Drosophila melanogaster

8 known processes

thoc6 (Dmel_CG5632)

CG5632 gene product from transcript CG5632-RA

(Aliases: CG5632,Dmel\CG5632,THOC6)

thoc6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 291 0.059
cellular catabolic process GO:0044248 372 0.050
organic substance catabolic process GO:1901575 308 0.049
catabolic process GO:0009056 409 0.048
organonitrogen compound metabolic process GO:1901564 318 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.046
mitotic nuclear division GO:0007067 213 0.043
negative regulation of cellular metabolic process GO:0031324 382 0.042
protein modification process GO:0036211 438 0.042
nuclear division GO:0000280 332 0.042
chromosome organization GO:0051276 360 0.040
neurological system process GO:0050877 358 0.039
organelle fission GO:0048285 340 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
cell cycle phase transition GO:0044770 140 0.038
regulation of response to stress GO:0080134 200 0.036
negative regulation of gene expression GO:0010629 387 0.036
cell proliferation GO:0008283 299 0.035
regulation of mitotic cell cycle GO:0007346 190 0.034
establishment of localization in cell GO:0051649 402 0.033
Human
cell death GO:0008219 279 0.033
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
regulation of cell cycle process GO:0010564 181 0.033
single organism catabolic process GO:0044712 228 0.032
death GO:0016265 284 0.032
Human
macromolecule catabolic process GO:0009057 161 0.031
small molecule metabolic process GO:0044281 305 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
negative regulation of cellular biosynthetic process GO:0031327 277 0.031
positive regulation of response to stimulus GO:0048584 323 0.030
taxis GO:0042330 304 0.030
rna processing GO:0006396 147 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
cellular protein modification process GO:0006464 438 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
response to biotic stimulus GO:0009607 294 0.028
epithelial cell development GO:0002064 274 0.028
chromosome segregation GO:0007059 157 0.027
endocytosis GO:0006897 310 0.027
response to external biotic stimulus GO:0043207 293 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
salivary gland development GO:0007431 162 0.027
organic acid metabolic process GO:0006082 103 0.027
gland morphogenesis GO:0022612 145 0.027
mitotic cell cycle phase transition GO:0044772 138 0.026
response to organic substance GO:0010033 284 0.026
negative regulation of cell communication GO:0010648 223 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.026
dendrite development GO:0016358 204 0.026
proteolysis GO:0006508 192 0.025
macromolecular complex assembly GO:0065003 256 0.025
organic substance transport GO:0071702 257 0.025
Human
programmed cell death GO:0012501 257 0.025
Human
developmental programmed cell death GO:0010623 138 0.025
regulation of catabolic process GO:0009894 170 0.025
immune system process GO:0002376 347 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
response to other organism GO:0051707 293 0.025
epithelial cell differentiation GO:0030855 322 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
response to abiotic stimulus GO:0009628 341 0.024
positive regulation of cell communication GO:0010647 250 0.024
cell division GO:0051301 248 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
appendage development GO:0048736 401 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
regulation of mrna metabolic process GO:1903311 72 0.024
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
intracellular signal transduction GO:0035556 300 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
protein maturation GO:0051604 71 0.024
positive regulation of rna metabolic process GO:0051254 271 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
response to lipopolysaccharide GO:0032496 4 0.023
positive regulation of gene expression GO:0010628 290 0.023
chromatin organization GO:0006325 207 0.023
gene silencing GO:0016458 138 0.023
negative regulation of signaling GO:0023057 219 0.023
mrna processing GO:0006397 104 0.023
regionalization GO:0003002 416 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
appendage morphogenesis GO:0035107 397 0.023
camera type eye development GO:0043010 4 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.022
negative regulation of developmental process GO:0051093 201 0.022
vesicle mediated transport GO:0016192 381 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of cell differentiation GO:0045595 302 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
protein localization GO:0008104 284 0.022
cell cell signaling involved in cell fate commitment GO:0045168 210 0.022
wing disc morphogenesis GO:0007472 344 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
phagocytosis GO:0006909 215 0.022
compound eye development GO:0048749 307 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
mrna metabolic process GO:0016071 124 0.021
positive regulation of signaling GO:0023056 243 0.021
regulation of cellular response to stress GO:0080135 89 0.021
single organism biosynthetic process GO:0044711 206 0.021
regulation of gene expression epigenetic GO:0040029 128 0.021
regulation of molecular function GO:0065009 217 0.021
eye development GO:0001654 323 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
phosphorylation GO:0016310 294 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
regulation of gene silencing GO:0060968 63 0.020
lateral inhibition GO:0046331 206 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
oxoacid metabolic process GO:0043436 103 0.020
sister chromatid segregation GO:0000819 92 0.020
heterocycle catabolic process GO:0046700 166 0.020
regulation of protein metabolic process GO:0051246 256 0.020
