Drosophila melanogaster

89 known processes

Patj (Dmel_CG12021)

CG12021 gene product from transcript CG12021-RC

(Aliases: Dmel\CG12021,dlt:discs lost,PaTJ,BcDNA:LD22238,Dpatj,Dlt,dlt,DPatj,dPATJ,PatJ,Patj/Dlt,DPATJ,dPatj,DLT,D-Patj,PATJ,CG12021)

Patj biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
asymmetric protein localization GO:0008105 33 0.789
axis specification GO:0009798 167 0.708
vesicle mediated transport GO:0016192 381 0.668
tube development GO:0035295 244 0.587
single organism cellular localization GO:1902580 180 0.544
regulation of localization GO:0032879 275 0.405
establishment of localization in cell GO:0051649 402 0.376
extracellular structure organization GO:0043062 46 0.349
epithelial cell development GO:0002064 274 0.333
cellular protein localization GO:0034613 160 0.299
tube morphogenesis GO:0035239 191 0.278
morphogenesis of embryonic epithelium GO:0016331 94 0.274
epithelial cell differentiation GO:0030855 322 0.268
protein localization GO:0008104 284 0.261
response to abiotic stimulus GO:0009628 341 0.253
Fly
cell junction organization GO:0034330 57 0.246
rna processing GO:0006396 147 0.242
establishment or maintenance of cell polarity GO:0007163 167 0.227
positive regulation of biosynthetic process GO:0009891 316 0.226
positive regulation of transport GO:0051050 92 0.211
homeostatic process GO:0042592 199 0.208
positive regulation of cellular biosynthetic process GO:0031328 316 0.197
growth GO:0040007 359 0.191
morphogenesis of an epithelium GO:0002009 276 0.188
regulation of notch signaling pathway GO:0008593 100 0.182
regulation of transport GO:0051049 181 0.160
positive regulation of nucleic acid templated transcription GO:1903508 266 0.160
cytokinesis GO:0000910 90 0.149
compound eye morphogenesis GO:0001745 249 0.148
anterior posterior axis specification GO:0009948 109 0.144
localization of cell GO:0051674 257 0.143
organonitrogen compound metabolic process GO:1901564 318 0.136
oocyte development GO:0048599 124 0.132
maternal determination of anterior posterior axis embryo GO:0008358 74 0.128
embryo development ending in birth or egg hatching GO:0009792 152 0.125
protein transport GO:0015031 155 0.125
embryonic axis specification GO:0000578 107 0.125
cellular macromolecule localization GO:0070727 220 0.117
positive regulation of rna biosynthetic process GO:1902680 266 0.116
cell division GO:0051301 248 0.115
embryonic morphogenesis GO:0048598 206 0.114
cell junction assembly GO:0034329 42 0.111
appendage morphogenesis GO:0035107 397 0.111
cellular catabolic process GO:0044248 372 0.109
establishment of protein localization GO:0045184 163 0.109
post embryonic appendage morphogenesis GO:0035120 385 0.100
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.100
muscle structure development GO:0061061 224 0.098
regionalization GO:0003002 416 0.096
larval development GO:0002164 104 0.094
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.094
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.092
oocyte construction GO:0007308 112 0.091
ras protein signal transduction GO:0007265 88 0.090
actin filament based process GO:0030029 220 0.084
oocyte axis specification GO:0007309 108 0.082
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.082
cellular protein modification process GO:0006464 438 0.082
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.081
organic substance transport GO:0071702 257 0.079
positive regulation of macromolecule metabolic process GO:0010604 405 0.079
spindle organization GO:0007051 253 0.079
macromolecular complex assembly GO:0065003 256 0.078
protein targeting GO:0006605 64 0.077
oocyte differentiation GO:0009994 145 0.074
intracellular transport GO:0046907 228 0.073
cytoskeleton dependent cytokinesis GO:0061640 81 0.071
nucleotide metabolic process GO:0009117 161 0.068
dna damage checkpoint GO:0000077 78 0.066
mitotic g2 dna damage checkpoint GO:0007095 69 0.066
digestive system development GO:0055123 149 0.065
anterior posterior axis specification embryo GO:0008595 103 0.064
regulation of cellular localization GO:0060341 136 0.064
regulation of protein transport GO:0051223 57 0.063
eye morphogenesis GO:0048592 260 0.062
nephron tubule morphogenesis GO:0072078 3 0.061
cellular macromolecular complex assembly GO:0034622 153 0.061
detection of light stimulus GO:0009583 58 0.060
Fly
cell cell junction organization GO:0045216 55 0.059
response to light stimulus GO:0009416 124 0.057
Fly
regulation of intracellular protein transport GO:0033157 46 0.056
glycosyl compound metabolic process GO:1901657 127 0.055
