Drosophila melanogaster

27 known processes

tweek (Dmel_CG42555)

CG42555 gene product from transcript CG42555-RD

(Aliases: CG4841,CG42555,Dmel\CG42555,CG42706,Dmel_CG4841,CG15133,Dmel_CG15134,Dmel_CG15133,CG15134)

tweek biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.856
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.402
positive regulation of gene expression GO:0010628 290 0.343
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.314
negative regulation of biosynthetic process GO:0009890 277 0.292
positive regulation of cellular biosynthetic process GO:0031328 316 0.286
positive regulation of nucleic acid templated transcription GO:1903508 266 0.286
neuron neuron synaptic transmission GO:0007270 14 0.285
detection of stimulus GO:0051606 156 0.274
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.260
regulation of gene expression epigenetic GO:0040029 128 0.242
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.241
negative regulation of nucleic acid templated transcription GO:1903507 240 0.237
sensory perception GO:0007600 196 0.224
feeding behavior GO:0007631 50 0.222
positive regulation of transcription dna templated GO:0045893 266 0.214
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.205
negative regulation of cellular metabolic process GO:0031324 382 0.200
regulation of cell death GO:0010941 173 0.180
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.168
positive regulation of biosynthetic process GO:0009891 316 0.153
mating GO:0007618 120 0.151
negative regulation of rna biosynthetic process GO:1902679 240 0.141
negative regulation of rna metabolic process GO:0051253 251 0.134
negative regulation of gene expression GO:0010629 387 0.131
positive regulation of rna metabolic process GO:0051254 271 0.128
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.117
cell proliferation GO:0008283 299 0.117
gene silencing GO:0016458 138 0.110
endocytosis GO:0006897 310 0.106
posttranscriptional regulation of gene expression GO:0010608 145 0.104
neural precursor cell proliferation GO:0061351 75 0.099
positive regulation of cellular component organization GO:0051130 156 0.091
taxis GO:0042330 304 0.085
regulation of multi organism process GO:0043900 131 0.082
stem cell maintenance GO:0019827 67 0.080
negative regulation of cellular biosynthetic process GO:0031327 277 0.077
cell death GO:0008219 279 0.072
vesicle organization GO:0016050 44 0.068
negative regulation of transcription dna templated GO:0045892 237 0.068
cellular response to chemical stimulus GO:0070887 199 0.066
forebrain development GO:0030900 2 0.063
homeostatic process GO:0042592 199 0.062
negative regulation of multicellular organismal process GO:0051241 142 0.059
telencephalon development GO:0021537 2 0.058
organelle localization GO:0051640 148 0.058
regulation of response to external stimulus GO:0032101 115 0.058
establishment of organelle localization GO:0051656 122 0.057
positive regulation of response to stimulus GO:0048584 323 0.057
establishment of localization in cell GO:0051649 402 0.057
neuromuscular synaptic transmission GO:0007274 67 0.054
signal release GO:0023061 49 0.053
segmentation GO:0035282 207 0.052
death GO:0016265 284 0.052
regulation of cell proliferation GO:0042127 163 0.052
vesicle mediated transport GO:0016192 381 0.050
negative regulation of cell differentiation GO:0045596 143 0.049
positive regulation of rna biosynthetic process GO:1902680 266 0.048
response to organic substance GO:0010033 284 0.048
regulation of programmed cell death GO:0043067 152 0.048
rna localization GO:0006403 115 0.048
synaptic vesicle endocytosis GO:0048488 28 0.047
peptide metabolic process GO:0006518 80 0.047
blastoderm segmentation GO:0007350 159 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.046
neuromuscular junction development GO:0007528 149 0.044
secretion GO:0046903 109 0.044
ion homeostasis GO:0050801 55 0.044
adult locomotory behavior GO:0008344 76 0.043
chemical homeostasis GO:0048878 92 0.043
chemotaxis GO:0006935 249 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
cell maturation GO:0048469 144 0.039
digestive system development GO:0055123 149 0.039
developmental maturation GO:0021700 172 0.038
gene silencing by rna GO:0031047 57 0.038
regulation of endocytosis GO:0030100 37 0.038
locomotory behavior GO:0007626 176 0.038
synaptic vesicle recycling GO:0036465 28 0.037
neurotransmitter secretion GO:0007269 35 0.037
chromosome organization GO:0051276 360 0.037
digestive tract morphogenesis GO:0048546 127 0.036
neuron maturation GO:0042551 31 0.036
posttranscriptional gene silencing by rna GO:0035194 45 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
synaptic growth at neuromuscular junction GO:0051124 119 0.035
cellular catabolic process GO:0044248 372 0.034
small molecule metabolic process GO:0044281 305 0.034
response to abiotic stimulus GO:0009628 341 0.033
