Drosophila melanogaster

170 known processes

tsr (Dmel_CG4254)

twinstar

(Aliases: Adf,T8,l(2)k03101,Tsr,cofilin/actin depolymerizing factor homolog,D-cof,l(2)k05633,ADF,l(2)03101,CG4254,Cadf,cofilin/ADF,12/8,cofilin,ADF/cofilin,D61,l(2)k13409,Dmel\CG4254,ntf)

tsr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cytokinesis GO:0033206 33 0.990
ovarian follicle cell migration GO:0007297 121 0.986
regulation of cell differentiation GO:0045595 302 0.984
actin filament based process GO:0030029 220 0.983
regulation of neurogenesis GO:0050767 158 0.978
regulation of cell development GO:0060284 215 0.966
regulation of multicellular organismal development GO:2000026 414 0.964
regulation of nervous system development GO:0051960 248 0.964
gland development GO:0048732 191 0.954
positive regulation of multicellular organismal process GO:0051240 143 0.953
male gamete generation GO:0048232 201 0.949
cell migration GO:0016477 238 0.943
spermatid development GO:0007286 98 0.925
regulation of cellular component biogenesis GO:0044087 201 0.921
negative regulation of gene expression GO:0010629 387 0.906
axon development GO:0061564 297 0.894
macromolecular complex assembly GO:0065003 256 0.885
regulation of cell projection organization GO:0031344 92 0.871
protein complex assembly GO:0006461 200 0.871
cell death GO:0008219 279 0.865
dendrite development GO:0016358 204 0.850
compound eye photoreceptor cell differentiation GO:0001751 140 0.848
muscle cell differentiation GO:0042692 103 0.843
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.830
Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.821
regulation of anatomical structure morphogenesis GO:0022603 242 0.783
regulation of neuron differentiation GO:0045664 103 0.748
ovarian follicle cell development GO:0030707 248 0.747
regulation of programmed cell death GO:0043067 152 0.747
actomyosin structure organization GO:0031032 56 0.743
Worm
cytoskeleton dependent cytokinesis GO:0061640 81 0.739
actin cytoskeleton organization GO:0030036 206 0.734
epithelial cell differentiation GO:0030855 322 0.731
apoptotic process GO:0006915 159 0.710
regulation of response to stress GO:0080134 200 0.710
macromolecule catabolic process GO:0009057 161 0.688
Worm
spermatogenesis GO:0007283 200 0.685
catabolic process GO:0009056 409 0.667
Worm
protein complex biogenesis GO:0070271 201 0.665
regulation of apoptotic process GO:0042981 130 0.648
regulation of protein metabolic process GO:0051246 256 0.637
protein modification by small protein conjugation or removal GO:0070647 106 0.627
purine ribonucleotide catabolic process GO:0009154 109 0.624
positive regulation of developmental process GO:0051094 143 0.620
head development GO:0060322 135 0.587
programmed cell death GO:0012501 257 0.568
negative regulation of multicellular organismal process GO:0051241 142 0.560
cytokinesis GO:0000910 90 0.544
determination of adult lifespan GO:0008340 137 0.537
Worm
spermatid differentiation GO:0048515 114 0.524
organonitrogen compound metabolic process GO:1901564 318 0.519
purine nucleoside triphosphate catabolic process GO:0009146 108 0.510
organonitrogen compound catabolic process GO:1901565 128 0.505
regulation of cell morphogenesis GO:0022604 163 0.501
purine containing compound catabolic process GO:0072523 112 0.498
cellular catabolic process GO:0044248 372 0.495
cuticle development GO:0042335 86 0.478
organic substance catabolic process GO:1901575 308 0.458
Worm
eye photoreceptor cell development GO:0042462 81 0.453
positive regulation of programmed cell death GO:0043068 62 0.452
organophosphate catabolic process GO:0046434 112 0.450
border follicle cell migration GO:0007298 113 0.449
establishment of planar polarity GO:0001736 87 0.449
positive regulation of molecular function GO:0044093 136 0.427
ribonucleoside triphosphate catabolic process GO:0009203 108 0.423
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.413
compound eye photoreceptor development GO:0042051 78 0.405
brain development GO:0007420 120 0.404
nucleoside phosphate metabolic process GO:0006753 162 0.398
male meiosis cytokinesis GO:0007112 26 0.396
purine nucleotide catabolic process GO:0006195 109 0.383
axonogenesis GO:0007409 290 0.383
central nervous system development GO:0007417 201 0.379
dendrite morphogenesis GO:0048813 199 0.378
proteolysis GO:0006508 192 0.371
nucleoside catabolic process GO:0009164 112 0.356