regulation of cell cycle GO:0051726 291 0.054
pole plasm mrna localization GO:0019094 49 0.054
blastoderm segmentation GO:0007350 159 0.054
developmental growth GO:0048589 280 0.053
regulation of catalytic activity GO:0050790 185 0.053
male gamete generation GO:0048232 201 0.052
regulation of multicellular organismal development GO:2000026 414 0.051
cell proliferation GO:0008283 299 0.050
cell migration GO:0016477 238 0.050
intracellular protein transport GO:0006886 104 0.050
regulation of cell shape GO:0008360 113 0.049
mitotic cytokinesis GO:0000281 50 0.048
ribose phosphate metabolic process GO:0019693 145 0.048
proteolysis GO:0006508 192 0.047
chromosome segregation GO:0007059 157 0.047
regulation of protein metabolic process GO:0051246 256 0.047
small gtpase mediated signal transduction GO:0007264 88 0.046
kidney development GO:0001822 3 0.045
embryonic development via the syncytial blastoderm GO:0001700 148 0.045
negative regulation of gene expression GO:0010629 387 0.044
epidermis development GO:0008544 65 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
regulation of phosphate metabolic process GO:0019220 210 0.043
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.042
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.042
nephron development GO:0072006 3 0.042
ubiquitin dependent protein catabolic process GO:0006511 78 0.041
regulation of synaptic transmission GO:0050804 69 0.041
kidney morphogenesis GO:0060993 3 0.041
cellular nitrogen compound catabolic process GO:0044270 165 0.040
axon development GO:0061564 297 0.039
extracellular matrix organization GO:0030198 32 0.039
rna localization GO:0006403 115 0.039
organic substance catabolic process GO:1901575 308 0.038
response to biotic stimulus GO:0009607 294 0.038
regulation of vesicle mediated transport GO:0060627 59 0.038
apical junction assembly GO:0043297 32 0.038
small molecule metabolic process GO:0044281 305 0.037
nephron epithelium morphogenesis GO:0072088 3 0.037
regulation of intracellular signal transduction GO:1902531 236 0.037
developmental maturation GO:0021700 172 0.036
ribonucleotide catabolic process GO:0009261 109 0.035
actin cytoskeleton organization GO:0030036 206 0.035
establishment of planar polarity GO:0001736 87 0.035
organelle localization GO:0051640 148 0.035
purine ribonucleoside catabolic process GO:0046130 112 0.035
positive regulation of intracellular protein transport GO:0090316 30 0.035
regulation of growth GO:0040008 233 0.034
negative regulation of cell differentiation GO:0045596 143 0.034
negative regulation of developmental growth GO:0048640 64 0.034
regulation of immune system process GO:0002682 176 0.034
wing disc morphogenesis GO:0007472 344 0.034
single organism membrane organization GO:0044802 93 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.033
purine nucleoside catabolic process GO:0006152 112 0.032
regulation of developmental growth GO:0048638 174 0.032
eye development GO:0001654 323 0.032
response to organic substance GO:0010033 284 0.032
anterior posterior pattern specification GO:0009952 136 0.032
membrane organization GO:0061024 112 0.032
negative regulation of cellular component organization GO:0051129 108 0.031
germarium derived egg chamber formation GO:0007293 101 0.031
regulation of molecular function GO:0065009 217 0.031
ovarian follicle cell development GO:0030707 248 0.030
hair cell differentiation GO:0035315 47 0.030
germline ring canal formation GO:0030725 13 0.030
cell cell junction assembly GO:0007043 38 0.030
plasma membrane organization GO:0007009 26 0.029
nucleoside triphosphate catabolic process GO:0009143 108 0.029
protein modification process GO:0036211 438 0.029
positive regulation of hydrolase activity GO:0051345 78 0.029
organelle fission GO:0048285 340 0.029
protein complex assembly GO:0006461 200 0.029
single organism catabolic process GO:0044712 228 0.029
regulation of protein localization GO:0032880 76 0.028
positive regulation of catalytic activity GO:0043085 118 0.028
regulation of intracellular transport GO:0032386 64 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
digestive tract morphogenesis GO:0048546 127 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.028
ribonucleotide metabolic process GO:0009259 145 0.027
mitotic g2 m transition checkpoint GO:0044818 70 0.027
positive regulation of signaling GO:0023056 243 0.027
purine nucleoside metabolic process GO:0042278 127 0.026
positive regulation of rna metabolic process GO:0051254 271 0.026
nucleoside phosphate catabolic process GO:1901292 110 0.026
nucleotide catabolic process GO:0009166 109 0.026
