Drosophila melanogaster

23 known processes

CG8486 (Dmel_CG8486)

CG8486 gene product from transcript CG8486-RE

(Aliases: anon-EST:Liang-1.32,Dmel\CG8486,clone 1.32)

CG8486 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to abiotic stimulus GO:0071214 58 0.646
single organism behavior GO:0044708 391 0.294
locomotory behavior GO:0007626 176 0.214
sensory perception of mechanical stimulus GO:0050954 72 0.205
enzyme linked receptor protein signaling pathway GO:0007167 179 0.155
sensory perception GO:0007600 196 0.143
detection of stimulus involved in sensory perception GO:0050906 92 0.141
detection of stimulus GO:0051606 156 0.133
response to abiotic stimulus GO:0009628 341 0.111
ocellus pigment metabolic process GO:0046158 19 0.105
biological adhesion GO:0022610 138 0.097
multi multicellular organism process GO:0044706 123 0.097
negative regulation of signaling GO:0023057 219 0.094
epiboly GO:0090504 2 0.091
taxis GO:0042330 304 0.090
transmembrane transport GO:0055085 139 0.090
organic substance transport GO:0071702 257 0.079
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.077
transcription from rna polymerase ii promoter GO:0006366 368 0.076
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.074
courtship behavior GO:0007619 68 0.069
inter male aggressive behavior GO:0002121 60 0.067
monocarboxylic acid transport GO:0015718 3 0.067
cellular response to dna damage stimulus GO:0006974 223 0.065
aggressive behavior GO:0002118 63 0.062
wing disc morphogenesis GO:0007472 344 0.062
cell cell signaling involved in cell fate commitment GO:0045168 210 0.061
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.061
synaptic transmission GO:0007268 288 0.059
regulation of synapse structure and activity GO:0050803 128 0.056
regionalization GO:0003002 416 0.055
ion transmembrane transport GO:0034220 122 0.054
small molecule metabolic process GO:0044281 305 0.054
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
neurological system process GO:0050877 358 0.050
cation transmembrane transport GO:0098655 88 0.050
single organism cellular localization GO:1902580 180 0.050
central nervous system development GO:0007417 201 0.049
response to monosaccharide GO:0034284 4 0.049
cellular response to endogenous stimulus GO:0071495 80 0.049
heart development GO:0007507 82 0.049
regulation of multicellular organismal development GO:2000026 414 0.049
multi organism reproductive behavior GO:0044705 121 0.049
carbohydrate homeostasis GO:0033500 12 0.048
localization of cell GO:0051674 257 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.046
lateral inhibition GO:0046331 206 0.046
regulation of synapse assembly GO:0051963 94 0.045
regulation of cell cycle g1 s phase transition GO:1902806 23 0.045
inorganic cation transmembrane transport GO:0098662 61 0.044
epiboly involved in wound healing GO:0090505 2 0.044
regulation of neurogenesis GO:0050767 158 0.043
posttranscriptional gene silencing by rna GO:0035194 45 0.043
vesicle mediated transport GO:0016192 381 0.042
response to glucose GO:0009749 2 0.041
spinal cord development GO:0021510 1 0.040
developmental pigmentation GO:0048066 68 0.039
body morphogenesis GO:0010171 2 0.039
wnt signaling pathway GO:0016055 98 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
protein modification process GO:0036211 438 0.038
chemotaxis GO:0006935 249 0.038
cell proliferation GO:0008283 299 0.037
negative regulation of response to stimulus GO:0048585 258 0.037
regulation of protein metabolic process GO:0051246 256 0.037
sensory perception of touch GO:0050975 11 0.036
retina development in camera type eye GO:0060041 4 0.036
cell adhesion GO:0007155 136 0.036
appendage morphogenesis GO:0035107 397 0.035
protein transport GO:0015031 155 0.035
response to hexose GO:0009746 3 0.034
regulation of cellular response to stress GO:0080135 89 0.034
eye pigmentation GO:0048069 43 0.033
carboxylic acid transport GO:0046942 18 0.033
embryonic morphogenesis GO:0048598 206 0.033
response to light stimulus GO:0009416 124 0.033
kidney epithelium development GO:0072073 3 0.032
negative regulation of cell communication GO:0010648 223 0.032
single organism intracellular transport GO:1902582 207 0.032
response to organic substance GO:0010033 284 0.032
circadian behavior GO:0048512 76 0.032
response to radiation GO:0009314 155 0.031
regulation of cellular component biogenesis GO:0044087 201 0.031
