Drosophila melanogaster

38 known processes

prom (Dmel_CG42310)

prominin

(Aliases: eyc,CG42310,CG30165,CG30164,CG30166,CG4556,Dmel_CG30165,Dmel_CG30164,Dmel\CG42310,Dmel_CG30166)

prom biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye photoreceptor cell differentiation GO:0001754 145 0.356
rhabdomere development GO:0042052 38 0.286
cilium morphogenesis GO:0060271 39 0.274
sensory organ morphogenesis GO:0090596 260 0.266
positive regulation of biosynthetic process GO:0009891 316 0.193
eye photoreceptor cell development GO:0042462 81 0.175
compound eye photoreceptor development GO:0042051 78 0.134
eye morphogenesis GO:0048592 260 0.125
synapse assembly GO:0007416 143 0.123
neuron projection guidance GO:0097485 241 0.113
compound eye photoreceptor cell differentiation GO:0001751 140 0.110
positive regulation of rna biosynthetic process GO:1902680 266 0.100
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.092
photoreceptor cell development GO:0042461 96 0.089
post embryonic appendage morphogenesis GO:0035120 385 0.084
regulation of catabolic process GO:0009894 170 0.077
organic substance catabolic process GO:1901575 308 0.072
compound eye morphogenesis GO:0001745 249 0.071
establishment of localization in cell GO:0051649 402 0.070
photoreceptor cell differentiation GO:0046530 170 0.069
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.065
pigment metabolic process GO:0042440 84 0.064
cellular protein localization GO:0034613 160 0.061
transcription from rna polymerase ii promoter GO:0006366 368 0.060
synaptic transmission GO:0007268 288 0.060
regulation of multicellular organismal development GO:2000026 414 0.059
compound eye development GO:0048749 307 0.058
carboxylic acid metabolic process GO:0019752 92 0.057
regulation of synapse assembly GO:0051963 94 0.056
positive regulation of nucleic acid templated transcription GO:1903508 266 0.054
purine nucleoside metabolic process GO:0042278 127 0.051
neuromuscular junction development GO:0007528 149 0.051
axon guidance GO:0007411 233 0.050
body morphogenesis GO:0010171 2 0.050
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.049
ubiquitin dependent protein catabolic process GO:0006511 78 0.048
axonogenesis GO:0007409 290 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
carbohydrate derivative metabolic process GO:1901135 217 0.044
positive regulation of cellular biosynthetic process GO:0031328 316 0.044
regulation of molecular function GO:0065009 217 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
regulation of localization GO:0032879 275 0.041
rhodopsin metabolic process GO:0046154 10 0.040
macromolecular complex assembly GO:0065003 256 0.040
response to organophosphorus GO:0046683 2 0.040
protein modification process GO:0036211 438 0.040
wing disc morphogenesis GO:0007472 344 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
single organism biosynthetic process GO:0044711 206 0.040
positive regulation of cellular component organization GO:0051130 156 0.039
appendage development GO:0048736 401 0.039
proteolysis GO:0006508 192 0.039
ribonucleoside catabolic process GO:0042454 112 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
cellular catabolic process GO:0044248 372 0.039
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.037
positive regulation of gene expression GO:0010628 290 0.036
regulation of nervous system development GO:0051960 248 0.036
regulation of organelle organization GO:0033043 196 0.035
taxis GO:0042330 304 0.035
organic acid metabolic process GO:0006082 103 0.034
axon development GO:0061564 297 0.034
intracellular signal transduction GO:0035556 300 0.034
aromatic compound catabolic process GO:0019439 166 0.034
catabolic process GO:0009056 409 0.034
regulation of growth GO:0040008 233 0.033
sensory perception of chemical stimulus GO:0007606 116 0.033
regionalization GO:0003002 416 0.033
small molecule metabolic process GO:0044281 305 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.031
developmental growth GO:0048589 280 0.031
camera type eye morphogenesis GO:0048593 2 0.031
protein localization GO:0008104 284 0.030
response to abiotic stimulus GO:0009628 341 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
camera type eye development GO:0043010 4 0.030
multicellular organismal homeostasis GO:0048871 41 0.029
regulation of phosphate metabolic process GO:0019220 210 0.029
regulation of cell cycle GO:0051726 291 0.029
photoreceptor cell maintenance GO:0045494 11 0.029
positive regulation of transcription dna templated GO:0045893 266 0.028
single organism catabolic process GO:0044712 228 0.028
nucleoside phosphate catabolic process GO:1901292 110 0.028
regulation of cell development GO:0060284 215 0.028
programmed cell death GO:0012501 257 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
anatomical structure homeostasis GO:0060249 97 0.027
retina development in camera type eye GO:0060041 4 0.026
positive regulation of cell migration GO:0030335 2 0.026
cellular amine metabolic process GO:0044106 12 0.026
neurological system process GO:0050877 358 0.026
response to organic substance GO:0010033 284 0.026
positive regulation of signaling GO:0023056 243 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
rho protein signal transduction GO:0007266 14 0.025
regulation of proteolysis GO:0030162 87 0.024
