Drosophila melanogaster

239 known processes

Pvr (Dmel_CG8222)

PDGF- and VEGF-receptor related

(Aliases: Dmel\CG8222,DmVEGFR,PVR,Vegfr-b,Vegfr-c,VEGFR,CT24332,VEGFR-A,8222,CG8222,Vgr1,Vegfr,pvr,Vegf,vgr1,VGR1,stai)

Pvr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell migration GO:0007297 121 1.000
border follicle cell migration GO:0007298 113 1.000
hemocyte migration GO:0035099 19 0.999
epithelial cell migration GO:0010631 148 0.999
ameboidal type cell migration GO:0001667 151 0.996
epithelium migration GO:0090132 148 0.992
ovarian follicle cell development GO:0030707 248 0.990
cell motility GO:0048870 251 0.985
cell migration GO:0016477 238 0.977
columnar cuboidal epithelial cell development GO:0002066 249 0.977
embryonic hemopoiesis GO:0035162 26 0.976
defense response to other organism GO:0098542 225 0.964
immune system process GO:0002376 347 0.964
striated muscle cell differentiation GO:0051146 90 0.958
Mouse
tissue migration GO:0090130 155 0.940
humoral immune response GO:0006959 117 0.931
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.925
Human Mouse
epithelial cell development GO:0002064 274 0.918
organonitrogen compound metabolic process GO:1901564 318 0.873
Mouse Rat
response to other organism GO:0051707 293 0.865
cell projection assembly GO:0030031 94 0.864
axonogenesis GO:0007409 290 0.853
regulation of cell projection organization GO:0031344 92 0.852
regulation of anatomical structure morphogenesis GO:0022603 242 0.850
antimicrobial humoral response GO:0019730 99 0.849
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.835
respiratory system development GO:0060541 213 0.827
Mouse
negative regulation of response to stimulus GO:0048585 258 0.819
Human
positive regulation of response to stimulus GO:0048584 323 0.807
neuron projection guidance GO:0097485 241 0.800
intracellular signal transduction GO:0035556 300 0.799
response to external biotic stimulus GO:0043207 293 0.781
immune effector process GO:0002252 98 0.781
Human Mouse
reactive oxygen species metabolic process GO:0072593 22 0.767
Mouse
epithelial cell differentiation GO:0030855 322 0.761
digestive tract development GO:0048565 149 0.753
death GO:0016265 284 0.734
metal ion homeostasis GO:0055065 44 0.709
Human Mouse
catabolic process GO:0009056 409 0.707
pigment metabolic process GO:0042440 84 0.689
digestive system development GO:0055123 149 0.688
cell death GO:0008219 279 0.679
homeostatic process GO:0042592 199 0.676
hematopoietic or lymphoid organ development GO:0048534 57 0.665
peptide metabolic process GO:0006518 80 0.662
tube development GO:0035295 244 0.660
positive regulation of cellular biosynthetic process GO:0031328 316 0.658
Human Mouse
tube morphogenesis GO:0035239 191 0.649
regulation of multicellular organismal development GO:2000026 414 0.643
Human Zebrafish Mouse Rat
endocytosis GO:0006897 310 0.630
localization of cell GO:0051674 257 0.627
response to biotic stimulus GO:0009607 294 0.619
regulation of immune system process GO:0002682 176 0.613
apoptotic cell clearance GO:0043277 14 0.611
vesicle mediated transport GO:0016192 381 0.597
Human
multicellular organismal homeostasis GO:0048871 41 0.591
Mouse Rat
morphogenesis of embryonic epithelium GO:0016331 94 0.584
hemopoiesis GO:0030097 46 0.583
positive regulation of cellular component organization GO:0051130 156 0.583
Human Mouse
regulation of cell shape GO:0008360 113 0.581
appendage development GO:0048736 401 0.580
tissue homeostasis GO:0001894 36 0.580
Mouse Rat
positive regulation of rna metabolic process GO:0051254 271 0.567
cell junction organization GO:0034330 57 0.558
Human
cellular response to chemical stimulus GO:0070887 199 0.555
digestive tract morphogenesis GO:0048546 127 0.544
regulation of immune response GO:0050776 118 0.536
Human
secondary metabolic process GO:0019748 75 0.530
striated muscle cell development GO:0055002 50 0.517
Mouse
paracrine signaling GO:0038001 7 0.516
exocrine system development GO:0035272 162 0.514
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.505