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.353
striated muscle cell differentiation GO:0051146 90 0.346
Worm
nucleoside triphosphate catabolic process GO:0009143 108 0.342
regulation of proteolysis GO:0030162 87 0.342
regulation of cell death GO:0010941 173 0.337
negative regulation of rna metabolic process GO:0051253 251 0.335
protein modification process GO:0036211 438 0.333
death GO:0016265 284 0.325
regulation of cytoskeleton organization GO:0051493 89 0.318
Worm
ras protein signal transduction GO:0007265 88 0.318
negative regulation of transcription dna templated GO:0045892 237 0.298
ribonucleotide catabolic process GO:0009261 109 0.295
immune system process GO:0002376 347 0.294
regulation of response to external stimulus GO:0032101 115 0.289
negative regulation of developmental process GO:0051093 201 0.285
cell division GO:0051301 248 0.278
compound eye development GO:0048749 307 0.275
regulation of neuron projection development GO:0010975 69 0.269
purine ribonucleoside metabolic process GO:0046128 127 0.267
morphogenesis of an epithelium GO:0002009 276 0.265
positive regulation of nervous system development GO:0051962 69 0.264
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.263
cellular macromolecular complex assembly GO:0034622 153 0.261
negative regulation of cellular component organization GO:0051129 108 0.251
nucleoside triphosphate metabolic process GO:0009141 120 0.247
cellular nitrogen compound catabolic process GO:0044270 165 0.245
regulation of catalytic activity GO:0050790 185 0.240
negative regulation of cellular metabolic process GO:0031324 382 0.239
positive regulation of nucleic acid templated transcription GO:1903508 266 0.239
glycosyl compound catabolic process GO:1901658 112 0.235
columnar cuboidal epithelial cell development GO:0002066 249 0.225
muscle structure development GO:0061061 224 0.214
Worm
cell maturation GO:0048469 144 0.212
eye photoreceptor cell differentiation GO:0001754 145 0.209
ribose phosphate metabolic process GO:0019693 145 0.208
immune system development GO:0002520 57 0.208
endocytosis GO:0006897 310 0.203
growth GO:0040007 359 0.202
Worm
compound eye morphogenesis GO:0001745 249 0.201
hemopoiesis GO:0030097 46 0.199
single organism intracellular transport GO:1902582 207 0.198
regulation of molecular function GO:0065009 217 0.193
purine nucleoside triphosphate metabolic process GO:0009144 119 0.192
positive regulation of macromolecule metabolic process GO:0010604 405 0.192
cellular protein modification process GO:0006464 438 0.192
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.191
neuron projection guidance GO:0097485 241 0.190
negative regulation of response to stimulus GO:0048585 258 0.189
regulation of behavior GO:0050795 75 0.189
purine ribonucleoside catabolic process GO:0046130 112 0.189
organophosphate metabolic process GO:0019637 195 0.187
spermatocyte division GO:0048137 13 0.184
regulation of cell cycle process GO:0010564 181 0.182
nuclear migration GO:0007097 20 0.181
positive regulation of rna biosynthetic process GO:1902680 266 0.180
protein ubiquitination GO:0016567 70 0.178
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.178
hemocyte differentiation GO:0042386 38 0.173
muscle cell development GO:0055001 50 0.172
Worm
regulation of catabolic process GO:0009894 170 0.172
small molecule metabolic process GO:0044281 305 0.170
regulation of gene expression epigenetic GO:0040029 128 0.169
intracellular signal transduction GO:0035556 300 0.168
gonad development GO:0008406 50 0.167
regulation of actin filament based process GO:0032970 42 0.166
Worm
cell proliferation GO:0008283 299 0.164
regulation of intracellular signal transduction GO:1902531 236 0.162
nucleotide metabolic process GO:0009117 161 0.161
regulation of wnt signaling pathway GO:0030111 68 0.160
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.160
positive regulation of cell development GO:0010720 61 0.160
instar larval development GO:0002168 55 0.159
gliogenesis GO:0042063 80 0.158
positive regulation of cell death GO:0010942 69 0.158
negative regulation of cell communication GO:0010648 223 0.154
nucleus localization GO:0051647 34 0.153
positive regulation of nucleoside metabolic process GO:0045979 47 0.152
ribonucleotide metabolic process GO:0009259 145 0.149
purine nucleotide metabolic process GO:0006163 146 0.146
chemotaxis GO:0006935 249 0.146
regulation of mitotic cell cycle phase transition GO:1901990 130 0.146
