Drosophila melanogaster

43 known processes

Vha16 (Dmel_CG3161)

Vacuolar H[+] ATPase 16kD subunit

(Aliases: vha16-1,Vha1,EP2372,vha16,Vhac,CG3161,Dmel\CG3161,V-ATPase,BcDNA:SD02875,DucC)

Vha16 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
death GO:0016265 284 0.363
programmed cell death GO:0012501 257 0.325
multicellular organismal aging GO:0010259 140 0.296
intracellular transport GO:0046907 228 0.296
lipid storage GO:0019915 38 0.258
ph reduction GO:0045851 7 0.226
negative regulation of gene expression GO:0010629 387 0.194
aging GO:0007568 143 0.190
organic substance transport GO:0071702 257 0.188
purine containing compound metabolic process GO:0072521 155 0.183
lipid localization GO:0010876 54 0.181
cellular macromolecule localization GO:0070727 220 0.179
determination of adult lifespan GO:0008340 137 0.172
nucleobase containing small molecule metabolic process GO:0055086 174 0.170
cell death GO:0008219 279 0.153
regulation of cell differentiation GO:0045595 302 0.143
embryo development ending in birth or egg hatching GO:0009792 152 0.143
developmental growth GO:0048589 280 0.142
regulation of multicellular organismal development GO:2000026 414 0.135
single organism intracellular transport GO:1902582 207 0.134
establishment of protein localization GO:0045184 163 0.127
regulation of cell death GO:0010941 173 0.126
response to abiotic stimulus GO:0009628 341 0.125
vesicle mediated transport GO:0016192 381 0.121
Fly
protein transport GO:0015031 155 0.113
protein complex assembly GO:0006461 200 0.111
ion transport GO:0006811 145 0.111
single organism cellular localization GO:1902580 180 0.107
endocytosis GO:0006897 310 0.106
Fly
spermatogenesis GO:0007283 200 0.105
monovalent inorganic cation transport GO:0015672 40 0.105
establishment of localization in cell GO:0051649 402 0.101
cellular protein localization GO:0034613 160 0.098
growth GO:0040007 359 0.097
post embryonic appendage morphogenesis GO:0035120 385 0.097
telencephalon development GO:0021537 2 0.096
intracellular protein transport GO:0006886 104 0.093
nucleoside triphosphate metabolic process GO:0009141 120 0.093
single organism biosynthetic process GO:0044711 206 0.093
positive regulation of macromolecule metabolic process GO:0010604 405 0.092
imaginal disc derived appendage development GO:0048737 399 0.090
organophosphate metabolic process GO:0019637 195 0.089
catabolic process GO:0009056 409 0.087
purine ribonucleotide catabolic process GO:0009154 109 0.086
appendage morphogenesis GO:0035107 397 0.086
autophagy GO:0006914 108 0.083
forebrain development GO:0030900 2 0.082
purine nucleoside triphosphate metabolic process GO:0009144 119 0.082
ribonucleotide metabolic process GO:0009259 145 0.082
organic substance catabolic process GO:1901575 308 0.082
digestive tract development GO:0048565 149 0.078
response to wounding GO:0009611 94 0.077
biological adhesion GO:0022610 138 0.077
mesoderm development GO:0007498 78 0.076
cellular response to chemical stimulus GO:0070887 199 0.076
organonitrogen compound metabolic process GO:1901564 318 0.075
maintenance of location GO:0051235 73 0.074
ribose phosphate metabolic process GO:0019693 145 0.073
nucleoside phosphate metabolic process GO:0006753 162 0.071
cation transmembrane transport GO:0098655 88 0.071
regulation of localization GO:0032879 275 0.069
regulation of growth GO:0040008 233 0.069
rna localization GO:0006403 115 0.069
regulation of neurogenesis GO:0050767 158 0.068
endomembrane system organization GO:0010256 119 0.067
glycosyl compound metabolic process GO:1901657 127 0.066
positive regulation of multicellular organismal process GO:0051240 143 0.065
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.065
negative regulation of nucleic acid templated transcription GO:1903507 240 0.065
membrane organization GO:0061024 112 0.064
actin cytoskeleton organization GO:0030036 206 0.063
response to external biotic stimulus GO:0043207 293 0.061
regulation of rna splicing GO:0043484 69 0.061
single organism catabolic process GO:0044712 228 0.059
ribonucleoside metabolic process GO:0009119 127 0.058
nuclear transport GO:0051169 72 0.058
protein localization GO:0008104 284 0.058
organelle assembly GO:0070925 198 0.057
nucleobase containing compound catabolic process GO:0034655 165 0.057
response to inorganic substance GO:0010035 44 0.056
response to metal ion GO:0010038 23 0.056
immune response GO:0006955 246 0.055
nuclear import GO:0051170 51 0.054
carbohydrate derivative metabolic process GO:1901135 217 0.053
cell proliferation GO:0008283 299 0.053
ion transmembrane transport GO:0034220 122 0.052
