Drosophila melanogaster

4 known processes

PH4alphaNE2 (Dmel_CG9720)

prolyl-4-hydroxylase-alpha NE2

(Aliases: Dmel\CG9720,CG9720)

PH4alphaNE2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein hydroxylation GO:0018126 1 0.388
Rat
cholesterol homeostasis GO:0042632 3 0.231
small molecule metabolic process GO:0044281 305 0.105
lateral inhibition GO:0046331 206 0.096
Fly
peptidyl proline modification GO:0018208 3 0.087
Rat
sterol homeostasis GO:0055092 4 0.079
cytokinesis GO:0000910 90 0.079
negative regulation of cellular metabolic process GO:0031324 382 0.052
multi organism behavior GO:0051705 175 0.052
cell division GO:0051301 248 0.052
protein modification process GO:0036211 438 0.049
Rat
mating GO:0007618 120 0.048
mating behavior GO:0007617 106 0.048
negative regulation of gene expression GO:0010629 387 0.047
peptidyl amino acid modification GO:0018193 105 0.047
Rat
reproductive behavior GO:0019098 122 0.047
insemination GO:0007320 22 0.046
oxoacid metabolic process GO:0043436 103 0.046
response to organic substance GO:0010033 284 0.045
carboxylic acid metabolic process GO:0019752 92 0.045
cellular protein modification process GO:0006464 438 0.044
Rat
chemotaxis GO:0006935 249 0.043
fatty acid metabolic process GO:0006631 20 0.042
exocrine system development GO:0035272 162 0.040
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.040
organonitrogen compound metabolic process GO:1901564 318 0.039
macromolecular complex assembly GO:0065003 256 0.038
multi organism reproductive behavior GO:0044705 121 0.037
endocytosis GO:0006897 310 0.035
triglyceride homeostasis GO:0070328 18 0.035
organic acid metabolic process GO:0006082 103 0.035
lipid metabolic process GO:0006629 121 0.035
response to ethanol GO:0045471 59 0.034
organic substance catabolic process GO:1901575 308 0.034
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
regulation of organelle organization GO:0033043 196 0.032
lipid homeostasis GO:0055088 33 0.032
cell cell signaling involved in cell fate commitment GO:0045168 210 0.031
Fly
taxis GO:0042330 304 0.031
localization of cell GO:0051674 257 0.030
response to abiotic stimulus GO:0009628 341 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.030
catabolic process GO:0009056 409 0.029
axonogenesis GO:0007409 290 0.029
positive regulation of response to stimulus GO:0048584 323 0.028
response to nitrogen compound GO:1901698 90 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
positive regulation of signal transduction GO:0009967 223 0.027
response to alcohol GO:0097305 95 0.027
organic hydroxy compound metabolic process GO:1901615 83 0.027
response to oxygen containing compound GO:1901700 200 0.027
neuron projection guidance GO:0097485 241 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
negative regulation of cell communication GO:0010648 223 0.025
cellular amino acid metabolic process GO:0006520 61 0.025
glycerolipid catabolic process GO:0046503 3 0.025
homeostatic process GO:0042592 199 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
negative regulation of signaling GO:0023057 219 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
cellular lipid metabolic process GO:0044255 83 0.025
negative regulation of signal transduction GO:0009968 206 0.024
sperm competition GO:0046692 21 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
multi multicellular organism process GO:0044706 123 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
positive regulation of gene expression GO:0010628 290 0.023
chemical homeostasis GO:0048878 92 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.023
multicellular organismal reproductive behavior GO:0033057 110 0.023
cell proliferation GO:0008283 299 0.023
regulation of cell cycle GO:0051726 291 0.023
negative regulation of developmental process GO:0051093 201 0.022
regulation of multi organism process GO:0043900 131 0.022
chromosome organization GO:0051276 360 0.022
single organism catabolic process GO:0044712 228 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
phagocytosis GO:0006909 215 0.022
camera type eye development GO:0043010 4 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
axon guidance GO:0007411 233 0.021
positive regulation of cell communication GO:0010647 250 0.021
monocarboxylic acid metabolic process GO:0032787 29 0.021
positive regulation of signaling GO:0023056 243 0.021