localization of cell GO:0051674 257 0.144
regulation of organelle organization GO:0033043 196 0.143
Worm
larval development GO:0002164 104 0.142
Worm
ribonucleoside metabolic process GO:0009119 127 0.142
purine containing compound metabolic process GO:0072521 155 0.137
carbohydrate derivative catabolic process GO:1901136 118 0.136
tissue migration GO:0090130 155 0.135
receptor mediated endocytosis GO:0006898 21 0.133
purine nucleoside metabolic process GO:0042278 127 0.133
positive regulation of neurogenesis GO:0050769 41 0.132
transcription from rna polymerase ii promoter GO:0006366 368 0.132
positive regulation of gene expression GO:0010628 290 0.131
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.130
developmental growth GO:0048589 280 0.129
nucleobase containing compound catabolic process GO:0034655 165 0.126
response to wounding GO:0009611 94 0.125
cellular macromolecule localization GO:0070727 220 0.124
protein transport GO:0015031 155 0.123
negative regulation of catabolic process GO:0009895 36 0.122
circadian rhythm GO:0007623 105 0.121
appendage morphogenesis GO:0035107 397 0.120
protein maturation GO:0051604 71 0.119
protein modification by small protein conjugation GO:0032446 79 0.119
eye development GO:0001654 323 0.119
cell growth GO:0016049 108 0.118
histone modification GO:0016570 106 0.117
modification dependent macromolecule catabolic process GO:0043632 79 0.117
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.116
positive regulation of rna metabolic process GO:0051254 271 0.116
actin filament organization GO:0007015 126 0.113
positive regulation of response to stimulus GO:0048584 323 0.112
regulation of axonogenesis GO:0050770 32 0.107
germ line cyst formation GO:0048134 44 0.107
ribonucleoside triphosphate metabolic process GO:0009199 119 0.105
cell motility GO:0048870 251 0.105
tissue morphogenesis GO:0048729 297 0.104
regulation of organ morphogenesis GO:2000027 78 0.103
regulation of cellular protein metabolic process GO:0032268 243 0.103
mitotic cell cycle phase transition GO:0044772 138 0.101
nucleoside phosphate catabolic process GO:1901292 110 0.100
negative regulation of cell cycle GO:0045786 116 0.099
regulation of response to wounding GO:1903034 19 0.094
meiotic nuclear division GO:0007126 151 0.094
carbohydrate derivative metabolic process GO:1901135 217 0.093
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.093
microtubule organizing center organization GO:0031023 168 0.088
cell cycle phase transition GO:0044770 140 0.088
negative regulation of gene expression epigenetic GO:0045814 77 0.088
negative regulation of signal transduction GO:0009968 206 0.087
regulation of cell projection assembly GO:0060491 30 0.086
regulation of cell cycle phase transition GO:1901987 130 0.085
regulation of cellular component size GO:0032535 98 0.084
Worm
salivary gland morphogenesis GO:0007435 145 0.084
positive regulation of cell differentiation GO:0045597 64 0.083
eye morphogenesis GO:0048592 260 0.083
positive regulation of signaling GO:0023056 243 0.082
multicellular organismal reproductive behavior GO:0033057 110 0.082
regulation of protein modification process GO:0031399 112 0.081
protein localization GO:0008104 284 0.081
guanosine containing compound metabolic process GO:1901068 74 0.080
salivary gland development GO:0007431 162 0.079
regulation of developmental growth GO:0048638 174 0.079
negative regulation of cellular catabolic process GO:0031330 34 0.078
rna interference GO:0016246 27 0.077
regulation of protein catabolic process GO:0042176 55 0.076
sensory organ morphogenesis GO:0090596 260 0.075
negative regulation of cell differentiation GO:0045596 143 0.074
regulation of actin polymerization or depolymerization GO:0008064 27 0.074
Worm
glycosyl compound metabolic process GO:1901657 127 0.073
reproductive structure development GO:0048608 74 0.073
establishment or maintenance of cell polarity GO:0007163 167 0.072
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.070
reproductive system development GO:0061458 74 0.070
regulation of defense response to virus by host GO:0050691 10 0.070
guanosine containing compound catabolic process GO:1901069 74 0.068
tube development GO:0035295 244 0.068
protein targeting GO:0006605 64 0.066
negative regulation of nervous system development GO:0051961 92 0.066
pronuclear migration GO:0035046 4 0.065
