Drosophila melanogaster

0 known processes

Spn43Ad (Dmel_CG1859)

Serpin 43Ad

(Aliases: Dmel\CG1859,CG1859)

Spn43Ad biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wing disc morphogenesis GO:0007472 344 0.051
organonitrogen compound metabolic process GO:1901564 318 0.051
small molecule metabolic process GO:0044281 305 0.050
post embryonic appendage morphogenesis GO:0035120 385 0.049
imaginal disc derived appendage development GO:0048737 399 0.046
immune system process GO:0002376 347 0.042
response to other organism GO:0051707 293 0.041
appendage development GO:0048736 401 0.040
compound eye development GO:0048749 307 0.039
carboxylic acid metabolic process GO:0019752 92 0.039
imaginal disc derived wing morphogenesis GO:0007476 337 0.039
response to external biotic stimulus GO:0043207 293 0.038
oxoacid metabolic process GO:0043436 103 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
organic acid metabolic process GO:0006082 103 0.036
appendage morphogenesis GO:0035107 397 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
response to biotic stimulus GO:0009607 294 0.034
catabolic process GO:0009056 409 0.033
regulation of multicellular organismal development GO:2000026 414 0.031
vesicle mediated transport GO:0016192 381 0.031
organic substance catabolic process GO:1901575 308 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
protein modification process GO:0036211 438 0.030
reproductive behavior GO:0019098 122 0.030
cellular catabolic process GO:0044248 372 0.030
regulation of localization GO:0032879 275 0.030
compound eye morphogenesis GO:0001745 249 0.029
single organism biosynthetic process GO:0044711 206 0.029
endocytosis GO:0006897 310 0.029
cell proliferation GO:0008283 299 0.029
response to abiotic stimulus GO:0009628 341 0.029
establishment of localization in cell GO:0051649 402 0.029
developmental growth GO:0048589 280 0.029
organic substance transport GO:0071702 257 0.027
response to bacterium GO:0009617 198 0.027
cholesterol homeostasis GO:0042632 3 0.027
neurological system process GO:0050877 358 0.027
eye development GO:0001654 323 0.027
body morphogenesis GO:0010171 2 0.027
negative regulation of response to stimulus GO:0048585 258 0.026
eye morphogenesis GO:0048592 260 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
sensory organ morphogenesis GO:0090596 260 0.026
response to organic substance GO:0010033 284 0.026
negative regulation of cell communication GO:0010648 223 0.025
mating GO:0007618 120 0.025
single organism behavior GO:0044708 391 0.025
intracellular signal transduction GO:0035556 300 0.025
growth GO:0040007 359 0.025
cellular protein modification process GO:0006464 438 0.025
regulation of immune system process GO:0002682 176 0.024
forebrain development GO:0030900 2 0.024
positive regulation of signaling GO:0023056 243 0.024
multi organism behavior GO:0051705 175 0.024
single organism catabolic process GO:0044712 228 0.024
defense response GO:0006952 300 0.024
phagocytosis GO:0006909 215 0.024
organophosphate metabolic process GO:0019637 195 0.024
positive regulation of cell communication GO:0010647 250 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
negative regulation of gene expression GO:0010629 387 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
anion homeostasis GO:0055081 3 0.023
sterol homeostasis GO:0055092 4 0.023
negative regulation of signal transduction GO:0009968 206 0.023
mating behavior GO:0007617 106 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
defense response to bacterium GO:0042742 178 0.022
multi organism reproductive behavior GO:0044705 121 0.022
proteolysis GO:0006508 192 0.022
regulation of transport GO:0051049 181 0.022
response to oxygen containing compound GO:1901700 200 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
defense response to other organism GO:0098542 225 0.022
multi multicellular organism process GO:0044706 123 0.022
cellular amino acid metabolic process GO:0006520 61 0.021
regulation of multi organism process GO:0043900 131 0.021
neutral lipid biosynthetic process GO:0046460 2 0.021
lipid metabolic process GO:0006629 121 0.021
cellular lipid metabolic process GO:0044255 83 0.021
death GO:0016265 284 0.021
positive regulation of cell migration GO:0030335 2 0.021
protein localization GO:0008104 284 0.021
kidney development GO:0001822 3 0.021
cell death GO:0008219 279 0.021
tissue morphogenesis GO:0048729 297 0.021
immune response GO:0006955 246 0.021
negative regulation of signaling GO:0023057 219 0.020
regionalization GO:0003002 416 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
camera type eye development GO:0043010 4 0.020
immune response activating signal transduction GO:0002757 2 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
positive regulation of signal transduction GO:0009967 223 0.020
multicellular organismal reproductive behavior GO:0033057 110 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
regulation of response to stress GO:0080134 200 0.020
phosphorylation GO:0016310 294 0.020
ion transport GO:0006811 145 0.020
connective tissue development GO:0061448 3 0.019
epithelial cell differentiation GO:0030855 322 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
macromolecular complex assembly GO:0065003 256 0.019
cellular ketone metabolic process GO:0042180 24 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
activation of innate immune response GO:0002218 4 0.018
regulation of cell cycle GO:0051726 291 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
programmed cell death GO:0012501 257 0.018
acylglycerol catabolic process GO:0046464 3 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
cellular amine metabolic process GO:0044106 12 0.018
intracellular transport GO:0046907 228 0.018
positive regulation of gene expression GO:0010628 290 0.018
positive regulation of lipid storage GO:0010884 4 0.018
