Drosophila melanogaster

19 known processes

rev7 (Dmel_CG2948)

CG2948 gene product from transcript CG2948-RA

(Aliases: CG2948,Dmel\CG2948,DmREV7,mad2B)

rev7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 291 0.630
regulation of defense response GO:0031347 102 0.421
immune system process GO:0002376 347 0.400
response to other organism GO:0051707 293 0.344
humoral immune response GO:0006959 117 0.309
protein modification process GO:0036211 438 0.276
response to biotic stimulus GO:0009607 294 0.275
defense response to other organism GO:0098542 225 0.260
regulation of immune response GO:0050776 118 0.257
response to external biotic stimulus GO:0043207 293 0.232
innate immune response GO:0045087 144 0.215
cell adhesion involved in heart morphogenesis GO:0061343 12 0.212
antimicrobial humoral response GO:0019730 99 0.202
regulation of cell cycle process GO:0010564 181 0.195
regulation of immune system process GO:0002682 176 0.189
regulation of cell proliferation GO:0042127 163 0.189
phosphorylation GO:0016310 294 0.177
immune response GO:0006955 246 0.173
regulation of mitotic cell cycle GO:0007346 190 0.172
vesicle mediated transport GO:0016192 381 0.171
cellular protein modification process GO:0006464 438 0.170
endocytosis GO:0006897 310 0.170
positive regulation of defense response GO:0031349 59 0.162
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.161
negative regulation of cell cycle GO:0045786 116 0.146
regulation of innate immune response GO:0045088 71 0.137
regulation of cell cycle phase transition GO:1901987 130 0.136
negative regulation of cell cycle phase transition GO:1901988 103 0.132
defense response to bacterium GO:0042742 178 0.119
establishment of localization in cell GO:0051649 402 0.118
mitotic cell cycle phase transition GO:0044772 138 0.117
mitotic g2 m transition checkpoint GO:0044818 70 0.110
protein modification by small protein conjugation or removal GO:0070647 106 0.109
defense response to gram negative bacterium GO:0050829 94 0.108
negative regulation of cell cycle process GO:0010948 109 0.107
mitotic cell cycle checkpoint GO:0007093 88 0.095
mitotic dna damage checkpoint GO:0044773 74 0.093
positive regulation of immune system process GO:0002684 68 0.089
negative regulation of mitotic cell cycle GO:0045930 109 0.089
chromosome organization GO:0051276 360 0.088
mitotic dna integrity checkpoint GO:0044774 75 0.086
antibacterial humoral response GO:0019731 44 0.085
negative regulation of cellular metabolic process GO:0031324 382 0.085
peptide metabolic process GO:0006518 80 0.085
phagocytosis GO:0006909 215 0.084
intracellular transport GO:0046907 228 0.083
negative regulation of developmental process GO:0051093 201 0.079
transcription from rna polymerase ii promoter GO:0006366 368 0.079
positive regulation of immune response GO:0050778 63 0.077
intracellular protein transport GO:0006886 104 0.072
anatomical structure homeostasis GO:0060249 97 0.068
cell proliferation GO:0008283 299 0.067
positive regulation of response to stimulus GO:0048584 323 0.066
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.064
epithelial structure maintenance GO:0010669 17 0.062
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.061
regulation of mitotic cell cycle phase transition GO:1901990 130 0.061
germarium derived egg chamber formation GO:0007293 101 0.058
regulation of protein metabolic process GO:0051246 256 0.057
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.057
chromatin organization GO:0006325 207 0.057
dorsal ventral pattern formation GO:0009953 133 0.057
positive regulation of cellular biosynthetic process GO:0031328 316 0.056
cell junction organization GO:0034330 57 0.056
synaptic vesicle localization GO:0097479 53 0.055
positive regulation of gene expression GO:0010628 290 0.055
mitotic g2 dna damage checkpoint GO:0007095 69 0.054
negative regulation of immune system process GO:0002683 50 0.053
programmed cell death GO:0012501 257 0.053
immune effector process GO:0002252 98 0.052
secretion GO:0046903 109 0.052
regulation of multicellular organismal development GO:2000026 414 0.052
negative regulation of rna biosynthetic process GO:1902679 240 0.051
protein transport GO:0015031 155 0.050
production of molecular mediator of immune response GO:0002440 46 0.050
cellular amide metabolic process GO:0043603 80 0.049
response to radiation GO:0009314 155 0.047
negative regulation of response to stimulus GO:0048585 258 0.047
organelle fission GO:0048285 340 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.046
cell cycle phase transition GO:0044770 140 0.045
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.045
segmentation GO:0035282 207 0.044
peptidyl amino acid modification GO:0018193 105 0.044
positive regulation of transcription dna templated GO:0045893 266 0.043
peptidyl tyrosine phosphorylation GO:0018108 24 0.042
cellular response to dna damage stimulus GO:0006974 223 0.042
regionalization GO:0003002 416 0.042
single organism intracellular transport GO:1902582 207 0.042
camera type eye development GO:0043010 4 0.041
dorsal ventral axis specification GO:0009950 66 0.041
histone modification GO:0016570 106 0.041
homeostatic process GO:0042592 199 0.040
positive regulation of exocytosis GO:0045921 4 0.040
cell death GO:0008219 279 0.040
cytoplasmic transport GO:0016482 130 0.039
mitochondrion organization GO:0007005 65 0.039
synaptic vesicle transport GO:0048489 50 0.038
protein complex biogenesis GO:0070271 201 0.038
protein ubiquitination GO:0016567 70 0.037
regulation of response to stress GO:0080134 200 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
