Drosophila melanogaster

19 known processes

IM4 (Dmel_CG15231)

Immune induced molecule 4

(Aliases: DIM-4,Dmel\CG15231,BcDNA:RH25931,DIM4,CG15231)

IM4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
humoral immune response GO:0006959 117 0.688
response to bacterium GO:0009617 198 0.602
defense response to bacterium GO:0042742 178 0.506
antibacterial humoral response GO:0019731 44 0.497
defense response to other organism GO:0098542 225 0.382
response to external biotic stimulus GO:0043207 293 0.325
activation of innate immune response GO:0002218 4 0.315
antifungal humoral response GO:0019732 12 0.249
response to other organism GO:0051707 293 0.242
defense response to gram positive bacterium GO:0050830 41 0.231
defense response to fungus GO:0050832 48 0.230
response to biotic stimulus GO:0009607 294 0.197
innate immune response activating signal transduction GO:0002758 2 0.152
defense response GO:0006952 300 0.143
immune system process GO:0002376 347 0.126
immune response GO:0006955 246 0.125
regulation of defense response GO:0031347 102 0.122
pattern recognition receptor signaling pathway GO:0002221 2 0.115
positive regulation of defense response GO:0031349 59 0.102
innate immune response GO:0045087 144 0.076
regulation of innate immune response GO:0045088 71 0.065
organonitrogen compound metabolic process GO:1901564 318 0.057
response to lipopolysaccharide GO:0032496 4 0.053
regulation of response to stress GO:0080134 200 0.053
defense response to gram negative bacterium GO:0050829 94 0.047
killing of cells of other organism GO:0031640 1 0.046
antimicrobial humoral response GO:0019730 99 0.044
peptidoglycan metabolic process GO:0000270 3 0.041
response to fungus GO:0009620 50 0.038
macromolecule catabolic process GO:0009057 161 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
regulation of intracellular signal transduction GO:1902531 236 0.036
response to abiotic stimulus GO:0009628 341 0.036
axis specification GO:0009798 167 0.035
regulation of immune response GO:0050776 118 0.034
regionalization GO:0003002 416 0.033
imaginal disc derived appendage development GO:0048737 399 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
immune response activating signal transduction GO:0002757 2 0.031
immune response regulating signaling pathway GO:0002764 2 0.031
regulation of multicellular organismal development GO:2000026 414 0.030
wing disc morphogenesis GO:0007472 344 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
protein maturation GO:0051604 71 0.029
neurological system process GO:0050877 358 0.029
regulation of nervous system development GO:0051960 248 0.029
protein modification process GO:0036211 438 0.029
vesicle mediated transport GO:0016192 381 0.029
negative regulation of gene expression GO:0010629 387 0.028
regulation of immune system process GO:0002682 176 0.028
regulation of molecular function GO:0065009 217 0.027
cellular response to molecule of bacterial origin GO:0071219 3 0.027
appendage development GO:0048736 401 0.027
negative regulation of signal transduction GO:0009968 206 0.026
positive regulation of signal transduction GO:0009967 223 0.026
sensory perception of chemical stimulus GO:0007606 116 0.026
cellular response to lipopolysaccharide GO:0071222 3 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
actin filament based process GO:0030029 220 0.025
appendage morphogenesis GO:0035107 397 0.025
positive regulation of gene expression GO:0010628 290 0.024
negative regulation of defense response GO:0031348 35 0.024
body morphogenesis GO:0010171 2 0.024
homeostatic process GO:0042592 199 0.024
dorsal ventral axis specification GO:0009950 66 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.023
phagocytosis GO:0006909 215 0.023
endocytosis GO:0006897 310 0.022
regulation of multi organism process GO:0043900 131 0.022
regulation of catalytic activity GO:0050790 185 0.022
response to organophosphorus GO:0046683 2 0.021
organic substance catabolic process GO:1901575 308 0.021
positive regulation of signaling GO:0023056 243 0.021
positive regulation of cell communication GO:0010647 250 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
regulation of protein metabolic process GO:0051246 256 0.021
catabolic process GO:0009056 409 0.021
organelle fission GO:0048285 340 0.021
response to light stimulus GO:0009416 124 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
death GO:0016265 284 0.019
protein processing GO:0016485 68 0.019
phosphorylation GO:0016310 294 0.019
connective tissue development GO:0061448 3 0.019
oxoacid metabolic process GO:0043436 103 0.019
regulation of cell development GO:0060284 215 0.019
developmental growth GO:0048589 280 0.019
cellular ketone metabolic process GO:0042180 24 0.018
response to radiation GO:0009314 155 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
negative regulation of peptide hormone processing GO:0060570 1 0.018
regulation of neurogenesis GO:0050767 158 0.018
negative regulation of cell communication GO:0010648 223 0.018
response to organic substance GO:0010033 284 0.018
programmed cell death GO:0012501 257 0.018
chemosensory behavior GO:0007635 106 0.017
single organism behavior GO:0044708 391 0.017
biological adhesion GO:0022610 138 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
cell recognition GO:0008037 102 0.017