muscle cell differentiation GO:0042692 103 0.500
Mouse
morphogenesis of an epithelium GO:0002009 276 0.495
positive regulation of transcription dna templated GO:0045893 266 0.495
imaginal disc derived wing hair organization GO:0035317 45 0.495
response to bacterium GO:0009617 198 0.493
anatomical structure homeostasis GO:0060249 97 0.492
Mouse Rat
immune system development GO:0002520 57 0.482
defense response to bacterium GO:0042742 178 0.481
regulation of cell morphogenesis GO:0022604 163 0.476
cellular ion homeostasis GO:0006873 39 0.475
Human
extracellular structure organization GO:0043062 46 0.470
Mouse
open tracheal system development GO:0007424 204 0.469
taxis GO:0042330 304 0.467
Human Zebrafish Mouse
growth GO:0040007 359 0.461
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.451
Mouse
actin filament based process GO:0030029 220 0.435
cellular ketone metabolic process GO:0042180 24 0.424
regulation of response to stress GO:0080134 200 0.420
Human
gland development GO:0048732 191 0.410
response to mechanical stimulus GO:0009612 28 0.409
Mouse
apoptotic process GO:0006915 159 0.405
cellular catabolic process GO:0044248 372 0.405
embryonic development via the syncytial blastoderm GO:0001700 148 0.403
carbohydrate derivative metabolic process GO:1901135 217 0.396
Mouse Rat
immune response GO:0006955 246 0.392
regulation of neuron differentiation GO:0045664 103 0.387
cell cell junction organization GO:0045216 55 0.385
Human
cell proliferation GO:0008283 299 0.385
Human Mouse Rat
protein localization GO:0008104 284 0.373
Human
positive regulation of developmental process GO:0051094 143 0.370
Human Zebrafish Mouse Rat
embryonic morphogenesis GO:0048598 206 0.369
axon guidance GO:0007411 233 0.365
cell substrate adhesion GO:0031589 10 0.361
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.361
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.359
positive regulation of biosynthetic process GO:0009891 316 0.355
Human Mouse Rat
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.351
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.345
hindgut development GO:0061525 58 0.344
embryonic organ development GO:0048568 50 0.338
defense response GO:0006952 300 0.337
imaginal disc derived leg morphogenesis GO:0007480 80 0.329
post embryonic appendage morphogenesis GO:0035120 385 0.326
actin filament organization GO:0007015 126 0.326
programmed cell death GO:0012501 257 0.322
regulation of neuron death GO:1901214 26 0.322
defense response to gram negative bacterium GO:0050829 94 0.321
enzyme linked receptor protein signaling pathway GO:0007167 179 0.321
Human Zebrafish Mouse Rat
cell adhesion GO:0007155 136 0.316
Human Mouse
pericardium morphogenesis GO:0003344 2 0.314
regulation of cell death GO:0010941 173 0.306
positive regulation of nucleic acid templated transcription GO:1903508 266 0.305
small molecule metabolic process GO:0044281 305 0.298
biological adhesion GO:0022610 138 0.297
Human Mouse
phagocytosis engulfment GO:0006911 11 0.292
actin filament bundle organization GO:0061572 28 0.283
cellular metal ion homeostasis GO:0006875 31 0.276
Human
melanization defense response GO:0035006 45 0.274
multi organism reproductive behavior GO:0044705 121 0.273
regulation of multi organism process GO:0043900 131 0.272
glial cell development GO:0021782 27 0.269
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.269
Human Zebrafish Mouse Rat
reproductive structure development GO:0048608 74 0.269
regulation of filopodium assembly GO:0051489 24 0.268
single organism catabolic process GO:0044712 228 0.263
regulation of protein metabolic process GO:0051246 256 0.257
Human Mouse Rat
response to wounding GO:0009611 94 0.257
Human Mouse Rat
dorsal ventral pattern formation GO:0009953 133 0.256
regulation of phosphate metabolic process GO:0019220 210 0.256
membrane organization GO:0061024 112 0.254
body morphogenesis GO:0010171 2 0.253
Mouse
filopodium assembly GO:0046847 33 0.249
regulation of anatomical structure size GO:0090066 163 0.249
