Drosophila melanogaster

65 known processes

Drl-2 (Dmel_CG3915)

Derailed 2

(Aliases: CG3915,dnl,CG12463,Dmel\CG3915,drl-2,DNT-like)

Drl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon development GO:0061564 297 0.771
axonogenesis GO:0007409 290 0.682
regulation of growth GO:0040008 233 0.522
Mouse
developmental growth GO:0048589 280 0.442
Zebrafish Mouse
neurological system process GO:0050877 358 0.427
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.424
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.356
Zebrafish Mouse
head development GO:0060322 135 0.334
Mouse
taxis GO:0042330 304 0.328
axon extension GO:0048675 32 0.303
Mouse
negative regulation of developmental process GO:0051093 201 0.300
Mouse
regulation of cell size GO:0008361 63 0.299
Mouse
regulation of cell morphogenesis GO:0022604 163 0.281
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.276
neuron projection extension GO:1990138 32 0.256
Mouse
sensory perception GO:0007600 196 0.255
regulation of axon extension involved in axon guidance GO:0048841 4 0.244
Mouse
muscle cell differentiation GO:0042692 103 0.235
positive regulation of macromolecule metabolic process GO:0010604 405 0.209
single organism behavior GO:0044708 391 0.204
Fly
regulation of axonogenesis GO:0050770 32 0.203
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.192
cognition GO:0050890 141 0.191
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.175
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.175
chemotaxis GO:0006935 249 0.175
regulation of neuron projection development GO:0010975 69 0.172
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.168
telencephalon development GO:0021537 2 0.167
Mouse
negative regulation of gene expression GO:0010629 387 0.164
negative regulation of rna biosynthetic process GO:1902679 240 0.164
phosphorylation GO:0016310 294 0.161
Human Fly
protein phosphorylation GO:0006468 169 0.161
Fly
cell growth GO:0016049 108 0.155
Mouse
regulation of neurogenesis GO:0050767 158 0.154
Mouse
developmental cell growth GO:0048588 52 0.152
Mouse
exocrine system development GO:0035272 162 0.152
regulation of cell development GO:0060284 215 0.150
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.149
regulation of nervous system development GO:0051960 248 0.147
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.146
cell migration GO:0016477 238 0.146
Zebrafish
chemosensory behavior GO:0007635 106 0.145
Fly
motor neuron axon guidance GO:0008045 58 0.137
brain development GO:0007420 120 0.136
Mouse
positive regulation of nucleoside metabolic process GO:0045979 47 0.131
regulation of cellular component size GO:0032535 98 0.129
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.127
dendrite development GO:0016358 204 0.127
negative regulation of cellular metabolic process GO:0031324 382 0.125
salivary gland development GO:0007431 162 0.124
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.123
Mouse
positive regulation of cell growth GO:0030307 19 0.122
regulation of extent of cell growth GO:0061387 8 0.121
Mouse
epithelial cell differentiation GO:0030855 322 0.118
regulation of phosphorylation GO:0042325 147 0.115
Human
regulation of anatomical structure size GO:0090066 163 0.113
Mouse
regulation of developmental growth GO:0048638 174 0.112
Mouse
central nervous system development GO:0007417 201 0.108
Mouse
negative regulation of response to stimulus GO:0048585 258 0.108
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.107
forebrain development GO:0030900 2 0.105
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.105
regulation of behavior GO:0050795 75 0.104
Mouse
regulation of localization GO:0032879 275 0.103
Zebrafish Mouse
negative regulation of cellular component organization GO:0051129 108 0.103
Mouse
regulation of multicellular organismal development GO:2000026 414 0.100
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.100
embryonic development via the syncytial blastoderm GO:0001700 148 0.097
neuron projection guidance GO:0097485 241 0.095
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.094
cell cell signaling involved in cell fate commitment GO:0045168 210 0.094
Fly
dendrite morphogenesis GO:0048813 199 0.093
nucleobase containing small molecule metabolic process GO:0055086 174 0.092
ribonucleotide metabolic process GO:0009259 145 0.091
