Drosophila melanogaster

138 known processes

tld (Dmel_CG6868)

tolloid

(Aliases: Tolloid,CG6868,Tld,dTld,CT21278,TLD,Dmel\CG6868)

tld biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
digestive tract development GO:0048565 149 0.949
Zebrafish
malpighian tubule morphogenesis GO:0007443 44 0.892
gastrulation with mouth forming first GO:0001703 36 0.855
gastrulation involving germ band extension GO:0010004 36 0.832
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.818
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 368 0.813
positive regulation of nucleic acid templated transcription GO:1903508 266 0.797
chemotaxis GO:0006935 249 0.795
Fly
tissue morphogenesis GO:0048729 297 0.784
Zebrafish
urogenital system development GO:0001655 72 0.779
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.768
Zebrafish
formation of primary germ layer GO:0001704 24 0.765
Zebrafish
negative regulation of transcription dna templated GO:0045892 237 0.764
digestive tract morphogenesis GO:0048546 127 0.749
Zebrafish
gastrulation GO:0007369 70 0.724
Zebrafish
positive regulation of transcription dna templated GO:0045893 266 0.718
digestive system development GO:0055123 149 0.705
Zebrafish
negative regulation of cell cycle process GO:0010948 109 0.698
growth GO:0040007 359 0.668
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.665
axon guidance GO:0007411 233 0.636
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.630
mesoderm morphogenesis GO:0048332 22 0.613
Zebrafish
negative regulation of cell cycle GO:0045786 116 0.609
exocrine system development GO:0035272 162 0.606
developmental growth GO:0048589 280 0.602
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.584
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.575
negative regulation of cellular biosynthetic process GO:0031327 277 0.566
organ growth GO:0035265 56 0.565
camera type eye development GO:0043010 4 0.546
compound eye morphogenesis GO:0001745 249 0.535
regulation of cell cycle GO:0051726 291 0.521
negative regulation of gene expression GO:0010629 387 0.518
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.516
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.515
regionalization GO:0003002 416 0.508
chromosome organization GO:0051276 360 0.496
tube morphogenesis GO:0035239 191 0.489
Zebrafish
imaginal disc derived wing morphogenesis GO:0007476 337 0.483
tube development GO:0035295 244 0.481
Zebrafish
stem cell differentiation GO:0048863 117 0.470
negative regulation of cell division GO:0051782 17 0.467
malpighian tubule development GO:0072002 64 0.463
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.458
bmp signaling pathway GO:0030509 27 0.446
Zebrafish
body morphogenesis GO:0010171 2 0.439
negative regulation of nucleic acid templated transcription GO:1903507 240 0.435
regulation of mitotic cell cycle GO:0007346 190 0.433
cell division GO:0051301 248 0.422
embryonic morphogenesis GO:0048598 206 0.420
Zebrafish
morphogenesis of embryonic epithelium GO:0016331 94 0.413
positive regulation of gene expression GO:0010628 290 0.412
endoderm formation GO:0001706 3 0.407
positive regulation of rna biosynthetic process GO:1902680 266 0.403
sensory organ morphogenesis GO:0090596 260 0.402
endodermal cell differentiation GO:0035987 3 0.401
camera type eye morphogenesis GO:0048593 2 0.389
regulation of mitotic cell cycle phase transition GO:1901990 130 0.388
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.386
muscle structure development GO:0061061 224 0.384
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.384
axonogenesis GO:0007409 290 0.370
Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.367
negative regulation of rna biosynthetic process GO:1902679 240 0.365
stem cell proliferation GO:0072089 88 0.357
positive regulation of rna metabolic process GO:0051254 271 0.356
regulation of chromosome organization GO:0033044 64 0.355
positive regulation of cellular biosynthetic process GO:0031328 316 0.353
positive regulation of response to stimulus GO:0048584 323 0.350
Zebrafish
positive regulation of biosynthetic process GO:0009891 316 0.348
anterior posterior pattern specification GO:0009952 136 0.346
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.344
eye development GO:0001654 323 0.339
regulation of cell fate commitment GO:0010453 29 0.324
imaginal disc derived wing vein specification GO:0007474 48 0.323
compound eye development GO:0048749 307 0.322
