Drosophila melanogaster

66 known processes

otu (Dmel_CG12743)

ovarian tumor

(Aliases: fs(1)jA265,K,fs(1)23l,DROOTUA,OTU,fs(1)231,fs(1)M101,fs(1)otu,Dmel\CG12743,Otu,CG12743)

otu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell development GO:0030707 248 0.998
chorion containing eggshell formation GO:0007304 105 0.930
dna packaging GO:0006323 91 0.921
eggshell formation GO:0030703 105 0.913
pirna metabolic process GO:0034587 10 0.831
germarium derived egg chamber formation GO:0007293 101 0.817
vitelline membrane formation involved in chorion containing eggshell formation GO:0007305 11 0.814
cell migration GO:0016477 238 0.776
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.723
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.667
dorsal appendage formation GO:0046843 47 0.626
germarium derived oocyte fate determination GO:0007294 26 0.615
epithelium migration GO:0090132 148 0.562
chromosome condensation GO:0030261 41 0.558
muscle structure development GO:0061061 224 0.555
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.554
cell division GO:0051301 248 0.543
cell motility GO:0048870 251 0.541
germarium derived oocyte differentiation GO:0030706 29 0.529
negative regulation of biosynthetic process GO:0009890 277 0.517
ovarian fusome organization GO:0030723 11 0.495
oocyte maturation GO:0001556 3 0.489
digestive tract development GO:0048565 149 0.484
dna conformation change GO:0071103 105 0.431
regulation of gene expression epigenetic GO:0040029 128 0.425
negative regulation of cellular metabolic process GO:0031324 382 0.423
male gamete generation GO:0048232 201 0.404
negative regulation of gene expression GO:0010629 387 0.402
taxis GO:0042330 304 0.396
epithelial cell development GO:0002064 274 0.374
tissue migration GO:0090130 155 0.369
posttranscriptional regulation of gene expression GO:0010608 145 0.355
negative regulation of cellular biosynthetic process GO:0031327 277 0.320
eggshell chorion assembly GO:0007306 66 0.310
chromosome organization GO:0051276 360 0.308
epithelial cell migration GO:0010631 148 0.304
regulation of localization GO:0032879 275 0.297
negative regulation of transposition GO:0010529 12 0.284
oocyte construction GO:0007308 112 0.283
spermatogenesis GO:0007283 200 0.273
regulation of oocyte development GO:0060281 27 0.271
rna processing GO:0006396 147 0.258
stem cell maintenance GO:0019827 67 0.255
adult behavior GO:0030534 137 0.253
tube morphogenesis GO:0035239 191 0.233
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.225
ncrna metabolic process GO:0034660 43 0.225
digestive tract morphogenesis GO:0048546 127 0.220
ameboidal type cell migration GO:0001667 151 0.219
organelle assembly GO:0070925 198 0.212
epithelial cell differentiation GO:0030855 322 0.202
gene silencing GO:0016458 138 0.198
mitotic chromosome condensation GO:0007076 22 0.194
regulation of cellular protein metabolic process GO:0032268 243 0.187
female germ line stem cell asymmetric division GO:0048132 14 0.186
morphogenesis of an epithelium GO:0002009 276 0.173
oocyte anterior posterior axis specification GO:0007314 72 0.173
mrna processing GO:0006397 104 0.162
stem cell development GO:0048864 79 0.160
oocyte development GO:0048599 124 0.158
response to other organism GO:0051707 293 0.146
sex differentiation GO:0007548 81 0.143
localization of cell GO:0051674 257 0.141
meiotic nuclear division GO:0007126 151 0.134
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.132
muscle cell differentiation GO:0042692 103 0.131
negative regulation of transcription dna templated GO:0045892 237 0.130
organelle fission GO:0048285 340 0.128
terminal region determination GO:0007362 25 0.126
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.121
oocyte dorsal ventral axis specification GO:0007310 34 0.118
chromatin organization GO:0006325 207 0.118
mrna metabolic process GO:0016071 124 0.117
regulation of meiosis GO:0040020 3 0.115
oocyte axis specification GO:0007309 108 0.115
pole plasm mrna localization GO:0019094 49 0.114
columnar cuboidal epithelial cell development GO:0002066 249 0.111
gene silencing by rna GO:0031047 57 0.111
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.110
cell maturation GO:0048469 144 0.101
fusome organization GO:0045478 13 0.101
female germ line cyst formation GO:0048135 42 0.097
positive regulation of biosynthetic process GO:0009891 316 0.097
negative regulation of rna biosynthetic process GO:1902679 240 0.096
