839 22 0.027
positive regulation of signal transduction GO:0009967 223 0.027
response to organic substance GO:0010033 284 0.026
axonogenesis GO:0007409 290 0.026
axon development GO:0061564 297 0.026
establishment of apical basal cell polarity GO:0035089 12 0.026
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.026
organonitrogen compound metabolic process GO:1901564 318 0.025
central nervous system development GO:0007417 201 0.025
regulation of protein modification process GO:0031399 112 0.025
negative regulation of cell cycle GO:0045786 116 0.025
neuron projection guidance GO:0097485 241 0.025
cuticle pattern formation GO:0035017 27 0.025
tube formation GO:0035148 21 0.025
epithelial tube formation GO:0072175 7 0.024
morphogenesis of an epithelium GO:0002009 276 0.024
cardiac muscle tissue development GO:0048738 9 0.024
muscle organ development GO:0007517 127 0.024
positive regulation of cell cell adhesion GO:0022409 9 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
morphogenesis of a polarized epithelium GO:0001738 93 0.024
dna replication GO:0006260 48 0.023
wound healing GO:0042060 75 0.023
equator specification GO:0045317 4 0.023
macromolecular complex assembly GO:0065003 256 0.023
head development GO:0060322 135 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
regulation of malpighian tubule diameter GO:0035297 3 0.022
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.021
axon choice point recognition GO:0016198 26 0.021
regulation of organelle organization GO:0033043 196 0.021
dephosphorylation GO:0016311 51 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
regulation of actin cytoskeleton organization GO:0032956 42 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
cuticle pigmentation GO:0048067 22 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.020
retina development in camera type eye GO:0060041 4 0.020
organ induction GO:0001759 3 0.020
protein ubiquitination GO:0016567 70 0.020
reproductive structure development GO:0048608 74 0.020
defense response to bacterium GO:0042742 178 0.019
positive regulation of innate immune response GO:0045089 38 0.019
tube development GO:0035295 244 0.019
cell cycle phase transition GO:0044770 140 0.019
digestive tract morphogenesis GO:0048546 127 0.019
muscle fiber development GO:0048747 12 0.019
connective tissue development GO:0061448 3 0.019
regulation of cell development GO:0060284 215 0.019
positive regulation of immune system process GO:0002684 68 0.019
digestive tract development GO:0048565 149 0.019
phenol containing compound metabolic process GO:0018958 57 0.019
muscle tissue morphogenesis GO:0060415 2 0.019
axis elongation GO:0003401 3 0.019
negative regulation of apoptotic process GO:0043066 63 0.019
amine metabolic process GO:0009308 12 0.019
cellular protein catabolic process GO:0044257 83 0.019
molting cycle GO:0042303 56 0.019
establishment of organelle localization GO:0051656 122 0.018
regulation of hydrolase activity GO:0051336 97 0.018
cellular response to organic substance GO:0071310 132 0.018
protein processing GO:0016485 68 0.018
mitotic cell cycle embryonic GO:0045448 38 0.018
response to bacterium GO:0009617 198 0.018
covalent chromatin modification GO:0016569 106 0.017
wnt signaling pathway GO:0016055 98 0.017
muscle tissue development GO:0060537 30 0.017
muscle structure development GO:0061061 224 0.017
renal tubule development GO:0061326 64 0.017
stem cell maintenance GO:0019827 67 0.017
actin polymerization or depolymerization GO:0008154 31 0.017
developmental programmed cell death GO:0010623 138 0.017
determination of ventral identity GO:0048264 1 0.017
embryonic pattern specification GO:0009880 174 0.017
kidney epithelium development GO:0072073 3 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
apoptotic process involved in development GO:1902742 20 0.016
regulation of multi organism process GO:0043900 131 0.016
peptidyl threonine phosphorylation GO:0018107 2 0.016
peptidyl threonine modification GO:0018210 3 0.016
response to ecdysone GO:0035075 34 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
regulation of wnt signaling pathway GO:0030111 68 0.016
embryonic hemopoiesis GO:0035162 26 0.016
imaginal disc eversion GO:0007561 4 0.016
cell projection assembly GO:0030031 94 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
cell proliferation GO:0008283 299 0.015
mitotic spindle organization GO:0007052 220 0.015
positive regulation of defense response GO:0031349 59 0.015
anatomical structure homeostasis GO:0060249 97 0.015
dorsal closure spreading of leading edge cells GO:0007395 4 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
regulation of cell division GO:0051302 72 0.015
convergent extension involved in gastrulation GO:0060027 2 0.015
gonad development GO:0008406 50 0.015
amino sugar biosynthetic process GO:0046349 5 0.015
muscle cell differentiation GO:0042692 103 0.015