digestive tract mesoderm development GO:0007502 5 0.320
negative regulation of rna metabolic process GO:0051253 251 0.311
renal system development GO:0072001 72 0.310
negative regulation of signaling GO:0023057 219 0.309
mesoderm development GO:0007498 78 0.309
Zebrafish
hindgut morphogenesis GO:0007442 58 0.307
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.307
embryonic hindgut morphogenesis GO:0048619 48 0.303
endodermal cell fate commitment GO:0001711 3 0.299
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.295
Zebrafish
chromatin modification GO:0016568 147 0.292
protein modification process GO:0036211 438 0.291
regulation of developmental growth GO:0048638 174 0.289
negative regulation of cell cycle phase transition GO:1901988 103 0.282
regulation of organelle organization GO:0033043 196 0.260
segmentation GO:0035282 207 0.253
determination of dorsal ventral asymmetry GO:0048262 3 0.250
Zebrafish
cellular response to endogenous stimulus GO:0071495 80 0.248
mesenchymal cell differentiation GO:0048762 1 0.247
dorsal ventral pattern formation GO:0009953 133 0.242
regulation of nuclear division GO:0051783 58 0.241
cellular protein modification process GO:0006464 438 0.239
axon development GO:0061564 297 0.234
Fly
axis specification GO:0009798 167 0.231
neural precursor cell proliferation GO:0061351 75 0.228
motor neuron axon guidance GO:0008045 58 0.227
Fly
negative regulation of cell fate specification GO:0009996 15 0.219
stem cell development GO:0048864 79 0.218
chromatin remodeling GO:0006338 72 0.213
renal tubule development GO:0061326 64 0.212
chromatin organization GO:0006325 207 0.209
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.207
regulation of cellular amino acid metabolic process GO:0006521 0 0.207
regulation of cell cycle process GO:0010564 181 0.206
limb development GO:0060173 1 0.204
retina development in camera type eye GO:0060041 4 0.196
torso signaling pathway GO:0008293 21 0.195
embryonic development via the syncytial blastoderm GO:0001700 148 0.190
positive regulation of developmental process GO:0051094 143 0.190
Human
neuron projection guidance GO:0097485 241 0.190
Fly
cell fate specification GO:0001708 71 0.188
negative regulation of organelle organization GO:0010639 56 0.183
organonitrogen compound metabolic process GO:1901564 318 0.181
taxis GO:0042330 304 0.180
Fly
regulation of cell cycle phase transition GO:1901987 130 0.180
dna metabolic process GO:0006259 227 0.178
enzyme linked receptor protein signaling pathway GO:0007167 179 0.177
negative regulation of biosynthetic process GO:0009890 277 0.177
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.171
positive regulation of signal transduction GO:0009967 223 0.171
Zebrafish
regulation of multicellular organismal development GO:2000026 414 0.167
Human
cardioblast cell fate specification GO:0042685 9 0.166
regulation of cell development GO:0060284 215 0.165
connective tissue development GO:0061448 3 0.163
Human
regulation of chromatin modification GO:1903308 28 0.160
single organismal cell cell adhesion GO:0016337 45 0.158
regulation of stem cell differentiation GO:2000736 14 0.155
regulation of epithelial cell proliferation GO:0050678 4 0.153
dorsal closure GO:0007391 79 0.151
regulation of cell differentiation GO:0045595 302 0.150
response to organic substance GO:0010033 284 0.149
oxoacid metabolic process GO:0043436 103 0.149
cell cycle phase transition GO:0044770 140 0.149
gland morphogenesis GO:0022612 145 0.149
compound eye retinal cell programmed cell death GO:0046667 23 0.145
salivary gland development GO:0007431 162 0.142
response to endogenous stimulus GO:0009719 119 0.141
negative regulation of cellular metabolic process GO:0031324 382 0.140
negative regulation of developmental process GO:0051093 201 0.138
neuroblast fate commitment GO:0014017 19 0.137
cellular ketone metabolic process GO:0042180 24 0.137
cardiovascular system development GO:0072358 82 0.137
Zebrafish
covalent chromatin modification GO:0016569 106 0.135
regulation of reproductive process GO:2000241 54 0.134
apoptotic process GO:0006915 159 0.133
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.132
eye morphogenesis GO:0048592 260 0.131
chorion containing eggshell formation GO:0007304 105 0.131
somatic stem cell maintenance GO:0035019 14 0.130
epithelial cell development GO:0002064 274 0.128
Zebrafish
cardiocyte differentiation GO:0035051 29 0.128
mesoderm formation GO:0001707 21 0.128