mapk cascade GO:0000165 107 0.090
Human
positive regulation of cell communication GO:0010647 250 0.089
Human
negative regulation of growth GO:0045926 84 0.089
Mouse
salivary gland morphogenesis GO:0007435 145 0.086
sensory perception of smell GO:0007608 80 0.086
gland development GO:0048732 191 0.085
dendrite guidance GO:0070983 21 0.084
negative regulation of cell differentiation GO:0045596 143 0.083
Mouse
regionalization GO:0003002 416 0.082
regulation of cell differentiation GO:0045595 302 0.081
Mouse
positive regulation of growth GO:0045927 75 0.080
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.080
compound eye development GO:0048749 307 0.078
intracellular signal transduction GO:0035556 300 0.078
Human
regulation of axon extension GO:0030516 8 0.076
Mouse
purine nucleotide catabolic process GO:0006195 109 0.073
positive regulation of rho gtpase activity GO:0032321 19 0.072
embryo development ending in birth or egg hatching GO:0009792 152 0.072
purine containing compound metabolic process GO:0072521 155 0.071
detection of abiotic stimulus GO:0009582 66 0.071
organonitrogen compound metabolic process GO:1901564 318 0.070
positive regulation of cell motility GO:2000147 3 0.069
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
signal transduction by phosphorylation GO:0023014 107 0.068
Human
regulation of intracellular signal transduction GO:1902531 236 0.068
Human
regulation of phosphorus metabolic process GO:0051174 210 0.067
Human
negative regulation of nervous system development GO:0051961 92 0.066
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.065
organophosphate metabolic process GO:0019637 195 0.064
positive regulation of cellular protein metabolic process GO:0032270 118 0.063
digestive system development GO:0055123 149 0.062
Zebrafish
positive regulation of nucleotide catabolic process GO:0030813 46 0.062
rho protein signal transduction GO:0007266 14 0.062
purine nucleotide metabolic process GO:0006163 146 0.062
cell death GO:0008219 279 0.061
purine ribonucleoside metabolic process GO:0046128 127 0.061
localization of cell GO:0051674 257 0.061
Zebrafish
positive regulation of phosphorylation GO:0042327 87 0.060
Human
multi organism behavior GO:0051705 175 0.060
compound eye morphogenesis GO:0001745 249 0.060
neuron recognition GO:0008038 101 0.060
immune system process GO:0002376 347 0.059
regulation of anatomical structure morphogenesis GO:0022603 242 0.058
Mouse
regulation of cell growth GO:0001558 43 0.058
Mouse
catabolic process GO:0009056 409 0.058
regulation of cellular component movement GO:0051270 42 0.058
Mouse
programmed cell death GO:0012501 257 0.057
axon guidance GO:0007411 233 0.057
lateral inhibition GO:0046331 206 0.057
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.057
eye photoreceptor cell differentiation GO:0001754 145 0.057
eye development GO:0001654 323 0.056
regulation of ras gtpase activity GO:0032318 38 0.056
regulation of phosphate metabolic process GO:0019220 210 0.055
Human
regulation of mapk cascade GO:0043408 92 0.055
Human
dephosphorylation GO:0016311 51 0.054
oocyte development GO:0048599 124 0.054
nucleoside catabolic process GO:0009164 112 0.053
positive regulation of cellular component organization GO:0051130 156 0.053
regulation of protein phosphorylation GO:0001932 64 0.053
organic substance catabolic process GO:1901575 308 0.053
compound eye photoreceptor cell differentiation GO:0001751 140 0.053
photoreceptor cell differentiation GO:0046530 170 0.053
ras protein signal transduction GO:0007265 88 0.053
nucleotide metabolic process GO:0009117 161 0.052
negative regulation of programmed cell death GO:0043069 72 0.052
positive regulation of signaling GO:0023056 243 0.052
Human
negative regulation of axon extension GO:0030517 3 0.052
Mouse
response to biotic stimulus GO:0009607 294 0.051
glycosyl compound catabolic process GO:1901658 112 0.051
ribose phosphate metabolic process GO:0019693 145 0.051
protein modification process GO:0036211 438 0.051
Fly
positive regulation of gtp catabolic process GO:0033126 43 0.050
cellular protein modification process GO:0006464 438 0.050
Fly
positive regulation of response to stimulus GO:0048584 323 0.050
Human
positive regulation of signal transduction GO:0009967 223 0.049
Human
regulation of cell shape GO:0008360 113 0.049
sensory organ morphogenesis GO:0090596 260 0.048