nucleoside metabolic process GO:0009116 127 0.064
cell projection assembly GO:0030031 94 0.064
establishment of organelle localization GO:0051656 122 0.064
developmental programmed cell death GO:0010623 138 0.063
organic cyclic compound catabolic process GO:1901361 168 0.063
neuromuscular junction development GO:0007528 149 0.063
ubiquitin dependent protein catabolic process GO:0006511 78 0.063
regulation of locomotion GO:0040012 42 0.063
ameboidal type cell migration GO:0001667 151 0.063
establishment of nucleus localization GO:0040023 26 0.061
protein catabolic process GO:0030163 101 0.061
Worm
circulatory system development GO:0072359 82 0.060
protein import GO:0017038 55 0.059
cell cycle checkpoint GO:0000075 95 0.058
cellularization GO:0007349 90 0.058
regulation of actin filament polymerization GO:0030833 25 0.058
Worm
meiotic cell cycle process GO:1903046 132 0.058
regulation of actin cytoskeleton organization GO:0032956 42 0.057
Worm
response to virus GO:0009615 28 0.057
regulation of actin filament length GO:0030832 27 0.056
Worm
regulation of hydrolase activity GO:0051336 97 0.056
ribonucleoprotein complex subunit organization GO:0071826 28 0.056
positive regulation of cell projection organization GO:0031346 29 0.056
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
positive regulation of signal transduction GO:0009967 223 0.055
covalent chromatin modification GO:0016569 106 0.055
regulation of cell proliferation GO:0042127 163 0.054
single organism behavior GO:0044708 391 0.054
positive regulation of apoptotic signaling pathway GO:2001235 4 0.054
humoral immune response GO:0006959 117 0.053
negative regulation of organelle organization GO:0010639 56 0.053
regulation of endopeptidase activity GO:0052548 36 0.051
regulation of proteasomal protein catabolic process GO:0061136 39 0.050
germarium derived female germ line cyst formation GO:0030727 42 0.050
organelle fission GO:0048285 340 0.050
negative regulation of wnt signaling pathway GO:0030178 28 0.049
epidermis development GO:0008544 65 0.049
taxis GO:0042330 304 0.049
histone acetylation GO:0016573 38 0.049
regulation of growth GO:0040008 233 0.049
regulation of cellular response to stress GO:0080135 89 0.049
regulation of chromosome organization GO:0033044 64 0.048
positive regulation of neuron differentiation GO:0045666 26 0.048
negative regulation of neurotransmitter secretion GO:0046929 2 0.048
negative regulation of apoptotic process GO:0043066 63 0.047
regulation of establishment of protein localization GO:0070201 61 0.047
nuclear import GO:0051170 51 0.047
negative regulation of programmed cell death GO:0043069 72 0.047
centrosome organization GO:0051297 163 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.045
negative regulation of signaling GO:0023057 219 0.045
regulation of nucleotide catabolic process GO:0030811 48 0.045
heterocycle catabolic process GO:0046700 166 0.045
negative regulation of cell development GO:0010721 62 0.044
mitotic dna damage checkpoint GO:0044773 74 0.044
epithelial cell development GO:0002064 274 0.044
regulation of phosphorylation GO:0042325 147 0.044
genitalia development GO:0048806 26 0.044
Worm
purine nucleoside catabolic process GO:0006152 112 0.044
regulation of gtpase activity GO:0043087 44 0.043
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.043
female germ line cyst formation GO:0048135 42 0.042
positive regulation of phosphorus metabolic process GO:0010562 139 0.042
neuron remodeling GO:0016322 29 0.042
positive regulation of catabolic process GO:0009896 105 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
histone h4 acetylation GO:0043967 13 0.041
cellular macromolecule catabolic process GO:0044265 136 0.041
modification dependent protein catabolic process GO:0019941 78 0.041
actin filament depolymerization GO:0030042 5 0.041
Worm
regionalization GO:0003002 416 0.041
lateral inhibition GO:0046331 206 0.041
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.040
regulation of dendrite development GO:0050773 37 0.040
protein targeting to nucleus GO:0044744 51 0.040
nucleobase containing small molecule metabolic process GO:0055086 174 0.040
positive regulation of nucleotide metabolic process GO:0045981 55 0.040
single organism catabolic process GO:0044712 228 0.039
cellular protein localization GO:0034613 160 0.039
epithelium migration GO:0090132 148 0.039
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
