Drosophila melanogaster

23 known processes

ia2 (Dmel_CG31795)

CG31795 gene product from transcript CG31795-RD

(Aliases: CG31795,Dmel\CG31795,R-PTPX/1A2,CG11344,CG4355,anon-WO0153538.69)

ia2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.378
chitin based cuticle sclerotization GO:0007593 19 0.374
sensory perception of chemical stimulus GO:0007606 116 0.173
regulation of chitin based cuticle tanning GO:0007564 14 0.170
molting cycle process GO:0022404 29 0.164
catechol containing compound biosynthetic process GO:0009713 3 0.159
regulation of multicellular organismal development GO:2000026 414 0.158
molting cycle chitin based cuticle GO:0007591 56 0.153
amine metabolic process GO:0009308 12 0.123
single organism behavior GO:0044708 391 0.119
response to abiotic stimulus GO:0009628 341 0.108
catecholamine biosynthetic process GO:0042423 3 0.100
adult behavior GO:0030534 137 0.091
cell maturation GO:0048469 144 0.091
regulation of developmental pigmentation GO:0048070 24 0.086
response to insecticide GO:0017085 14 0.085
response to extracellular stimulus GO:0009991 116 0.084
adult locomotory behavior GO:0008344 76 0.082
phenol containing compound metabolic process GO:0018958 57 0.079
endocytosis GO:0006897 310 0.078
organonitrogen compound metabolic process GO:1901564 318 0.076
small molecule metabolic process GO:0044281 305 0.072
establishment of localization in cell GO:0051649 402 0.071
developmental maturation GO:0021700 172 0.070
adult chitin containing cuticle pigmentation GO:0048085 16 0.069
regulation of cellular amine metabolic process GO:0033238 3 0.064
regulation of reproductive process GO:2000241 54 0.064
cellular amine metabolic process GO:0044106 12 0.063
vesicle mediated transport GO:0016192 381 0.062
locomotory behavior GO:0007626 176 0.060
axon development GO:0061564 297 0.059
response to oxygen containing compound GO:1901700 200 0.057
negative regulation of cellular metabolic process GO:0031324 382 0.055
molting cycle GO:0042303 56 0.054
defense response GO:0006952 300 0.053
tube development GO:0035295 244 0.053
phagocytosis GO:0006909 215 0.051
cognition GO:0050890 141 0.050
regulation of cuticle pigmentation GO:0048079 16 0.050
telencephalon development GO:0021537 2 0.049
neurological system process GO:0050877 358 0.049
organelle localization GO:0051640 148 0.048
organelle fission GO:0048285 340 0.048
cellular protein localization GO:0034613 160 0.047
forebrain development GO:0030900 2 0.047
positive regulation of signaling GO:0023056 243 0.047
spermatogenesis GO:0007283 200 0.046
cellular macromolecule localization GO:0070727 220 0.045
response to external biotic stimulus GO:0043207 293 0.045
catabolic process GO:0009056 409 0.044
negative regulation of gene expression GO:0010629 387 0.043
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
cellular catabolic process GO:0044248 372 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.042
toxin metabolic process GO:0009404 2 0.041
kidney development GO:0001822 3 0.041
regulation of localization GO:0032879 275 0.040
learning GO:0007612 75 0.040
establishment of planar polarity GO:0001736 87 0.040
cell division GO:0051301 248 0.037
cell migration GO:0016477 238 0.037
establishment of tissue polarity GO:0007164 87 0.037
regulation of defense response GO:0031347 102 0.036
taxis GO:0042330 304 0.036
axonogenesis GO:0007409 290 0.035
organic substance catabolic process GO:1901575 308 0.034
catechol containing compound metabolic process GO:0009712 10 0.034
organic hydroxy compound biosynthetic process GO:1901617 21 0.034
learning or memory GO:0007611 141 0.034
innate immune response GO:0045087 144 0.033
organic substance transport GO:0071702 257 0.033
muscle organ development GO:0007517 127 0.033
cardiovascular system development GO:0072358 82 0.033
regulation of epithelial cell proliferation GO:0050678 4 0.032
muscle tissue development GO:0060537 30 0.032
body morphogenesis GO:0010171 2 0.032
cellular response to chemical stimulus GO:0070887 199 0.031
carboxylic acid metabolic process GO:0019752 92 0.031
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.031
tissue morphogenesis GO:0048729 297 0.031
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
positive regulation of gene expression GO:0010628 290 0.030
single organism biosynthetic process GO:0044711 206 0.030
