Drosophila melanogaster

25 known processes

form3 (Dmel_CG33556)

formin 3

(Aliases: ah1644,CG32384,CG8633,Form3,Dmel\CG33556,formin/DIA-like,CG14824,CG33556,CG18138,INF2)

form3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of tube architecture open tracheal system GO:0035152 68 0.916
open tracheal system development GO:0007424 204 0.882
respiratory system development GO:0060541 213 0.836
axon guidance GO:0007411 233 0.829
chemotaxis GO:0006935 249 0.763
taxis GO:0042330 304 0.639
regulation of tube size open tracheal system GO:0035151 43 0.568
regulation of tube length open tracheal system GO:0035159 24 0.524
axon development GO:0061564 297 0.480
regulation of tube diameter open tracheal system GO:0035158 11 0.367
epithelial cell differentiation GO:0030855 322 0.360
neuron projection guidance GO:0097485 241 0.349
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.349
axonogenesis GO:0007409 290 0.283
gliogenesis GO:0042063 80 0.249
cell proliferation GO:0008283 299 0.196
cell motility GO:0048870 251 0.189
growth GO:0040007 359 0.167
nucleotide metabolic process GO:0009117 161 0.164
regulation of axon extension involved in axon guidance GO:0048841 4 0.163
developmental growth GO:0048589 280 0.162
regulation of cell differentiation GO:0045595 302 0.159
photoreceptor cell axon guidance GO:0072499 23 0.155
glial cell migration GO:0008347 31 0.142
axon midline choice point recognition GO:0016199 26 0.140
regulation of multicellular organismal development GO:2000026 414 0.140
axon choice point recognition GO:0016198 26 0.134
positive regulation of cellular biosynthetic process GO:0031328 316 0.131
actin cytoskeleton organization GO:0030036 206 0.127
motor neuron axon guidance GO:0008045 58 0.126
positive regulation of transcription dna templated GO:0045893 266 0.118
forebrain development GO:0030900 2 0.117
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.116
programmed cell death GO:0012501 257 0.113
regulation of immune system process GO:0002682 176 0.113
epithelial cell migration open tracheal system GO:0007427 32 0.108
regulation of anatomical structure size GO:0090066 163 0.108
sensory organ morphogenesis GO:0090596 260 0.106
cell recognition GO:0008037 102 0.100
tube development GO:0035295 244 0.098
cell death GO:0008219 279 0.096
cell cell junction assembly GO:0007043 38 0.094
immune system process GO:0002376 347 0.088
regulation of cell development GO:0060284 215 0.087
establishment of blood brain barrier GO:0060856 16 0.084
tissue morphogenesis GO:0048729 297 0.080
localization of cell GO:0051674 257 0.079
intracellular signal transduction GO:0035556 300 0.079
organophosphate metabolic process GO:0019637 195 0.077
regulation of tube size GO:0035150 46 0.076
response to biotic stimulus GO:0009607 294 0.076
g protein coupled receptor signaling pathway GO:0007186 136 0.073
organonitrogen compound metabolic process GO:1901564 318 0.072
appendage morphogenesis GO:0035107 397 0.069
spiracle morphogenesis open tracheal system GO:0035277 22 0.068
axon extension involved in axon guidance GO:0048846 10 0.068
cell migration GO:0016477 238 0.067
extrinsic apoptotic signaling pathway GO:0097191 1 0.066
salivary gland morphogenesis GO:0007435 145 0.066
columnar cuboidal epithelial cell development GO:0002066 249 0.065
negative regulation of cell communication GO:0010648 223 0.065
tracheal outgrowth open tracheal system GO:0007426 18 0.064
regulation of tube diameter GO:0035296 14 0.063
dna metabolic process GO:0006259 227 0.063
positive regulation of nucleic acid templated transcription GO:1903508 266 0.063
regulation of nervous system development GO:0051960 248 0.062
regulation of phosphorus metabolic process GO:0051174 210 0.061
oocyte development GO:0048599 124 0.060
tube morphogenesis GO:0035239 191 0.059
protein complex assembly GO:0006461 200 0.059
response to organic substance GO:0010033 284 0.059
imaginal disc derived appendage development GO:0048737 399 0.059
regulation of intracellular signal transduction GO:1902531 236 0.059
catabolic process GO:0009056 409 0.058
positive regulation of signaling GO:0023056 243 0.057
positive regulation of secretion by cell GO:1903532 20 0.055
positive regulation of signal transduction GO:0009967 223 0.055
signal transduction by phosphorylation GO:0023014 107 0.054
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
post embryonic appendage morphogenesis GO:0035120 385 0.051
regulation of cell proliferation GO:0042127 163 0.051
positive regulation of axonogenesis GO:0050772 2 0.051
morphogenesis of an epithelium GO:0002009 276 0.051
cellular macromolecular complex assembly GO:0034622 153 0.050
gland development GO:0048732 191 0.049
apoptotic process GO:0006915 159 0.049
eye morphogenesis GO:0048592 260 0.048
positive regulation of phosphorus metabolic process GO:0010562 139 0.048
negative regulation of signal transduction GO:0009968 206 0.048
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.048
r7 cell differentiation GO:0045466 43 0.048
imaginal disc derived appendage morphogenesis GO:0035114 395 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.047
death GO:0016265 284 0.045