connective tissue development GO:0061448 3 0.031
response to biotic stimulus GO:0009607 294 0.031
cellular response to hexose stimulus GO:0071331 1 0.031
neuron recognition GO:0008038 101 0.031
periodic partitioning GO:0007365 29 0.031
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.030
developmental maturation GO:0021700 172 0.030
neuron projection guidance GO:0097485 241 0.030
intracellular transport GO:0046907 228 0.030
segmentation GO:0035282 207 0.030
regulation of localization GO:0032879 275 0.030
neuroblast division GO:0055057 35 0.029
heart process GO:0003015 37 0.029
endocytosis GO:0006897 310 0.029
mating GO:0007618 120 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
nephron development GO:0072006 3 0.029
renal system development GO:0072001 72 0.028
water homeostasis GO:0030104 3 0.028
cell migration GO:0016477 238 0.028
chemical homeostasis GO:0048878 92 0.027
cytoplasmic transport GO:0016482 130 0.027
regulation of ion transport GO:0043269 39 0.027
larval locomotory behavior GO:0008345 27 0.027
immune response activating signal transduction GO:0002757 2 0.027
circadian rhythm GO:0007623 105 0.027
cation homeostasis GO:0055080 51 0.027
organic acid transport GO:0015849 18 0.027
response to endogenous stimulus GO:0009719 119 0.027
cell recognition GO:0008037 102 0.027
cellular response to monosaccharide stimulus GO:0071326 2 0.026
cell projection assembly GO:0030031 94 0.026
anion transport GO:0006820 41 0.026
dorsal ventral pattern formation GO:0009953 133 0.025
male courtship behavior GO:0008049 63 0.025
response to external biotic stimulus GO:0043207 293 0.025
digestive system development GO:0055123 149 0.025
detection of external stimulus GO:0009581 66 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
sensory perception of pain GO:0019233 4 0.024
regulation of wnt signaling pathway GO:0030111 68 0.024
cellular protein modification process GO:0006464 438 0.024
negative regulation of signal transduction GO:0009968 206 0.023
amide biosynthetic process GO:0043604 42 0.023
mesenchymal cell differentiation GO:0048762 1 0.023
wound healing spreading of cells GO:0044319 2 0.023
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.023
cell division GO:0051301 248 0.023
nitrogen compound transport GO:0071705 85 0.023
sensory perception of salty taste GO:0050914 3 0.023
meiotic cell cycle GO:0051321 171 0.023
appendage development GO:0048736 401 0.022
phosphorylation GO:0016310 294 0.022
pigmentation GO:0043473 75 0.022
synaptic growth at neuromuscular junction GO:0051124 119 0.022
chromosome organization GO:0051276 360 0.022
mesenchymal cell development GO:0014031 1 0.022
hindgut development GO:0061525 58 0.022
ion transport GO:0006811 145 0.021
male mating behavior GO:0060179 70 0.021
salivary gland morphogenesis GO:0007435 145 0.021
response to pain GO:0048265 3 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
decapentaplegic signaling pathway GO:0008101 19 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
dendrite development GO:0016358 204 0.020
response to organonitrogen compound GO:0010243 75 0.020
brain development GO:0007420 120 0.020
metal ion homeostasis GO:0055065 44 0.020
response to nitrogen compound GO:1901698 90 0.020
regulation of cell cycle process GO:0010564 181 0.020
response to carbohydrate GO:0009743 15 0.020
kidney development GO:0001822 3 0.020
gastrulation GO:0007369 70 0.020
synapse assembly GO:0007416 143 0.020
hindgut morphogenesis GO:0007442 58 0.019
growth GO:0040007 359 0.019
developmental growth GO:0048589 280 0.019
regulation of nervous system development GO:0051960 248 0.019
cellular response to growth factor stimulus GO:0071363 30 0.019
meiotic nuclear division GO:0007126 151 0.019
response to wounding GO:0009611 94 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
nephron epithelium development GO:0072009 3 0.019
regulation of response to dna damage stimulus GO:2001020 23 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
phagocytosis GO:0006909 215 0.018
multicellular organismal reproductive behavior GO:0033057 110 0.018
embryonic pattern specification GO:0009880 174 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
cell cycle phase transition GO:0044770 140 0.018
positive regulation of protein transport GO:0051222 37 0.018
internal protein amino acid acetylation GO:0006475 38 0.018
regulation of cell cycle GO:0051726 291 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
