Drosophila melanogaster

11 known processes

Ddx1 (Dmel_CG9054)

Dead-box-1

(Aliases: Dmel\CG9054,anon-79E,DmRH12,DDX1,DmDDX1,CG9054,Dbp79E)

Ddx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular biosynthetic process GO:0031327 277 0.520
negative regulation of transcription dna templated GO:0045892 237 0.448
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.385
negative regulation of rna biosynthetic process GO:1902679 240 0.352
negative regulation of rna metabolic process GO:0051253 251 0.293
negative regulation of nucleic acid templated transcription GO:1903507 240 0.277
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.270
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.262
chromatin organization GO:0006325 207 0.261
cellular protein modification process GO:0006464 438 0.185
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.144
negative regulation of biosynthetic process GO:0009890 277 0.129
histone modification GO:0016570 106 0.109
small molecule metabolic process GO:0044281 305 0.107
Human
protein modification process GO:0036211 438 0.106
negative regulation of cellular metabolic process GO:0031324 382 0.104
catabolic process GO:0009056 409 0.102
Human
dna repair GO:0006281 54 0.101
Human
chromatin modification GO:0016568 147 0.084
response to organic substance GO:0010033 284 0.076
Mouse
death GO:0016265 284 0.075
chromosome organization GO:0051276 360 0.075
cellular catabolic process GO:0044248 372 0.073
Human
regulation of protein metabolic process GO:0051246 256 0.069
intracellular signal transduction GO:0035556 300 0.067
cytoplasmic transport GO:0016482 130 0.065
regulation of catalytic activity GO:0050790 185 0.061
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.061
endocytosis GO:0006897 310 0.058
positive regulation of rna biosynthetic process GO:1902680 266 0.054
response to oxygen containing compound GO:1901700 200 0.052
regulation of cell death GO:0010941 173 0.051
positive regulation of biosynthetic process GO:0009891 316 0.048
regulation of molecular function GO:0065009 217 0.046
organic substance catabolic process GO:1901575 308 0.046
Human
protein localization GO:0008104 284 0.045
ribonucleotide metabolic process GO:0009259 145 0.045
Human
regulation of programmed cell death GO:0043067 152 0.044
chromatin remodeling GO:0006338 72 0.043
cell death GO:0008219 279 0.043
cellular response to dna damage stimulus GO:0006974 223 0.043
Human
organophosphate metabolic process GO:0019637 195 0.043
Human
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
positive regulation of protein metabolic process GO:0051247 128 0.041
positive regulation of molecular function GO:0044093 136 0.041
regulation of protein modification process GO:0031399 112 0.040
regulation of apoptotic process GO:0042981 130 0.038
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
Human
macromolecular complex assembly GO:0065003 256 0.036
transcription from rna polymerase ii promoter GO:0006366 368 0.036
organonitrogen compound metabolic process GO:1901564 318 0.034
Human
purine ribonucleotide metabolic process GO:0009150 145 0.033
Human
covalent chromatin modification GO:0016569 106 0.033
phosphorylation GO:0016310 294 0.033
double strand break repair via nonhomologous end joining GO:0006303 5 0.031
embryo development ending in birth or egg hatching GO:0009792 152 0.031
dna metabolic process GO:0006259 227 0.031
Human
oxoacid metabolic process GO:0043436 103 0.030
positive regulation of gene expression GO:0010628 290 0.030
macromolecule catabolic process GO:0009057 161 0.030
positive regulation of catalytic activity GO:0043085 118 0.030
nucleoside metabolic process GO:0009116 127 0.030
Human
nucleosome organization GO:0034728 59 0.029
organic substance transport GO:0071702 257 0.029
positive regulation of response to stimulus GO:0048584 323 0.028
anatomical structure homeostasis GO:0060249 97 0.028
positive regulation of cell death GO:0010942 69 0.027
phagocytosis GO:0006909 215 0.027
mrna metabolic process GO:0016071 124 0.026
regulation of hydrolase activity GO:0051336 97 0.026
apoptotic process GO:0006915 159 0.026
positive regulation of cellular protein metabolic process GO:0032270 118 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
Human
regulation of intracellular signal transduction GO:1902531 236 0.025
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
negative regulation of gene expression GO:0010629 387 0.024
positive regulation of programmed cell death GO:0043068 62 0.024
cellular protein localization GO:0034613 160 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
Human
nucleus organization GO:0006997 45 0.024
nucleotide metabolic process GO:0009117 161 0.024
Human
vesicle mediated transport GO:0016192 381 0.023
intracellular transport GO:0046907 228 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
response to biotic stimulus GO:0009607 294 0.023
Mouse
organic acid metabolic process GO:0006082 103 0.022
protein complex biogenesis GO:0070271 201 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
Human
defense response GO:0006952 300 0.021
positive regulation of rna metabolic process GO:0051254 271 0.021