body morphogenesis GO:0010171 2 0.039
non sensory hair organization GO:0035316 47 0.038
negative regulation of cell cycle process GO:0010948 109 0.038
skin development GO:0043588 65 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
histone deubiquitination GO:0016578 8 0.036
ribonucleoside catabolic process GO:0042454 112 0.036
positive regulation of proteolysis GO:0045862 52 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.036
eggshell formation GO:0030703 105 0.036
gland morphogenesis GO:0022612 145 0.036
protein processing GO:0016485 68 0.036
negative regulation of mitotic cell cycle GO:0045930 109 0.035
positive regulation of cellular component biogenesis GO:0044089 80 0.035
Worm
peptidyl lysine modification GO:0018205 57 0.035
negative regulation of cell death GO:0060548 81 0.035
protein import into nucleus GO:0006606 51 0.034
development of primary sexual characteristics GO:0045137 50 0.034
regulation of cell cycle GO:0051726 291 0.034
defense response GO:0006952 300 0.034
regulation of cellular protein catabolic process GO:1903362 44 0.034
wing disc morphogenesis GO:0007472 344 0.033
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.033
establishment of localization in cell GO:0051649 402 0.033
positive regulation of hydrolase activity GO:0051345 78 0.033
cognition GO:0050890 141 0.033
positive regulation of cellular catabolic process GO:0031331 95 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.032
neurological system process GO:0050877 358 0.032
epidermal cell differentiation GO:0009913 51 0.031
gene silencing GO:0016458 138 0.031
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
establishment of spindle orientation GO:0051294 18 0.030
meiotic cell cycle GO:0051321 171 0.030
mitotic cytokinesis GO:0000281 50 0.030
positive regulation of cytoskeleton organization GO:0051495 21 0.030
Worm
positive regulation of intracellular signal transduction GO:1902533 116 0.030
positive regulation of multi organism process GO:0043902 40 0.030
regulation of peptidase activity GO:0052547 39 0.029
ncrna metabolic process GO:0034660 43 0.029
oviposition GO:0018991 19 0.029
proteasomal protein catabolic process GO:0010498 59 0.029
regulation of canonical wnt signaling pathway GO:0060828 15 0.029
regulation of localization GO:0032879 275 0.028
positive regulation of protein metabolic process GO:0051247 128 0.028
multi organism behavior GO:0051705 175 0.028
regulation of gtp catabolic process GO:0033124 44 0.028
positive regulation of defense response to virus by host GO:0002230 10 0.028
positive regulation of ribosome biogenesis GO:0090070 3 0.027
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.027
positive regulation of cell cycle GO:0045787 43 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.026
protein localization to plasma membrane GO:0072659 13 0.026
antimicrobial humoral response GO:0019730 99 0.026
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
negative regulation of protein processing GO:0010955 31 0.026
regulation of r7 cell differentiation GO:0045676 15 0.026
cellular protein catabolic process GO:0044257 83 0.026
regulation of purine nucleotide metabolic process GO:1900542 62 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
vesicle mediated transport GO:0016192 381 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
membrane organization GO:0061024 112 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
exocrine system development GO:0035272 162 0.024
regulation of anatomical structure size GO:0090066 163 0.024
Worm
rna processing GO:0006396 147 0.024
nucleotide catabolic process GO:0009166 109 0.024
negative regulation of catalytic activity GO:0043086 42 0.024
small gtpase mediated signal transduction GO:0007264 88 0.023
morphogenesis of a branching structure GO:0001763 45 0.023
regulation of cellular component movement GO:0051270 42 0.023
neuron maturation GO:0042551 31 0.023
regulation of dendrite morphogenesis GO:0048814 28 0.022
oocyte construction GO:0007308 112 0.022
regulation of cysteine type endopeptidase activity GO:2000116 27 0.022
lipid storage GO:0019915 38 0.022
sex differentiation GO:0007548 81 0.022
axon guidance GO:0007411 233 0.022
striated muscle myosin thick filament assembly GO:0071688 3 0.022
organic substance transport GO:0071702 257 0.021
rna splicing GO:0008380 83 0.021
chromatin organization GO:0006325 207 0.021
appendage development GO:0048736 401 0.021