positive regulation of cell motility GO:2000147 3 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
ethanolamine containing compound metabolic process GO:0042439 4 0.017
response to lipopolysaccharide GO:0032496 4 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
taxis GO:0042330 304 0.017
protein transport GO:0015031 155 0.017
telencephalon development GO:0021537 2 0.017
response to organophosphorus GO:0046683 2 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
epithelial cell development GO:0002064 274 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
cholesterol transport GO:0030301 2 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
tube development GO:0035295 244 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
vitamin metabolic process GO:0006766 2 0.016
chromosome organization GO:0051276 360 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
acylglycerol biosynthetic process GO:0046463 2 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
antimicrobial humoral response GO:0019730 99 0.015
triglyceride biosynthetic process GO:0019432 2 0.015
phospholipid homeostasis GO:0055091 1 0.015
chemotaxis GO:0006935 249 0.015
regulation of catalytic activity GO:0050790 185 0.015
establishment of protein localization GO:0045184 163 0.015
immune effector process GO:0002252 98 0.015
purine containing compound metabolic process GO:0072521 155 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
regulation of molecular function GO:0065009 217 0.015
tube morphogenesis GO:0035239 191 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
actin filament based process GO:0030029 220 0.015
nucleotide metabolic process GO:0009117 161 0.015
localization of cell GO:0051674 257 0.015
regulation of cell differentiation GO:0045595 302 0.015
response to copper ion GO:0046688 4 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
triglyceride catabolic process GO:0019433 3 0.015
protein complex biogenesis GO:0070271 201 0.015
macromolecule catabolic process GO:0009057 161 0.015
gland morphogenesis GO:0022612 145 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
positive regulation of sequestering of triglyceride GO:0010890 1 0.014
adult behavior GO:0030534 137 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
humoral immune response GO:0006959 117 0.014
developmental maturation GO:0021700 172 0.014
chaeta development GO:0022416 97 0.014
ras protein signal transduction GO:0007265 88 0.014
innate immune response activating signal transduction GO:0002758 2 0.014
regulation of cell development GO:0060284 215 0.014
homeostatic process GO:0042592 199 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
central nervous system development GO:0007417 201 0.014
gene silencing GO:0016458 138 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of protein metabolic process GO:0051246 256 0.014
mitotic nuclear division GO:0007067 213 0.014
actin cytoskeleton organization GO:0030036 206 0.014
spindle organization GO:0007051 253 0.014
salivary gland morphogenesis GO:0007435 145 0.014
regulation of sequestering of triglyceride GO:0010889 3 0.014
phosphatidylethanolamine metabolic process GO:0046337 1 0.014
peptide metabolic process GO:0006518 80 0.014
cellular macromolecule localization GO:0070727 220 0.014
lateral inhibition GO:0046331 206 0.014
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.013
cell migration GO:0016477 238 0.013
response to temperature stimulus GO:0009266 106 0.013
regulation of lipid transport GO:0032368 3 0.013
regulation of immune response GO:0050776 118 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
pattern recognition receptor signaling pathway GO:0002221 2 0.013
organelle assembly GO:0070925 198 0.013
salivary gland histolysis GO:0035070 88 0.013
cell division GO:0051301 248 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
regulation of nervous system development GO:0051960 248 0.013
response to monosaccharide GO:0034284 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
oxidation reduction process GO:0055114 123 0.013
axon development GO:0061564 297 0.013
cellular response to organic substance GO:0071310 132 0.013
secondary metabolic process GO:0019748 75 0.013
regulation of response to external stimulus GO:0032101 115 0.013
maintenance of location GO:0051235 73 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
negative regulation of developmental process GO:0051093 201 0.013
salivary gland development GO:0007431 162 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
apoptotic process GO:0006915 159 0.013
single organism intracellular transport GO:1902582 207 0.013
cell motility GO:0048870 251 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
response to nutrient levels GO:0031667 114 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
rna processing GO:0006396 147 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
protein complex assembly GO:0006461 200 0.013
gland development GO:0048732 191 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
innate immune response GO:0045087 144 0.013
regulation of anatomical structure size GO:0090066 163 0.012
ovarian follicle cell development GO:0030707 248 0.012
dna metabolic process GO:0006259 227 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
hindbrain development GO:0030902 2 0.012
aromatic compound catabolic process GO:0019439 166 0.012
segmentation GO:0035282 207 0.012
cellular protein localization GO:0034613 160 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
regulation of cellular localization GO:0060341 136 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
positive regulation of transport GO:0051050 92 0.012
regulation of developmental growth GO:0048638 174 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
axis specification GO:0009798 167 0.012
chemical homeostasis GO:0048878 92 0.012
organophosphate catabolic process GO:0046434 112 0.012
histolysis GO:0007559 102 0.012
response to extracellular stimulus GO:0009991 116 0.012