positive regulation of cell differentiation GO:0045597 64 0.246
Mouse Rat
positive regulation of immune system process GO:0002684 68 0.245
Zebrafish Mouse Rat
melanin metabolic process GO:0006582 47 0.243
regulation of cellular component size GO:0032535 98 0.240
regulation of neurogenesis GO:0050767 158 0.238
cellular homeostasis GO:0019725 80 0.238
Human
positive regulation of protein metabolic process GO:0051247 128 0.238
Human Mouse Rat
dorsal closure GO:0007391 79 0.237
neurological system process GO:0050877 358 0.237
Mouse
phagocytosis GO:0006909 215 0.233
ion transmembrane transport GO:0034220 122 0.232
Mouse
chemotaxis GO:0006935 249 0.230
Human Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.224
Human Mouse
cellular amino acid metabolic process GO:0006520 61 0.223
negative regulation of signaling GO:0023057 219 0.222
dna metabolic process GO:0006259 227 0.219
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.219
Mouse
positive regulation of phagocytosis engulfment GO:0060100 1 0.219
negative regulation of cell communication GO:0010648 223 0.219
regulation of production of molecular mediator of immune response GO:0002700 44 0.218
antimicrobial peptide production GO:0002775 46 0.212
skeletal muscle organ development GO:0060538 48 0.212
Rat
regulation of cellular component biogenesis GO:0044087 201 0.211
Human
regulation of nervous system development GO:0051960 248 0.210
negative regulation of multicellular organismal process GO:0051241 142 0.210
Human Mouse
regulation of mapk cascade GO:0043408 92 0.204
cellular component assembly involved in morphogenesis GO:0010927 151 0.197
Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.197
single organismal cell cell adhesion GO:0016337 45 0.192
Human Mouse
cell matrix adhesion GO:0007160 6 0.192
Human
cellular amide metabolic process GO:0043603 80 0.190
regulation of phosphorus metabolic process GO:0051174 210 0.189
regulation of cell differentiation GO:0045595 302 0.186
wing disc morphogenesis GO:0007472 344 0.183
leg disc development GO:0035218 92 0.182
extracellular matrix organization GO:0030198 32 0.180
Mouse
axon development GO:0061564 297 0.179
stem cell proliferation GO:0072089 88 0.176
Mouse
response to oxygen containing compound GO:1901700 200 0.175
oocyte development GO:0048599 124 0.173
establishment of localization in cell GO:0051649 402 0.173
Human
positive regulation of cell communication GO:0010647 250 0.172
oocyte growth GO:0001555 5 0.172
autophagy GO:0006914 108 0.170
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.170
carboxylic acid metabolic process GO:0019752 92 0.170
regulation of cell projection assembly GO:0060491 30 0.169
regulation of response to wounding GO:1903034 19 0.169
Human
regulation of metal ion transport GO:0010959 15 0.168
Mouse
positive regulation of response to external stimulus GO:0032103 44 0.158
Human Zebrafish Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.158
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.157
transcription from rna polymerase ii promoter GO:0006366 368 0.157
oxoacid metabolic process GO:0043436 103 0.155
organic hydroxy compound metabolic process GO:1901615 83 0.155
muscle cell development GO:0055001 50 0.154
Mouse
muscle attachment GO:0016203 36 0.153
multi organism behavior GO:0051705 175 0.151
regulation of locomotion GO:0040012 42 0.151
Human Zebrafish Mouse Rat
positive regulation of nervous system development GO:0051962 69 0.149
regulation of cell cell adhesion GO:0022407 21 0.149
developmental maturation GO:0021700 172 0.147
Mouse
response to fungus GO:0009620 50 0.146
basement membrane organization GO:0071711 10 0.145
regulation of defense response to fungus GO:1900150 6 0.144
single organism cell adhesion GO:0098602 47 0.143
Human Mouse
positive regulation of antifungal peptide production GO:0002804 6 0.141
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.141
Human Mouse Rat
erbb signaling pathway GO:0038127 58 0.139
negative regulation of developmental process GO:0051093 201 0.138
Mouse