defense response to other organism GO:0098542 225 0.017
cellular response to light stimulus GO:0071482 37 0.017
determination of adult lifespan GO:0008340 137 0.017
regulation of imaginal disc derived wing size GO:0044719 20 0.017
response to lipopolysaccharide GO:0032496 4 0.017
dendrite morphogenesis GO:0048813 199 0.017
chromatin organization GO:0006325 207 0.017
response to organophosphorus GO:0046683 2 0.017
regulation of organ morphogenesis GO:2000027 78 0.017
dorsal ventral axis specification GO:0009950 66 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
cellular response to insulin stimulus GO:0032869 28 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
posttranscriptional gene silencing GO:0016441 46 0.016
salt aversion GO:0035199 3 0.016
camera type eye morphogenesis GO:0048593 2 0.016
multicellular organism growth GO:0035264 46 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
positive regulation of gene expression GO:0010628 290 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
forebrain development GO:0030900 2 0.016
cellular macromolecule localization GO:0070727 220 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
regulation of protein modification process GO:0031399 112 0.016
ectodermal placode morphogenesis GO:0071697 4 0.016
regulation of transport GO:0051049 181 0.016
detection of chemical stimulus GO:0009593 93 0.016
negative regulation of gene expression GO:0010629 387 0.016
digestive tract morphogenesis GO:0048546 127 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
nephron morphogenesis GO:0072028 3 0.015
negative regulation of epithelial cell proliferation GO:0050680 4 0.015
spermatogenesis GO:0007283 200 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
camera type eye development GO:0043010 4 0.015
urogenital system development GO:0001655 72 0.015
cell adhesion mediated by integrin GO:0033627 12 0.015
imaginal disc pattern formation GO:0007447 91 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
developmental programmed cell death GO:0010623 138 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
cellular response to carbohydrate stimulus GO:0071322 4 0.015
homeostatic process GO:0042592 199 0.015
single organism biosynthetic process GO:0044711 206 0.015
cell motility GO:0048870 251 0.015
organelle fission GO:0048285 340 0.014
response to other organism GO:0051707 293 0.014
smoothened signaling pathway GO:0007224 49 0.014
salivary gland development GO:0007431 162 0.014
positive regulation of signaling GO:0023056 243 0.014
telencephalon development GO:0021537 2 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
regulation of molecular function GO:0065009 217 0.014
response to oxygen containing compound GO:1901700 200 0.014
detection of visible light GO:0009584 38 0.014
regulation of developmental growth GO:0048638 174 0.014
exocrine system development GO:0035272 162 0.014
positive regulation of nervous system development GO:0051962 69 0.014
positive regulation of cell motility GO:2000147 3 0.014
ommochrome biosynthetic process GO:0006727 19 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
convergent extension GO:0060026 2 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
wound healing spreading of epidermal cells GO:0035313 1 0.014
cellular response to organic substance GO:0071310 132 0.014
cellular response to chemical stimulus GO:0070887 199 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
regulation of membrane potential GO:0042391 35 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
stem cell proliferation GO:0072089 88 0.013
positive regulation of signal transduction GO:0009967 223 0.013
pigment biosynthetic process GO:0046148 36 0.013
axon guidance GO:0007411 233 0.013
microtubule based movement GO:0007018 51 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
protein localization GO:0008104 284 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
behavioral response to pain GO:0048266 3 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
multicellular organismal response to stress GO:0033555 5 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
multi organism behavior GO:0051705 175 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
positive regulation of epithelial cell differentiation GO:0030858 1 0.013
malpighian tubule morphogenesis GO:0007443 44 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