imaginal disc derived wing vein specification GO:0007474 48 0.024
positive regulation of rho gtpase activity GO:0032321 19 0.024
protein complex biogenesis GO:0070271 201 0.024
regulation of cellular localization GO:0060341 136 0.024
positive regulation of cell communication GO:0010647 250 0.024
purine ribonucleoside catabolic process GO:0046130 112 0.024
purine nucleotide catabolic process GO:0006195 109 0.024
detection of chemical stimulus GO:0009593 93 0.024
cellular protein modification process GO:0006464 438 0.024
response to temperature stimulus GO:0009266 106 0.024
regulation of rho gtpase activity GO:0032319 20 0.024
fat soluble vitamin metabolic process GO:0006775 1 0.024
regulation of cell cycle process GO:0010564 181 0.023
vitamin biosynthetic process GO:0009110 1 0.023
regulation of catalytic activity GO:0050790 185 0.023
ras protein signal transduction GO:0007265 88 0.023
organophosphate catabolic process GO:0046434 112 0.023
developmental pigmentation GO:0048066 68 0.022
positive regulation of developmental process GO:0051094 143 0.022
locomotory behavior GO:0007626 176 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
phagocytosis GO:0006909 215 0.022
adult behavior GO:0030534 137 0.022
cellular macromolecule localization GO:0070727 220 0.022
regulation of synapse structure and activity GO:0050803 128 0.022
macromolecule catabolic process GO:0009057 161 0.021
ion transport GO:0006811 145 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of anatomical structure size GO:0090066 163 0.020
protein phosphorylation GO:0006468 169 0.020
eye antennal disc development GO:0035214 60 0.020
cell division GO:0051301 248 0.020
regulation of protein metabolic process GO:0051246 256 0.020
amine metabolic process GO:0009308 12 0.020
detection of stimulus GO:0051606 156 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
calcium ion transport GO:0006816 24 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
endomembrane system organization GO:0010256 119 0.019
endocytosis GO:0006897 310 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
synapse organization GO:0050808 196 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
regulation of programmed cell death GO:0043067 152 0.019
synaptic growth at neuromuscular junction GO:0051124 119 0.019
negative regulation of gene expression GO:0010629 387 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
divalent metal ion transport GO:0070838 26 0.019
mesenchymal cell differentiation GO:0048762 1 0.018
gtp catabolic process GO:0006184 72 0.018
cellular lipid metabolic process GO:0044255 83 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
male mating behavior GO:0060179 70 0.018
digestive system development GO:0055123 149 0.018
rhodopsin biosynthetic process GO:0016063 9 0.018
positive regulation of apoptotic process GO:0043065 47 0.018
behavioral response to ethanol GO:0048149 49 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
regulation of synapse organization GO:0050807 110 0.018
oxoacid metabolic process GO:0043436 103 0.017
response to endogenous stimulus GO:0009719 119 0.017
signal release GO:0023061 49 0.017
vesicle mediated transport GO:0016192 381 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
organic substance transport GO:0071702 257 0.017
response to fungus GO:0009620 50 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
salivary gland development GO:0007431 162 0.017
positive regulation of nucleotide catabolic process GO:0030813 46 0.017
kidney development GO:0001822 3 0.016
cellular response to organic substance GO:0071310 132 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
homeostatic process GO:0042592 199 0.016
regulation of cell projection organization GO:0031344 92 0.016
eye development GO:0001654 323 0.016
purine containing compound metabolic process GO:0072521 155 0.016
hindbrain development GO:0030902 2 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
purine containing compound catabolic process GO:0072523 112 0.016
response to oxygen containing compound GO:1901700 200 0.016
response to wounding GO:0009611 94 0.016
mitotic nuclear division GO:0007067 213 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
retina homeostasis GO:0001895 13 0.015
rhythmic process GO:0048511 106 0.015
regulation of response to stress GO:0080134 200 0.015
plasma membrane organization GO:0007009 26 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
cellular protein catabolic process GO:0044257 83 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
regulation of rho protein signal transduction GO:0035023 20 0.015
fat soluble vitamin biosynthetic process GO:0042362 1 0.015
positive regulation of cell motility GO:2000147 3 0.015
filopodium assembly GO:0046847 33 0.015
positive regulation of catabolic process GO:0009896 105 0.015
nucleoside metabolic process GO:0009116 127 0.015
tube development GO:0035295 244 0.015
cell death GO:0008219 279 0.015
multi multicellular organism process GO:0044706 123 0.015
neuron recognition GO:0008038 101 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
appendage morphogenesis GO:0035107 397 0.014
secondary metabolic process GO:0019748 75 0.014
positive regulation of molecular function GO:0044093 136 0.014
exocrine system development GO:0035272 162 0.014
chemotaxis GO:0006935 249 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