digestive system development GO:0055123 149 0.093
oocyte differentiation GO:0009994 145 0.092
embryonic pattern specification GO:0009880 174 0.092
regulation of rna splicing GO:0043484 69 0.092
positive regulation of signal transduction GO:0009967 223 0.090
associative learning GO:0008306 65 0.090
programmed cell death GO:0012501 257 0.087
positive regulation of response to stimulus GO:0048584 323 0.087
positive regulation of macromolecule metabolic process GO:0010604 405 0.086
germ line stem cell division GO:0042078 25 0.085
negative regulation of nucleic acid templated transcription GO:1903507 240 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.084
regulation of protein metabolic process GO:0051246 256 0.082
amine metabolic process GO:0009308 12 0.082
dendrite development GO:0016358 204 0.081
regulation of cell cycle GO:0051726 291 0.080
regulation of mrna processing GO:0050684 71 0.080
positive regulation of protein metabolic process GO:0051247 128 0.079
nurse cell apoptotic process GO:0045476 17 0.079
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.079
transposition GO:0032196 13 0.078
reproductive structure development GO:0048608 74 0.076
positive regulation of rna metabolic process GO:0051254 271 0.076
defense response to bacterium GO:0042742 178 0.073
cellular component assembly involved in morphogenesis GO:0010927 151 0.073
dna methylation GO:0006306 4 0.072
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.072
ovarian nurse cell to oocyte transport GO:0007300 27 0.072
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.071
regulation of transmembrane transport GO:0034762 27 0.070
death GO:0016265 284 0.070
dna metabolic process GO:0006259 227 0.070
tube development GO:0035295 244 0.069
reproductive system development GO:0061458 74 0.069
regulation of mrna metabolic process GO:1903311 72 0.069
positive regulation of cellular protein metabolic process GO:0032270 118 0.068
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.068
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.068
positive regulation of gene expression GO:0010628 290 0.066
negative regulation of protein depolymerization GO:1901880 23 0.063
chitin based cuticle development GO:0040003 49 0.063
regulation of nervous system development GO:0051960 248 0.062
regulation of cell cycle process GO:0010564 181 0.061
pole plasm protein localization GO:0007318 10 0.061
myofibril assembly GO:0030239 36 0.060
regulation of anatomical structure morphogenesis GO:0022603 242 0.059
egg coat formation GO:0035803 11 0.059
muscle cell development GO:0055001 50 0.059
positive regulation of cellular biosynthetic process GO:0031328 316 0.058
regulation of chromatin silencing GO:0031935 36 0.058
positive regulation of signaling GO:0023056 243 0.057
oocyte fate determination GO:0030716 27 0.056
striated muscle cell development GO:0055002 50 0.056
posttranscriptional gene silencing GO:0016441 46 0.056
phosphorylation GO:0016310 294 0.056
cystoblast division GO:0007282 10 0.055
positive regulation of mrna metabolic process GO:1903313 5 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.054
regulation of cell division GO:0051302 72 0.053
positive regulation of translation GO:0045727 12 0.052
anterior posterior pattern specification GO:0009952 136 0.052
regulation of multi organism process GO:0043900 131 0.052
synaptic transmission GO:0007268 288 0.052
translation GO:0006412 69 0.051
negative regulation of gene expression epigenetic GO:0045814 77 0.051
response to bacterium GO:0009617 198 0.050
germ line stem cell maintenance GO:0030718 50 0.050
cellular response to extracellular stimulus GO:0031668 64 0.049
lateral inhibition GO:0046331 206 0.049
regulation of cellular amine metabolic process GO:0033238 3 0.047
embryonic axis specification GO:0000578 107 0.046
regulation of growth GO:0040008 233 0.046
chromatin silencing GO:0006342 76 0.046
transmembrane transport GO:0055085 139 0.046
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.045
enzyme linked receptor protein signaling pathway GO:0007167 179 0.045
stem cell differentiation GO:0048863 117 0.045
nuclear division GO:0000280 332 0.045
segmentation GO:0035282 207 0.045
developmental maturation GO:0021700 172 0.044
protein dna complex subunit organization GO:0071824 86 0.044
camera type eye development GO:0043010 4 0.043
cellular amine metabolic process GO:0044106 12 0.043
negative regulation of protein metabolic process GO:0051248 85 0.042