appendage morphogenesis GO:0035107 397 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
regulation of cell cycle GO:0051726 291 0.029
cuticle development GO:0042335 86 0.029
axon guidance GO:0007411 233 0.029
cuticle pigmentation GO:0048067 22 0.029
intracellular signal transduction GO:0035556 300 0.029
nucleobase containing compound catabolic process GO:0034655 165 0.029
protein modification process GO:0036211 438 0.028
sensory organ morphogenesis GO:0090596 260 0.028
organic acid metabolic process GO:0006082 103 0.027
regulation of molecular function GO:0065009 217 0.027
regulation of proteolysis GO:0030162 87 0.027
phosphorylation GO:0016310 294 0.026
olfactory learning GO:0008355 56 0.026
muscle structure development GO:0061061 224 0.026
oxoacid metabolic process GO:0043436 103 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
circulatory system development GO:0072359 82 0.026
meiotic nuclear division GO:0007126 151 0.025
immune response GO:0006955 246 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
chemotaxis GO:0006935 249 0.025
intracellular transport GO:0046907 228 0.025
cellular response to extracellular stimulus GO:0031668 64 0.025
nucleotide metabolic process GO:0009117 161 0.024
cellular protein modification process GO:0006464 438 0.024
response to nutrient levels GO:0031667 114 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
localization of cell GO:0051674 257 0.024
regulation of hydrolase activity GO:0051336 97 0.024
meiotic cell cycle GO:0051321 171 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
protein localization GO:0008104 284 0.023
cellular response to oxidative stress GO:0034599 28 0.023
positive regulation of signal transduction GO:0009967 223 0.023
cellular response to organic substance GO:0071310 132 0.023
sensory perception GO:0007600 196 0.023
purine containing compound metabolic process GO:0072521 155 0.023
organophosphate metabolic process GO:0019637 195 0.022
regulation of cysteine type endopeptidase activity GO:2000116 27 0.022
establishment of organelle localization GO:0051656 122 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
response to peptide hormone GO:0043434 29 0.022
central nervous system development GO:0007417 201 0.022
immune response activating signal transduction GO:0002757 2 0.022
tube morphogenesis GO:0035239 191 0.022
macromolecule catabolic process GO:0009057 161 0.022
positive regulation of molecular function GO:0044093 136 0.022
response to organic substance GO:0010033 284 0.022
long term memory GO:0007616 62 0.021
neuron maturation GO:0042551 31 0.021
response to decreased oxygen levels GO:0036293 58 0.021
chromosome segregation GO:0007059 157 0.021
single organism intracellular transport GO:1902582 207 0.021
epithelial cell differentiation GO:0030855 322 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
regulation of establishment of planar polarity GO:0090175 22 0.021
segmentation GO:0035282 207 0.021
cellular homeostasis GO:0019725 80 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
positive regulation of cell communication GO:0010647 250 0.020
regulation of apoptotic process GO:0042981 130 0.020
skeletal muscle organ development GO:0060538 48 0.020
cellular response to light stimulus GO:0071482 37 0.020
defense response to other organism GO:0098542 225 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
nuclear division GO:0000280 332 0.020
response to oxidative stress GO:0006979 86 0.020
response to hypoxia GO:0001666 53 0.020
regulation of intracellular signal transduction GO:1902531 236 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
cellular response to external stimulus GO:0071496 66 0.019
cell adhesion GO:0007155 136 0.019
heterocycle catabolic process GO:0046700 166 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
dopamine metabolic process GO:0042417 7 0.019
morphogenesis of a polarized epithelium GO:0001738 93 0.019
regulation of programmed cell death GO:0043067 152 0.019
indole containing compound biosynthetic process GO:0042435 4 0.018
cell proliferation GO:0008283 299 0.018
phenol containing compound biosynthetic process GO:0046189 6 0.018
regulation of immune system process GO:0002682 176 0.018
mapk cascade GO:0000165 107 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
positive regulation of cell death GO:0010942 69 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