peptidyl amino acid modification GO:0018193 105 0.014
death GO:0016265 284 0.014
protein heterooligomerization GO:0051291 4 0.014
protein transport GO:0015031 155 0.014
response to glucose GO:0009749 2 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
defense response to other organism GO:0098542 225 0.014
cuticle development GO:0042335 86 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
heterocycle catabolic process GO:0046700 166 0.014
organelle localization GO:0051640 148 0.014
retina morphogenesis in camera type eye GO:0060042 2 0.014
mesenchymal cell development GO:0014031 1 0.014
positive regulation of phosphorylation GO:0042327 87 0.013
lateral inhibition GO:0046331 206 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
regulation of microtubule based process GO:0032886 49 0.013
positive regulation of gtp catabolic process GO:0033126 43 0.013
rac protein signal transduction GO:0016601 3 0.013
eye pigment metabolic process GO:0042441 33 0.013
response to external biotic stimulus GO:0043207 293 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
regulation of nucleotide catabolic process GO:0030811 48 0.013
notch signaling pathway GO:0007219 120 0.013
protein geranylgeranylation GO:0018344 3 0.013
organophosphate metabolic process GO:0019637 195 0.013
cellular response to external stimulus GO:0071496 66 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
protein catabolic process GO:0030163 101 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
regulation of apoptotic process GO:0042981 130 0.013
eye pigmentation GO:0048069 43 0.013
immune system process GO:0002376 347 0.013
gtp metabolic process GO:0046039 72 0.013
neurotransmitter transport GO:0006836 37 0.012
nucleotide metabolic process GO:0009117 161 0.012
positive regulation of synapse assembly GO:0051965 29 0.012
digestive tract development GO:0048565 149 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.012
immune response activating signal transduction GO:0002757 2 0.012
regulation of cell differentiation GO:0045595 302 0.012
limb development GO:0060173 1 0.012
forebrain development GO:0030900 2 0.012
circadian rhythm GO:0007623 105 0.012
muscle organ development GO:0007517 127 0.012
response to other organism GO:0051707 293 0.012
response to hexose GO:0009746 3 0.012
nucleoside catabolic process GO:0009164 112 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
cell recognition GO:0008037 102 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
gland development GO:0048732 191 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
tube morphogenesis GO:0035239 191 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
encapsulation of foreign target GO:0035010 38 0.012
positive regulation of gtpase activity GO:0043547 43 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
lipid metabolic process GO:0006629 121 0.012
regulation of intracellular signal transduction GO:1902531 236 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
single organism intracellular transport GO:1902582 207 0.011
protein processing GO:0016485 68 0.011
regulation of developmental growth GO:0048638 174 0.011
positive regulation of nervous system development GO:0051962 69 0.011
defense response to bacterium GO:0042742 178 0.011
regulation of cell death GO:0010941 173 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
protein transmembrane transport GO:0071806 4 0.011
cellular ketone metabolic process GO:0042180 24 0.011
protein complex assembly GO:0006461 200 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
response to monosaccharide GO:0034284 4 0.011
defense response GO:0006952 300 0.011
receptor clustering GO:0043113 3 0.011
regulation of neurogenesis GO:0050767 158 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
organelle fission GO:0048285 340 0.011
response to starvation GO:0042594 97 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
regulation of neuron differentiation GO:0045664 103 0.011
mrna metabolic process GO:0016071 124 0.011
salivary gland morphogenesis GO:0007435 145 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
organelle fusion GO:0048284 46 0.011
rna processing GO:0006396 147 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
gland morphogenesis GO:0022612 145 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
negative regulation of cell cycle GO:0045786 116 0.010
protein maturation GO:0051604 71 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
cellular response to oxidative stress GO:0034599 28 0.010
pigmentation GO:0043473 75 0.010
regulation of hydrolase activity GO:0051336 97 0.010
positive regulation of transport GO:0051050 92 0.010
regulation of behavior GO:0050795 75 0.010
kidney epithelium development GO:0072073 3 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
connective tissue development GO:0061448 3 0.010
divalent inorganic cation transport GO:0072511 30 0.010
malpighian tubule development GO:0072002 64 0.010
melanotic encapsulation of foreign target GO:0035011 30 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
cellular response to starvation GO:0009267 61 0.010

prom disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
sensory system disease DOID:0050155 0 0.017
nervous system disease DOID:863 0 0.017
eye and adnexa disease DOID:1492 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.011