proteolysis GO:0006508 192 0.021
response to nutrient levels GO:0031667 114 0.021
regulation of response to external stimulus GO:0032101 115 0.021
cytoskeleton dependent cytokinesis GO:0061640 81 0.021
neurological system process GO:0050877 358 0.021
ameboidal type cell migration GO:0001667 151 0.021
response to lipopolysaccharide GO:0032496 4 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
eye development GO:0001654 323 0.020
male courtship behavior GO:0008049 63 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
regulation of nervous system development GO:0051960 248 0.020
epithelial cell development GO:0002064 274 0.020
sensory organ morphogenesis GO:0090596 260 0.020
axon development GO:0061564 297 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
courtship behavior GO:0007619 68 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
cellular amine metabolic process GO:0044106 12 0.019
stem cell proliferation GO:0072089 88 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
organelle assembly GO:0070925 198 0.019
response to other organism GO:0051707 293 0.019
response to endogenous stimulus GO:0009719 119 0.019
regulation of response to stress GO:0080134 200 0.019
response to biotic stimulus GO:0009607 294 0.018
regulation of cell cycle process GO:0010564 181 0.018
salivary gland morphogenesis GO:0007435 145 0.018
Fly
forebrain development GO:0030900 2 0.018
gland morphogenesis GO:0022612 145 0.018
Fly
notch signaling pathway GO:0007219 120 0.018
amine metabolic process GO:0009308 12 0.018
single organism behavior GO:0044708 391 0.018
stem cell differentiation GO:0048863 117 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
central nervous system development GO:0007417 201 0.017
regionalization GO:0003002 416 0.017
response to organonitrogen compound GO:0010243 75 0.017
regulation of cell development GO:0060284 215 0.017
regulation of immune response GO:0050776 118 0.017
programmed cell death GO:0012501 257 0.017
cell death GO:0008219 279 0.017
cellular catabolic process GO:0044248 372 0.017
mitotic nuclear division GO:0007067 213 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
anion homeostasis GO:0055081 3 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
purine containing compound metabolic process GO:0072521 155 0.016
cell motility GO:0048870 251 0.016
response to radiation GO:0009314 155 0.016
negative regulation of transcription dna templated GO:0045892 237 0.016
response to wounding GO:0009611 94 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
regulation of cell death GO:0010941 173 0.016
response to light stimulus GO:0009416 124 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
developmental maturation GO:0021700 172 0.015
regulation of cell differentiation GO:0045595 302 0.015
gland development GO:0048732 191 0.015
Fly
segmentation GO:0035282 207 0.015
nuclear division GO:0000280 332 0.015
developmental growth GO:0048589 280 0.015
organic substance transport GO:0071702 257 0.015
response to bacterium GO:0009617 198 0.015
body morphogenesis GO:0010171 2 0.015
death GO:0016265 284 0.015
regulation of response to biotic stimulus GO:0002831 63 0.015
nucleoside metabolic process GO:0009116 127 0.015
oxidation reduction process GO:0055114 123 0.015
Rat
glycosyl compound metabolic process GO:1901657 127 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
organelle fission GO:0048285 340 0.014
epithelial cell differentiation GO:0030855 322 0.014
embryonic pattern specification GO:0009880 174 0.014
compound eye development GO:0048749 307 0.014
female mating behavior GO:0060180 30 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
appendage development GO:0048736 401 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
response to external biotic stimulus GO:0043207 293 0.014
steroid metabolic process GO:0008202 20 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
telencephalon development GO:0021537 2 0.014
eye morphogenesis GO:0048592 260 0.014
male mating behavior GO:0060179 70 0.014
regulation of mapk cascade GO:0043408 92 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
response to organic cyclic compound GO:0014070 89 0.014
tissue morphogenesis GO:0048729 297 0.014
regulation of female receptivity post mating GO:0046008 17 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
