Drosophila melanogaster

0 known processes

ClC-c (Dmel_CG5284)

Chloride channel-c

(Aliases: DmClCc,anon-WO0138359.7,DmClC-c,CG5284,Dmel\CG5284)

ClC-c biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
inorganic cation transmembrane transport GO:0098662 61 0.216
ion transmembrane transport GO:0034220 122 0.213
Human Rat
transmembrane transport GO:0055085 139 0.199
Human Rat
cation transmembrane transport GO:0098655 88 0.153
ion transport GO:0006811 145 0.133
Human Rat
tube morphogenesis GO:0035239 191 0.111
response to external biotic stimulus GO:0043207 293 0.096
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.078
cation transport GO:0006812 110 0.076
inorganic ion transmembrane transport GO:0098660 73 0.075
Human Rat
macromolecular complex assembly GO:0065003 256 0.073
metal ion transport GO:0030001 74 0.071
localization of cell GO:0051674 257 0.071
organic acid metabolic process GO:0006082 103 0.068
small molecule metabolic process GO:0044281 305 0.058
peptidyl amino acid modification GO:0018193 105 0.058
phosphorylation GO:0016310 294 0.056
negative regulation of response to stimulus GO:0048585 258 0.055
cell migration GO:0016477 238 0.053
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
cellular response to dna damage stimulus GO:0006974 223 0.050
cellular macromolecular complex assembly GO:0034622 153 0.049
cellular ketone metabolic process GO:0042180 24 0.049
monovalent inorganic cation transport GO:0015672 40 0.048
negative regulation of cell communication GO:0010648 223 0.047
catabolic process GO:0009056 409 0.045
positive regulation of biosynthetic process GO:0009891 316 0.044
oxoacid metabolic process GO:0043436 103 0.044
response to abiotic stimulus GO:0009628 341 0.043
regulation of localization GO:0032879 275 0.043
Rat
blastoderm segmentation GO:0007350 159 0.042
cellular response to chemical stimulus GO:0070887 199 0.042
protein modification process GO:0036211 438 0.042
negative regulation of cellular biosynthetic process GO:0031327 277 0.042
sodium ion transport GO:0006814 22 0.041
forebrain development GO:0030900 2 0.039
protein complex biogenesis GO:0070271 201 0.038
organic substance catabolic process GO:1901575 308 0.038
intracellular transport GO:0046907 228 0.038
response to oxygen containing compound GO:1901700 200 0.038
response to other organism GO:0051707 293 0.038
response to organic substance GO:0010033 284 0.037
immune response regulating signaling pathway GO:0002764 2 0.037
organic substance transport GO:0071702 257 0.034
chromosome organization GO:0051276 360 0.034
single organism membrane organization GO:0044802 93 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
carboxylic acid metabolic process GO:0019752 92 0.033
lipid metabolic process GO:0006629 121 0.032
protein complex assembly GO:0006461 200 0.032
response to bacterium GO:0009617 198 0.031
regulation of cellular amine metabolic process GO:0033238 3 0.031
cellular amine metabolic process GO:0044106 12 0.031
protein localization GO:0008104 284 0.031
single organism membrane fusion GO:0044801 42 0.030
organelle fusion GO:0048284 46 0.030
cell motility GO:0048870 251 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
membrane organization GO:0061024 112 0.029
synaptic transmission GO:0007268 288 0.029
regulation of insulin receptor signaling pathway GO:0046626 17 0.029
regulation of immune response GO:0050776 118 0.029
immune system process GO:0002376 347 0.028
lipid localization GO:0010876 54 0.027
organophosphate metabolic process GO:0019637 195 0.027
protein acetylation GO:0006473 39 0.027
negative regulation of signal transduction GO:0009968 206 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
positive regulation of response to stimulus GO:0048584 323 0.027
histone modification GO:0016570 106 0.026
regulation of cellular component movement GO:0051270 42 0.026
regulation of cellular response to growth factor stimulus GO:0090287 13 0.026
regulation of cellular ketone metabolic process GO:0010565 3 0.026
response to biotic stimulus GO:0009607 294 0.026
neurological system process GO:0050877 358 0.026
Fly
positive regulation of lipid biosynthetic process GO:0046889 3 0.025
head development GO:0060322 135 0.025
cell recognition GO:0008037 102 0.025
gastrulation GO:0007369 70 0.025
death GO:0016265 284 0.025
developmental growth GO:0048589 280 0.025
telencephalon development GO:0021537 2 0.024
positive regulation of cell motility GO:2000147 3 0.024