epithelium migration GO:0090132 148 0.015
regulation of smoothened signaling pathway GO:0008589 28 0.015
antimicrobial humoral response GO:0019730 99 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
positive regulation of gene expression GO:0010628 290 0.014
adipose tissue development GO:0060612 2 0.014
antimicrobial peptide production GO:0002775 46 0.014
cellular protein modification process GO:0006464 438 0.014
ovarian follicle cell migration GO:0007297 121 0.014
erbb signaling pathway GO:0038127 58 0.014
heart field specification GO:0003128 0 0.014
regulation of cellular amide metabolic process GO:0034248 39 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
hatching GO:0035188 4 0.014
genitalia morphogenesis GO:0035112 16 0.014
death GO:0016265 284 0.014
reproductive system development GO:0061458 74 0.014
positive regulation of growth GO:0045927 75 0.014
chromatin silencing GO:0006342 76 0.014
g2 m transition of mitotic cell cycle GO:0000086 19 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
regulation of response to biotic stimulus GO:0002831 63 0.014
regulation of protein ubiquitination GO:0031396 22 0.014
establishment of localization in cell GO:0051649 402 0.014
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.013
hindgut morphogenesis GO:0007442 58 0.013
regulation of histone modification GO:0031056 20 0.013
negative regulation of signal transduction GO:0009968 206 0.013
protein complex biogenesis GO:0070271 201 0.013
negative regulation of dna endoreduplication GO:0032876 2 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
genitalia development GO:0048806 26 0.013
peptidyl amino acid modification GO:0018193 105 0.013
mesodermal cell fate determination GO:0007500 2 0.013
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.013
muscle cell fate specification GO:0042694 7 0.013
regulation of embryonic cell shape GO:0016476 30 0.013
chromosome organization GO:0051276 360 0.013
negative regulation of imaginal disc growth GO:0045571 8 0.013
regulation of establishment of planar polarity GO:0090175 22 0.013
genital disc sexually dimorphic development GO:0035263 4 0.013
negative regulation of smoothened signaling pathway GO:0045879 16 0.013
chromatin modification GO:0016568 147 0.013
regulation of dna binding GO:0051101 10 0.013
defense response to gram negative bacterium GO:0050829 94 0.012
wing and notum subfield formation GO:0035309 13 0.012
regulation of cell size GO:0008361 63 0.012
macromolecule catabolic process GO:0009057 161 0.012
lipid metabolic process GO:0006629 121 0.012
response to ketone GO:1901654 34 0.012
dna endoreduplication GO:0042023 22 0.012
regulation of response to external stimulus GO:0032101 115 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.012
regulation of neuron differentiation GO:0045664 103 0.012
organ growth GO:0035265 56 0.012
brain development GO:0007420 120 0.012
rhabdomere development GO:0042052 38 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
cellular ketone metabolic process GO:0042180 24 0.012
cardiac muscle cell differentiation GO:0055007 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.012
positive regulation of signaling GO:0023056 243 0.012
cellular amine metabolic process GO:0044106 12 0.012
epidermal cell differentiation GO:0009913 51 0.012
regulation of immune system process GO:0002682 176 0.012
labial disc development GO:0035217 4 0.012
mrna processing GO:0006397 104 0.012
spindle organization GO:0007051 253 0.011
formation of anatomical boundary GO:0048859 37 0.011
malpighian tubule bud morphogenesis GO:0061332 3 0.011
dorsal ventral axis specification GO:0009950 66 0.011
organic substance catabolic process GO:1901575 308 0.011
cell growth GO:0016049 108 0.011
cardiac cell fate commitment GO:0060911 17 0.011
meiotic nuclear division GO:0007126 151 0.011
regulation of cellular component movement GO:0051270 42 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
eye morphogenesis GO:0048592 260 0.011
glandular epithelial cell differentiation GO:0002067 1 0.011
regulation of nuclear division GO:0051783 58 0.011
dna dependent dna replication GO:0006261 17 0.011
regulation of growth GO:0040008 233 0.010
membrane invagination GO:0010324 11 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
imaginal disc derived leg segmentation GO:0036011 26 0.010
meiotic chromosome segregation GO:0045132 59 0.010
positive regulation of viral process GO:0048524 2 0.010
dendrite development GO:0016358 204 0.010
apoptotic process involved in morphogenesis GO:0060561 3 0.010
protein complex assembly GO:0006461 200 0.010
cellular response to ecdysone GO:0071390 17 0.010

grh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
congenital heart disease DOID:1682 0 0.012
tetralogy of fallot DOID:6419 0 0.012
heart disease DOID:114 0 0.012
disease of anatomical entity DOID:7 0 0.012
cardiovascular system disease DOID:1287 0 0.012