neuroblast proliferation GO:0007405 74 0.013
establishment of protein localization GO:0045184 163 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
secretion by cell GO:0032940 101 0.013
positive regulation of response to stimulus GO:0048584 323 0.012
asymmetric cell division GO:0008356 37 0.012
aromatic compound catabolic process GO:0019439 166 0.012
leg disc development GO:0035218 92 0.012
cellular response to organonitrogen compound GO:0071417 36 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
tissue morphogenesis GO:0048729 297 0.012
regulation of bmp signaling pathway GO:0030510 23 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
epithelial cell differentiation GO:0030855 322 0.012
spinal cord dorsal ventral patterning GO:0021513 1 0.012
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
establishment of localization in cell GO:0051649 402 0.012
response to bacterium GO:0009617 198 0.012
response to decreased oxygen levels GO:0036293 58 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
wound healing GO:0042060 75 0.012
nephron tubule morphogenesis GO:0072078 3 0.012
cellular catabolic process GO:0044248 372 0.012
ectodermal placode formation GO:0060788 4 0.012
male gamete generation GO:0048232 201 0.012
leg disc morphogenesis GO:0007478 80 0.012
gene silencing by rna GO:0031047 57 0.012
gland morphogenesis GO:0022612 145 0.012
long term memory GO:0007616 62 0.012
malpighian tubule development GO:0072002 64 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
intracellular signal transduction GO:0035556 300 0.012
regulation of multi organism process GO:0043900 131 0.012
response to acid chemical GO:0001101 25 0.012
endomembrane system organization GO:0010256 119 0.012
cellular response to acid chemical GO:0071229 8 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
negative regulation of protein metabolic process GO:0051248 85 0.011
salivary gland histolysis GO:0035070 88 0.011
ectodermal placode development GO:0071696 4 0.011
regulation of neuron differentiation GO:0045664 103 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
chromatin modification GO:0016568 147 0.011
monovalent inorganic cation transport GO:0015672 40 0.011
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
negative regulation of cell cycle GO:0045786 116 0.011
proximal distal pattern formation GO:0009954 15 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
nephron tubule development GO:0072080 3 0.011
activation of innate immune response GO:0002218 4 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
dorsal closure GO:0007391 79 0.011
organic substance catabolic process GO:1901575 308 0.011
respiratory system development GO:0060541 213 0.011
aging GO:0007568 143 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.011
spermatid differentiation GO:0048515 114 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
renal tubule development GO:0061326 64 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
catabolic process GO:0009056 409 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
digestive tract development GO:0048565 149 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
stress activated mapk cascade GO:0051403 52 0.011
response to growth factor GO:0070848 31 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.010
segment polarity determination GO:0007367 25 0.010
regulation of tube size GO:0035150 46 0.010
musculoskeletal movement GO:0050881 3 0.010
nuclear division GO:0000280 332 0.010
negative regulation of growth GO:0045926 84 0.010
positive regulation of transport GO:0051050 92 0.010
cation transport GO:0006812 110 0.010
neural retina development GO:0003407 4 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
sensory perception of taste GO:0050909 25 0.010
response to ketone GO:1901654 34 0.010
locomotor rhythm GO:0045475 56 0.010

CG8486 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.043
kidney disease DOID:557 0 0.043
disease of anatomical entity DOID:7 0 0.043
urinary system disease DOID:18 0 0.043
diabetes mellitus DOID:9351 0 0.037
disease of metabolism DOID:0014667 0 0.037
carbohydrate metabolism disease DOID:0050013 0 0.037
glucose metabolism disease DOID:4194 0 0.037
acquired metabolic disease DOID:0060158 0 0.037
cardiovascular system disease DOID:1287 0 0.019
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
connective tissue disease DOID:65 0 0.012
vascular disease DOID:178 0 0.010