compound eye photoreceptor cell differentiation GO:0001751 140 0.045
cell maturation GO:0048469 144 0.045
response to abiotic stimulus GO:0009628 341 0.045
branching involved in open tracheal system development GO:0060446 45 0.045
carbohydrate derivative metabolic process GO:1901135 217 0.045
ameboidal type cell migration GO:0001667 151 0.044
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.044
response to radiation GO:0009314 155 0.044
trachea development GO:0060438 29 0.044
wing disc morphogenesis GO:0007472 344 0.043
developmental growth involved in morphogenesis GO:0060560 65 0.043
positive regulation of gene expression GO:0010628 290 0.043
telencephalon development GO:0021537 2 0.042
regulation of cellular ketone metabolic process GO:0010565 3 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
compound eye morphogenesis GO:0001745 249 0.042
small gtpase mediated signal transduction GO:0007264 88 0.042
carbohydrate derivative biosynthetic process GO:1901137 85 0.041
protein modification process GO:0036211 438 0.040
associative learning GO:0008306 65 0.040
neuron fate commitment GO:0048663 50 0.039
brain development GO:0007420 120 0.039
cell junction organization GO:0034330 57 0.039
dorsal trunk growth open tracheal system GO:0035001 7 0.039
positive regulation of rna metabolic process GO:0051254 271 0.038
regulation of immune response GO:0050776 118 0.038
striated muscle cell differentiation GO:0051146 90 0.038
regulation of localization GO:0032879 275 0.037
protein complex biogenesis GO:0070271 201 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
macromolecule catabolic process GO:0009057 161 0.037
regulation of mapk cascade GO:0043408 92 0.037
protein phosphorylation GO:0006468 169 0.036
carbohydrate derivative catabolic process GO:1901136 118 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.036
membrane organization GO:0061024 112 0.036
regulation of cell morphogenesis GO:0022604 163 0.036
response to external biotic stimulus GO:0043207 293 0.035
regulation of behavior GO:0050795 75 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
cuticle development GO:0042335 86 0.035
regulation of microtubule based process GO:0032886 49 0.035
cell projection assembly GO:0030031 94 0.034
regulation of secretion by cell GO:1903530 39 0.034
cellular protein modification process GO:0006464 438 0.034
positive regulation of immune system process GO:0002684 68 0.034
nucleobase containing small molecule metabolic process GO:0055086 174 0.033
cell adhesion GO:0007155 136 0.033
appendage development GO:0048736 401 0.033
actin filament based process GO:0030029 220 0.033
genital disc development GO:0035215 44 0.033
metal ion transport GO:0030001 74 0.032
ventral cord development GO:0007419 16 0.032
chitin based cuticle development GO:0040003 49 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
digestive tract development GO:0048565 149 0.031
negative regulation of cell proliferation GO:0008285 69 0.031
regulation of cell projection organization GO:0031344 92 0.031
single organism behavior GO:0044708 391 0.031
developmental induction GO:0031128 3 0.030
negative regulation of signaling GO:0023057 219 0.030
neuron recognition GO:0008038 101 0.030
septate junction assembly GO:0019991 26 0.029
adult behavior GO:0030534 137 0.029
lateral inhibition GO:0046331 206 0.029
dorsal ventral axon guidance GO:0033563 2 0.028
olfactory bulb axon guidance GO:0071678 3 0.028
developmental programmed cell death GO:0010623 138 0.028
cation transport GO:0006812 110 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
innate immune response GO:0045087 144 0.027
oocyte differentiation GO:0009994 145 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.026
immune system development GO:0002520 57 0.026
organic substance catabolic process GO:1901575 308 0.026
defense response to other organism GO:0098542 225 0.026
organonitrogen compound catabolic process GO:1901565 128 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
organic substance transport GO:0071702 257 0.025
secretion GO:0046903 109 0.025
response to lipopolysaccharide GO:0032496 4 0.025
regulation of phosphorylation GO:0042325 147 0.025
response to other organism GO:0051707 293 0.025
hemopoiesis GO:0030097 46 0.025
urogenital system development GO:0001655 72 0.024
establishment of localization in cell GO:0051649 402 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
regulation of neuron differentiation GO:0045664 103 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
dendrite morphogenesis GO:0048813 199 0.024
camera type eye development GO:0043010 4 0.024
positive regulation of cell communication GO:0010647 250 0.024
developmental maturation GO:0021700 172 0.023
positive regulation of cellular component biogenesis GO:0044089 80 0.023
endocytosis GO:0006897 310 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
regulation of protein complex disassembly GO:0043244 29 0.023
regulation of cell substrate adhesion GO:0010810 2 0.023
epithelial cell type specification open tracheal system GO:0035153 11 0.023
reproductive structure development GO:0048608 74 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
neuron projection extension GO:1990138 32 0.022