positive regulation of cell communication GO:0010647 250 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
photoreceptor cell differentiation GO:0046530 170 0.033
positive regulation of signal transduction GO:0009967 223 0.033
response to hormone GO:0009725 45 0.033
endomembrane system organization GO:0010256 119 0.033
axon guidance GO:0007411 233 0.032
response to reactive oxygen species GO:0000302 24 0.032
response to organic cyclic compound GO:0014070 89 0.032
regulation of catabolic process GO:0009894 170 0.032
muscle organ development GO:0007517 127 0.032
tissue migration GO:0090130 155 0.031
digestive tract development GO:0048565 149 0.031
covalent chromatin modification GO:0016569 106 0.031
response to biotic stimulus GO:0009607 294 0.031
catabolic process GO:0009056 409 0.031
synaptic vesicle transport GO:0048489 50 0.031
organic substance catabolic process GO:1901575 308 0.030
regulation of cell cycle GO:0051726 291 0.030
protein modification process GO:0036211 438 0.030
synaptic vesicle exocytosis GO:0016079 16 0.030
response to lipid GO:0033993 38 0.029
r7 cell differentiation GO:0045466 43 0.029
immune system process GO:0002376 347 0.028
epithelium migration GO:0090132 148 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
gastrulation GO:0007369 70 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
chromosome segregation GO:0007059 157 0.026
cellular amide metabolic process GO:0043603 80 0.026
ion transport GO:0006811 145 0.026
tissue morphogenesis GO:0048729 297 0.025
cell fate specification GO:0001708 71 0.025
response to salt stress GO:0009651 11 0.025
secretion by cell GO:0032940 101 0.024
synaptic vesicle localization GO:0097479 53 0.024
cellular response to endogenous stimulus GO:0071495 80 0.024
mitotic sister chromatid segregation GO:0000070 87 0.024
synapse assembly GO:0007416 143 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
positive regulation of transport GO:0051050 92 0.023
cell cycle phase transition GO:0044770 140 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
regulation of growth GO:0040008 233 0.023
response to oxygen levels GO:0070482 59 0.023
cation homeostasis GO:0055080 51 0.023
positive regulation of cell death GO:0010942 69 0.023
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.023
stem cell differentiation GO:0048863 117 0.023
multi multicellular organism process GO:0044706 123 0.023
exocytosis GO:0006887 28 0.022
eye photoreceptor cell differentiation GO:0001754 145 0.022
mesenchymal cell differentiation GO:0048762 1 0.022
positive regulation of cell migration GO:0030335 2 0.022
mating behavior GO:0007617 106 0.022
response to oxygen containing compound GO:1901700 200 0.022
multi organism behavior GO:0051705 175 0.022
photoreceptor cell fate commitment GO:0046552 41 0.022
negative regulation of growth GO:0045926 84 0.022
cellular macromolecular complex assembly GO:0034622 153 0.022
organelle fission GO:0048285 340 0.021
defense response to other organism GO:0098542 225 0.021
regulation of feeding behavior GO:0060259 16 0.021
regulation of cell cycle process GO:0010564 181 0.021
regulation of epithelial cell proliferation GO:0050678 4 0.021
oocyte differentiation GO:0009994 145 0.020
cation transport GO:0006812 110 0.020
positive regulation of cell motility GO:2000147 3 0.020
phototaxis GO:0042331 21 0.020
response to starvation GO:0042594 97 0.019
developmental pigmentation GO:0048066 68 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
l glutamate import GO:0051938 1 0.019
response to endogenous stimulus GO:0009719 119 0.019
mitotic nuclear division GO:0007067 213 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
macromolecular complex assembly GO:0065003 256 0.019
epithelial cell migration GO:0010631 148 0.019
mesenchymal cell development GO:0014031 1 0.018
gliogenesis GO:0042063 80 0.018
establishment of synaptic vesicle localization GO:0097480 50 0.018
synapse organization GO:0050808 196 0.018
response to lipopolysaccharide GO:0032496 4 0.018
eye morphogenesis GO:0048592 260 0.018
regulation of cell growth GO:0001558 43 0.018
mitotic spindle organization GO:0007052 220 0.018
cytoplasm organization GO:0007028 64 0.018
sensory perception of chemical stimulus GO:0007606 116 0.018
neurotransmitter transport GO:0006836 37 0.018
cell adhesion GO:0007155 136 0.018
cellular lipid metabolic process GO:0044255 83 0.018
cell cycle checkpoint GO:0000075 95 0.018
neuron fate commitment GO:0048663 50 0.017
gland morphogenesis GO:0022612 145 0.017
programmed cell death GO:0012501 257 0.017
establishment of vesicle localization GO:0051650 51 0.017
tube development GO:0035295 244 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
carbohydrate metabolic process GO:0005975 82 0.017
growth GO:0040007 359 0.017
camera type eye development GO:0043010 4 0.017
response to light stimulus GO:0009416 124 0.017