regulation of response to external stimulus GO:0032101 115 0.048
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.047
sensory perception of chemical stimulus GO:0007606 116 0.047
positive regulation of phosphorus metabolic process GO:0010562 139 0.047
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.046
transmembrane transport GO:0055085 139 0.046
small gtpase mediated signal transduction GO:0007264 88 0.045
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.045
macromolecular complex assembly GO:0065003 256 0.045
response to organic substance GO:0010033 284 0.045
segmentation GO:0035282 207 0.045
regulation of multi organism process GO:0043900 131 0.045
positive regulation of catabolic process GO:0009896 105 0.044
regulation of rho gtpase activity GO:0032319 20 0.044
gland morphogenesis GO:0022612 145 0.044
aromatic compound catabolic process GO:0019439 166 0.044
response to other organism GO:0051707 293 0.044
morphogenesis of an epithelium GO:0002009 276 0.043
Zebrafish
regulation of cell projection organization GO:0031344 92 0.043
Mouse
glycosyl compound metabolic process GO:1901657 127 0.043
epithelial cell development GO:0002064 274 0.043
learning or memory GO:0007611 141 0.043
Fly
guanosine containing compound catabolic process GO:1901069 74 0.043
positive regulation of protein metabolic process GO:0051247 128 0.043
apoptotic process GO:0006915 159 0.042
neuron fate commitment GO:0048663 50 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.042
synaptic target recognition GO:0008039 45 0.042
cell division GO:0051301 248 0.042
positive regulation of axonogenesis GO:0050772 2 0.042
regulation of nucleoside metabolic process GO:0009118 50 0.041
positive regulation of nucleotide metabolic process GO:0045981 55 0.041
tissue morphogenesis GO:0048729 297 0.041
Zebrafish
nucleotide catabolic process GO:0009166 109 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
eye photoreceptor cell fate commitment GO:0042706 37 0.040
ion transmembrane transport GO:0034220 122 0.040
regulation of cell death GO:0010941 173 0.040
guanosine containing compound metabolic process GO:1901068 74 0.040
purine nucleoside metabolic process GO:0042278 127 0.040
regulation of protein modification process GO:0031399 112 0.040
positive regulation of developmental process GO:0051094 143 0.040
negative regulation of neurogenesis GO:0050768 53 0.040
Mouse
positive regulation of protein modification process GO:0031401 58 0.040
single organismal cell cell adhesion GO:0016337 45 0.040
ribonucleoside triphosphate catabolic process GO:0009203 108 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.039
male mating behavior GO:0060179 70 0.039
regulation of protein metabolic process GO:0051246 256 0.039
ribonucleoside metabolic process GO:0009119 127 0.039
positive regulation of mapk cascade GO:0043410 63 0.038
Human
negative regulation of cell communication GO:0010648 223 0.038
ribonucleoside catabolic process GO:0042454 112 0.038
regulation of antimicrobial peptide production GO:0002784 44 0.038
associative learning GO:0008306 65 0.038
Fly
regulation of cellular response to stress GO:0080135 89 0.038
positive regulation of gene expression GO:0010628 290 0.038
mating GO:0007618 120 0.038
blastoderm segmentation GO:0007350 159 0.038
positive regulation of nervous system development GO:0051962 69 0.037
carbohydrate derivative catabolic process GO:1901136 118 0.036
appendage morphogenesis GO:0035107 397 0.036
single organism biosynthetic process GO:0044711 206 0.036
cellular catabolic process GO:0044248 372 0.036
imaginal disc derived appendage morphogenesis GO:0035114 395 0.036
gtp metabolic process GO:0046039 72 0.036
growth GO:0040007 359 0.036
Zebrafish Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.036
negative regulation of phosphate metabolic process GO:0045936 45 0.035
photoreceptor cell fate commitment GO:0046552 41 0.035
detection of stimulus involved in sensory perception GO:0050906 92 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.035
dna metabolic process GO:0006259 227 0.035
mushroom body development GO:0016319 70 0.035
long term memory GO:0007616 62 0.035
detection of stimulus GO:0051606 156 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.034
cellular nitrogen compound catabolic process GO:0044270 165 0.034
cell motility GO:0048870 251 0.034
Zebrafish