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.138
establishment or maintenance of cell polarity GO:0007163 167 0.136
cellular divalent inorganic cation homeostasis GO:0072503 23 0.136
Human
cellular response to reactive oxygen species GO:0034614 14 0.136
associative learning GO:0008306 65 0.134
positive regulation of signal transduction GO:0009967 223 0.134
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.134
cellular amine metabolic process GO:0044106 12 0.133
heart morphogenesis GO:0003007 32 0.132
nucleotide metabolic process GO:0009117 161 0.131
imaginal disc derived wing morphogenesis GO:0007476 337 0.130
cation homeostasis GO:0055080 51 0.130
Human Mouse
response to virus GO:0009615 28 0.129
reproductive system development GO:0061458 74 0.128
stress activated protein kinase signaling cascade GO:0031098 55 0.127
Human
positive regulation of molecular function GO:0044093 136 0.126
Human Mouse Rat
positive regulation of cell development GO:0010720 61 0.125
regulation of immune effector process GO:0002697 52 0.124
regulation of cellular protein metabolic process GO:0032268 243 0.123
Human Mouse Rat
antifungal peptide biosynthetic process GO:0002783 5 0.121
regulation of intracellular signal transduction GO:1902531 236 0.121
hindgut morphogenesis GO:0007442 58 0.120
gastrulation GO:0007369 70 0.117
positive regulation of defense response GO:0031349 59 0.117
regulation of apoptotic process GO:0042981 130 0.117
organelle fission GO:0048285 340 0.116
Mouse
cardiocyte differentiation GO:0035051 29 0.115
Mouse
positive regulation of cell projection organization GO:0031346 29 0.115
actin filament based movement GO:0030048 26 0.115
negative regulation of rho protein signal transduction GO:0035024 1 0.113
organic substance catabolic process GO:1901575 308 0.113
epidermal growth factor receptor signaling pathway GO:0007173 58 0.112
positive regulation of cellular amine metabolic process GO:0033240 0 0.111
hemocyte differentiation GO:0042386 38 0.111
cell junction assembly GO:0034329 42 0.110
Human
salivary gland morphogenesis GO:0007435 145 0.108
multi multicellular organism process GO:0044706 123 0.107
secretion GO:0046903 109 0.107
Human
positive regulation of cytoskeleton organization GO:0051495 21 0.106
negative regulation of apoptotic process GO:0043066 63 0.106
positive regulation of immune effector process GO:0002699 28 0.105
striated muscle tissue development GO:0014706 27 0.105
Mouse Rat
cell cell adhesion mediated by integrin GO:0033631 1 0.103
chaeta development GO:0022416 97 0.102
negative regulation of cell death GO:0060548 81 0.101
single organism biosynthetic process GO:0044711 206 0.100
Rat
chromatin organization GO:0006325 207 0.099
nucleobase containing small molecule metabolic process GO:0055086 174 0.098
positive regulation of cell adhesion GO:0045785 10 0.098
Human
malpighian tubule morphogenesis GO:0007443 44 0.098
regulation of cytoskeleton organization GO:0051493 89 0.097
Mouse
regulation of cellular amide metabolic process GO:0034248 39 0.096
epithelial structure maintenance GO:0010669 17 0.096
organonitrogen compound biosynthetic process GO:1901566 117 0.095
Rat
appendage morphogenesis GO:0035107 397 0.095
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.094
compound eye development GO:0048749 307 0.094
response to organic cyclic compound GO:0014070 89 0.093
Rat
positive regulation of cell migration GO:0030335 2 0.093
Human Zebrafish Mouse Rat
positive regulation of phagocytosis GO:0050766 3 0.092
determination of digestive tract left right asymmetry GO:0071907 6 0.092
divalent metal ion transport GO:0070838 26 0.092
Mouse
dorsal trunk growth open tracheal system GO:0035001 7 0.091
regulation of dna metabolic process GO:0051052 34 0.091
Human Mouse
innate immune response GO:0045087 144 0.090
maintenance of location GO:0051235 73 0.090
positive regulation of endocytosis GO:0045807 22 0.089
developmental growth GO:0048589 280 0.089
purine containing compound metabolic process GO:0072521 155 0.089
sensory perception GO:0007600 196 0.089
Mouse