mapk cascade GO:0000165 107 0.022
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.022
kidney development GO:0001822 3 0.022
ras protein signal transduction GO:0007265 88 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
exocrine system development GO:0035272 162 0.022
dendrite development GO:0016358 204 0.022
regulation of response to stress GO:0080134 200 0.022
organelle fission GO:0048285 340 0.022
kidney epithelium development GO:0072073 3 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
regulation of transport GO:0051049 181 0.021
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
heart development GO:0007507 82 0.021
tissue migration GO:0090130 155 0.021
epithelial cell development GO:0002064 274 0.021
salivary gland development GO:0007431 162 0.021
mesodermal cell migration GO:0008078 7 0.021
single organism biosynthetic process GO:0044711 206 0.020
digestive system development GO:0055123 149 0.020
golgi vesicle transport GO:0048193 27 0.020
oxoacid metabolic process GO:0043436 103 0.020
negative regulation of apoptotic process GO:0043066 63 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
phosphorylation GO:0016310 294 0.020
memory GO:0007613 94 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.019
imaginal disc derived wing hair organization GO:0035317 45 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
male mating behavior GO:0060179 70 0.019
regulation of molecular function GO:0065009 217 0.019
vesicle mediated transport GO:0016192 381 0.019
dephosphorylation GO:0016311 51 0.019
epithelium migration GO:0090132 148 0.019
small molecule metabolic process GO:0044281 305 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
compound eye photoreceptor development GO:0042051 78 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
skeletal muscle fiber development GO:0048741 3 0.018
negative regulation of multi organism process GO:0043901 29 0.018
protein localization GO:0008104 284 0.018
macromolecular complex assembly GO:0065003 256 0.018
defense response GO:0006952 300 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.018
developmental cell growth GO:0048588 52 0.018
morphogenesis of follicular epithelium GO:0016333 36 0.018
anatomical structure homeostasis GO:0060249 97 0.017
regulation of cell death GO:0010941 173 0.017
non sensory hair organization GO:0035316 47 0.017
cell cell junction organization GO:0045216 55 0.017
regionalization GO:0003002 416 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
amino sugar metabolic process GO:0006040 10 0.017
regulation of programmed cell death GO:0043067 152 0.017
eye development GO:0001654 323 0.017
chromosome segregation GO:0007059 157 0.017
regulation of protein serine threonine kinase activity GO:0071900 25 0.016
eye photoreceptor cell fate commitment GO:0042706 37 0.016
positive regulation of axon extension GO:0045773 2 0.016
ovarian follicle cell migration GO:0007297 121 0.016
regulation of apoptotic process GO:0042981 130 0.016
central nervous system development GO:0007417 201 0.016
axon extension GO:0048675 32 0.016
determination of ventral identity GO:0048264 1 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
organic hydroxy compound biosynthetic process GO:1901617 21 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
protein catabolic process GO:0030163 101 0.016
dna packaging GO:0006323 91 0.015
regulation of catalytic activity GO:0050790 185 0.015
branch fusion open tracheal system GO:0035147 17 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
regulation of chemotaxis GO:0050920 12 0.015
cell migration involved in gastrulation GO:0042074 9 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
synaptic target recognition GO:0008039 45 0.015
male meiosis chromosome segregation GO:0007060 10 0.015
regulation of cell growth GO:0001558 43 0.015
amino sugar catabolic process GO:0046348 3 0.015
cellular response to oxidative stress GO:0034599 28 0.015
regulation of axon guidance GO:1902667 10 0.015
secretion by cell GO:0032940 101 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
endomembrane system organization GO:0010256 119 0.014
mesoderm development GO:0007498 78 0.014
lamellipodium organization GO:0097581 21 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
homeostatic process GO:0042592 199 0.014
aminoglycan metabolic process GO:0006022 18 0.014
response to alcohol GO:0097305 95 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
amine metabolic process GO:0009308 12 0.014
response to bacterium GO:0009617 198 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
single organism intracellular transport GO:1902582 207 0.014
protein transport GO:0015031 155 0.014
negative regulation of immune system process GO:0002683 50 0.014
epidermal cell differentiation GO:0009913 51 0.014
convergent extension GO:0060026 2 0.014
positive regulation of cellular component organization GO:0051130 156 0.014
actin filament organization GO:0007015 126 0.014
epithelial cell migration GO:0010631 148 0.014
organic hydroxy compound metabolic process GO:1901615 83 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of neurogenesis GO:0050767 158 0.014