purine ribonucleotide catabolic process GO:0009154 109 0.034
compound eye photoreceptor fate commitment GO:0001752 36 0.034
nucleoside triphosphate catabolic process GO:0009143 108 0.034
positive regulation of catalytic activity GO:0043085 118 0.034
regulation of dendrite development GO:0050773 37 0.034
positive regulation of gtpase activity GO:0043547 43 0.034
embryonic morphogenesis GO:0048598 206 0.034
Zebrafish
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.034
membrane depolarization GO:0051899 4 0.034
epithelial tube morphogenesis GO:0060562 88 0.034
nucleoside triphosphate metabolic process GO:0009141 120 0.034
intracellular transport GO:0046907 228 0.034
Zebrafish
positive regulation of ras gtpase activity GO:0032320 36 0.034
mating behavior GO:0007617 106 0.034
regulation of gtp catabolic process GO:0033124 44 0.033
positive regulation of neurogenesis GO:0050769 41 0.033
purine nucleoside triphosphate metabolic process GO:0009144 119 0.033
olfactory behavior GO:0042048 97 0.032
Fly
gtp catabolic process GO:0006184 72 0.032
malpighian tubule development GO:0072002 64 0.032
response to inorganic substance GO:0010035 44 0.032
axon extension involved in axon guidance GO:0048846 10 0.031
Mouse
tube morphogenesis GO:0035239 191 0.031
Zebrafish
heterocycle catabolic process GO:0046700 166 0.031
columnar cuboidal epithelial cell development GO:0002066 249 0.031
regulation of catabolic process GO:0009894 170 0.031
renal system development GO:0072001 72 0.031
death GO:0016265 284 0.031
positive regulation of biosynthetic process GO:0009891 316 0.030
negative regulation of cell development GO:0010721 62 0.030
Mouse
immune response GO:0006955 246 0.030
regulation of response to stress GO:0080134 200 0.030
positive regulation of molecular function GO:0044093 136 0.029
regulation of apoptotic process GO:0042981 130 0.029
regulation of rho protein signal transduction GO:0035023 20 0.029
retina development in camera type eye GO:0060041 4 0.029
regulation of purine nucleotide metabolic process GO:1900542 62 0.029
purine containing compound catabolic process GO:0072523 112 0.028
malpighian tubule morphogenesis GO:0007443 44 0.028
regulation of cell cycle GO:0051726 291 0.028
ribonucleotide catabolic process GO:0009261 109 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
negative regulation of apoptotic process GO:0043066 63 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.028
imaginal disc derived appendage development GO:0048737 399 0.028
Fly
positive regulation of cell migration GO:0030335 2 0.028
sensory perception of mechanical stimulus GO:0050954 72 0.027
regulation of gtpase activity GO:0043087 44 0.027
nucleoside metabolic process GO:0009116 127 0.027
positive regulation of cellular catabolic process GO:0031331 95 0.027
embryonic hindgut morphogenesis GO:0048619 48 0.027
positive regulation of cell projection organization GO:0031346 29 0.027
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
single organism catabolic process GO:0044712 228 0.027
eye morphogenesis GO:0048592 260 0.026
positive regulation of programmed cell death GO:0043068 62 0.026
formation of organ boundary GO:0010160 30 0.026
memory GO:0007613 94 0.026
Fly
regulation of neuron differentiation GO:0045664 103 0.026
Mouse
organic substance transport GO:0071702 257 0.025
anterior posterior pattern specification GO:0009952 136 0.025
regulation of nucleotide catabolic process GO:0030811 48 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
negative regulation of cell death GO:0060548 81 0.025
regulation of synapse structure and activity GO:0050803 128 0.025
stress activated mapk cascade GO:0051403 52 0.025
eggshell formation GO:0030703 105 0.025
developmental maturation GO:0021700 172 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
single organism cell adhesion GO:0098602 47 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
tube development GO:0035295 244 0.024
Zebrafish
positive regulation of intracellular signal transduction GO:1902533 116 0.024
Human
regulation of dendrite morphogenesis GO:0048814 28 0.024
small molecule metabolic process GO:0044281 305 0.024
regulation of hydrolase activity GO:0051336 97 0.024
single organism intracellular transport GO:1902582 207 0.024
Zebrafish
antimicrobial humoral response GO:0019730 99 0.024
stress activated protein kinase signaling cascade GO:0031098 55 0.024
