Drosophila melanogaster

79 known processes

Lsd-2 (Dmel_CG9057)

Lipid storage droplet-2

(Aliases: Dmel\CG9057,145098_at,Lsd2,CG9057,LSD-2,LSD2)

Lsd-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of lipid storage GO:0010883 22 0.848
lipid localization GO:0010876 54 0.422
regulation of sequestering of triglyceride GO:0010889 3 0.388
lipid catabolic process GO:0016042 21 0.368
acylglycerol metabolic process GO:0006639 12 0.353
triglyceride metabolic process GO:0006641 12 0.353
cellular lipid metabolic process GO:0044255 83 0.352
positive regulation of lipid storage GO:0010884 4 0.351
actin cytoskeleton organization GO:0030036 206 0.324
neutral lipid metabolic process GO:0006638 12 0.308
cellular macromolecule localization GO:0070727 220 0.285
regulation of lipid metabolic process GO:0019216 15 0.285
cellular response to external stimulus GO:0071496 66 0.239
lipid modification GO:0030258 24 0.215
single organism catabolic process GO:0044712 228 0.210
chemical homeostasis GO:0048878 92 0.208
acylglycerol catabolic process GO:0046464 3 0.202
lipid storage GO:0019915 38 0.200
maintenance of location GO:0051235 73 0.199
response to starvation GO:0042594 97 0.185
lipid metabolic process GO:0006629 121 0.184
regulation of cellular component biogenesis GO:0044087 201 0.183
intracellular transport GO:0046907 228 0.177
catabolic process GO:0009056 409 0.176
glycerolipid metabolic process GO:0046486 34 0.167
small molecule metabolic process GO:0044281 305 0.160
establishment of localization in cell GO:0051649 402 0.152
response to monosaccharide GO:0034284 4 0.144
lipid biosynthetic process GO:0008610 46 0.135
regulation of transport GO:0051049 181 0.134
establishment of protein localization GO:0045184 163 0.123
organic substance transport GO:0071702 257 0.122
oxoacid metabolic process GO:0043436 103 0.122
regulation of synapse assembly GO:0051963 94 0.122
vesicle mediated transport GO:0016192 381 0.122
actin filament based process GO:0030029 220 0.114
intracellular protein transport GO:0006886 104 0.109
positive regulation of lipid metabolic process GO:0045834 4 0.108
response to abiotic stimulus GO:0009628 341 0.107
regulation of localization GO:0032879 275 0.104
response to biotic stimulus GO:0009607 294 0.103
positive regulation of developmental process GO:0051094 143 0.099
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.096
phagocytosis recognition GO:0006910 1 0.096
neurological system process GO:0050877 358 0.095
fatty acid oxidation GO:0019395 6 0.094
histolysis GO:0007559 102 0.093
actomyosin structure organization GO:0031032 56 0.092
positive regulation of biosynthetic process GO:0009891 316 0.089
cellular catabolic process GO:0044248 372 0.083
cellular lipid catabolic process GO:0044242 16 0.083
telencephalon development GO:0021537 2 0.083
response to lipopolysaccharide GO:0032496 4 0.082
monocarboxylic acid catabolic process GO:0072329 10 0.077
cellular response to lipopolysaccharide GO:0071222 3 0.077
negative regulation of cellular biosynthetic process GO:0031327 277 0.077
associative learning GO:0008306 65 0.076
cellular response to endogenous stimulus GO:0071495 80 0.075
forebrain development GO:0030900 2 0.070
single organism intracellular transport GO:1902582 207 0.068
actin filament bundle organization GO:0061572 28 0.067
cellular protein localization GO:0034613 160 0.065
organic acid metabolic process GO:0006082 103 0.064
protein localization GO:0008104 284 0.064
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.064
adult somatic muscle development GO:0007527 14 0.063
cellular response to peptide GO:1901653 28 0.062
muscle cell differentiation GO:0042692 103 0.062
triglyceride catabolic process GO:0019433 3 0.061
regulation of synapse organization GO:0050807 110 0.061
cell death GO:0008219 279 0.061
actin filament organization GO:0007015 126 0.061
developmental programmed cell death GO:0010623 138 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.058
tissue death GO:0016271 102 0.058
fatty acid metabolic process GO:0006631 20 0.058
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.057
positive regulation of gene expression GO:0010628 290 0.057
oxidation reduction process GO:0055114 123 0.054
regulation of immune system process GO:0002682 176 0.054
germarium derived egg chamber formation GO:0007293 101 0.053
fatty acid beta oxidation GO:0006635 6 0.053
positive regulation of cellular biosynthetic process GO:0031328 316 0.052
response to acid chemical GO:0001101 25 0.052
autophagic cell death GO:0048102 83 0.052
regulation of intracellular transport GO:0032386 64 0.052
sterol homeostasis GO:0055092 4 0.052
single organism biosynthetic process GO:0044711 206 0.051
open tracheal system development GO:0007424 204 0.049
response to organonitrogen compound GO:0010243 75 0.049
positive regulation of rho gtpase activity GO:0032321 19 0.048
regulation of multicellular organismal development GO:2000026 414 0.048
cellular response to chemical stimulus GO:0070887 199 0.047
synapse assembly GO:0007416 143 0.045
cellular ketone metabolic process GO:0042180 24 0.045
heart development GO:0007507 82 0.044