cellular protein modification process GO:0006464 438 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
negative regulation of signaling GO:0023057 219 0.017
regulation of cell differentiation GO:0045595 302 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
positive regulation of innate immune response GO:0045089 38 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
protein phosphorylation GO:0006468 169 0.016
organic substance transport GO:0071702 257 0.016
small molecule metabolic process GO:0044281 305 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
cellular catabolic process GO:0044248 372 0.015
sensory perception of smell GO:0007608 80 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
actin cytoskeleton organization GO:0030036 206 0.015
compound eye development GO:0048749 307 0.015
regulation of cell cycle GO:0051726 291 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
nuclear division GO:0000280 332 0.015
cation transport GO:0006812 110 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
cell proliferation GO:0008283 299 0.015
response to temperature stimulus GO:0009266 106 0.015
olfactory behavior GO:0042048 97 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
positive regulation of immune system process GO:0002684 68 0.015
regulation of response to external stimulus GO:0032101 115 0.014
taxis GO:0042330 304 0.014
positive regulation of antibacterial peptide production GO:0002803 20 0.014
cell death GO:0008219 279 0.014
gland morphogenesis GO:0022612 145 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
positive regulation of cell motility GO:2000147 3 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
response to nutrient levels GO:0031667 114 0.014
carboxylic acid metabolic process GO:0019752 92 0.013
regulation of defense response to bacterium GO:1900424 30 0.013
intracellular signal transduction GO:0035556 300 0.013
spindle organization GO:0007051 253 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
anatomical structure homeostasis GO:0060249 97 0.013
mitotic nuclear division GO:0007067 213 0.013
single organism biosynthetic process GO:0044711 206 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
vitamin metabolic process GO:0006766 2 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
purine containing compound metabolic process GO:0072521 155 0.013
positive regulation of molecular function GO:0044093 136 0.013
intracellular transport GO:0046907 228 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
amine metabolic process GO:0009308 12 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
sensory perception GO:0007600 196 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
forebrain development GO:0030900 2 0.012
anion homeostasis GO:0055081 3 0.012
ion transport GO:0006811 145 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
cell junction organization GO:0034330 57 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
regulation of anatomical structure size GO:0090066 163 0.012
single organism catabolic process GO:0044712 228 0.012
cell adhesion GO:0007155 136 0.012
ras protein signal transduction GO:0007265 88 0.012
single organism cell adhesion GO:0098602 47 0.012
chromosome organization GO:0051276 360 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.012
multicellular organismal homeostasis GO:0048871 41 0.011
melanization defense response GO:0035006 45 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
establishment of localization in cell GO:0051649 402 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
eye development GO:0001654 323 0.011
epithelium migration GO:0090132 148 0.011
chaeta development GO:0022416 97 0.011
regulation of proteolysis GO:0030162 87 0.011
chemotaxis GO:0006935 249 0.011
positive regulation of cell migration GO:0030335 2 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
cell division GO:0051301 248 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
cell cell junction organization GO:0045216 55 0.011
organic acid metabolic process GO:0006082 103 0.011
cell migration GO:0016477 238 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
secondary metabolic process GO:0019748 75 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
endomembrane system organization GO:0010256 119 0.011
organophosphate metabolic process GO:0019637 195 0.011
sensory organ morphogenesis GO:0090596 260 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
response to organic cyclic compound GO:0014070 89 0.010
sterol homeostasis GO:0055092 4 0.010
meiotic nuclear division GO:0007126 151 0.010
neuron recognition GO:0008038 101 0.010
metal ion transport GO:0030001 74 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
cellular macromolecule localization GO:0070727 220 0.010
negative regulation of molecular function GO:0044092 51 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
segmentation GO:0035282 207 0.010
response to extracellular stimulus GO:0009991 116 0.010
photoreceptor cell development GO:0042461 96 0.010
xenobiotic catabolic process GO:0042178 1 0.010
vitamin biosynthetic process GO:0009110 1 0.010

IM4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.046
disease of anatomical entity DOID:7 0 0.030
cardiovascular system disease DOID:1287 0 0.013
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.012
vascular disease DOID:178 0 0.010