negative regulation of rna metabolic process GO:0051253 251 0.041
spindle organization GO:0007051 253 0.041
gonad development GO:0008406 50 0.041
spermatid development GO:0007286 98 0.041
posttranscriptional gene silencing by rna GO:0035194 45 0.040
immune system process GO:0002376 347 0.039
negative regulation of cellular protein metabolic process GO:0032269 85 0.039
learning or memory GO:0007611 141 0.039
polarity specification of dorsal ventral axis GO:0009951 6 0.039
spermatid differentiation GO:0048515 114 0.039
regulation of immune response GO:0050776 118 0.038
regulation of intracellular signal transduction GO:1902531 236 0.038
positive regulation of developmental process GO:0051094 143 0.038
regulation of protein complex disassembly GO:0043244 29 0.038
regulation of cell development GO:0060284 215 0.038
wing disc morphogenesis GO:0007472 344 0.038
anatomical structure homeostasis GO:0060249 97 0.037
development of primary sexual characteristics GO:0045137 50 0.037
positive regulation of nucleic acid templated transcription GO:1903508 266 0.036
response to temperature stimulus GO:0009266 106 0.036
dna geometric change GO:0032392 16 0.036
microtubule organizing center organization GO:0031023 168 0.035
germarium derived female germ line cyst formation GO:0030727 42 0.035
compound eye morphogenesis GO:0001745 249 0.035
tripartite regional subdivision GO:0007351 103 0.035
protein modification process GO:0036211 438 0.035
axis specification GO:0009798 167 0.035
cellular response to nitrogen compound GO:1901699 51 0.035
sex determination GO:0007530 18 0.034
cellular amino acid metabolic process GO:0006520 61 0.034
intracellular mrna localization GO:0008298 66 0.034
anterior posterior axis specification embryo GO:0008595 103 0.034
vesicle mediated transport GO:0016192 381 0.033
actin cytoskeleton organization GO:0030036 206 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
apoptotic process GO:0006915 159 0.033
regulation of transcription by chromatin organization GO:0034401 3 0.032
positive regulation of cell communication GO:0010647 250 0.032
muscle organ development GO:0007517 127 0.032
morphogenesis of follicular epithelium GO:0016333 36 0.032
striated muscle cell differentiation GO:0051146 90 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
dendrite morphogenesis GO:0048813 199 0.031
positive regulation of mitotic cell cycle GO:0045931 34 0.030
actin filament based process GO:0030029 220 0.030
mrna splicing via spliceosome GO:0000398 73 0.030
negative regulation of oskar mrna translation GO:0007319 5 0.030
regulation of transposition GO:0010528 13 0.030
regulation of translation GO:0006417 56 0.030
regulation of cell differentiation GO:0045595 302 0.030
rna interference GO:0016246 27 0.030
cellular protein modification process GO:0006464 438 0.030
single organismal cell cell adhesion GO:0016337 45 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
maternal determination of anterior posterior axis embryo GO:0008358 74 0.029
developmental growth GO:0048589 280 0.029
intercellular transport GO:0010496 2 0.029
central nervous system development GO:0007417 201 0.029
single organism behavior GO:0044708 391 0.029
regulation of mitotic cell cycle GO:0007346 190 0.028
regulation of cellular localization GO:0060341 136 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.028
heterochromatin organization GO:0070828 25 0.028
germ line cyst formation GO:0048134 44 0.028
neurological system process GO:0050877 358 0.028
pole plasm assembly GO:0007315 61 0.028
anterior posterior axis specification GO:0009948 109 0.027
tissue morphogenesis GO:0048729 297 0.027
regulation of mrna splicing via spliceosome GO:0048024 64 0.027
karyosome formation GO:0030717 22 0.027
regulation of phosphorylation GO:0042325 147 0.027
positive regulation of mrna catabolic process GO:0061014 5 0.027
immune response GO:0006955 246 0.027
regulation of transport GO:0051049 181 0.027
cellular ketone metabolic process GO:0042180 24 0.026
germline stem cell asymmetric division GO:0098728 15 0.026
stem cell division GO:0017145 69 0.026
intracellular signal transduction GO:0035556 300 0.026
cell death GO:0008219 279 0.026
defense response to other organism GO:0098542 225 0.025
response to organic substance GO:0010033 284 0.024
regulation of microtubule cytoskeleton organization GO:0070507 41 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