positive regulation of developmental process GO:0051094 143 0.051
urogenital system development GO:0001655 72 0.051
embryonic morphogenesis GO:0048598 206 0.051
positive regulation of cell death GO:0010942 69 0.050
cation homeostasis GO:0055080 51 0.050
negative regulation of transcription dna templated GO:0045892 237 0.050
regionalization GO:0003002 416 0.050
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
regulation of protein metabolic process GO:0051246 256 0.049
nucleoside metabolic process GO:0009116 127 0.049
homeostatic process GO:0042592 199 0.048
cytoplasmic transport GO:0016482 130 0.048
positive regulation of programmed cell death GO:0043068 62 0.047
rna splicing GO:0008380 83 0.047
central nervous system development GO:0007417 201 0.046
single organism membrane organization GO:0044802 93 0.045
regulation of cell proliferation GO:0042127 163 0.045
purine ribonucleoside catabolic process GO:0046130 112 0.044
cellular nitrogen compound catabolic process GO:0044270 165 0.043
aromatic compound catabolic process GO:0019439 166 0.043
regulation of programmed cell death GO:0043067 152 0.042
chemical homeostasis GO:0048878 92 0.042
ribonucleoside triphosphate metabolic process GO:0009199 119 0.041
gland development GO:0048732 191 0.040
retina development in camera type eye GO:0060041 4 0.040
purine nucleoside metabolic process GO:0042278 127 0.039
positive regulation of cell migration GO:0030335 2 0.039
tissue morphogenesis GO:0048729 297 0.038
regulation of developmental growth GO:0048638 174 0.038
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.038
cellular chemical homeostasis GO:0055082 40 0.036
camera type eye development GO:0043010 4 0.036
cell adhesion GO:0007155 136 0.036
wound healing GO:0042060 75 0.036
epidermis development GO:0008544 65 0.036
sensory perception of sound GO:0007605 56 0.036
cellular response to extracellular stimulus GO:0031668 64 0.035
cellular catabolic process GO:0044248 372 0.035
negative regulation of signal transduction GO:0009968 206 0.035
cellular homeostasis GO:0019725 80 0.034
transmembrane transport GO:0055085 139 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
nucleoside triphosphate catabolic process GO:0009143 108 0.033
regulation of cellular ph GO:0030641 7 0.033
appendage development GO:0048736 401 0.033
actin filament based process GO:0030029 220 0.032
gliogenesis GO:0042063 80 0.032
vesicle organization GO:0016050 44 0.032
heterocycle catabolic process GO:0046700 166 0.032
cellular cation homeostasis GO:0030003 38 0.031
negative regulation of rna metabolic process GO:0051253 251 0.031
apoptotic process GO:0006915 159 0.031
regulation of nervous system development GO:0051960 248 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
cation transport GO:0006812 110 0.030
dna packaging GO:0006323 91 0.030
neurological system process GO:0050877 358 0.030
proteolysis GO:0006508 192 0.030
positive regulation of signal transduction GO:0009967 223 0.030
intracellular ph reduction GO:0051452 7 0.030
histolysis GO:0007559 102 0.029
regulation of notch signaling pathway GO:0008593 100 0.029
regulation of intracellular transport GO:0032386 64 0.029
response to bacterium GO:0009617 198 0.029
protein targeting GO:0006605 64 0.029
phagocytosis GO:0006909 215 0.028
Fly
protein localization to nucleus GO:0034504 55 0.028
meiotic nuclear division GO:0007126 151 0.028
endosomal transport GO:0016197 44 0.028
chromatin assembly or disassembly GO:0006333 52 0.028
purine nucleotide catabolic process GO:0006195 109 0.027
positive regulation of immune system process GO:0002684 68 0.027
nucleoside catabolic process GO:0009164 112 0.027
response to biotic stimulus GO:0009607 294 0.027
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
guanosine containing compound metabolic process GO:1901068 74 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
negative regulation of neurogenesis GO:0050768 53 0.026
anterior posterior pattern specification GO:0009952 136 0.026
single organism behavior GO:0044708 391 0.026
protein maturation GO:0051604 71 0.026
purine containing compound catabolic process GO:0072523 112 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
cardiovascular system development GO:0072358 82 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
protein processing GO:0016485 68 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
syncytium formation GO:0006949 43 0.025
inorganic cation transmembrane transport GO:0098662 61 0.024
negative regulation of neuroblast proliferation GO:0007406 27 0.023