Zebrafish
renal tubule morphogenesis GO:0061333 44 0.127
negative regulation of epithelial cell proliferation GO:0050680 4 0.127
immune system process GO:0002376 347 0.124
Zebrafish
death GO:0016265 284 0.120
stem cell division GO:0017145 69 0.119
negative regulation of cell differentiation GO:0045596 143 0.118
gland development GO:0048732 191 0.117
ovarian follicle cell development GO:0030707 248 0.116
nephron development GO:0072006 3 0.115
immune response GO:0006955 246 0.114
enteroendocrine cell differentiation GO:0035883 1 0.112
cellular amino acid metabolic process GO:0006520 61 0.112
wing disc morphogenesis GO:0007472 344 0.112
salivary gland morphogenesis GO:0007435 145 0.111
appendage morphogenesis GO:0035107 397 0.110
imaginal disc derived appendage morphogenesis GO:0035114 395 0.110
heart morphogenesis GO:0003007 32 0.107
regulation of organ formation GO:0003156 3 0.106
epithelial tube morphogenesis GO:0060562 88 0.105
reproductive system development GO:0061458 74 0.104
regulation of cell death GO:0010941 173 0.104
regulation of dna metabolic process GO:0051052 34 0.104
localization of cell GO:0051674 257 0.102
regulation of protein metabolic process GO:0051246 256 0.102
regulation of protein modification process GO:0031399 112 0.101
regulation of cell cell adhesion GO:0022407 21 0.101
positive regulation of developmental growth GO:0048639 62 0.100
regulation of cellular ketone metabolic process GO:0010565 3 0.100
neuroblast proliferation GO:0007405 74 0.099
muscle tissue morphogenesis GO:0060415 2 0.099
regulation of molecular function GO:0065009 217 0.098
regulation of antimicrobial humoral response GO:0002759 50 0.097
response to abiotic stimulus GO:0009628 341 0.097
dna dependent dna replication GO:0006261 17 0.096
spermatogenesis GO:0007283 200 0.096
mitotic dna damage checkpoint GO:0044773 74 0.096
cell cycle dna replication GO:0044786 23 0.095
organic acid metabolic process GO:0006082 103 0.094
cardiac cell fate commitment GO:0060911 17 0.094
muscle organ development GO:0007517 127 0.093
regulation of cell proliferation GO:0042127 163 0.093
signal transduction by phosphorylation GO:0023014 107 0.093
retina morphogenesis in camera type eye GO:0060042 2 0.093
regulation of programmed cell death GO:0043067 152 0.092
dna endoreduplication GO:0042023 22 0.091
tripartite regional subdivision GO:0007351 103 0.091
organelle fission GO:0048285 340 0.090
synapse organization GO:0050808 196 0.089
periodic partitioning GO:0007365 29 0.089
establishment of localization in cell GO:0051649 402 0.088
regulation of cell fate specification GO:0042659 27 0.088
limb morphogenesis GO:0035108 1 0.088
positive regulation of cell communication GO:0010647 250 0.088
Zebrafish
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.087
cardioblast differentiation GO:0010002 20 0.086
appendage development GO:0048736 401 0.086
dna replication GO:0006260 48 0.085
positive regulation of signaling GO:0023056 243 0.085
Zebrafish
mitotic cell cycle phase transition GO:0044772 138 0.084
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.084
blastoderm segmentation GO:0007350 159 0.083
head development GO:0060322 135 0.082
cell death GO:0008219 279 0.082
gonadal mesoderm development GO:0007506 8 0.082
positive regulation of cellular amine metabolic process GO:0033240 0 0.082
peptidyl amino acid modification GO:0018193 105 0.081
notch signaling pathway GO:0007219 120 0.081
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.081
regulation of cellular protein metabolic process GO:0032268 243 0.081
regulation of cardioblast differentiation GO:0051890 9 0.080
sex differentiation GO:0007548 81 0.080
regulation of intracellular signal transduction GO:1902531 236 0.080
positive regulation of protein modification process GO:0031401 58 0.080
nephron morphogenesis GO:0072028 3 0.080
morphogenesis of an epithelium GO:0002009 276 0.078
regulation of cellular amine metabolic process GO:0033238 3 0.075
kidney development GO:0001822 3 0.075
intracellular signal transduction GO:0035556 300 0.075
regulation of anatomical structure morphogenesis GO:0022603 242 0.074
cellular amine metabolic process GO:0044106 12 0.074
negative regulation of response to stimulus GO:0048585 258 0.074
homeostatic process GO:0042592 199 0.074
embryo development ending in birth or egg hatching GO:0009792 152 0.073
positive regulation of epithelial cell differentiation GO:0030858 1 0.073