protein depolymerization GO:0051261 31 0.014
positive regulation of growth GO:0045927 75 0.014
central nervous system projection neuron axonogenesis GO:0021952 6 0.013
formation of anatomical boundary GO:0048859 37 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
positive regulation of nervous system development GO:0051962 69 0.013
regulation of cellular localization GO:0060341 136 0.013
determination of dorsal ventral asymmetry GO:0048262 3 0.013
imaginal disc growth GO:0007446 37 0.013
regulation of oocyte development GO:0060281 27 0.013
gland morphogenesis GO:0022612 145 0.013
renal filtration cell differentiation GO:0061318 12 0.013
regulation of protein kinase activity GO:0045859 51 0.013
positive chemotaxis GO:0050918 4 0.013
mesodermal cell fate specification GO:0007501 2 0.013
positive regulation of cell development GO:0010720 61 0.013
cellular response to organic substance GO:0071310 132 0.013
mitotic spindle organization GO:0007052 220 0.013
establishment of protein localization GO:0045184 163 0.013
phosphatidylinositol mediated signaling GO:0048015 4 0.013
skin development GO:0043588 65 0.013
embryonic morphogenesis GO:0048598 206 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
regulation of protein phosphorylation GO:0001932 64 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.012
glycoprotein metabolic process GO:0009100 41 0.012
hindbrain development GO:0030902 2 0.012
regulation of protein secretion GO:0050708 13 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
regulation of transferase activity GO:0051338 58 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
response to ionizing radiation GO:0010212 32 0.012
negative regulation of cytoskeleton organization GO:0051494 30 0.012
oocyte maturation GO:0001556 3 0.012
visual learning GO:0008542 4 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
regulation of growth GO:0040008 233 0.012
single organism cellular localization GO:1902580 180 0.012
defense response to bacterium GO:0042742 178 0.012
rho protein signal transduction GO:0007266 14 0.012
positive regulation of neurogenesis GO:0050769 41 0.012
response to oxygen containing compound GO:1901700 200 0.012
proteolysis GO:0006508 192 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.012
protein maturation GO:0051604 71 0.012
negative regulation of cell development GO:0010721 62 0.012
cellular protein complex disassembly GO:0043624 35 0.012
retina development in camera type eye GO:0060041 4 0.011
nucleotide biosynthetic process GO:0009165 34 0.011
eye photoreceptor cell development GO:0042462 81 0.011
cytoplasm organization GO:0007028 64 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
positive regulation of innate immune response GO:0045089 38 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
negative regulation of organelle organization GO:0010639 56 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of secretion GO:0051046 44 0.011
cell growth GO:0016049 108 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
muscle structure development GO:0061061 224 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
response to paraquat GO:1901562 4 0.011
myotube cell development GO:0014904 3 0.011
metal ion homeostasis GO:0055065 44 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
positive regulation of immune response GO:0050778 63 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
hindgut development GO:0061525 58 0.011
terminal branching open tracheal system GO:0007430 17 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
response to ethanol GO:0045471 59 0.011
cardiovascular system development GO:0072358 82 0.011
positive regulation of molecular function GO:0044093 136 0.011
cognition GO:0050890 141 0.011
regulation of protein metabolic process GO:0051246 256 0.010
regulation of map kinase activity GO:0043405 17 0.010
compound eye development GO:0048749 307 0.010
negative regulation of developmental growth GO:0048640 64 0.010
hair cell differentiation GO:0035315 47 0.010
regulation of cellular component size GO:0032535 98 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.010
adult locomotory behavior GO:0008344 76 0.010
body morphogenesis GO:0010171 2 0.010
response to organophosphorus GO:0046683 2 0.010
apical junction assembly GO:0043297 32 0.010
amino sugar biosynthetic process GO:0046349 5 0.010
positive regulation of ras protein signal transduction GO:0046579 43 0.010
central complex development GO:0048036 9 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
hindgut morphogenesis GO:0007442 58 0.010
negative regulation of gene expression GO:0010629 387 0.010
learning GO:0007612 75 0.010
negative regulation of axon extension GO:0030517 3 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
axis specification GO:0009798 167 0.010
neuroblast development GO:0014019 13 0.010
response to endogenous stimulus GO:0009719 119 0.010

form3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.152
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
nervous system disease DOID:863 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.011
heart conduction disease DOID:10273 0 0.010
cardiovascular system disease DOID:1287 0 0.010