axonogenesis GO:0007409 290 0.024
cellular lipid metabolic process GO:0044255 83 0.024
immune response GO:0006955 246 0.024
regulation of transmembrane transport GO:0034762 27 0.024
Rat
cellular response to organic substance GO:0071310 132 0.023
growth GO:0040007 359 0.023
g2 dna damage checkpoint GO:0031572 69 0.023
cellular catabolic process GO:0044248 372 0.023
single organism biosynthetic process GO:0044711 206 0.023
synaptic target recognition GO:0008039 45 0.023
immune response activating signal transduction GO:0002757 2 0.022
apoptotic process GO:0006915 159 0.022
segmentation GO:0035282 207 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
limb development GO:0060173 1 0.022
anterior posterior pattern specification GO:0009952 136 0.022
digestive tract morphogenesis GO:0048546 127 0.022
negative regulation of phosphatase activity GO:0010923 3 0.021
brain development GO:0007420 120 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
body morphogenesis GO:0010171 2 0.021
endomembrane system organization GO:0010256 119 0.021
very long chain fatty acid catabolic process GO:0042760 2 0.021
lipid modification GO:0030258 24 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
regionalization GO:0003002 416 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
heparin metabolic process GO:0030202 4 0.021
store operated calcium entry GO:0002115 3 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.020
positive regulation of lipid metabolic process GO:0045834 4 0.020
regulation of multi organism process GO:0043900 131 0.020
limb morphogenesis GO:0035108 1 0.020
modification dependent protein catabolic process GO:0019941 78 0.020
vesicle targeting to from or within golgi GO:0048199 1 0.020
centrosome organization GO:0051297 163 0.020
chromatin modification GO:0016568 147 0.019
regulation of steroid metabolic process GO:0019218 2 0.019
spindle organization GO:0007051 253 0.019
response to glucose GO:0009749 2 0.019
amine metabolic process GO:0009308 12 0.018
neuron recognition GO:0008038 101 0.018
negative regulation of gene expression GO:0010629 387 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
cell fate specification GO:0001708 71 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
chondroitin sulfate biosynthetic process GO:0030206 2 0.018
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.018
macromolecule catabolic process GO:0009057 161 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.018
monocarboxylic acid transport GO:0015718 3 0.017
intracellular signal transduction GO:0035556 300 0.017
regulation of ion transport GO:0043269 39 0.017
Rat
cell proliferation GO:0008283 299 0.017
positive regulation of synapse assembly GO:0051965 29 0.017
response to growth factor GO:0070848 31 0.017
muscle structure development GO:0061061 224 0.017
epithelial cell differentiation GO:0030855 322 0.017
cellular protein modification process GO:0006464 438 0.017
protein phosphorylation GO:0006468 169 0.017
negative regulation of signaling GO:0023057 219 0.017
single organism intracellular transport GO:1902582 207 0.016
imaginal disc pattern formation GO:0007447 91 0.016
regulation of hemocyte proliferation GO:0035206 37 0.016
regulation of cell differentiation GO:0045595 302 0.016
aromatic compound catabolic process GO:0019439 166 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
sensory perception of mechanical stimulus GO:0050954 72 0.016
Fly
tripartite regional subdivision GO:0007351 103 0.016
heart development GO:0007507 82 0.016
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.016
axon development GO:0061564 297 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
neuron projection guidance GO:0097485 241 0.015
ameboidal type cell migration GO:0001667 151 0.015
tissue migration GO:0090130 155 0.015
positive regulation of signal transduction GO:0009967 223 0.015
lysosomal transport GO:0007041 13 0.015
circulatory system development GO:0072359 82 0.015
actin filament based process GO:0030029 220 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
nuclear division GO:0000280 332 0.015
divalent metal ion transport GO:0070838 26 0.015
protein transport GO:0015031 155 0.015
tube development GO:0035295 244 0.014
regulation of cellular component size GO:0032535 98 0.014
protein transmembrane transport GO:0071806 4 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
