Drosophila melanogaster

128 known processes

Sec61alpha (Dmel_CG9539)

CG9539 gene product from transcript CG9539-RA

(Aliases: Sec61-alpha,dSec61alpha,endd2,Dmel\CG9539,E(br)165,DSec61alpha,Sec61,anon-WO0118547.277,SEC61-alpha,LD29847,sec61alpha,l(2)k04917,SEC61ALPHA,sec61,0455,Sec61a,anon-WO0118547.195,BcDNA:LD29847,BEST:LD29847,CG9539)

Sec61alpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
respiratory system development GO:0060541 213 0.677
cellular protein localization GO:0034613 160 0.666
Yeast
programmed cell death GO:0012501 257 0.594
Worm
establishment of localization in cell GO:0051649 402 0.569
Yeast
tube development GO:0035295 244 0.471
catabolic process GO:0009056 409 0.462
cellular catabolic process GO:0044248 372 0.453
tube morphogenesis GO:0035239 191 0.446
small molecule metabolic process GO:0044281 305 0.432
organic substance transport GO:0071702 257 0.399
Yeast
digestive tract development GO:0048565 149 0.398
immune system process GO:0002376 347 0.393
embryo development ending in birth or egg hatching GO:0009792 152 0.359
ion transmembrane transport GO:0034220 122 0.312
regulation of transport GO:0051049 181 0.284
death GO:0016265 284 0.279
cell motility GO:0048870 251 0.252
response to other organism GO:0051707 293 0.249
proteolysis GO:0006508 192 0.233
Yeast
cellular macromolecule localization GO:0070727 220 0.230
Yeast
cell death GO:0008219 279 0.223
vesicle mediated transport GO:0016192 381 0.219
purine nucleoside catabolic process GO:0006152 112 0.214
organonitrogen compound metabolic process GO:1901564 318 0.172
mitotic spindle organization GO:0007052 220 0.170
secretion GO:0046903 109 0.165
nucleotide catabolic process GO:0009166 109 0.162
larval development GO:0002164 104 0.161
regulation of cell adhesion GO:0030155 27 0.157
single organism catabolic process GO:0044712 228 0.157
biological adhesion GO:0022610 138 0.156
apoptotic process GO:0006915 159 0.152
Worm
spindle organization GO:0007051 253 0.151
cell migration GO:0016477 238 0.151
secretion by cell GO:0032940 101 0.143
protein localization to organelle GO:0033365 82 0.121
Yeast
homeostatic process GO:0042592 199 0.117
purine ribonucleotide catabolic process GO:0009154 109 0.112
purine nucleoside metabolic process GO:0042278 127 0.110
glycosyl compound catabolic process GO:1901658 112 0.108
localization of cell GO:0051674 257 0.105
gland morphogenesis GO:0022612 145 0.101
molting cycle chitin based cuticle GO:0007591 56 0.099
nucleoside triphosphate metabolic process GO:0009141 120 0.096
carbohydrate derivative metabolic process GO:1901135 217 0.093
synaptic transmission GO:0007268 288 0.093
maintenance of location GO:0051235 73 0.088
endomembrane system organization GO:0010256 119 0.087
regulation of localization GO:0032879 275 0.084
peptide metabolic process GO:0006518 80 0.081
single organism biosynthetic process GO:0044711 206 0.074
cuticle development GO:0042335 86 0.073
oxoacid metabolic process GO:0043436 103 0.072
response to organic substance GO:0010033 284 0.070
single organism intracellular transport GO:1902582 207 0.070
Yeast
cellular ketone metabolic process GO:0042180 24 0.065
organic substance catabolic process GO:1901575 308 0.064
Yeast
cellular amide metabolic process GO:0043603 80 0.064
intracellular protein transport GO:0006886 104 0.064
Yeast
digestive tract morphogenesis GO:0048546 127 0.061
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.059
ribonucleoside catabolic process GO:0042454 112 0.059
intracellular transport GO:0046907 228 0.059
Yeast
male gamete generation GO:0048232 201 0.059
tissue morphogenesis GO:0048729 297 0.058
cardiocyte differentiation GO:0035051 29 0.057
negative regulation of autophagy GO:0010507 16 0.057
open tracheal system development GO:0007424 204 0.055
purine ribonucleoside catabolic process GO:0046130 112 0.054
lateral inhibition GO:0046331 206 0.053
protein localization GO:0008104 284 0.052
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.051
cellular homeostasis GO:0019725 80 0.050
nucleoside phosphate metabolic process GO:0006753 162 0.050
multicellular organismal aging GO:0010259 140 0.050