male meiosis GO:0007140 52 0.018
pigmentation GO:0043473 75 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
glycosyl compound metabolic process GO:1901657 127 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
striated muscle tissue development GO:0014706 27 0.017
protein maturation GO:0051604 71 0.017
eye development GO:0001654 323 0.017
growth GO:0040007 359 0.017
developmental pigmentation GO:0048066 68 0.017
mitotic nuclear division GO:0007067 213 0.017
cation transmembrane transport GO:0098655 88 0.017
developmental growth GO:0048589 280 0.017
lipid metabolic process GO:0006629 121 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
aromatic compound catabolic process GO:0019439 166 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
dopamine biosynthetic process GO:0042416 3 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
ovarian follicle cell development GO:0030707 248 0.016
secretion GO:0046903 109 0.016
single organism cellular localization GO:1902580 180 0.016
establishment of synaptic vesicle localization GO:0097480 50 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
rhythmic process GO:0048511 106 0.016
protein catabolic process GO:0030163 101 0.016
camera type eye development GO:0043010 4 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
proteolysis GO:0006508 192 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
mitotic spindle organization GO:0007052 220 0.015
regulation of transport GO:0051049 181 0.015
head development GO:0060322 135 0.015
ovulation GO:0030728 4 0.015
digestive tract morphogenesis GO:0048546 127 0.015
response to endogenous stimulus GO:0009719 119 0.015
cellular ion homeostasis GO:0006873 39 0.015
aging GO:0007568 143 0.015
chromosome condensation GO:0030261 41 0.015
humoral immune response GO:0006959 117 0.015
cell cycle phase transition GO:0044770 140 0.015
connective tissue development GO:0061448 3 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
metal ion homeostasis GO:0055065 44 0.015
ribonucleotide metabolic process GO:0009259 145 0.014
death GO:0016265 284 0.014
regulation of catalytic activity GO:0050790 185 0.014
response to temperature stimulus GO:0009266 106 0.014
ameboidal type cell migration GO:0001667 151 0.014
ion transmembrane transport GO:0034220 122 0.014
multi organism behavior GO:0051705 175 0.014
positive regulation of cell cycle GO:0045787 43 0.014
immune system process GO:0002376 347 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
anatomical structure homeostasis GO:0060249 97 0.014
response to oxygen levels GO:0070482 59 0.014
synapse assembly GO:0007416 143 0.014
regionalization GO:0003002 416 0.014
response to organonitrogen compound GO:0010243 75 0.014
single organism catabolic process GO:0044712 228 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
macromolecular complex assembly GO:0065003 256 0.014
associative learning GO:0008306 65 0.014
dna metabolic process GO:0006259 227 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
establishment of protein localization GO:0045184 163 0.013
cellular ketone metabolic process GO:0042180 24 0.013
regulation of anatomical structure size GO:0090066 163 0.013
response to wounding GO:0009611 94 0.013
response to alcohol GO:0097305 95 0.013
regulation of protein metabolic process GO:0051246 256 0.013
epithelium migration GO:0090132 148 0.013
negative regulation of cell death GO:0060548 81 0.013
cellular lipid metabolic process GO:0044255 83 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
purine containing compound catabolic process GO:0072523 112 0.013
actin filament based process GO:0030029 220 0.013
ion homeostasis GO:0050801 55 0.013
multicellular organismal aging GO:0010259 140 0.013
synaptic vesicle localization GO:0097479 53 0.013
embryonic morphogenesis GO:0048598 206 0.013
lipid localization GO:0010876 54 0.013
pattern recognition receptor signaling pathway GO:0002221 2 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
neuron recognition GO:0008038 101 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
chitin based cuticle development GO:0040003 49 0.013
regulation of establishment of protein localization GO:0070201 61 0.012
positive regulation of catabolic process GO:0009896 105 0.012
vesicle localization GO:0051648 55 0.012
organelle assembly GO:0070925 198 0.012