regulation of antimicrobial humoral response GO:0002759 50 0.088
glial cell differentiation GO:0010001 35 0.088
Zebrafish
leg disc morphogenesis GO:0007478 80 0.087
regulation of actin filament based process GO:0032970 42 0.087
Mouse
gliogenesis GO:0042063 80 0.087
Zebrafish Rat
carbohydrate metabolic process GO:0005975 82 0.085
sex differentiation GO:0007548 81 0.085
central nervous system development GO:0007417 201 0.084
determination of bilateral symmetry GO:0009855 13 0.083
ribonucleoside metabolic process GO:0009119 127 0.083
carbohydrate derivative biosynthetic process GO:1901137 85 0.082
Rat
response to organic substance GO:0010033 284 0.082
actin filament bundle assembly GO:0051017 26 0.081
salivary gland development GO:0007431 162 0.081
olfactory behavior GO:0042048 97 0.081
cellular response to growth factor stimulus GO:0071363 30 0.081
Human Mouse Rat
regulation of proteolysis GO:0030162 87 0.080
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.080
regulation of synapse organization GO:0050807 110 0.080
substrate adhesion dependent cell spreading GO:0034446 2 0.080
non sensory hair organization GO:0035316 47 0.080
regulation of catalytic activity GO:0050790 185 0.079
Human Mouse Rat
purine nucleotide metabolic process GO:0006163 146 0.079
glycosyl compound catabolic process GO:1901658 112 0.079
chemical homeostasis GO:0048878 92 0.078
Human Mouse
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.078
dna replication GO:0006260 48 0.078
Human
positive regulation of cell proliferation GO:0008284 47 0.077
Human Mouse Rat
dorsal ventral axis specification GO:0009950 66 0.076
regulation of cellular response to stress GO:0080135 89 0.076
Human
response to nitrogen compound GO:1901698 90 0.075
positive regulation of protein complex assembly GO:0031334 22 0.075
proteolysis GO:0006508 192 0.075
defense response to fungus GO:0050832 48 0.074
positive regulation of cellular component biogenesis GO:0044089 80 0.074
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.074
Mouse
developmental pigmentation GO:0048066 68 0.073
Zebrafish Mouse
regulation of autophagy GO:0010506 62 0.073
negative regulation of signal transduction GO:0009968 206 0.073
negative regulation of rna biosynthetic process GO:1902679 240 0.072
kidney development GO:0001822 3 0.072
Mouse Rat
pigment biosynthetic process GO:0046148 36 0.072
endomembrane system organization GO:0010256 119 0.071
purine nucleoside metabolic process GO:0042278 127 0.071
regulation of embryonic development GO:0045995 68 0.071
actin cytoskeleton reorganization GO:0031532 22 0.070
Human Mouse
initiation of dorsal closure GO:0007392 12 0.070
positive regulation of phosphate metabolic process GO:0045937 139 0.069
positive regulation of gene expression GO:0010628 290 0.069
Mouse
peripheral nervous system development GO:0007422 52 0.069
antibacterial humoral response GO:0019731 44 0.068
regulation of transport GO:0051049 181 0.068
Human Mouse
neuron recognition GO:0008038 101 0.068
multicellular organismal reproductive behavior GO:0033057 110 0.068
extrinsic apoptotic signaling pathway GO:0097191 1 0.068
ion transport GO:0006811 145 0.068
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.067
regulation of catabolic process GO:0009894 170 0.067
ribonucleoside triphosphate metabolic process GO:0009199 119 0.067
regulation of body fluid levels GO:0050878 14 0.066
Human
negative regulation of cellular metabolic process GO:0031324 382 0.066
negative regulation of biosynthetic process GO:0009890 277 0.066
cell type specific apoptotic process GO:0097285 38 0.066
Human Zebrafish
purine nucleotide catabolic process GO:0006195 109 0.066
regulation of lipid metabolic process GO:0019216 15 0.066
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.066
engulfment of apoptotic cell GO:0043652 6 0.065
regulation of cellular catabolic process GO:0031329 157 0.065
neuron death GO:0070997 27 0.064
positive regulation of transport GO:0051050 92 0.064
Human Mouse
regulation of cell cycle process GO:0010564 181 0.064