negative regulation of signal transduction GO:0009968 206 0.020
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.020
organic cyclic compound catabolic process GO:1901361 168 0.019
immune response GO:0006955 246 0.019
regulation of immune system process GO:0002682 176 0.019
localization of cell GO:0051674 257 0.019
dendrite morphogenesis GO:0048813 199 0.019
regulation of localization GO:0032879 275 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
response to bacterium GO:0009617 198 0.019
sensory perception GO:0007600 196 0.019
rna splicing GO:0008380 83 0.019
ovarian follicle cell development GO:0030707 248 0.019
digestive tract morphogenesis GO:0048546 127 0.019
cellular protein catabolic process GO:0044257 83 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
cellular amine metabolic process GO:0044106 12 0.019
forebrain development GO:0030900 2 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
salivary gland morphogenesis GO:0007435 145 0.019
amine metabolic process GO:0009308 12 0.019
cellular ketone metabolic process GO:0042180 24 0.018
response to radiation GO:0009314 155 0.018
aromatic compound catabolic process GO:0019439 166 0.018
positive regulation of signal transduction GO:0009967 223 0.018
regulation of mrna splicing via spliceosome GO:0048024 64 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
negative regulation of cell cycle GO:0045786 116 0.017
exocrine system development GO:0035272 162 0.017
mitotic sister chromatid separation GO:0051306 30 0.017
body morphogenesis GO:0010171 2 0.017
regulation of mitosis GO:0007088 56 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
alternative mrna splicing via spliceosome GO:0000380 60 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
regulation of apoptotic process GO:0042981 130 0.017
Human
regulation of rna splicing GO:0043484 69 0.017
defense response to other organism GO:0098542 225 0.017
homeostatic process GO:0042592 199 0.017
ion transport GO:0006811 145 0.017
protein catabolic process GO:0030163 101 0.017
tissue morphogenesis GO:0048729 297 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.017
synaptic transmission GO:0007268 288 0.017
nucleoside metabolic process GO:0009116 127 0.017
defense response GO:0006952 300 0.017
mrna splicing via spliceosome GO:0000398 73 0.016
tissue death GO:0016271 102 0.016
actin filament based process GO:0030029 220 0.016
regulation of mrna processing GO:0050684 71 0.016
axon development GO:0061564 297 0.016
compound eye morphogenesis GO:0001745 249 0.016
histolysis GO:0007559 102 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.016
regulation of catalytic activity GO:0050790 185 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
negative regulation of gene expression epigenetic GO:0045814 77 0.016
chemosensory behavior GO:0007635 106 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
mitotic sister chromatid segregation GO:0000070 87 0.016
apoptotic process GO:0006915 159 0.016
Human
intracellular transport GO:0046907 228 0.016
Human
purine nucleotide metabolic process GO:0006163 146 0.015
rna splicing via transesterification reactions GO:0000375 73 0.015
regulation of organelle organization GO:0033043 196 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
organophosphate metabolic process GO:0019637 195 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
growth GO:0040007 359 0.015
positive regulation of cell migration GO:0030335 2 0.015
positive regulation of cell motility GO:2000147 3 0.015
regulation of transport GO:0051049 181 0.014
regulation of cell proliferation GO:0042127 163 0.014
cell maturation GO:0048469 144 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
single organism cellular localization GO:1902580 180 0.014
chemotaxis GO:0006935 249 0.014
organelle assembly GO:0070925 198 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of cell death GO:0010941 173 0.014
Human
nucleotide metabolic process GO:0009117 161 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
connective tissue development GO:0061448 3 0.014
regulation of proteolysis GO:0030162 87 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
protein phosphorylation GO:0006468 169 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
axonogenesis GO:0007409 290 0.014
single organism behavior GO:0044708 391 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.014
chromatin silencing GO:0006342 76 0.014
innate immune response GO:0045087 144 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
rna localization GO:0006403 115 0.014
Human
cellular macromolecule localization GO:0070727 220 0.014
dna metabolic process GO:0006259 227 0.014
gland development GO:0048732 191 0.014
cognition GO:0050890 141 0.014
segmentation GO:0035282 207 0.014
endomembrane system organization GO:0010256 119 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
sensory organ morphogenesis GO:0090596 260 0.014
negative regulation of organelle organization GO:0010639 56 0.014
hindbrain development GO:0030902 2 0.014
salivary gland histolysis GO:0035070 88 0.014
multi organism behavior GO:0051705 175 0.014
response to monosaccharide GO:0034284 4 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of cell division GO:0051302 72 0.014
neuron projection guidance GO:0097485 241 0.014
cell migration GO:0016477 238 0.013
cellular protein localization GO:0034613 160 0.013
protein processing GO:0016485 68 0.013
tube morphogenesis GO:0035239 191 0.013
sensory perception of smell GO:0007608 80 0.013
telencephalon development GO:0021537 2 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
regulation of immune response GO:0050776 118 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