male gamete generation GO:0048232 201 0.072
hindgut development GO:0061525 58 0.072
regulation of heart morphogenesis GO:2000826 3 0.072
regulation of organ morphogenesis GO:2000027 78 0.072
eggshell formation GO:0030703 105 0.072
regulation of mitosis GO:0007088 56 0.070
positive regulation of phosphorus metabolic process GO:0010562 139 0.070
single organism biosynthetic process GO:0044711 206 0.069
reproductive structure development GO:0048608 74 0.069
negative regulation of chromosome segregation GO:0051985 14 0.069
regulation of epithelial cell differentiation GO:0030856 4 0.068
circulatory system development GO:0072359 82 0.068
Zebrafish
positive regulation of growth GO:0045927 75 0.068
positive regulation of lipid metabolic process GO:0045834 4 0.066
chromosome segregation GO:0007059 157 0.066
negative regulation of signal transduction GO:0009968 206 0.065
regulation of bmp signaling pathway GO:0030510 23 0.065
Zebrafish
positive regulation of programmed cell death GO:0043068 62 0.065
neuromuscular junction development GO:0007528 149 0.065
imaginal disc pattern formation GO:0007447 91 0.064
regulation of cell projection organization GO:0031344 92 0.063
cell proliferation GO:0008283 299 0.063
regulation of notch signaling pathway GO:0008593 100 0.063
cell motility GO:0048870 251 0.063
columnar cuboidal epithelial cell development GO:0002066 249 0.063
negative regulation of stem cell differentiation GO:2000737 8 0.062
amine metabolic process GO:0009308 12 0.062
negative regulation of cell fate commitment GO:0010454 17 0.062
regulation of dendrite development GO:0050773 37 0.062
carboxylic acid metabolic process GO:0019752 92 0.061
heart development GO:0007507 82 0.061
negative regulation of smoothened signaling pathway GO:0045879 16 0.061
kidney morphogenesis GO:0060993 3 0.060
regulation of histone modification GO:0031056 20 0.060
stem cell maintenance GO:0019827 67 0.059
neuroblast fate specification GO:0014018 2 0.059
mitotic spindle organization GO:0007052 220 0.059
mitotic nuclear division GO:0007067 213 0.059
kidney epithelium development GO:0072073 3 0.058
central nervous system development GO:0007417 201 0.058
negative regulation of multicellular organismal process GO:0051241 142 0.058
regulation of growth GO:0040008 233 0.058
positive regulation of stem cell differentiation GO:2000738 3 0.058
negative regulation of hormone biosynthetic process GO:0032353 1 0.058
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.058
eye photoreceptor cell differentiation GO:0001754 145 0.057
dendrite development GO:0016358 204 0.056
positive regulation of muscle organ development GO:0048636 6 0.056
negative regulation of chromosome organization GO:2001251 19 0.056
positive regulation of cell death GO:0010942 69 0.056
hindbrain development GO:0030902 2 0.056
mesenchymal cell development GO:0014031 1 0.056
cellular response to chemical stimulus GO:0070887 199 0.056
forebrain development GO:0030900 2 0.055
regulation of chromatin organization GO:1902275 32 0.055
imaginal disc derived appendage development GO:0048737 399 0.055
regulation of retinal cell programmed cell death GO:0046668 18 0.054
regulation of cell morphogenesis GO:0022604 163 0.054
phosphorylation GO:0016310 294 0.054
negative regulation of notch signaling pathway GO:0045746 41 0.053
protein phosphorylation GO:0006468 169 0.053
positive regulation of cell proliferation GO:0008284 47 0.053
neuron fate commitment GO:0048663 50 0.053
vitamin metabolic process GO:0006766 2 0.053
response to transforming growth factor beta GO:0071559 18 0.053
morphogenesis of an epithelial bud GO:0060572 3 0.052
vesicle mediated transport GO:0016192 381 0.052
regulation of mapk cascade GO:0043408 92 0.051
regulation of neurogenesis GO:0050767 158 0.051
cytokinesis GO:0000910 90 0.051
post embryonic appendage morphogenesis GO:0035120 385 0.051
regulation of multicellular organism growth GO:0040014 40 0.051
stress activated protein kinase signaling cascade GO:0031098 55 0.051
myoblast proliferation GO:0051450 3 0.049
negative regulation of protein metabolic process GO:0051248 85 0.049
anterior posterior pattern specification imaginal disc GO:0007448 16 0.049
germline stem cell asymmetric division GO:0098728 15 0.047
positive regulation of cell migration GO:0030335 2 0.047
positive regulation of cellular component organization GO:0051130 156 0.047
protein localization GO:0008104 284 0.047