posttranscriptional gene silencing GO:0016441 46 0.021
dephosphorylation GO:0016311 51 0.021
response to oxygen containing compound GO:1901700 200 0.021
imaginal disc derived wing hair organization GO:0035317 45 0.021
regulation of sister chromatid cohesion GO:0007063 2 0.020
positive regulation of peptidase activity GO:0010952 29 0.020
positive regulation of protein import into nucleus translocation GO:0033160 2 0.020
regulation of cell migration GO:0030334 22 0.019
glial cell migration GO:0008347 31 0.019
secretion GO:0046903 109 0.019
positive regulation of cell communication GO:0010647 250 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
response to starvation GO:0042594 97 0.018
positive regulation of apoptotic process GO:0043065 47 0.018
response to extracellular stimulus GO:0009991 116 0.018
response to nutrient levels GO:0031667 114 0.018
autophagy GO:0006914 108 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
regulation of jnk cascade GO:0046328 40 0.018
regulation of protein processing GO:0070613 32 0.018
regulation of protein localization GO:0032880 76 0.017
regulation of cellular localization GO:0060341 136 0.017
regulation of immune system process GO:0002682 176 0.017
synaptic growth at neuromuscular junction GO:0051124 119 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
positive regulation of organelle organization GO:0010638 65 0.017
Worm
protein phosphorylation GO:0006468 169 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
positive regulation of response to external stimulus GO:0032103 44 0.017
wnt signaling pathway GO:0016055 98 0.017
regulation of protein maturation GO:1903317 32 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.017
regulation of mapk cascade GO:0043408 92 0.017
organic acid metabolic process GO:0006082 103 0.017
gene silencing by rna GO:0031047 57 0.017
epithelial cell migration GO:0010631 148 0.016
positive regulation of cell cycle process GO:0090068 28 0.016
secretion by cell GO:0032940 101 0.016
cellular component disassembly GO:0022411 46 0.016
Worm
morphogenesis of a branching epithelium GO:0061138 45 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
single organism nuclear import GO:1902593 51 0.016
phagocytosis GO:0006909 215 0.016
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.015
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.015
negative regulation of phosphatase activity GO:0010923 3 0.015
stem cell proliferation GO:0072089 88 0.015
protein polymerization GO:0051258 42 0.015
cellular protein complex assembly GO:0043623 71 0.015
cellular response to sterol depletion GO:0071501 3 0.015
establishment of monopolar cell polarity GO:0061162 15 0.015
phosphorylation GO:0016310 294 0.015
peptide metabolic process GO:0006518 80 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.014
intracellular transport GO:0046907 228 0.014
cell cycle arrest GO:0007050 4 0.014
dorsal appendage formation GO:0046843 47 0.014
mitotic spindle organization GO:0007052 220 0.014
tube morphogenesis GO:0035239 191 0.014
locomotory behavior GO:0007626 176 0.013
aromatic compound catabolic process GO:0019439 166 0.013
regulation of epithelial cell differentiation GO:0030856 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
stem cell differentiation GO:0048863 117 0.013
developmental cell growth GO:0048588 52 0.013
myofibril assembly GO:0030239 36 0.013
Worm
eggshell chorion assembly GO:0007306 66 0.013
tube formation GO:0035148 21 0.013
organelle assembly GO:0070925 198 0.013
Worm
regulation of hemocyte proliferation GO:0035206 37 0.013
regulation of nuclear division GO:0051783 58 0.013

tsr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
familial meningioma DOID:4586 0 0.028
nervous system cancer DOID:3093 0 0.028
central nervous system cancer DOID:3620 0 0.028
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
organ system cancer DOID:0050686 0 0.028
meningioma DOID:3565 0 0.028
nervous system disease DOID:863 0 0.024
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
heart disease DOID:114 0 0.017
cardiomyopathy DOID:0050700 0 0.017
cardiovascular system disease DOID:1287 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017
dilated cardiomyopathy DOID:12930 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
female reproductive system disease DOID:229 0 0.013
ovarian disease DOID:1100 0 0.013
reproductive system disease DOID:15 0 0.013