regulation of reproductive process GO:2000241 54 0.026
oocyte anterior posterior axis specification GO:0007314 72 0.026
gastrulation GO:0007369 70 0.026
tissue morphogenesis GO:0048729 297 0.025
columnar cuboidal epithelial cell development GO:0002066 249 0.025
establishment of spindle localization GO:0051293 22 0.025
axonogenesis GO:0007409 290 0.025
sensory perception of mechanical stimulus GO:0050954 72 0.025
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.025
organophosphate catabolic process GO:0046434 112 0.025
cytoplasmic transport GO:0016482 130 0.025
synapse organization GO:0050808 196 0.024
ncrna processing GO:0034470 30 0.024
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.023
imaginal disc derived appendage development GO:0048737 399 0.023
protein phosphorylation GO:0006468 169 0.023
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
neurological system process GO:0050877 358 0.023
Fly
regulation of immune response GO:0050776 118 0.023
endocytosis GO:0006897 310 0.023
cell maturation GO:0048469 144 0.023
response to external biotic stimulus GO:0043207 293 0.023
negative regulation of epithelial cell proliferation GO:0050680 4 0.022
embryonic pattern specification GO:0009880 174 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
tripartite regional subdivision GO:0007351 103 0.021
appendage development GO:0048736 401 0.021
organelle assembly GO:0070925 198 0.021
nucleocytoplasmic transport GO:0006913 72 0.021
apical constriction GO:0003383 18 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
morphogenesis of a polarized epithelium GO:0001738 93 0.021
positive regulation of developmental process GO:0051094 143 0.021
sex differentiation GO:0007548 81 0.021
adult behavior GO:0030534 137 0.021
forebrain development GO:0030900 2 0.021
mitotic cell cycle checkpoint GO:0007093 88 0.020
body morphogenesis GO:0010171 2 0.020
development of primary sexual characteristics GO:0045137 50 0.020
regulation of endocytosis GO:0030100 37 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
circulatory system development GO:0072359 82 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
positive regulation of transcription dna templated GO:0045893 266 0.019
mitotic nuclear division GO:0007067 213 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
ameboidal type cell migration GO:0001667 151 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
regulation of jnk cascade GO:0046328 40 0.019
negative regulation of biosynthetic process GO:0009890 277 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
ion transport GO:0006811 145 0.018
pole plasm assembly GO:0007315 61 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.018
secondary metabolic process GO:0019748 75 0.018
basement membrane organization GO:0071711 10 0.018
establishment of protein localization to membrane GO:0090150 11 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
secretion GO:0046903 109 0.018
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.018
notch signaling pathway GO:0007219 120 0.018
instar larval development GO:0002168 55 0.018
segmentation GO:0035282 207 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
nephron tubule development GO:0072080 3 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
regulation of cytoplasmic transport GO:1903649 47 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
response to lipopolysaccharide GO:0032496 4 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.017
camera type eye development GO:0043010 4 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
adherens junction organization GO:0034332 27 0.017
ion homeostasis GO:0050801 55 0.017
negative regulation of cell communication GO:0010648 223 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
purine containing compound catabolic process GO:0072523 112 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.017
adherens junction assembly GO:0034333 11 0.017
organophosphate metabolic process GO:0019637 195 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
regulation of response to stress GO:0080134 200 0.016
positive regulation of signal transduction GO:0009967 223 0.016
negative regulation of developmental process GO:0051093 201 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
neuromuscular junction development GO:0007528 149 0.016
pronuclear migration GO:0035046 4 0.016
positive regulation of molecular function GO:0044093 136 0.016
gastrulation involving germ band extension GO:0010004 36 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of neuron apoptotic process GO:0043523 16 0.015