metal ion homeostasis GO:0055065 44 0.017
positive regulation of cell proliferation GO:0008284 47 0.016
positive regulation of signaling GO:0023056 243 0.016
imaginal disc pattern formation GO:0007447 91 0.016
vesicle localization GO:0051648 55 0.016
muscle tissue development GO:0060537 30 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
macromolecule catabolic process GO:0009057 161 0.016
protein localization GO:0008104 284 0.016
morphogenesis of an epithelium GO:0002009 276 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
cellular hormone metabolic process GO:0034754 23 0.015
regulation of neuron differentiation GO:0045664 103 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
regulation of membrane potential GO:0042391 35 0.015
epithelial cell differentiation GO:0030855 322 0.015
sister chromatid segregation GO:0000819 92 0.015
tripartite regional subdivision GO:0007351 103 0.015
regulation of hydrolase activity GO:0051336 97 0.014
detection of chemical stimulus GO:0009593 93 0.014
response to bacterium GO:0009617 198 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
detection of abiotic stimulus GO:0009582 66 0.014
regulation of cell differentiation GO:0045595 302 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
nucleoside catabolic process GO:0009164 112 0.013
embryonic morphogenesis GO:0048598 206 0.013
cellular homeostasis GO:0019725 80 0.013
heart process GO:0003015 37 0.013
response to other organism GO:0051707 293 0.013
glycerolipid metabolic process GO:0046486 34 0.013
body morphogenesis GO:0010171 2 0.013
regulation of reproductive process GO:2000241 54 0.013
negative regulation of nervous system development GO:0051961 92 0.013
compound eye photoreceptor fate commitment GO:0001752 36 0.013
translation GO:0006412 69 0.013
positive regulation of growth GO:0045927 75 0.013
regulation of response to stress GO:0080134 200 0.012
anatomical structure homeostasis GO:0060249 97 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
regulation of receptor mediated endocytosis GO:0048259 9 0.012
skeletal muscle tissue development GO:0007519 13 0.012
single organism intracellular transport GO:1902582 207 0.012
organelle fusion GO:0048284 46 0.012
regulation of transport GO:0051049 181 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
membrane budding GO:0006900 4 0.012
regulation of secretion GO:0051046 44 0.012
response to ketone GO:1901654 34 0.012
amine metabolic process GO:0009308 12 0.012
protein catabolic process GO:0030163 101 0.012
wing disc morphogenesis GO:0007472 344 0.012
positive regulation of cell cycle GO:0045787 43 0.012
regulation of immune system process GO:0002682 176 0.012
wing disc pattern formation GO:0035222 66 0.012
response to external biotic stimulus GO:0043207 293 0.012
developmental growth GO:0048589 280 0.012
anterior posterior pattern specification GO:0009952 136 0.012
regulation of cellular localization GO:0060341 136 0.011
response to radiation GO:0009314 155 0.011
nitrogen compound transport GO:0071705 85 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
defense response to bacterium GO:0042742 178 0.011
neuroblast differentiation GO:0014016 29 0.011
hindbrain development GO:0030902 2 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of neurotransmitter levels GO:0001505 38 0.011
single organism membrane organization GO:0044802 93 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
stem cell development GO:0048864 79 0.011
energy taxis GO:0009453 21 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
anterior posterior axis specification GO:0009948 109 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
regulation of neuron death GO:1901214 26 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
formation of primary germ layer GO:0001704 24 0.011
regulation of localization GO:0032879 275 0.011
regulation of behavior GO:0050795 75 0.011
protein complex assembly GO:0006461 200 0.011
chaeta development GO:0022416 97 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
response to hypoxia GO:0001666 53 0.011
r3 r4 cell differentiation GO:0048056 12 0.011
response to decreased oxygen levels GO:0036293 58 0.010
determination of adult lifespan GO:0008340 137 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
dorsal closure GO:0007391 79 0.010
nuclear division GO:0000280 332 0.010
dna integrity checkpoint GO:0031570 81 0.010
nucleus localization GO:0051647 34 0.010
neuronal stem cell maintenance GO:0097150 4 0.010

tweek disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
disease of metabolism DOID:0014667 0 0.052
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
carbohydrate metabolism disease DOID:0050013 0 0.030
acquired metabolic disease DOID:0060158 0 0.030
inherited metabolic disorder DOID:655 0 0.018
organ system cancer DOID:0050686 0 0.018
nervous system disease DOID:863 0 0.013