peptide metabolic process GO:0006518 80 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
regulation of defense response GO:0031347 102 0.013
regulation of protein catabolic process GO:0042176 55 0.013
establishment of protein localization GO:0045184 163 0.013
olfactory behavior GO:0042048 97 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
chromosome separation GO:0051304 42 0.013
cell motility GO:0048870 251 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
mitotic spindle organization GO:0007052 220 0.013
response to temperature stimulus GO:0009266 106 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
chromatin modification GO:0016568 147 0.013
ameboidal type cell migration GO:0001667 151 0.013
response to glucose GO:0009749 2 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of nuclear division GO:0051783 58 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
regulation of programmed cell death GO:0043067 152 0.012
Human
response to hexose GO:0009746 3 0.012
developmental maturation GO:0021700 172 0.012
autophagic cell death GO:0048102 83 0.012
golgi organization GO:0007030 66 0.012
eye morphogenesis GO:0048592 260 0.012
humoral immune response GO:0006959 117 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
protein transport GO:0015031 155 0.012
positive regulation of defense response GO:0031349 59 0.012
cellular response to organic substance GO:0071310 132 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
response to nutrient levels GO:0031667 114 0.012
actin cytoskeleton organization GO:0030036 206 0.012
centrosome organization GO:0051297 163 0.012
organelle localization GO:0051640 148 0.012
locomotory behavior GO:0007626 176 0.012
sensory perception of chemical stimulus GO:0007606 116 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
kidney development GO:0001822 3 0.012
antimicrobial humoral response GO:0019730 99 0.012
maintenance of location GO:0051235 73 0.012
ras protein signal transduction GO:0007265 88 0.012
synapse organization GO:0050808 196 0.012
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
developmental growth GO:0048589 280 0.011
spindle organization GO:0007051 253 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
purine containing compound metabolic process GO:0072521 155 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
cellular amide metabolic process GO:0043603 80 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
tube development GO:0035295 244 0.011
purine containing compound catabolic process GO:0072523 112 0.011
multi multicellular organism process GO:0044706 123 0.011
negative regulation of cell death GO:0060548 81 0.011
Human
organonitrogen compound catabolic process GO:1901565 128 0.011
protein dna complex subunit organization GO:0071824 86 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.011
response to oxygen containing compound GO:1901700 200 0.011
positive regulation of molecular function GO:0044093 136 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
regulation of innate immune response GO:0045088 71 0.011
regulation of synapse organization GO:0050807 110 0.011
dna repair GO:0006281 54 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
single organism intracellular transport GO:1902582 207 0.011
cation transport GO:0006812 110 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
nucleoside catabolic process GO:0009164 112 0.011
biological adhesion GO:0022610 138 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
learning GO:0007612 75 0.011
peptidyl amino acid modification GO:0018193 105 0.011
meiotic cell cycle GO:0051321 171 0.011
transmembrane transport GO:0055085 139 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
oocyte development GO:0048599 124 0.011
protein complex assembly GO:0006461 200 0.011
cellular homeostasis GO:0019725 80 0.011
hormone catabolic process GO:0042447 3 0.011
axis specification GO:0009798 167 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of cell projection organization GO:0031344 92 0.011
organophosphate catabolic process GO:0046434 112 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
detection of stimulus GO:0051606 156 0.010
protein complex biogenesis GO:0070271 201 0.010
regulation of cellular localization GO:0060341 136 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
defense response to bacterium GO:0042742 178 0.010
imaginal disc pattern formation GO:0007447 91 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010
olfactory learning GO:0008355 56 0.010
positive regulation of catabolic process GO:0009896 105 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
Human
cell growth GO:0016049 108 0.010
cytoplasmic transport GO:0016482 130 0.010
Human
nucleocytoplasmic transport GO:0006913 72 0.010
Human
ribonucleotide catabolic process GO:0009261 109 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
membrane organization GO:0061024 112 0.010
axon guidance GO:0007411 233 0.010
nucleotide catabolic process GO:0009166 109 0.010
cell adhesion GO:0007155 136 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
androgen metabolic process GO:0008209 1 0.010
carbohydrate metabolic process GO:0005975 82 0.010
regulation of proteasomal protein catabolic process GO:0061136 39 0.010
negative regulation of homeostatic process GO:0032845 2 0.010
learning or memory GO:0007611 141 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
centrosome cycle GO:0007098 137 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
cell cycle checkpoint GO:0000075 95 0.010
response to extracellular stimulus GO:0009991 116 0.010
anatomical structure homeostasis GO:0060249 97 0.010
response to endogenous stimulus GO:0009719 119 0.010

thoc6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.010
inherited metabolic disorder DOID:655 0 0.010