ribose phosphate metabolic process GO:0019693 145 0.049
organic acid metabolic process GO:0006082 103 0.049
nucleoside catabolic process GO:0009164 112 0.049
negative regulation of response to stimulus GO:0048585 258 0.049
purine nucleotide catabolic process GO:0006195 109 0.047
phagocytosis GO:0006909 215 0.047
germ band shortening GO:0007390 19 0.046
purine nucleoside triphosphate catabolic process GO:0009146 108 0.045
molting cycle GO:0042303 56 0.044
appendage morphogenesis GO:0035107 397 0.044
endocytosis GO:0006897 310 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.043
single organism cellular localization GO:1902580 180 0.042
Yeast
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.042
axon guidance GO:0007411 233 0.042
negative regulation of cell communication GO:0010648 223 0.042
cellular response to organic substance GO:0071310 132 0.042
purine containing compound catabolic process GO:0072523 112 0.042
wing disc morphogenesis GO:0007472 344 0.042
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
ribonucleotide catabolic process GO:0009261 109 0.041
cellular response to chemical stimulus GO:0070887 199 0.039
synaptic vesicle recycling GO:0036465 28 0.039
purine containing compound metabolic process GO:0072521 155 0.038
nucleoside metabolic process GO:0009116 127 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
epithelial cell differentiation GO:0030855 322 0.036
negative regulation of gene expression GO:0010629 387 0.036
embryonic morphogenesis GO:0048598 206 0.036
regulation of cell migration GO:0030334 22 0.035
regulation of cellular component movement GO:0051270 42 0.034
peptidyl amino acid modification GO:0018193 105 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.033
dendrite development GO:0016358 204 0.032
digestive system development GO:0055123 149 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.031
regulation of locomotion GO:0040012 42 0.031
cognition GO:0050890 141 0.029
response to nutrient levels GO:0031667 114 0.029
protein transport GO:0015031 155 0.029
Yeast
regulation of secretion by cell GO:1903530 39 0.029
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.028
ribonucleoside metabolic process GO:0009119 127 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
positive regulation of secretion by cell GO:1903532 20 0.027
chemotaxis GO:0006935 249 0.027
head development GO:0060322 135 0.027
Zebrafish
neuromuscular synaptic transmission GO:0007274 67 0.027
cell adhesion GO:0007155 136 0.027
regulation of multi organism process GO:0043900 131 0.027
regulation of response to oxidative stress GO:1902882 4 0.027
salivary gland development GO:0007431 162 0.026
gastrulation GO:0007369 70 0.026
body morphogenesis GO:0010171 2 0.025
positive regulation of cell migration GO:0030335 2 0.025
protein localization to membrane GO:0072657 19 0.025
Yeast
chitin based cuticle development GO:0040003 49 0.025
regulation of intracellular signal transduction GO:1902531 236 0.024
lipid storage GO:0019915 38 0.024
anatomical structure homeostasis GO:0060249 97 0.024
positive regulation of transport GO:0051050 92 0.024
establishment of protein localization GO:0045184 163 0.024
Yeast
dendrite morphogenesis GO:0048813 199 0.024
regulation of growth GO:0040008 233 0.024
negative regulation of cell death GO:0060548 81 0.023
regulation of reproductive process GO:2000241 54 0.023
learning or memory GO:0007611 141 0.022
positive regulation of secretion GO:0051047 22 0.022
forebrain development GO:0030900 2 0.021
Zebrafish
regulation of secretion GO:0051046 44 0.021
regulation of cuticle pigmentation GO:0048079 16 0.021
cuticle pigmentation GO:0048067 22 0.021
spermatogenesis GO:0007283 200 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of cellular localization GO:0060341 136 0.020
lipid localization GO:0010876 54 0.020
glycoprotein metabolic process GO:0009100 41 0.020
neuron projection guidance GO:0097485 241 0.020
purine nucleotide metabolic process GO:0006163 146 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
cytokinesis GO:0000910 90 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