Mouse
regulation of cell cycle GO:0051726 291 0.064
Mouse
regeneration GO:0031099 16 0.064
regulation of organelle organization GO:0033043 196 0.064
Mouse
regulation of humoral immune response GO:0002920 51 0.064
pericardium development GO:0060039 2 0.063
defense response to virus GO:0051607 23 0.063
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.063
male gamete generation GO:0048232 201 0.063
Mouse
actomyosin structure organization GO:0031032 56 0.063
Mouse
outflow tract morphogenesis GO:0003151 4 0.062
eye development GO:0001654 323 0.062
Zebrafish Mouse
regulation of molecular function GO:0065009 217 0.062
Human Mouse Rat
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.062
organophosphate metabolic process GO:0019637 195 0.062
Human Mouse
organonitrogen compound catabolic process GO:1901565 128 0.062
mucopolysaccharide metabolic process GO:1903510 5 0.061
muscle tissue development GO:0060537 30 0.061
Mouse Rat
cellular response to lipopolysaccharide GO:0071222 3 0.061
organic cyclic compound catabolic process GO:1901361 168 0.061
anterior malpighian tubule development GO:0061327 12 0.060
positive regulation of immune response GO:0050778 63 0.060
cellular cation homeostasis GO:0030003 38 0.059
Human
purine containing compound catabolic process GO:0072523 112 0.059
photoreceptor cell development GO:0042461 96 0.059
macromolecular complex assembly GO:0065003 256 0.059
regulation of embryonic cell shape GO:0016476 30 0.058
maintenance of protein location GO:0045185 28 0.058
phosphorylation GO:0016310 294 0.058
glycosyl compound metabolic process GO:1901657 127 0.058
regulation of wnt signaling pathway GO:0030111 68 0.058
muscle structure development GO:0061061 224 0.058
Mouse Rat
positive regulation of signaling GO:0023056 243 0.058
positive regulation of macromolecule metabolic process GO:0010604 405 0.058
Human Mouse Rat
regulation of reproductive process GO:2000241 54 0.056
regulation of cell motility GO:2000145 23 0.056
Human Zebrafish Mouse Rat
reproductive behavior GO:0019098 122 0.056
specification of symmetry GO:0009799 13 0.055
phenol containing compound metabolic process GO:0018958 57 0.055
purine ribonucleoside metabolic process GO:0046128 127 0.055
calcium ion transport GO:0006816 24 0.055
Mouse
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.054
inorganic ion transmembrane transport GO:0098660 73 0.054
negative regulation of organelle organization GO:0010639 56 0.054
imaginal disc derived appendage development GO:0048737 399 0.054
signal transduction by phosphorylation GO:0023014 107 0.054
cellular chemical homeostasis GO:0055082 40 0.053
Human
glial cell migration GO:0008347 31 0.053
regulation of cell migration GO:0030334 22 0.053
Human Zebrafish Mouse Rat
regulation of erbb signaling pathway GO:1901184 42 0.052
positive regulation of neurogenesis GO:0050769 41 0.052
cortical cytoskeleton organization GO:0030865 29 0.052
regionalization GO:0003002 416 0.052
motor neuron axon guidance GO:0008045 58 0.051
negative regulation of neuron death GO:1901215 18 0.051
chemosensory behavior GO:0007635 106 0.051
gland morphogenesis GO:0022612 145 0.051
response to reactive oxygen species GO:0000302 24 0.051
Rat
regulation of antifungal peptide production GO:0002788 6 0.050
regulation of neuron projection development GO:0010975 69 0.050
renal filtration GO:0097205 7 0.050
regulation of carbohydrate metabolic process GO:0006109 10 0.050
nucleoside triphosphate metabolic process GO:0009141 120 0.049
cation transport GO:0006812 110 0.049
Mouse
regulation of innate immune response GO:0045088 71 0.049
response to ethanol GO:0045471 59 0.049
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.049
response to transforming growth factor beta GO:0071559 18 0.049
adherens junction assembly GO:0034333 11 0.049
Human
negative regulation of rna metabolic process GO:0051253 251 0.048
regulation of axonogenesis GO:0050770 32 0.048
regulation of cell adhesion GO:0030155 27 0.048
Human
positive regulation of lipid metabolic process GO:0045834 4 0.047