response to heat GO:0009408 63 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
rna localization GO:0006403 115 0.023
regulation of organelle organization GO:0033043 196 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
organic acid metabolic process GO:0006082 103 0.023
cuticle development GO:0042335 86 0.023
appendage morphogenesis GO:0035107 397 0.023
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.022
endodermal cell fate commitment GO:0001711 3 0.022
negative regulation of protein complex disassembly GO:0043242 23 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
rna 3 end processing GO:0031123 45 0.022
cell fate specification GO:0001708 71 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
mrna catabolic process GO:0006402 33 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
germarium derived female germ line cyst encapsulation GO:0030708 8 0.021
dna alkylation GO:0006305 4 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
regionalization GO:0003002 416 0.021
eye morphogenesis GO:0048592 260 0.021
alternative mrna splicing via spliceosome GO:0000380 60 0.021
appendage development GO:0048736 401 0.021
axon development GO:0061564 297 0.021
negative regulation of organelle organization GO:0010639 56 0.020
molting cycle GO:0042303 56 0.020
negative regulation of cell communication GO:0010648 223 0.020
negative regulation of developmental process GO:0051093 201 0.020
aggressive behavior GO:0002118 63 0.020
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.020
actin filament organization GO:0007015 126 0.020
axonogenesis GO:0007409 290 0.020
regulation of nuclear division GO:0051783 58 0.020
compound eye photoreceptor cell differentiation GO:0001751 140 0.020
mesenchymal cell development GO:0014031 1 0.020
regulation of embryonic development GO:0045995 68 0.020
cation transport GO:0006812 110 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
genital disc development GO:0035215 44 0.020
cell projection assembly GO:0030031 94 0.019
multicellular organism growth GO:0035264 46 0.019
regulation of developmental growth GO:0048638 174 0.019
epithelial cell migration open tracheal system GO:0007427 32 0.019
nuclear dna replication GO:0033260 1 0.019
blastoderm segmentation GO:0007350 159 0.019
regulation of transposition rna mediated GO:0010525 3 0.019
regulation of gene silencing GO:0060968 63 0.018
lipid localization GO:0010876 54 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
peptidyl amino acid modification GO:0018193 105 0.018
multi multicellular organism process GO:0044706 123 0.018
single organism cellular localization GO:1902580 180 0.018
response to external biotic stimulus GO:0043207 293 0.017
secretion GO:0046903 109 0.017
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.017
open tracheal system development GO:0007424 204 0.017
positive regulation of developmental growth GO:0048639 62 0.017
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.017
morphogenesis of a branching structure GO:0001763 45 0.017
dorsal ventral axis specification GO:0009950 66 0.017
regulation of cell maturation GO:1903429 27 0.016
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.016
negative regulation of signal transduction GO:0009968 206 0.016
mrna 3 end processing GO:0031124 28 0.016
instar larval development GO:0002168 55 0.016
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.016
somatic muscle development GO:0007525 66 0.016
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
small molecule biosynthetic process GO:0044283 37 0.016
respiratory system development GO:0060541 213 0.016
regulation of catalytic activity GO:0050790 185 0.016
erbb signaling pathway GO:0038127 58 0.016
photoreceptor cell differentiation GO:0046530 170 0.015
negative regulation of translation GO:0017148 28 0.015
oocyte microtubule cytoskeleton organization GO:0016325 35 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
mitotic nuclear division GO:0007067 213 0.015
fertilization GO:0009566 26 0.015
response to wounding GO:0009611 94 0.015
endocytosis GO:0006897 310 0.015
chromatin assembly or disassembly GO:0006333 52 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
regulation of reproductive process GO:2000241 54 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
regulation of anatomical structure size GO:0090066 163 0.015
positive regulation of protein transport GO:0051222 37 0.014
cognition GO:0050890 141 0.014
chromatin assembly GO:0031497 48 0.014