anterior malpighian tubule development GO:0061327 12 0.046
negative regulation of cell proliferation GO:0008285 69 0.046
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.046
positive regulation of phosphate metabolic process GO:0045937 139 0.045
negative regulation of nervous system development GO:0051961 92 0.045
multi multicellular organism process GO:0044706 123 0.045
eggshell chorion assembly GO:0007306 66 0.045
regulation of neuron differentiation GO:0045664 103 0.045
embryonic pattern specification GO:0009880 174 0.045
substrate dependent cell migration GO:0006929 3 0.045
regulation of axonogenesis GO:0050770 32 0.045
amide biosynthetic process GO:0043604 42 0.045
regulation of synapse structure and activity GO:0050803 128 0.044
regulation of stem cell proliferation GO:0072091 40 0.044
branching morphogenesis of an epithelial tube GO:0048754 45 0.044
imaginal disc growth GO:0007446 37 0.043
establishment of organelle localization GO:0051656 122 0.043
photoreceptor cell differentiation GO:0046530 170 0.043
negative regulation of cellular component organization GO:0051129 108 0.043
cellular catabolic process GO:0044248 372 0.043
apoptotic process involved in morphogenesis GO:0060561 3 0.042
histone acetylation GO:0016573 38 0.042
cardioblast cell fate commitment GO:0042684 14 0.042
modification dependent macromolecule catabolic process GO:0043632 79 0.042
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.041
regulation of transport GO:0051049 181 0.041
positive regulation of cellular protein metabolic process GO:0032270 118 0.040
stem cell fate commitment GO:0048865 25 0.040
synaptic transmission GO:0007268 288 0.040
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.040
germ band extension GO:0007377 11 0.040
wing disc pattern formation GO:0035222 66 0.040
germ cell migration GO:0008354 43 0.040
retinal cell programmed cell death GO:0046666 25 0.040
brain development GO:0007420 120 0.039
positive regulation of protein metabolic process GO:0051247 128 0.039
mesenchyme development GO:0060485 9 0.039
negative regulation of cell communication GO:0010648 223 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
anterior posterior axis specification GO:0009948 109 0.038
negative regulation of cell death GO:0060548 81 0.038
neuron fate specification GO:0048665 12 0.038
actin filament based process GO:0030029 220 0.036
single organism cell adhesion GO:0098602 47 0.036
methylation GO:0032259 47 0.036
maintenance of gastrointestinal epithelium GO:0030277 3 0.036
sensory perception GO:0007600 196 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.036
biological adhesion GO:0022610 138 0.036
phagocytosis GO:0006909 215 0.036
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.036
asymmetric stem cell division GO:0098722 49 0.036
glandular epithelial cell differentiation GO:0002067 1 0.036
nephron tubule morphogenesis GO:0072078 3 0.036
regulation of cell adhesion GO:0030155 27 0.035
segment polarity determination GO:0007367 25 0.035
protein localization to nucleus GO:0034504 55 0.035
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.034
mapk cascade GO:0000165 107 0.034
tissue migration GO:0090130 155 0.034
mitotic cytokinesis GO:0000281 50 0.034
response to biotic stimulus GO:0009607 294 0.034
spindle organization GO:0007051 253 0.034
regulation of immune response GO:0050776 118 0.034
response to oxygen containing compound GO:1901700 200 0.034
induction of programmed cell death GO:0012502 12 0.033
endoderm development GO:0007492 6 0.033
regulation of cellular response to stress GO:0080135 89 0.033
single organism catabolic process GO:0044712 228 0.033
negative regulation of apoptotic process GO:0043066 63 0.033
positive regulation of histone deacetylation GO:0031065 2 0.033
decapentaplegic signaling pathway GO:0008101 19 0.033
regulation of microtubule based process GO:0032886 49 0.033
multicellular organism growth GO:0035264 46 0.032
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.032
regulation of cellular catabolic process GO:0031329 157 0.032
hematopoietic or lymphoid organ development GO:0048534 57 0.032
Zebrafish
protein catabolic process GO:0030163 101 0.032
negative regulation of insulin secretion GO:0046676 1 0.031
mitotic cell cycle checkpoint GO:0007093 88 0.031
neuroblast differentiation GO:0014016 29 0.031
regulation of cell division GO:0051302 72 0.031
histone methylation GO:0016571 40 0.030
regulation of catabolic process GO:0009894 170 0.030