neutral lipid catabolic process GO:0046461 3 0.043
synaptic growth at neuromuscular junction GO:0051124 119 0.043
immune effector process GO:0002252 98 0.042
regulation of cellular ketone metabolic process GO:0010565 3 0.041
positive regulation of transport GO:0051050 92 0.041
brain development GO:0007420 120 0.041
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
response to endogenous stimulus GO:0009719 119 0.039
heterocycle catabolic process GO:0046700 166 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.039
response to extracellular stimulus GO:0009991 116 0.039
guanosine containing compound catabolic process GO:1901069 74 0.039
membrane organization GO:0061024 112 0.038
cell motility GO:0048870 251 0.038
regulation of rna splicing GO:0043484 69 0.038
regulation of establishment of protein localization GO:0070201 61 0.037
response to oxygen containing compound GO:1901700 200 0.037
response to other organism GO:0051707 293 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
response to glucose GO:0009749 2 0.036
cellular response to nutrient levels GO:0031669 62 0.036
glycerolipid catabolic process GO:0046503 3 0.036
endocytosis GO:0006897 310 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
organophosphate metabolic process GO:0019637 195 0.036
macromolecule catabolic process GO:0009057 161 0.035
response to organic substance GO:0010033 284 0.035
phagocytosis GO:0006909 215 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
muscle structure development GO:0061061 224 0.034
circulatory system development GO:0072359 82 0.034
salivary gland morphogenesis GO:0007435 145 0.034
head development GO:0060322 135 0.034
regulation of synapse structure and activity GO:0050803 128 0.034
regulation of cell proliferation GO:0042127 163 0.034
glycosyl compound metabolic process GO:1901657 127 0.034
regulation of molecular function GO:0065009 217 0.034
regulation of nervous system development GO:0051960 248 0.034
mitochondrion organization GO:0007005 65 0.033
purine nucleoside triphosphate catabolic process GO:0009146 108 0.033
protein transport GO:0015031 155 0.033
synapse organization GO:0050808 196 0.033
cellular response to decreased oxygen levels GO:0036294 30 0.033
positive regulation of rna biosynthetic process GO:1902680 266 0.033
homeostatic process GO:0042592 199 0.033
negative regulation of growth GO:0045926 84 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
negative regulation of protein metabolic process GO:0051248 85 0.032
salivary gland cell autophagic cell death GO:0035071 83 0.032
acylglycerol biosynthetic process GO:0046463 2 0.031
negative regulation of cell communication GO:0010648 223 0.031
cellular response to oxygen containing compound GO:1901701 79 0.031
negative regulation of signal transduction GO:0009968 206 0.031
single organism membrane organization GO:0044802 93 0.030
cellular response to starvation GO:0009267 61 0.030
cellular response to peptide hormone stimulus GO:0071375 28 0.030
immune response regulating signaling pathway GO:0002764 2 0.030
regulation of cytoplasmic transport GO:1903649 47 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
regionalization GO:0003002 416 0.029
protein modification process GO:0036211 438 0.029
endomembrane system organization GO:0010256 119 0.028
asymmetric cell division GO:0008356 37 0.028
regulation of actin filament based process GO:0032970 42 0.028
aromatic compound catabolic process GO:0019439 166 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
regulation of catalytic activity GO:0050790 185 0.028
rho protein signal transduction GO:0007266 14 0.028
organic substance catabolic process GO:1901575 308 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.027
fatty acid catabolic process GO:0009062 9 0.027
cellular response to biotic stimulus GO:0071216 4 0.026
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.026
body morphogenesis GO:0010171 2 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
somatic muscle development GO:0007525 66 0.025
regulation of organelle organization GO:0033043 196 0.025
response to nitrogen compound GO:1901698 90 0.025
neuron recognition GO:0008038 101 0.025
protein targeting to nucleus GO:0044744 51 0.025
cellular response to organic substance GO:0071310 132 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
cellular response to oxygen levels GO:0071453 30 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
gtp catabolic process GO:0006184 72 0.024
germarium derived oocyte fate determination GO:0007294 26 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.024
epithelial cell differentiation GO:0030855 322 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
response to desiccation GO:0009269 3 0.024
exocrine system development GO:0035272 162 0.023
regulation of sequestering of calcium ion GO:0051282 3 0.023
positive regulation of cell migration GO:0030335 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
cellular response to extracellular stimulus GO:0031668 64 0.023
wound healing GO:0042060 75 0.023
response to light stimulus GO:0009416 124 0.023
response to water deprivation GO:0009414 4 0.023
