Drosophila melanogaster

0 known processes

Actn3 (Dmel_CG8953)

alpha actinin 3

(Aliases: dabp,acta-3,ORF1,CG8953,Dmel\CG8953)

Actn3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.044
carboxylic acid metabolic process GO:0019752 92 0.039
protein modification process GO:0036211 438 0.036
organic acid metabolic process GO:0006082 103 0.035
regulation of localization GO:0032879 275 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
intracellular transport GO:0046907 228 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.030
imaginal disc derived appendage development GO:0048737 399 0.030
establishment of localization in cell GO:0051649 402 0.029
organic substance transport GO:0071702 257 0.029
positive regulation of cell communication GO:0010647 250 0.029
regulation of phosphorus metabolic process GO:0051174 210 0.028
vesicle mediated transport GO:0016192 381 0.027
response to biotic stimulus GO:0009607 294 0.027
organic substance catabolic process GO:1901575 308 0.026
defense response GO:0006952 300 0.026
organelle assembly GO:0070925 198 0.026
response to external biotic stimulus GO:0043207 293 0.026
appendage morphogenesis GO:0035107 397 0.025
positive regulation of signaling GO:0023056 243 0.025
oxoacid metabolic process GO:0043436 103 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
wing disc morphogenesis GO:0007472 344 0.024
appendage development GO:0048736 401 0.024
negative regulation of signal transduction GO:0009968 206 0.024
cellular catabolic process GO:0044248 372 0.024
catabolic process GO:0009056 409 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
camera type eye development GO:0043010 4 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
kidney development GO:0001822 3 0.022
cellular protein modification process GO:0006464 438 0.022
ion transmembrane transport GO:0034220 122 0.022
homeostatic process GO:0042592 199 0.022
spermatid development GO:0007286 98 0.022
response to abiotic stimulus GO:0009628 341 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
negative regulation of cell communication GO:0010648 223 0.021
immune response GO:0006955 246 0.021
response to lipopolysaccharide GO:0032496 4 0.021
response to other organism GO:0051707 293 0.021
phosphorylation GO:0016310 294 0.021
regulation of immune response GO:0050776 118 0.020
defense response to other organism GO:0098542 225 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
positive regulation of signal transduction GO:0009967 223 0.018
single organism biosynthetic process GO:0044711 206 0.018
male gamete generation GO:0048232 201 0.018
regulation of cell cycle GO:0051726 291 0.018
regulation of multicellular organismal development GO:2000026 414 0.017
positive regulation of cell motility GO:2000147 3 0.017
regulation of transport GO:0051049 181 0.017
forebrain development GO:0030900 2 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
secondary metabolic process GO:0019748 75 0.017
endocytosis GO:0006897 310 0.017
death GO:0016265 284 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
antimicrobial humoral response GO:0019730 99 0.017
response to organophosphorus GO:0046683 2 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
body morphogenesis GO:0010171 2 0.016
lateral inhibition GO:0046331 206 0.016
telencephalon development GO:0021537 2 0.016
single organism intracellular transport GO:1902582 207 0.016
spermatid differentiation GO:0048515 114 0.016
endomembrane system organization GO:0010256 119 0.016
intracellular signal transduction GO:0035556 300 0.016
regulation of molecular function GO:0065009 217 0.016
regulation of catalytic activity GO:0050790 185 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
response to bacterium GO:0009617 198 0.016
retina development in camera type eye GO:0060041 4 0.016
protein phosphorylation GO:0006468 169 0.016
immune system process GO:0002376 347 0.015
cell division GO:0051301 248 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
negative regulation of signaling GO:0023057 219 0.015
cation transmembrane transport GO:0098655 88 0.015
mitotic nuclear division GO:0007067 213 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
growth GO:0040007 359 0.015
cell projection assembly GO:0030031 94 0.015
response to hexose GO:0009746 3 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
aromatic compound catabolic process GO:0019439 166 0.015
negative regulation of gene expression GO:0010629 387 0.015
spermatogenesis GO:0007283 200 0.015
regulation of cell differentiation GO:0045595 302 0.015
regulation of immune system process GO:0002682 176 0.014
mating GO:0007618 120 0.014
phagocytosis GO:0006909 215 0.014
heterocycle catabolic process GO:0046700 166 0.014
chromosome organization GO:0051276 360 0.014
regulation of protein metabolic process GO:0051246 256 0.014
golgi organization GO:0007030 66 0.014
cell proliferation GO:0008283 299 0.014