purine nucleoside triphosphate catabolic process GO:0009146 108 0.024
cell recognition GO:0008037 102 0.024
response to organophosphorus GO:0046683 2 0.024
regulation of molecular function GO:0065009 217 0.024
regulation of ras protein signal transduction GO:0046578 93 0.024
nucleoside phosphate catabolic process GO:1901292 110 0.024
eye antennal disc development GO:0035214 60 0.024
purine nucleoside catabolic process GO:0006152 112 0.023
anterior posterior axis specification GO:0009948 109 0.023
establishment of localization in cell GO:0051649 402 0.023
Zebrafish
embryonic axis specification GO:0000578 107 0.023
cytosolic calcium ion transport GO:0060401 2 0.023
Zebrafish
negative regulation of signaling GO:0023057 219 0.023
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.023
divalent metal ion transport GO:0070838 26 0.023
Zebrafish
response to external biotic stimulus GO:0043207 293 0.022
phosphatidylinositol mediated signaling GO:0048015 4 0.022
protein complex biogenesis GO:0070271 201 0.022
protein localization GO:0008104 284 0.022
multi organism reproductive behavior GO:0044705 121 0.022
olfactory learning GO:0008355 56 0.022
Fly
body morphogenesis GO:0010171 2 0.022
cell adhesion GO:0007155 136 0.021
cell fate specification GO:0001708 71 0.021
positive regulation of hydrolase activity GO:0051345 78 0.021
regulation of stress activated mapk cascade GO:0032872 41 0.021
organophosphate catabolic process GO:0046434 112 0.021
mitotic nuclear division GO:0007067 213 0.021
regulation of programmed cell death GO:0043067 152 0.021
anterior posterior axis specification embryo GO:0008595 103 0.021
regulation of axon guidance GO:1902667 10 0.021
Mouse
peptide biosynthetic process GO:0043043 42 0.021
positive regulation of cell differentiation GO:0045597 64 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
regulation of nucleotide metabolic process GO:0006140 62 0.021
negative regulation of signal transduction GO:0009968 206 0.021
reproductive behavior GO:0019098 122 0.020
humoral immune response GO:0006959 117 0.020
urogenital system development GO:0001655 72 0.020
appendage development GO:0048736 401 0.020
Fly
hindbrain development GO:0030902 2 0.020
regulation of immune response GO:0050776 118 0.020
homeostatic process GO:0042592 199 0.020
Zebrafish
embryonic pattern specification GO:0009880 174 0.020
cell maturation GO:0048469 144 0.020
organonitrogen compound catabolic process GO:1901565 128 0.019
neural precursor cell proliferation GO:0061351 75 0.019
ion transport GO:0006811 145 0.019
Zebrafish
regulation of mitotic cell cycle GO:0007346 190 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
defense response to bacterium GO:0042742 178 0.019
hindgut morphogenesis GO:0007442 58 0.018
regulation of chemotaxis GO:0050920 12 0.018
Mouse
kidney development GO:0001822 3 0.018
regulation of membrane potential GO:0042391 35 0.018
positive regulation of neuron differentiation GO:0045666 26 0.018
protein complex assembly GO:0006461 200 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
convergent extension GO:0060026 2 0.018
Zebrafish
learning GO:0007612 75 0.018
Fly
male courtship behavior GO:0008049 63 0.017
detection of chemical stimulus GO:0009593 93 0.017
negative regulation of homeostatic process GO:0032845 2 0.017
Zebrafish
negative regulation of molecular function GO:0044092 51 0.017
metal ion transport GO:0030001 74 0.017
Zebrafish
wing disc morphogenesis GO:0007472 344 0.017
muscle organ development GO:0007517 127 0.017
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.017
l glutamate import GO:0051938 1 0.017
ovarian follicle cell development GO:0030707 248 0.017
positive regulation of protein phosphorylation GO:0001934 34 0.017
tripartite regional subdivision GO:0007351 103 0.017
larval development GO:0002164 104 0.017
regulation of cellular component biogenesis GO:0044087 201 0.016
digestive tract development GO:0048565 149 0.016
Zebrafish
regulation of ion transport GO:0043269 39 0.016
salt aversion GO:0035199 3 0.016
response to oxygen containing compound GO:1901700 200 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
response to organonitrogen compound GO:0010243 75 0.016
response to alcohol GO:0097305 95 0.016
sensory perception of pain GO:0019233 4 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
hindgut development GO:0061525 58 0.016