detection of external stimulus GO:0009581 66 0.015
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
chemotaxis GO:0006935 249 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
regulation of secretion GO:0051046 44 0.015
protein complex biogenesis GO:0070271 201 0.015
nucleoside catabolic process GO:0009164 112 0.015
axon guidance GO:0007411 233 0.015
phototransduction GO:0007602 52 0.015
Fly
antimicrobial peptide production GO:0002775 46 0.015
eggshell formation GO:0030703 105 0.015
single organism biosynthetic process GO:0044711 206 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
immune system development GO:0002520 57 0.015
phagocytosis GO:0006909 215 0.015
vesicle organization GO:0016050 44 0.014
molting cycle GO:0042303 56 0.014
maintenance of protein location GO:0045185 28 0.014
aging GO:0007568 143 0.014
regulation of protein complex assembly GO:0043254 42 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.014
response to other organism GO:0051707 293 0.014
transmembrane transport GO:0055085 139 0.014
nuclear import GO:0051170 51 0.014
regulation of protein modification process GO:0031399 112 0.014
single organism intracellular transport GO:1902582 207 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.013
golgi vesicle transport GO:0048193 27 0.013
protein localization to organelle GO:0033365 82 0.013
oocyte microtubule cytoskeleton organization GO:0016325 35 0.013
regulation of neural precursor cell proliferation GO:2000177 35 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
dorsal closure GO:0007391 79 0.013
mating GO:0007618 120 0.013
sensory organ morphogenesis GO:0090596 260 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
intracellular protein transmembrane transport GO:0065002 4 0.013
regulation of cell cycle process GO:0010564 181 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
regulation of embryonic cell shape GO:0016476 30 0.013
macromolecule methylation GO:0043414 45 0.013
cellular ketone metabolic process GO:0042180 24 0.013
purine nucleotide metabolic process GO:0006163 146 0.012
response to radiation GO:0009314 155 0.012
Fly
nuclear transport GO:0051169 72 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
heterocycle catabolic process GO:0046700 166 0.012
regulation of cell proliferation GO:0042127 163 0.012
rrna processing GO:0006364 3 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
wnt signaling pathway GO:0016055 98 0.012
purine containing compound metabolic process GO:0072521 155 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
intracellular signal transduction GO:0035556 300 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
regulation of mrna processing GO:0050684 71 0.012
single organism behavior GO:0044708 391 0.012
establishment of tissue polarity GO:0007164 87 0.012
actin filament polymerization GO:0030041 27 0.012
endoderm formation GO:0001706 3 0.012
chaeta development GO:0022416 97 0.012
endomembrane system organization GO:0010256 119 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
actin filament based movement GO:0030048 26 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
macromolecule catabolic process GO:0009057 161 0.011
cellular response to carbon dioxide GO:0071244 2 0.011
male meiosis cytokinesis GO:0007112 26 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
female germline ring canal formation GO:0007301 9 0.011
apical protein localization GO:0045176 5 0.011
activation of jun kinase activity GO:0007257 3 0.011
cellular ion homeostasis GO:0006873 39 0.011
protein import into nucleus GO:0006606 51 0.011
muscle organ development GO:0007517 127 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
spindle localization GO:0051653 22 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
morphogenesis of follicular epithelium GO:0016333 36 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
immune system process GO:0002376 347 0.010
positive regulation of apoptotic cell clearance GO:2000427 2 0.010
regulation of mrna 3 end processing GO:0031440 7 0.010
cytoplasm organization GO:0007028 64 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
gland development GO:0048732 191 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
actin polymerization or depolymerization GO:0008154 31 0.010
nuclear division GO:0000280 332 0.010
cellular protein complex assembly GO:0043623 71 0.010
catabolic process GO:0009056 409 0.010

Patj disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.171
nervous system disease DOID:863 0 0.019
disease of cellular proliferation DOID:14566 0 0.014