response to organic substance GO:0010033 284 0.014
response to oxygen containing compound GO:1901700 200 0.014
regionalization GO:0003002 416 0.014
cell motility GO:0048870 251 0.014
purine nucleotide metabolic process GO:0006163 146 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
regulation of response to stress GO:0080134 200 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
programmed cell death GO:0012501 257 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
ion transport GO:0006811 145 0.013
cell death GO:0008219 279 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
dendrite development GO:0016358 204 0.013
chromosome segregation GO:0007059 157 0.013
dendrite morphogenesis GO:0048813 199 0.013
central nervous system development GO:0007417 201 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
eye development GO:0001654 323 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of multi organism process GO:0043900 131 0.013
glycosyl compound metabolic process GO:1901657 127 0.012
muscle organ development GO:0007517 127 0.012
amine metabolic process GO:0009308 12 0.012
compound eye development GO:0048749 307 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
camera type eye morphogenesis GO:0048593 2 0.012
purine containing compound metabolic process GO:0072521 155 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
mitotic spindle organization GO:0007052 220 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
protein localization GO:0008104 284 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
tissue morphogenesis GO:0048729 297 0.012
lipid metabolic process GO:0006629 121 0.012
eye morphogenesis GO:0048592 260 0.012
regulation of catabolic process GO:0009894 170 0.012
macromolecular complex assembly GO:0065003 256 0.012
somatic muscle development GO:0007525 66 0.012
humoral immune response GO:0006959 117 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
negative regulation of developmental process GO:0051093 201 0.011
response to glucose GO:0009749 2 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
spindle organization GO:0007051 253 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular amine metabolic process GO:0044106 12 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
regulation of cellular localization GO:0060341 136 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
response to wounding GO:0009611 94 0.011
multi organism reproductive behavior GO:0044705 121 0.011
actin cytoskeleton organization GO:0030036 206 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of organelle organization GO:0033043 196 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
ras protein signal transduction GO:0007265 88 0.011
cellular ketone metabolic process GO:0042180 24 0.011
nucleoside metabolic process GO:0009116 127 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
regulation of hydrolase activity GO:0051336 97 0.011
organelle fission GO:0048285 340 0.011
response to monosaccharide GO:0034284 4 0.011
cilium assembly GO:0042384 38 0.011
macromolecule catabolic process GO:0009057 161 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
nucleoside catabolic process GO:0009164 112 0.011
neurological system process GO:0050877 358 0.011
regulation of phosphorylation GO:0042325 147 0.010
protein transport GO:0015031 155 0.010
response to nutrient levels GO:0031667 114 0.010
wnt signaling pathway GO:0016055 98 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
defense response to bacterium GO:0042742 178 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
regulation of cell cycle process GO:0010564 181 0.010
cellularization GO:0007349 90 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
embryonic morphogenesis GO:0048598 206 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
cell adhesion GO:0007155 136 0.010
positive regulation of transport GO:0051050 92 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
segmentation GO:0035282 207 0.010
notch signaling pathway GO:0007219 120 0.010
microtubule based movement GO:0007018 51 0.010
transmembrane transport GO:0055085 139 0.010
cilium organization GO:0044782 41 0.010
acetate ester metabolic process GO:1900619 2 0.010
regulation of response to external stimulus GO:0032101 115 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
nitrogen compound transport GO:0071705 85 0.010
taxis GO:0042330 304 0.010
epithelial cell differentiation GO:0030855 322 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
rna processing GO:0006396 147 0.010
long chain fatty acid metabolic process GO:0001676 3 0.010

Actn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.013
diabetes mellitus DOID:9351 0 0.012
disease of metabolism DOID:0014667 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.012
glucose metabolism disease DOID:4194 0 0.012
acquired metabolic disease DOID:0060158 0 0.012