response to ethanol GO:0045471 59 0.016
gliogenesis GO:0042063 80 0.016
wnt signaling pathway GO:0016055 98 0.016
renal tubule morphogenesis GO:0061333 44 0.016
cell fate determination GO:0001709 91 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
negative regulation of developmental growth GO:0048640 64 0.015
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
axis specification GO:0009798 167 0.015
regulation of immune system process GO:0002682 176 0.015
inorganic cation transmembrane transport GO:0098662 61 0.015
response to abiotic stimulus GO:0009628 341 0.015
neuronal stem cell division GO:0036445 35 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
inositol lipid mediated signaling GO:0048017 4 0.015
positive regulation of cell development GO:0010720 61 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
release of sequestered calcium ion into cytosol GO:0051209 1 0.014
Zebrafish
vesicle mediated transport GO:0016192 381 0.014
positive regulation of synapse assembly GO:0051965 29 0.014
regulation of reproductive process GO:2000241 54 0.014
regulation of endocytosis GO:0030100 37 0.014
pole plasm assembly GO:0007315 61 0.014
mesoderm development GO:0007498 78 0.014
digestive tract morphogenesis GO:0048546 127 0.014
Zebrafish
cell type specific apoptotic process GO:0097285 38 0.014
phagocytosis GO:0006909 215 0.014
gastrulation GO:0007369 70 0.014
Zebrafish
antennal joint development GO:0048098 5 0.013
cellular homeostasis GO:0019725 80 0.013
Zebrafish
positive regulation of neuron projection development GO:0010976 14 0.013
response to decreased oxygen levels GO:0036293 58 0.013
positive regulation of organelle organization GO:0010638 65 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
detection of external stimulus GO:0009581 66 0.013
protein transport GO:0015031 155 0.013
chorion containing eggshell formation GO:0007304 105 0.013
amino acid transport GO:0006865 12 0.013
camera type eye development GO:0043010 4 0.013
gene silencing GO:0016458 138 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
regulation of synaptic transmission GO:0050804 69 0.013
nephron development GO:0072006 3 0.013
striated muscle cell differentiation GO:0051146 90 0.013
regulation of organelle organization GO:0033043 196 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.012
Human
regulation of antimicrobial humoral response GO:0002759 50 0.012
cell proliferation GO:0008283 299 0.012
positive regulation of developmental growth GO:0048639 62 0.012
respiratory system development GO:0060541 213 0.012
defense response GO:0006952 300 0.012
defense response to other organism GO:0098542 225 0.012
amide biosynthetic process GO:0043604 42 0.012
lymph gland development GO:0048542 28 0.012
response to wounding GO:0009611 94 0.012
response to mechanical stimulus GO:0009612 28 0.012
regulation of neuron death GO:1901214 26 0.012
peptidyl amino acid modification GO:0018193 105 0.012
Fly
neuron death GO:0070997 27 0.011
germ cell migration GO:0008354 43 0.011
morphogenesis of a branching epithelium GO:0061138 45 0.011
regulation of sequestering of calcium ion GO:0051282 3 0.011
Zebrafish
sensory perception of salty taste GO:0050914 3 0.011
regulation of response to dna damage stimulus GO:2001020 23 0.011
regulation of actin filament based process GO:0032970 42 0.011
sex differentiation GO:0007548 81 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
branching morphogenesis of an epithelial tube GO:0048754 45 0.011
positive regulation of axon extension GO:0045773 2 0.011
regulation of cell adhesion GO:0030155 27 0.011
single organism membrane organization GO:0044802 93 0.011
regulation of actin cytoskeleton organization GO:0032956 42 0.011
receptor clustering GO:0043113 3 0.010
regulation of cellular localization GO:0060341 136 0.010
response to sterol GO:0036314 34 0.010
regulation of cell cycle process GO:0010564 181 0.010
organic anion transport GO:0015711 28 0.010
endomembrane system organization GO:0010256 119 0.010
morphogenesis of a polarized epithelium GO:0001738 93 0.010
metal ion homeostasis GO:0055065 44 0.010
Zebrafish
mechanosensory behavior GO:0007638 12 0.010

Drl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.120
sensory system disease DOID:0050155 0 0.036
eye and adnexa disease DOID:1492 0 0.036
nervous system disease DOID:863 0 0.036
eye disease DOID:5614 0 0.029