calcium ion homeostasis GO:0055074 23 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
protein catabolic process GO:0030163 101 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.022
wing disc morphogenesis GO:0007472 344 0.022
striated muscle cell differentiation GO:0051146 90 0.022
short term memory GO:0007614 19 0.022
behavioral response to ethanol GO:0048149 49 0.022
regulation of cellular localization GO:0060341 136 0.022
ribose phosphate metabolic process GO:0019693 145 0.021
cardiovascular system development GO:0072358 82 0.021
segmentation GO:0035282 207 0.021
cellular response to molecule of bacterial origin GO:0071219 3 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
regulation of lipid biosynthetic process GO:0046890 6 0.021
appendage morphogenesis GO:0035107 397 0.021
cardiocyte differentiation GO:0035051 29 0.021
cellular response to organonitrogen compound GO:0071417 36 0.020
regulation of nucleocytoplasmic transport GO:0046822 35 0.020
cell recognition GO:0008037 102 0.020
protein import GO:0017038 55 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
mitotic spindle organization GO:0007052 220 0.020
protein localization to organelle GO:0033365 82 0.020
insulin receptor signaling pathway GO:0008286 25 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
lipid particle organization GO:0034389 7 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
regulation of intracellular protein transport GO:0033157 46 0.019
striated muscle cell development GO:0055002 50 0.019
receptor mediated endocytosis GO:0006898 21 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
organic acid catabolic process GO:0016054 16 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
death GO:0016265 284 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
single organism cellular localization GO:1902580 180 0.019
spermatogenesis GO:0007283 200 0.019
phosphatidic acid metabolic process GO:0046473 1 0.019
response to osmotic stress GO:0006970 14 0.019
response to anesthetic GO:0072347 9 0.018
detection of external stimulus GO:0009581 66 0.018
cellular amine metabolic process GO:0044106 12 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
purine containing compound catabolic process GO:0072523 112 0.018
triglyceride biosynthetic process GO:0019432 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
cellular response to hormone stimulus GO:0032870 44 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
developmental growth GO:0048589 280 0.018
malpighian tubule development GO:0072002 64 0.018
response to drug GO:0042493 17 0.018
regulation of secretion GO:0051046 44 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
polysaccharide metabolic process GO:0005976 11 0.017
lipid homeostasis GO:0055088 33 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
carboxylic acid catabolic process GO:0046395 16 0.017
eye photoreceptor cell development GO:0042462 81 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
positive regulation of catabolic process GO:0009896 105 0.017
positive regulation of cell motility GO:2000147 3 0.017
response to uv GO:0009411 24 0.017
taxis GO:0042330 304 0.017
apoptotic cell clearance GO:0043277 14 0.017
steroid metabolic process GO:0008202 20 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
monovalent inorganic cation transport GO:0015672 40 0.017
nucleoside catabolic process GO:0009164 112 0.017
detection of light stimulus GO:0009583 58 0.017
growth GO:0040007 359 0.017
aging GO:0007568 143 0.016
cation transport GO:0006812 110 0.016
regulation of nucleoside metabolic process GO:0009118 50 0.016
monocarboxylic acid metabolic process GO:0032787 29 0.016
response to hexose GO:0009746 3 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
immune response GO:0006955 246 0.016
regulation of protein localization GO:0032880 76 0.016
thermotaxis GO:0043052 16 0.016
positive regulation of cell communication GO:0010647 250 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
regulation of cytoskeleton organization GO:0051493 89 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
organelle assembly GO:0070925 198 0.016
single organism nuclear import GO:1902593 51 0.016
regulation of purine nucleotide catabolic process GO:0033121 48 0.016
anterior posterior axis specification GO:0009948 109 0.016
cellular response to sterol depletion GO:0071501 3 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
cell proliferation GO:0008283 299 0.016
cuticle development GO:0042335 86 0.016
single organism behavior GO:0044708 391 0.015
regulation of cell projection organization GO:0031344 92 0.015
regulation of growth GO:0040008 233 0.015
neutral lipid biosynthetic process GO:0046460 2 0.015
ion transport GO:0006811 145 0.015
macromolecular complex assembly GO:0065003 256 0.015
secretion GO:0046903 109 0.015
skeletal muscle fiber development GO:0048741 3 0.015
oocyte fate determination GO:0030716 27 0.015
regulation of actin cytoskeleton organization GO:0032956 42 0.015
lateral inhibition GO:0046331 206 0.015
cellular homeostasis GO:0019725 80 0.015
amine metabolic process GO:0009308 12 0.015