response to other organism GO:0051707 293 0.023
guanosine containing compound catabolic process GO:1901069 74 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
kidney development GO:0001822 3 0.023
gtp metabolic process GO:0046039 72 0.023
spindle organization GO:0007051 253 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
nucleocytoplasmic transport GO:0006913 72 0.023
nucleotide metabolic process GO:0009117 161 0.023
sensory perception GO:0007600 196 0.023
embryonic hindgut morphogenesis GO:0048619 48 0.023
protein import into nucleus GO:0006606 51 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
tissue death GO:0016271 102 0.022
negative regulation of cell development GO:0010721 62 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
regulation of cell development GO:0060284 215 0.022
regulation of molecular function GO:0065009 217 0.022
defense response GO:0006952 300 0.022
small molecule metabolic process GO:0044281 305 0.022
protein import GO:0017038 55 0.021
protein targeting to nucleus GO:0044744 51 0.021
cellular ion homeostasis GO:0006873 39 0.021
tube morphogenesis GO:0035239 191 0.021
wing disc morphogenesis GO:0007472 344 0.021
male gamete generation GO:0048232 201 0.021
brain development GO:0007420 120 0.021
mrna processing GO:0006397 104 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
learning GO:0007612 75 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
glycosyl compound catabolic process GO:1901658 112 0.020
organophosphate catabolic process GO:0046434 112 0.020
regulation of apoptotic process GO:0042981 130 0.020
negative regulation of stem cell proliferation GO:2000647 30 0.020
regulation of neuroblast proliferation GO:1902692 34 0.020
g protein coupled receptor signaling pathway GO:0007186 136 0.020
negative regulation of signaling GO:0023057 219 0.020
establishment of protein localization to organelle GO:0072594 62 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
response to organic substance GO:0010033 284 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
phosphorylation GO:0016310 294 0.020
head development GO:0060322 135 0.020
positive regulation of catabolic process GO:0009896 105 0.020
necrotic cell death GO:0070265 1 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
morphogenesis of a branching structure GO:0001763 45 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
eye development GO:0001654 323 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
regulation of peptidase activity GO:0052547 39 0.019
mrna metabolic process GO:0016071 124 0.019
circulatory system development GO:0072359 82 0.019
larval midgut histolysis GO:0035069 22 0.018
lipid biosynthetic process GO:0008610 46 0.018
nucleoside phosphate catabolic process GO:1901292 110 0.018
organophosphate biosynthetic process GO:0090407 46 0.018
regulation of catabolic process GO:0009894 170 0.018
regulation of response to stress GO:0080134 200 0.018
salivary gland histolysis GO:0035070 88 0.018
defense response to other organism GO:0098542 225 0.018
digestive system development GO:0055123 149 0.018
positive regulation of gene expression GO:0010628 290 0.018
nucleobase containing compound transport GO:0015931 56 0.018
gtp catabolic process GO:0006184 72 0.018
body morphogenesis GO:0010171 2 0.018
regulation of hydrolase activity GO:0051336 97 0.018
cellular response to organic substance GO:0071310 132 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
regulation of catalytic activity GO:0050790 185 0.017
renal system development GO:0072001 72 0.017
embryonic development via the syncytial blastoderm GO:0001700 148 0.017
regulation of transport GO:0051049 181 0.016
negative regulation of nervous system development GO:0051961 92 0.016
dendrite morphogenesis GO:0048813 199 0.016
sensory organ morphogenesis GO:0090596 260 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
larval development GO:0002164 104 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
protein localization to organelle GO:0033365 82 0.016
negative regulation of neural precursor cell proliferation GO:2000178 27 0.016
cellular respiration GO:0045333 26 0.016
atp metabolic process GO:0046034 49 0.016
positive regulation of cell motility GO:2000147 3 0.016
syncytium formation by plasma membrane fusion GO:0000768 43 0.016
developmental maturation GO:0021700 172 0.016
regulation of mrna metabolic process GO:1903311 72 0.015
anion transport GO:0006820 41 0.015
inorganic ion transmembrane transport GO:0098660 73 0.015
cell migration GO:0016477 238 0.015
cell motility GO:0048870 251 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