negative regulation of cell communication GO:0010648 223 0.037
connective tissue development GO:0061448 3 0.036
axis specification GO:0009798 167 0.036
negative regulation of rna metabolic process GO:0051253 251 0.035
meiotic nuclear division GO:0007126 151 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.034
organic substance transport GO:0071702 257 0.034
regulation of cellular localization GO:0060341 136 0.034
establishment of synaptic vesicle localization GO:0097480 50 0.033
protein processing GO:0016485 68 0.033
negative regulation of signal transduction GO:0009968 206 0.033
tissue homeostasis GO:0001894 36 0.033
meiotic cell cycle GO:0051321 171 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.032
female meiotic division GO:0007143 70 0.032
positive regulation of cell cycle GO:0045787 43 0.031
defense response to gram positive bacterium GO:0050830 41 0.031
defense response GO:0006952 300 0.031
forebrain development GO:0030900 2 0.030
protein maturation GO:0051604 71 0.030
regulation of anatomical structure size GO:0090066 163 0.030
exocytosis GO:0006887 28 0.030
organonitrogen compound metabolic process GO:1901564 318 0.029
single organism membrane organization GO:0044802 93 0.029
cellular response to extracellular stimulus GO:0031668 64 0.028
cellular response to chemical stimulus GO:0070887 199 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
response to oxygen containing compound GO:1901700 200 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.027
regulation of organelle organization GO:0033043 196 0.027
regulation of immune effector process GO:0002697 52 0.027
protein modification by small protein conjugation GO:0032446 79 0.027
multicellular organismal aging GO:0010259 140 0.026
positive regulation of innate immune response GO:0045089 38 0.026
protein phosphorylation GO:0006468 169 0.026
regulation of transport GO:0051049 181 0.026
regulation of response to biotic stimulus GO:0002831 63 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
regulation of intracellular signal transduction GO:1902531 236 0.025
mitotic cell cycle embryonic GO:0045448 38 0.025
establishment of protein localization GO:0045184 163 0.025
glutathione metabolic process GO:0006749 37 0.025
dna damage checkpoint GO:0000077 78 0.025
axonogenesis GO:0007409 290 0.025
organelle localization GO:0051640 148 0.025
secretion by cell GO:0032940 101 0.024
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.024
death GO:0016265 284 0.024
g2 dna damage checkpoint GO:0031572 69 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
dna integrity checkpoint GO:0031570 81 0.024
cell cell junction organization GO:0045216 55 0.024
regulation of humoral immune response GO:0002920 51 0.024
organelle fusion GO:0048284 46 0.024
multicellular organismal homeostasis GO:0048871 41 0.023
establishment of vesicle localization GO:0051650 51 0.023
melanization defense response GO:0035006 45 0.023
spinal cord development GO:0021510 1 0.023
positive regulation of transport GO:0051050 92 0.023
chromosome segregation GO:0007059 157 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
regulation of protein transport GO:0051223 57 0.022
proteolysis GO:0006508 192 0.022
positive regulation of rna metabolic process GO:0051254 271 0.021
regulation of neurogenesis GO:0050767 158 0.021
negative regulation of programmed cell death GO:0043069 72 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
regulation of cell division GO:0051302 72 0.021
regulation of dna metabolic process GO:0051052 34 0.020
negative regulation of protein metabolic process GO:0051248 85 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
covalent chromatin modification GO:0016569 106 0.020
response to wounding GO:0009611 94 0.020
body morphogenesis GO:0010171 2 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
regulation of synapse organization GO:0050807 110 0.020
protein localization GO:0008104 284 0.019
response to starvation GO:0042594 97 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
cell cycle checkpoint GO:0000075 95 0.019
negative regulation of growth GO:0045926 84 0.019
spindle organization GO:0007051 253 0.019
cellular catabolic process GO:0044248 372 0.019
response to fungus GO:0009620 50 0.019
cell cycle arrest GO:0007050 4 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
chromatin modification GO:0016568 147 0.018
positive regulation of developmental process GO:0051094 143 0.018
negative regulation of signaling GO:0023057 219 0.018
establishment of organelle localization GO:0051656 122 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
regulation of multi organism process GO:0043900 131 0.018
jak stat cascade GO:0007259 49 0.017
protein modification by small protein removal GO:0070646 28 0.017
intracellular signal transduction GO:0035556 300 0.017
rna processing GO:0006396 147 0.017
response to abiotic stimulus GO:0009628 341 0.017
larval development GO:0002164 104 0.017
regulation of intracellular transport GO:0032386 64 0.017
regulation of intracellular protein transport GO:0033157 46 0.017
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.017
regulation of double strand break repair GO:2000779 3 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
membrane organization GO:0061024 112 0.017
regulation of cellular amide metabolic process GO:0034248 39 0.017
proteasomal protein catabolic process GO:0010498 59 0.016
central nervous system development GO:0007417 201 0.016
phenol containing compound metabolic process GO:0018958 57 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
regulation of antimicrobial humoral response GO:0002759 50 0.016