gland morphogenesis GO:0022612 145 0.015
regulation of cellular catabolic process GO:0031329 157 0.014
rna localization GO:0006403 115 0.014
response to peptide GO:1901652 29 0.014
regulation of cellular component size GO:0032535 98 0.014
metal ion transport GO:0030001 74 0.014
cholesterol transport GO:0030301 2 0.014
response to temperature stimulus GO:0009266 106 0.014
golgi localization GO:0051645 2 0.014
cellular response to hypoxia GO:0071456 28 0.014
response to wounding GO:0009611 94 0.014
autophagy GO:0006914 108 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
lipid oxidation GO:0034440 7 0.014
regulation of cell cycle GO:0051726 291 0.014
protein import into nucleus GO:0006606 51 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
acyl coa metabolic process GO:0006637 3 0.014
cell growth GO:0016049 108 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
innate immune response GO:0045087 144 0.013
intracellular protein transmembrane transport GO:0065002 4 0.013
connective tissue development GO:0061448 3 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
regulation of cell differentiation GO:0045595 302 0.013
salivary gland development GO:0007431 162 0.013
adherens junction organization GO:0034332 27 0.013
positive regulation of mitotic cell cycle GO:0045931 34 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
dorsal ventral axis specification GO:0009950 66 0.013
organophosphate catabolic process GO:0046434 112 0.013
response to hypoxia GO:0001666 53 0.013
response to unfolded protein GO:0006986 9 0.013
regulation of steroid metabolic process GO:0019218 2 0.013
regulation of apoptotic process GO:0042981 130 0.013
nucleotide metabolic process GO:0009117 161 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
mesenchymal cell development GO:0014031 1 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
response to inorganic substance GO:0010035 44 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
regulation of protein transport GO:0051223 57 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of protein import into nucleus GO:0042306 28 0.012
appendage development GO:0048736 401 0.012
detection of chemical stimulus GO:0009593 93 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
striated muscle myosin thick filament assembly GO:0071688 3 0.012
axis specification GO:0009798 167 0.012
regulation of secretion by cell GO:1903530 39 0.012
positive regulation of secretion GO:0051047 22 0.012
establishment of ommatidial planar polarity GO:0042067 49 0.012
cellular response to insulin stimulus GO:0032869 28 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
positive regulation of epithelial cell differentiation GO:0030858 1 0.012
autophagic vacuole assembly GO:0000045 2 0.012
long chain fatty acid metabolic process GO:0001676 3 0.012
positive regulation of molecular function GO:0044093 136 0.012
biological adhesion GO:0022610 138 0.012
carotenoid metabolic process GO:0016116 1 0.012
positive regulation of signal transduction GO:0009967 223 0.012
regulation of epidermal cell differentiation GO:0045604 3 0.011
positive regulation of nervous system development GO:0051962 69 0.011
response to external biotic stimulus GO:0043207 293 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
detection of stimulus GO:0051606 156 0.011
regulation of microtubule based process GO:0032886 49 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
response to peptide hormone GO:0043434 29 0.011
microtubule based transport GO:0010970 42 0.011
endosomal transport GO:0016197 44 0.011
cilium assembly GO:0042384 38 0.011
regulation of protein localization to nucleus GO:1900180 29 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
regulation of neuron projection development GO:0010975 69 0.011
neuromuscular junction development GO:0007528 149 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
response to radiation GO:0009314 155 0.011
imaginal disc growth GO:0007446 37 0.011
protein complex localization GO:0031503 4 0.011
response to bacterium GO:0009617 198 0.011
establishment of planar polarity GO:0001736 87 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
negative regulation of translation GO:0017148 28 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
hindbrain development GO:0030902 2 0.010
regulation of immune response GO:0050776 118 0.010
negative regulation of nervous system development GO:0051961 92 0.010
regulation of cell fate commitment GO:0010453 29 0.010
macroautophagy GO:0016236 42 0.010
sensory perception GO:0007600 196 0.010
eye morphogenesis GO:0048592 260 0.010
negative regulation of developmental process GO:0051093 201 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
wing disc pattern formation GO:0035222 66 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
nuclear import GO:0051170 51 0.010
alcohol biosynthetic process GO:0046165 14 0.010

Lsd-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
disease of metabolism DOID:0014667 0 0.016
musculoskeletal system disease DOID:17 0 0.016
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
acquired metabolic disease DOID:0060158 0 0.014