Human
histone modification GO:0016570 106 0.047
mesoderm development GO:0007498 78 0.047
organic acid metabolic process GO:0006082 103 0.047
actin cytoskeleton organization GO:0030036 206 0.047
regulation of tube size GO:0035150 46 0.047
response to oxidative stress GO:0006979 86 0.047
Rat
regulation of cellular amine metabolic process GO:0033238 3 0.047
tissue morphogenesis GO:0048729 297 0.047
gastrulation with mouth forming first GO:0001703 36 0.047
amine metabolic process GO:0009308 12 0.047
regulation of protein localization GO:0032880 76 0.046
Human
regulation of cellular localization GO:0060341 136 0.046
Human
regulation of stress activated mapk cascade GO:0032872 41 0.046
Human
establishment of protein localization GO:0045184 163 0.046
Human
skin development GO:0043588 65 0.046
macromolecule catabolic process GO:0009057 161 0.046
cellular response to external stimulus GO:0071496 66 0.046
negative regulation of response to external stimulus GO:0032102 22 0.046
Human
response to radiation GO:0009314 155 0.046
Mouse
cellular macromolecule localization GO:0070727 220 0.045
negative regulation of mitotic cell cycle GO:0045930 109 0.045
nucleoside phosphate catabolic process GO:1901292 110 0.045
connective tissue development GO:0061448 3 0.045
Mouse
meiotic cell cycle GO:0051321 171 0.045
wound healing GO:0042060 75 0.045
Human Mouse Rat
cellular component disassembly GO:0022411 46 0.045
purine nucleoside triphosphate metabolic process GO:0009144 119 0.045
lipid metabolic process GO:0006629 121 0.044
Human Mouse
positive regulation of cell motility GO:2000147 3 0.044
Human Zebrafish Mouse Rat
regulation of actin cytoskeleton organization GO:0032956 42 0.044
Mouse
regulation of cell substrate adhesion GO:0010810 2 0.044
Human
chorion containing eggshell formation GO:0007304 105 0.044
response to hydrogen peroxide GO:0042542 11 0.044
Rat
axis specification GO:0009798 167 0.044
skeletal muscle fiber development GO:0048741 3 0.044
regulation of programmed cell death GO:0043067 152 0.043
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.043
Human Mouse
regulation of multivesicular body size involved in endosome transport GO:0010797 2 0.043
cellular response to dna damage stimulus GO:0006974 223 0.043
carbohydrate derivative catabolic process GO:1901136 118 0.043
vesicle organization GO:0016050 44 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.042
response to lipopolysaccharide GO:0032496 4 0.042
regulation of vesicle mediated transport GO:0060627 59 0.041
cell maturation GO:0048469 144 0.041
Mouse
regulation of antimicrobial peptide production GO:0002784 44 0.041
regulation of localization GO:0032879 275 0.041
Human Zebrafish Mouse Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.041
cortical actin cytoskeleton organization GO:0030866 24 0.041
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.041
encapsulation of foreign target GO:0035010 38 0.041
regulation of multicellular organism growth GO:0040014 40 0.041
positive regulation of catalytic activity GO:0043085 118 0.040
Human Mouse Rat
sex determination GO:0007530 18 0.040
positive regulation of axonogenesis GO:0050772 2 0.040
determination of left right symmetry GO:0007368 9 0.040
positive regulation of protein deacetylation GO:0090312 2 0.040
dorsal closure spreading of leading edge cells GO:0007395 4 0.040
single organism behavior GO:0044708 391 0.040
pigmentation GO:0043473 75 0.040
Zebrafish Mouse
camera type eye development GO:0043010 4 0.040
Zebrafish Mouse
stress activated mapk cascade GO:0051403 52 0.039
Human
renal tubule morphogenesis GO:0061333 44 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.039
positive regulation of neuron differentiation GO:0045666 26 0.039
stem cell development GO:0048864 79 0.038
synaptic growth at neuromuscular junction GO:0051124 119 0.038

Pvr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.166
Human
disease of cellular proliferation DOID:14566 0 0.115
Human
cancer DOID:162 0 0.096
Human
organ system cancer DOID:0050686 0 0.096
Human