eye photoreceptor cell development GO:0042462 81 0.014
multi organism reproductive behavior GO:0044705 121 0.014
gland morphogenesis GO:0022612 145 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
macromolecule methylation GO:0043414 45 0.014
jak stat cascade GO:0007259 49 0.014
response to oxygen containing compound GO:1901700 200 0.014
regulation of programmed cell death GO:0043067 152 0.014
ovarian follicle cell stalk formation GO:0030713 17 0.014
sister chromatid segregation GO:0000819 92 0.014
pole plasm rna localization GO:0007316 52 0.013
establishment of localization in cell GO:0051649 402 0.013
small molecule metabolic process GO:0044281 305 0.013
response to hypoxia GO:0001666 53 0.013
positive regulation of nervous system development GO:0051962 69 0.013
cellular response to hypoxia GO:0071456 28 0.013
regulation of response to stress GO:0080134 200 0.013
male meiosis GO:0007140 52 0.013
connective tissue development GO:0061448 3 0.013
oxoacid metabolic process GO:0043436 103 0.013
genitalia development GO:0048806 26 0.013
wound healing GO:0042060 75 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
asymmetric cell division GO:0008356 37 0.013
mitotic spindle organization GO:0007052 220 0.013
chromosome segregation GO:0007059 157 0.013
border follicle cell migration GO:0007298 113 0.013
cell fate determination GO:0001709 91 0.013
germline ring canal formation GO:0030725 13 0.013
imaginal disc derived wing vein specification GO:0007474 48 0.012
regulation of protein catabolic process GO:0042176 55 0.012
regulation of protein localization GO:0032880 76 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
regulation of multicellular organism growth GO:0040014 40 0.012
olfactory learning GO:0008355 56 0.012
single organism biosynthetic process GO:0044711 206 0.012
rna catabolic process GO:0006401 37 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
rna splicing GO:0008380 83 0.012
multicellular organismal aging GO:0010259 140 0.012
regulation of defense response GO:0031347 102 0.012
meiotic cell cycle process GO:1903046 132 0.012
salivary gland development GO:0007431 162 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
eye development GO:0001654 323 0.012
foregut morphogenesis GO:0007440 10 0.012
positive regulation of cell cycle process GO:0090068 28 0.012
long term memory GO:0007616 62 0.012
protein secretion GO:0009306 45 0.011
phagocytosis GO:0006909 215 0.011
regulation of immune system process GO:0002682 176 0.011
dna methylation or demethylation GO:0044728 4 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
positive regulation of protein import into nucleus GO:0042307 21 0.011
mesoderm development GO:0007498 78 0.011
chaeta morphogenesis GO:0008407 42 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
negative regulation of peptide hormone secretion GO:0090278 1 0.011
gastrulation with mouth forming first GO:0001703 36 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
chromatin modification GO:0016568 147 0.011
regulation of microtubule based process GO:0032886 49 0.011
imaginal disc pattern formation GO:0007447 91 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
negative regulation of cell cycle GO:0045786 116 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
circulatory system process GO:0003013 37 0.011
regulation of ion transmembrane transport GO:0034765 27 0.011
protein phosphorylation GO:0006468 169 0.011
microtubule anchoring GO:0034453 11 0.011
homeostatic process GO:0042592 199 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
dna modification GO:0006304 5 0.011
secretion by cell GO:0032940 101 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
positive regulation of growth GO:0045927 75 0.011
nuclear transport GO:0051169 72 0.010
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.010
cellular response to decreased oxygen levels GO:0036294 30 0.010
regulation of hormone levels GO:0010817 40 0.010
inter male aggressive behavior GO:0002121 60 0.010
vesicle localization GO:0051648 55 0.010
positive regulation of defense response GO:0031349 59 0.010
aromatic compound catabolic process GO:0019439 166 0.010
lipid biosynthetic process GO:0008610 46 0.010

otu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.084
artery disease DOID:0050828 0 0.084
disease of anatomical entity DOID:7 0 0.084
vascular disease DOID:178 0 0.084
essential hypertension DOID:10825 0 0.084
cardiovascular system disease DOID:1287 0 0.084