response to insulin GO:0032868 29 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of response to external stimulus GO:0032101 115 0.014
nephron development GO:0072006 3 0.014
monocarboxylic acid metabolic process GO:0032787 29 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
carbohydrate metabolic process GO:0005975 82 0.014
potassium ion transport GO:0006813 20 0.014
positive regulation of cell communication GO:0010647 250 0.014
cellular protein localization GO:0034613 160 0.014
positive regulation of immune system process GO:0002684 68 0.014
regulation of cell morphogenesis GO:0022604 163 0.014
divalent inorganic cation transport GO:0072511 30 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
activation of innate immune response GO:0002218 4 0.014
negative regulation of immune system process GO:0002683 50 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
response to peptide GO:1901652 29 0.014
nephron tubule development GO:0072080 3 0.014
organic acid transport GO:0015849 18 0.013
positive regulation of transport GO:0051050 92 0.013
response to organic cyclic compound GO:0014070 89 0.013
anion transport GO:0006820 41 0.013
Human Rat
defense response GO:0006952 300 0.013
central nervous system development GO:0007417 201 0.013
chromatin organization GO:0006325 207 0.013
gland development GO:0048732 191 0.013
axon guidance GO:0007411 233 0.013
cellular response to growth factor stimulus GO:0071363 30 0.013
kidney epithelium development GO:0072073 3 0.013
establishment of protein localization GO:0045184 163 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regulation of cell proliferation GO:0042127 163 0.012
cardiovascular system development GO:0072358 82 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
defense response to bacterium GO:0042742 178 0.012
chemotaxis GO:0006935 249 0.012
defense response to other organism GO:0098542 225 0.012
golgi organization GO:0007030 66 0.012
cell death GO:0008219 279 0.012
kidney development GO:0001822 3 0.012
sulfur compound biosynthetic process GO:0044272 16 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.012
positive regulation of cell size GO:0045793 21 0.012
positive regulation of cell migration GO:0030335 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of cellular response to stress GO:0080135 89 0.012
regulation of immune system process GO:0002682 176 0.012
regulation of anatomical structure size GO:0090066 163 0.012
organelle localization GO:0051640 148 0.012
cellularization GO:0007349 90 0.012
response to lipopolysaccharide GO:0032496 4 0.011
neuromuscular junction development GO:0007528 149 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
innate immune response GO:0045087 144 0.011
membrane fusion GO:0061025 42 0.011
cellular response to peptide hormone stimulus GO:0071375 28 0.011
epithelium migration GO:0090132 148 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
ras protein signal transduction GO:0007265 88 0.011
multicellular organismal aging GO:0010259 140 0.011
axis specification GO:0009798 167 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
digestive system development GO:0055123 149 0.011
meiotic cell cycle GO:0051321 171 0.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.011
smoothened signaling pathway GO:0007224 49 0.011
regulation of growth GO:0040008 233 0.011
response to hexose GO:0009746 3 0.011
meiotic nuclear division GO:0007126 151 0.011
regulation of phosphatase activity GO:0010921 3 0.011
maintenance of location GO:0051235 73 0.011
regulation of phagocytosis engulfment GO:0060099 1 0.010
oxidation reduction process GO:0055114 123 0.010
taxis GO:0042330 304 0.010
larval locomotory behavior GO:0008345 27 0.010
response to monosaccharide GO:0034284 4 0.010
regulation of protein metabolic process GO:0051246 256 0.010
connective tissue development GO:0061448 3 0.010
synapse organization GO:0050808 196 0.010
organelle fission GO:0048285 340 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
sensory organ morphogenesis GO:0090596 260 0.010
embryonic pattern specification GO:0009880 174 0.010
positive regulation of calcium ion transport GO:0051928 4 0.010

ClC-c disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
sensory system disease DOID:0050155 0 0.025
nervous system disease DOID:863 0 0.025
vascular disease DOID:178 0 0.015
cardiovascular system disease DOID:1287 0 0.015
bone disease DOID:0080001 0 0.014
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012