protein phosphorylation GO:0006468 169 0.021
chromatin silencing GO:0006342 76 0.021
purine containing compound metabolic process GO:0072521 155 0.020
Human
aromatic compound catabolic process GO:0019439 166 0.019
Human
protein alkylation GO:0008213 43 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
Human
establishment of localization in cell GO:0051649 402 0.019
stem cell differentiation GO:0048863 117 0.019
negative regulation of gene expression epigenetic GO:0045814 77 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
Human
dna replication GO:0006260 48 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
Human
cellular response to organic substance GO:0071310 132 0.018
heterocycle catabolic process GO:0046700 166 0.018
Human
ribose phosphate metabolic process GO:0019693 145 0.018
Human
eye development GO:0001654 323 0.018
establishment of protein localization GO:0045184 163 0.017
protein complex assembly GO:0006461 200 0.017
peptidyl amino acid modification GO:0018193 105 0.017
positive regulation of organelle organization GO:0010638 65 0.017
negative regulation of developmental process GO:0051093 201 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
Human
regulation of mitotic cell cycle GO:0007346 190 0.017
programmed cell death GO:0012501 257 0.016
cell motility GO:0048870 251 0.016
regulation of meiosis GO:0040020 3 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
body morphogenesis GO:0010171 2 0.015
organophosphate catabolic process GO:0046434 112 0.015
Human
cellular response to chemical stimulus GO:0070887 199 0.015
cellular macromolecule localization GO:0070727 220 0.015
response to other organism GO:0051707 293 0.015
Mouse
camera type eye development GO:0043010 4 0.015
regulation of proteolysis GO:0030162 87 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
Human
regulation of protein ubiquitination GO:0031396 22 0.015
protein transport GO:0015031 155 0.014
tissue morphogenesis GO:0048729 297 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
Human
regulation of protein localization GO:0032880 76 0.014
regulation of cell cycle GO:0051726 291 0.014
homeostatic process GO:0042592 199 0.014
regulation of phosphorylation GO:0042325 147 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
positive regulation of cell communication GO:0010647 250 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
response to external biotic stimulus GO:0043207 293 0.013
Mouse
connective tissue development GO:0061448 3 0.013
single organism intracellular transport GO:1902582 207 0.013
regulation of cell cycle process GO:0010564 181 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
protein catabolic process GO:0030163 101 0.013
positive regulation of signal transduction GO:0009967 223 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.012
Human
negative regulation of catabolic process GO:0009895 36 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
nucleoside catabolic process GO:0009164 112 0.012
Human
purine ribonucleoside catabolic process GO:0046130 112 0.012
Human
atp dependent chromatin remodeling GO:0043044 22 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
Human
ras protein signal transduction GO:0007265 88 0.012
regulation of cell proliferation GO:0042127 163 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
Human
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
cell division GO:0051301 248 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
rna processing GO:0006396 147 0.011
Human
neurological system process GO:0050877 358 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
Human
regulation of protein stability GO:0031647 43 0.011
histone methylation GO:0016571 40 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
Human
regulation of chromosome organization GO:0033044 64 0.011
positive regulation of signaling GO:0023056 243 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
Human
purine ribonucleoside metabolic process GO:0046128 127 0.011
Human
methylation GO:0032259 47 0.011
mrna processing GO:0006397 104 0.011
heart development GO:0007507 82 0.011
protein processing GO:0016485 68 0.011
cell proliferation GO:0008283 299 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of response to stress GO:0080134 200 0.011
double strand break repair GO:0006302 26 0.011
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
appendage morphogenesis GO:0035107 397 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
appendage development GO:0048736 401 0.010
jak stat cascade GO:0007259 49 0.010
intracellular protein transport GO:0006886 104 0.010
macromolecule methylation GO:0043414 45 0.010
chromatin assembly or disassembly GO:0006333 52 0.010
regulation of organelle organization GO:0033043 196 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
negative regulation of signaling GO:0023057 219 0.010
regulation of establishment of protein localization GO:0070201 61 0.010

Ddx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.046
disease of anatomical entity DOID:7 0 0.040
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.015
nervous system disease DOID:863 0 0.012