regulation of tube size GO:0035150 46 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
vesicle localization GO:0051648 55 0.016
multi organism behavior GO:0051705 175 0.016
nuclear export GO:0051168 24 0.016
regulation of synapse assembly GO:0051963 94 0.016
single organism cellular localization GO:1902580 180 0.015
cellular response to organic substance GO:0071310 132 0.015
apoptotic process GO:0006915 159 0.015
regulation of protein stability GO:0031647 43 0.015
cellular macromolecule localization GO:0070727 220 0.015
cellular protein catabolic process GO:0044257 83 0.015
cell adhesion GO:0007155 136 0.015
regulation of catabolic process GO:0009894 170 0.015
regulation of dna recombination GO:0000018 4 0.015
microtubule organizing center organization GO:0031023 168 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
positive regulation of cell migration GO:0030335 2 0.015
regulation of tube size open tracheal system GO:0035151 43 0.015
tube development GO:0035295 244 0.015
response to light stimulus GO:0009416 124 0.015
macromolecule catabolic process GO:0009057 161 0.015
lipid storage GO:0019915 38 0.015
peptidyl threonine phosphorylation GO:0018107 2 0.015
activation of innate immune response GO:0002218 4 0.015
organic substance catabolic process GO:1901575 308 0.015
regulation of protein localization GO:0032880 76 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
catabolic process GO:0009056 409 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
regulation of cell cycle g1 s phase transition GO:1902806 23 0.014
negative regulation of cell death GO:0060548 81 0.014
cellular component maintenance GO:0043954 23 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
telencephalon development GO:0021537 2 0.014
tissue migration GO:0090130 155 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
cellular protein complex assembly GO:0043623 71 0.014
macromolecular complex assembly GO:0065003 256 0.014
synaptic vesicle recycling GO:0036465 28 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
response to organophosphorus GO:0046683 2 0.013
negative regulation of chromosome segregation GO:0051985 14 0.013
developmental maturation GO:0021700 172 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.013
encapsulation of foreign target GO:0035010 38 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
antimicrobial peptide production GO:0002775 46 0.013
protein targeting GO:0006605 64 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
ion transport GO:0006811 145 0.013
reproductive structure development GO:0048608 74 0.013
leg disc morphogenesis GO:0007478 80 0.013
bmp signaling pathway GO:0030509 27 0.013
positive regulation of protein catabolic process GO:0045732 34 0.013
response to bacterium GO:0009617 198 0.013
cell type specific apoptotic process GO:0097285 38 0.013
hindbrain development GO:0030902 2 0.013
regulation of localization GO:0032879 275 0.013
single organism behavior GO:0044708 391 0.013
notch signaling pathway GO:0007219 120 0.012
appendage development GO:0048736 401 0.012
pigment metabolic process GO:0042440 84 0.012
eye antennal disc development GO:0035214 60 0.012
chemotaxis GO:0006935 249 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
positive regulation of cell communication GO:0010647 250 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
axon development GO:0061564 297 0.012
wound healing GO:0042060 75 0.012
peptidyl tyrosine modification GO:0018212 24 0.012
acetylcholine catabolic process GO:0006581 1 0.012
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.012
peptidyl threonine modification GO:0018210 3 0.012
spinal cord patterning GO:0021511 1 0.011
nuclear division GO:0000280 332 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cellular response to ionizing radiation GO:0071479 15 0.011
regulation of nurse cell apoptotic process GO:0045477 9 0.011
epithelium migration GO:0090132 148 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
rna 3 end processing GO:0031123 45 0.011
meiotic chromosome segregation GO:0045132 59 0.011
growth GO:0040007 359 0.011
positive regulation of intracellular protein transport GO:0090316 30 0.011
peripheral nervous system development GO:0007422 52 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
biological adhesion GO:0022610 138 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
nuclear transport GO:0051169 72 0.011
spermatogenesis GO:0007283 200 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
response to endogenous stimulus GO:0009719 119 0.011
chaeta development GO:0022416 97 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
vesicle organization GO:0016050 44 0.011
cellular pigmentation GO:0033059 12 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
dorsal appendage formation GO:0046843 47 0.011
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.011
immune response activating signal transduction GO:0002757 2 0.010
response to glucose GO:0009749 2 0.010
regulation of programmed cell death GO:0043067 152 0.010
response to organic substance GO:0010033 284 0.010
positive regulation of cell motility GO:2000147 3 0.010
positive regulation of signaling GO:0023056 243 0.010
regulation of establishment of protein localization GO:0070201 61 0.010
spindle assembly GO:0051225 80 0.010
locomotory behavior GO:0007626 176 0.010
melanin metabolic process GO:0006582 47 0.010
cell migration GO:0016477 238 0.010
nitrogen compound transport GO:0071705 85 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010

rev7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.015
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014