response to inorganic substance GO:0010035 44 0.012
lateral inhibition GO:0046331 206 0.012
vitamin metabolic process GO:0006766 2 0.012
detection of abiotic stimulus GO:0009582 66 0.012
brain development GO:0007420 120 0.012
response to hexose GO:0009746 3 0.012
olfactory behavior GO:0042048 97 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
mitochondrion organization GO:0007005 65 0.012
chromosome organization GO:0051276 360 0.012
divalent inorganic cation transport GO:0072511 30 0.012
regulation of multi organism process GO:0043900 131 0.012
cytoplasmic transport GO:0016482 130 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
tissue death GO:0016271 102 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
negative regulation of proteolysis GO:0045861 31 0.012
wound healing GO:0042060 75 0.012
nephron development GO:0072006 3 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
regulation of synapse organization GO:0050807 110 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
cellular response to radiation GO:0071478 52 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
cellular response to growth factor stimulus GO:0071363 30 0.012
wnt signaling pathway GO:0016055 98 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
gastrulation GO:0007369 70 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
sensory perception of smell GO:0007608 80 0.011
regulation of response to stress GO:0080134 200 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
response to starvation GO:0042594 97 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
response to lipopolysaccharide GO:0032496 4 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cellular localization GO:0060341 136 0.011
protein complex biogenesis GO:0070271 201 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
mesoderm development GO:0007498 78 0.011
response to light stimulus GO:0009416 124 0.011
female meiotic division GO:0007143 70 0.011
eye morphogenesis GO:0048592 260 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
ion transport GO:0006811 145 0.011
metal ion transport GO:0030001 74 0.011
protein processing GO:0016485 68 0.011
organophosphate biosynthetic process GO:0090407 46 0.011
organophosphate catabolic process GO:0046434 112 0.011
maintenance of location GO:0051235 73 0.011
response to glucose GO:0009749 2 0.011
gland morphogenesis GO:0022612 145 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
homeostatic process GO:0042592 199 0.011
dopamine biosynthetic process from tyrosine GO:0006585 1 0.011
cellular response to starvation GO:0009267 61 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of nervous system development GO:0051960 248 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
protein transport GO:0015031 155 0.010
dna conformation change GO:0071103 105 0.010
nephron epithelium development GO:0072009 3 0.010
detection of stimulus GO:0051606 156 0.010
negative regulation of catalytic activity GO:0043086 42 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
multi multicellular organism process GO:0044706 123 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
positive regulation of defense response GO:0031349 59 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
acylglycerol biosynthetic process GO:0046463 2 0.010
chromatin organization GO:0006325 207 0.010
reflex GO:0060004 6 0.010
response to hormone GO:0009725 45 0.010
response to growth factor GO:0070848 31 0.010
intracellular protein transport GO:0006886 104 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
epithelial cell development GO:0002064 274 0.010
nucleoside metabolic process GO:0009116 127 0.010
actin filament organization GO:0007015 126 0.010
regulation of protein localization GO:0032880 76 0.010
regulation of cell proliferation GO:0042127 163 0.010
organic hydroxy compound metabolic process GO:1901615 83 0.010
protein phosphorylation GO:0006468 169 0.010
apoptotic process GO:0006915 159 0.010
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.010
salt aversion GO:0035199 3 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010

ia2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cardiovascular system disease DOID:1287 0 0.037
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
musculoskeletal system disease DOID:17 0 0.021
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.011