exocrine system development GO:0035272 162 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
response to endogenous stimulus GO:0009719 119 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
regulation of cell death GO:0010941 173 0.012
embryonic morphogenesis GO:0048598 206 0.012
transmembrane transport GO:0055085 139 0.012
synaptic transmission GO:0007268 288 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
locomotory behavior GO:0007626 176 0.012
wnt signaling pathway GO:0016055 98 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
neuron projection guidance GO:0097485 241 0.012
lipid biosynthetic process GO:0008610 46 0.012
phosphatidic acid metabolic process GO:0046473 1 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
developmental programmed cell death GO:0010623 138 0.012
regulation of cell proliferation GO:0042127 163 0.012
protein phosphorylation GO:0006468 169 0.012
polyol biosynthetic process GO:0046173 3 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
chromatin modification GO:0016568 147 0.011
cellular amide metabolic process GO:0043603 80 0.011
positive regulation of molecular function GO:0044093 136 0.011
sulfur compound metabolic process GO:0006790 59 0.011
axon guidance GO:0007411 233 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
intracellular protein transport GO:0006886 104 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
chromatin remodeling GO:0006338 72 0.011
regulation of cell cycle process GO:0010564 181 0.011
xenobiotic catabolic process GO:0042178 1 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
positive regulation of immune response GO:0050778 63 0.011
limb development GO:0060173 1 0.011
regulation of phosphorylation GO:0042325 147 0.011
chromosome segregation GO:0007059 157 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
positive regulation of immune system process GO:0002684 68 0.011
regulation of growth GO:0040008 233 0.011
respiratory system development GO:0060541 213 0.011
positive regulation of defense response GO:0031349 59 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
secretion GO:0046903 109 0.011
pigmentation GO:0043473 75 0.011
heterocycle catabolic process GO:0046700 166 0.011
autophagic cell death GO:0048102 83 0.011
spermatogenesis GO:0007283 200 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
regulation of programmed cell death GO:0043067 152 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
membrane organization GO:0061024 112 0.011
digestive tract morphogenesis GO:0048546 127 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
organelle fission GO:0048285 340 0.011
vitamin biosynthetic process GO:0009110 1 0.011
monocarboxylic acid transport GO:0015718 3 0.011
mesenchymal cell development GO:0014031 1 0.011
fat soluble vitamin biosynthetic process GO:0042362 1 0.011
regulation of defense response GO:0031347 102 0.011
organelle localization GO:0051640 148 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
nuclear division GO:0000280 332 0.011
secretion by cell GO:0032940 101 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
response to organic cyclic compound GO:0014070 89 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
tissue death GO:0016271 102 0.011
mapk cascade GO:0000165 107 0.011
cation transport GO:0006812 110 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
endomembrane system organization GO:0010256 119 0.011
regulation of innate immune response GO:0045088 71 0.011
negative regulation of protein metabolic process GO:0051248 85 0.010
regulation of sterol transport GO:0032371 1 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
courtship behavior GO:0007619 68 0.010
camera type eye morphogenesis GO:0048593 2 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
response to radiation GO:0009314 155 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
regulation of organ morphogenesis GO:2000027 78 0.010
single organism cellular localization GO:1902580 180 0.010
positive regulation of catabolic process GO:0009896 105 0.010
response to hexose GO:0009746 3 0.010
regulation of organelle organization GO:0033043 196 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
autophagy GO:0006914 108 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
regulation of apoptotic process GO:0042981 130 0.010
dendrite morphogenesis GO:0048813 199 0.010
regulation of immune effector process GO:0002697 52 0.010
regulation of mapk cascade GO:0043408 92 0.010
response to organonitrogen compound GO:0010243 75 0.010
single organism membrane organization GO:0044802 93 0.010
cell adhesion GO:0007155 136 0.010
response to nitrogen compound GO:1901698 90 0.010
hormone catabolic process GO:0042447 3 0.010
regulation of synapse structure and activity GO:0050803 128 0.010
chromatin organization GO:0006325 207 0.010
steroid catabolic process GO:0006706 1 0.010
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
photoreceptor cell development GO:0042461 96 0.010

Spn43Ad disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
disease of metabolism DOID:0014667 0 0.023
nervous system disease DOID:863 0 0.020
inherited metabolic disorder DOID:655 0 0.019
glucose metabolism disease DOID:4194 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.017
diabetes mellitus DOID:9351 0 0.016
cardiovascular system disease DOID:1287 0 0.016
hair disease DOID:421 0 0.015
integumentary system disease DOID:16 0 0.015
hypotrichosis DOID:4535 0 0.015
lipid metabolism disorder DOID:3146 0 0.015
familial hypertriglyceridemia DOID:0050527 0 0.015
type 2 diabetes mellitus DOID:9352 0 0.014
vascular disease DOID:178 0 0.013
familial combined hyperlipidemia DOID:13809 0 0.013
familial hyperlipidemia DOID:1168 0 0.013
artery disease DOID:0050828 0 0.011
sensory system disease DOID:0050155 0 0.010
central nervous system disease DOID:331 0 0.010
urinary system disease DOID:18 0 0.010
hypertension DOID:10763 0 0.010