morphogenesis of a branching structure GO:0001763 45 0.019
brain development GO:0007420 120 0.019
Zebrafish
learning GO:0007612 75 0.018
cytoplasmic transport GO:0016482 130 0.018
Yeast
nucleobase containing compound catabolic process GO:0034655 165 0.018
wing disc pattern formation GO:0035222 66 0.018
negative regulation of apoptotic process GO:0043066 63 0.018
peptide hormone processing GO:0016486 2 0.018
morphogenesis of an epithelium GO:0002009 276 0.017
aging GO:0007568 143 0.017
cellular protein catabolic process GO:0044257 83 0.017
Yeast
anion transport GO:0006820 41 0.017
cell chemotaxis GO:0060326 6 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
response to oxidative stress GO:0006979 86 0.017
response to extracellular stimulus GO:0009991 116 0.016
cellular protein modification process GO:0006464 438 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
purine nucleoside biosynthetic process GO:0042451 3 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
Yeast
response to topologically incorrect protein GO:0035966 10 0.016
defense response to bacterium GO:0042742 178 0.016
membrane organization GO:0061024 112 0.016
Yeast
regulation of hemocyte proliferation GO:0035206 37 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
regulation of tube architecture open tracheal system GO:0035152 68 0.015
negative regulation of signaling GO:0023057 219 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
visual learning GO:0008542 4 0.014
transmembrane transport GO:0055085 139 0.014
growth GO:0040007 359 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
maintenance of protein location in cell GO:0032507 26 0.014
nitrogen compound transport GO:0071705 85 0.014
Yeast
positive regulation of multicellular organismal process GO:0051240 143 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
gland development GO:0048732 191 0.014
inorganic ion transmembrane transport GO:0098660 73 0.013
regulation of cell death GO:0010941 173 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
regulation of molecular function GO:0065009 217 0.013
gastrulation involving germ band extension GO:0010004 36 0.013
epithelial cell development GO:0002064 274 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
regulation of phosphatase activity GO:0010921 3 0.013
ion transport GO:0006811 145 0.013
olfactory learning GO:0008355 56 0.013
regulation of apoptotic process GO:0042981 130 0.013
regulation of programmed cell death GO:0043067 152 0.013
chemical homeostasis GO:0048878 92 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
positive regulation of cell substrate adhesion GO:0010811 1 0.012
positive regulation of developmental pigmentation GO:0048087 5 0.012
intracellular signal transduction GO:0035556 300 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
embryonic organ development GO:0048568 50 0.012
axonogenesis GO:0007409 290 0.012
dorsal closure GO:0007391 79 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
amino sugar biosynthetic process GO:0046349 5 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.011
olfactory behavior GO:0042048 97 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
protein catabolic process GO:0030163 101 0.011
Yeast
response to external biotic stimulus GO:0043207 293 0.011
gtp metabolic process GO:0046039 72 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
calcium ion homeostasis GO:0055074 23 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
trachea development GO:0060438 29 0.011
macromolecule catabolic process GO:0009057 161 0.011
Yeast
regulation of embryonic development GO:0045995 68 0.010
regulation of proteolysis GO:0030162 87 0.010
chaeta development GO:0022416 97 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
adult locomotory behavior GO:0008344 76 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
Yeast
sodium ion transport GO:0006814 22 0.010
cellular metal ion homeostasis GO:0006875 31 0.010
maintenance of location in cell GO:0051651 28 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
cardiovascular system development GO:0072358 82 0.010

Sec61alpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org