regulation of female receptivity GO:0045924 24 0.013
regulation of catalytic activity GO:0050790 185 0.013
phosphorylation GO:0016310 294 0.013
vesicle mediated transport GO:0016192 381 0.013
male gamete generation GO:0048232 201 0.013
aromatic compound catabolic process GO:0019439 166 0.013
regulation of protein metabolic process GO:0051246 256 0.013
salivary gland development GO:0007431 162 0.013
Fly
asymmetric stem cell division GO:0098722 49 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
single organism biosynthetic process GO:0044711 206 0.013
protein complex biogenesis GO:0070271 201 0.013
protein complex assembly GO:0006461 200 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
muscle organ development GO:0007517 127 0.013
embryonic morphogenesis GO:0048598 206 0.013
negative regulation of programmed cell death GO:0043069 72 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
cognition GO:0050890 141 0.012
pigmentation GO:0043473 75 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
regulation of catabolic process GO:0009894 170 0.012
response to oxygen levels GO:0070482 59 0.012
long term memory GO:0007616 62 0.012
regulation of immune system process GO:0002682 176 0.012
cell migration GO:0016477 238 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
heterocycle catabolic process GO:0046700 166 0.012
photoreceptor cell development GO:0042461 96 0.012
wound healing GO:0042060 75 0.012
apoptotic process GO:0006915 159 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
spermatid differentiation GO:0048515 114 0.012
appendage morphogenesis GO:0035107 397 0.012
response to organophosphorus GO:0046683 2 0.012
cellular ketone metabolic process GO:0042180 24 0.012
response to decreased oxygen levels GO:0036293 58 0.012
wnt signaling pathway GO:0016055 98 0.012
lipid biosynthetic process GO:0008610 46 0.012
intracellular signal transduction GO:0035556 300 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
regulation of programmed cell death GO:0043067 152 0.012
response to extracellular stimulus GO:0009991 116 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
anterior posterior pattern specification GO:0009952 136 0.012
digestive system development GO:0055123 149 0.012
open tracheal system development GO:0007424 204 0.012
neural precursor cell proliferation GO:0061351 75 0.011
rna processing GO:0006396 147 0.011
head development GO:0060322 135 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
nucleoside catabolic process GO:0009164 112 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
cellular hormone metabolic process GO:0034754 23 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
tube morphogenesis GO:0035239 191 0.011
dendrite morphogenesis GO:0048813 199 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
heart process GO:0003015 37 0.011
mushroom body development GO:0016319 70 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
brain development GO:0007420 120 0.011
regulation of localization GO:0032879 275 0.011
chromatin modification GO:0016568 147 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
growth GO:0040007 359 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
stem cell development GO:0048864 79 0.011
mitotic cytokinesis GO:0000281 50 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
regulation of molecular function GO:0065009 217 0.011
retina development in camera type eye GO:0060041 4 0.011
organophosphate catabolic process GO:0046434 112 0.011
macromolecule catabolic process GO:0009057 161 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
tripartite regional subdivision GO:0007351 103 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
maintenance of location GO:0051235 73 0.010
cell maturation GO:0048469 144 0.010
nucleotide metabolic process GO:0009117 161 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
negative regulation of homeostatic process GO:0032845 2 0.010
detection of external stimulus GO:0009581 66 0.010
regulation of neurogenesis GO:0050767 158 0.010
purine containing compound catabolic process GO:0072523 112 0.010
peptidyl proline hydroxylation GO:0019511 1 0.010
Rat
spindle organization GO:0007051 253 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
oocyte construction GO:0007308 112 0.010

PH4alphaNE2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of metabolism DOID:0014667 0 0.011