histolysis GO:0007559 102 0.030
secretion by cell GO:0032940 101 0.030
negative regulation of cell development GO:0010721 62 0.030
regulation of apoptotic process GO:0042981 130 0.030
head involution GO:0008258 35 0.030
negative regulation of cell cell adhesion GO:0022408 8 0.030
protein alkylation GO:0008213 43 0.030
morphogenesis of a branching epithelium GO:0061138 45 0.030
organic substance transport GO:0071702 257 0.030
molting cycle chitin based cuticle GO:0007591 56 0.030
regulation of decapentaplegic signaling pathway GO:0090097 8 0.030
regulation of protein localization GO:0032880 76 0.029
programmed cell death GO:0012501 257 0.029
double strand break repair GO:0006302 26 0.029
larval lymph gland hemopoiesis GO:0035167 17 0.029
wound healing GO:0042060 75 0.029
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.029
nephrocyte differentiation GO:0061319 12 0.029
nuclear division GO:0000280 332 0.029
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.029
neuron recognition GO:0008038 101 0.029
Fly
positive regulation of cell motility GO:2000147 3 0.029
regulation of myotube differentiation GO:0010830 6 0.029
ventral furrow formation GO:0007370 17 0.028
multicellular organismal reproductive behavior GO:0033057 110 0.028
pigmentation GO:0043473 75 0.028
stem cell fate specification GO:0048866 2 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
Human
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.027
cellular response to organic substance GO:0071310 132 0.027
mitotic sister chromatid segregation GO:0000070 87 0.027
neuromuscular synaptic transmission GO:0007274 67 0.027
somatic stem cell division GO:0048103 37 0.027
neuroblast division GO:0055057 35 0.026
cell cycle checkpoint GO:0000075 95 0.026
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.026
apoptotic process involved in development GO:1902742 20 0.026
regulation of cardiac cell fate specification GO:2000043 8 0.026
catabolic process GO:0009056 409 0.026
response to lipid GO:0033993 38 0.026
regulation of embryonic cell shape GO:0016476 30 0.026
maintenance of location in cell GO:0051651 28 0.026
eye photoreceptor cell fate commitment GO:0042706 37 0.026
positive regulation of nervous system development GO:0051962 69 0.026
regulation of heart induction GO:0090381 3 0.026
small molecule biosynthetic process GO:0044283 37 0.026
cellular response to dna damage stimulus GO:0006974 223 0.026
nephron epithelium morphogenesis GO:0072088 3 0.026
r7 cell development GO:0045467 14 0.026
cytoskeleton dependent cytokinesis GO:0061640 81 0.026
spinal cord development GO:0021510 1 0.026
hematopoietic progenitor cell differentiation GO:0002244 1 0.026
positive regulation of apoptotic process GO:0043065 47 0.026
stem cell fate determination GO:0048867 15 0.025
transmembrane transport GO:0055085 139 0.025
regulation of phosphorylation GO:0042325 147 0.025
equator specification GO:0045317 4 0.025
autophagic cell death GO:0048102 83 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
developmental pigmentation GO:0048066 68 0.025
neuronal stem cell division GO:0036445 35 0.025
protein maturation GO:0051604 71 0.025
somatic muscle development GO:0007525 66 0.025
stress activated mapk cascade GO:0051403 52 0.025
establishment or maintenance of cell polarity GO:0007163 167 0.025
chitin based cuticle development GO:0040003 49 0.025
positive regulation of organelle organization GO:0010638 65 0.025
regulation of dna replication GO:0006275 13 0.025
modification dependent protein catabolic process GO:0019941 78 0.025
negative regulation of catabolic process GO:0009895 36 0.025
humoral immune response GO:0006959 117 0.025
endocytosis GO:0006897 310 0.024
cellular amide metabolic process GO:0043603 80 0.024
small molecule metabolic process GO:0044281 305 0.024
positive regulation of lipid catabolic process GO:0050996 1 0.024
lipid metabolic process GO:0006629 121 0.024

tld disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.158
disease of cellular proliferation DOID:14566 0 0.158
organ system cancer DOID:0050686 0 0.158
disease of anatomical entity DOID:7 0 0.114
Human
musculoskeletal system cancer DOID:0060100 0 0.067
congenital heart disease DOID:1682 0 0.067
Human
heart disease DOID:114 0 0.067
Human
cardiovascular system disease DOID:1287 0 0.067
Human
musculoskeletal system disease DOID:17 0 0.047
Human
tetralogy of fallot DOID:6419 0 0.038
waardenburg s syndrome DOID:9258 0 0.034