muscle attachment GO:0016203 36 0.015
glial cell differentiation GO:0010001 35 0.015
regeneration GO:0031099 16 0.015
mitotic spindle organization GO:0007052 220 0.015
translation GO:0006412 69 0.015
mapk cascade GO:0000165 107 0.015
segmentation GO:0035282 207 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
carbohydrate metabolic process GO:0005975 82 0.015
dendrite development GO:0016358 204 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
anterior posterior axis specification GO:0009948 109 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
organic acid metabolic process GO:0006082 103 0.014
tube development GO:0035295 244 0.014
muscle cell differentiation GO:0042692 103 0.014
ribonucleoside biosynthetic process GO:0042455 3 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
purine nucleoside monophosphate biosynthetic process GO:0009127 3 0.014
digestive tract morphogenesis GO:0048546 127 0.014
positive regulation of molecular function GO:0044093 136 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of response to wounding GO:1903034 19 0.014
sterol homeostasis GO:0055092 4 0.014
malpighian tubule morphogenesis GO:0007443 44 0.014
ion homeostasis GO:0050801 55 0.014
positive regulation of signaling GO:0023056 243 0.014
protein dna complex assembly GO:0065004 63 0.013
response to hexose GO:0009746 3 0.013
regulation of cell cycle GO:0051726 291 0.013
nitrogen compound transport GO:0071705 85 0.013
cellular response to nutrient levels GO:0031669 62 0.013
axis specification GO:0009798 167 0.013
golgi organization GO:0007030 66 0.013
nucleotide catabolic process GO:0009166 109 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
epidermal cell differentiation GO:0009913 51 0.013
regulation of neuron differentiation GO:0045664 103 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
rna transport GO:0050658 46 0.013
cellular response to external stimulus GO:0071496 66 0.013
meiotic cell cycle GO:0051321 171 0.013
establishment of planar polarity GO:0001736 87 0.013
regulation of cellular localization GO:0060341 136 0.012
regulation of protein localization GO:0032880 76 0.012
regulation of tube diameter GO:0035296 14 0.012
rna processing GO:0006396 147 0.012
regulation of endopeptidase activity GO:0052548 36 0.012
regulation of neuron projection development GO:0010975 69 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
regulation of ph GO:0006885 7 0.012
response to copper ion GO:0046688 4 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
regulation of glial cell differentiation GO:0045685 1 0.012
embryonic axis specification GO:0000578 107 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
cell maturation GO:0048469 144 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of mrna processing GO:0050684 71 0.012
eye pigment granule organization GO:0008057 12 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
stem cell differentiation GO:0048863 117 0.012
developmental programmed cell death GO:0010623 138 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
regulation of body fluid levels GO:0050878 14 0.011
copper ion homeostasis GO:0055070 7 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
pigmentation GO:0043473 75 0.011
multi organism behavior GO:0051705 175 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
positive regulation of cell communication GO:0010647 250 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
regulation of phosphorylation GO:0042325 147 0.011
protein kinase b signaling GO:0043491 1 0.011
neuron recognition GO:0008038 101 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
regulation of response to external stimulus GO:0032101 115 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
response to calcium ion GO:0051592 1 0.011
ameboidal type cell migration GO:0001667 151 0.011
chromosome segregation GO:0007059 157 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
ribonucleoside monophosphate biosynthetic process GO:0009156 3 0.011
macromolecular complex assembly GO:0065003 256 0.010
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
single organism nuclear import GO:1902593 51 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
notch signaling pathway GO:0007219 120 0.010
vesicle fusion GO:0006906 19 0.010
intracellular signal transduction GO:0035556 300 0.010
positive regulation of cell development GO:0010720 61 0.010

Vha16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
urinary system disease DOID:18 0 0.022
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
disease of metabolism DOID:0014667 0 0.011