Drosophila melanogaster

51 known processes

BobA (Dmel_CG12487)

Brother of Bearded A

(Aliases: Dmel\CG12487,Bob,bobA,CG12487,Bob-A)

BobA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.375
neuron fate determination GO:0048664 1 0.251
formation of anatomical boundary GO:0048859 37 0.241
cell fate determination involved in pattern specification GO:0060582 19 0.237
sensory organ precursor cell fate determination GO:0016360 19 0.231
organ formation GO:0048645 39 0.109
tyrosine phosphorylation of stat protein GO:0007260 1 0.105
sensory organ boundary specification GO:0008052 22 0.104
r7 cell differentiation GO:0045466 43 0.100
hair cell differentiation GO:0035315 47 0.096
formation of organ boundary GO:0010160 30 0.095
establishment of planar polarity GO:0001736 87 0.088
negative regulation of response to stimulus GO:0048585 258 0.086
immune system process GO:0002376 347 0.073
camera type eye development GO:0043010 4 0.072
compound eye morphogenesis GO:0001745 249 0.070
regulation of cell morphogenesis GO:0022604 163 0.063
negative regulation of notch signaling pathway GO:0045746 41 0.063
neurological system process GO:0050877 358 0.062
r1 r6 cell differentiation GO:0048052 4 0.061
positive regulation of response to stimulus GO:0048584 323 0.060
larval behavior GO:0030537 42 0.059
single organism behavior GO:0044708 391 0.059
locomotory behavior GO:0007626 176 0.057
establishment of tissue polarity GO:0007164 87 0.056
nephron epithelium morphogenesis GO:0072088 3 0.056
stem cell maintenance GO:0019827 67 0.055
regulation of notch signaling pathway GO:0008593 100 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.055
axon ensheathment in central nervous system GO:0032291 3 0.053
adult behavior GO:0030534 137 0.053
connective tissue development GO:0061448 3 0.052
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.052
chaeta development GO:0022416 97 0.052
small molecule metabolic process GO:0044281 305 0.050
endocytosis GO:0006897 310 0.050
regulation of glial cell differentiation GO:0045685 1 0.050
larval locomotory behavior GO:0008345 27 0.049
organelle fission GO:0048285 340 0.048
negative regulation of gene expression GO:0010629 387 0.048
epidermal cell differentiation GO:0009913 51 0.047
positive regulation of bmp signaling pathway GO:0030513 5 0.047
eye morphogenesis GO:0048592 260 0.046
compound eye development GO:0048749 307 0.046
open tracheal system development GO:0007424 204 0.046
kidney development GO:0001822 3 0.046
stem cell fate specification GO:0048866 2 0.045
startle response GO:0001964 16 0.045
eye development GO:0001654 323 0.045
forebrain development GO:0030900 2 0.045
tissue morphogenesis GO:0048729 297 0.044
regulation of stem cell proliferation GO:0072091 40 0.044
wing disc pattern formation GO:0035222 66 0.041
negative regulation of signal transduction GO:0009968 206 0.041
cell fate determination GO:0001709 91 0.041
mitotic nuclear division GO:0007067 213 0.040
regulation of gene expression epigenetic GO:0040029 128 0.040
biological adhesion GO:0022610 138 0.038
intracellular signal transduction GO:0035556 300 0.038
neuron projection guidance GO:0097485 241 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.036
positive regulation of cell communication GO:0010647 250 0.036
body morphogenesis GO:0010171 2 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
cell division GO:0051301 248 0.035
sensory organ morphogenesis GO:0090596 260 0.035
compound eye photoreceptor cell differentiation GO:0001751 140 0.035
segmentation GO:0035282 207 0.035
glial cell fate commitment GO:0021781 3 0.035
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
appendage morphogenesis GO:0035107 397 0.034
regulation of response to stress GO:0080134 200 0.034
notch signaling pathway GO:0007219 120 0.033
nephron development GO:0072006 3 0.033
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.032
epithelial cell development GO:0002064 274 0.032
actin cytoskeleton organization GO:0030036 206 0.032
epidermis development GO:0008544 65 0.032
axonogenesis GO:0007409 290 0.032
hematopoietic or lymphoid organ development GO:0048534 57 0.032
positive regulation of rna biosynthetic process GO:1902680 266 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
eye photoreceptor cell differentiation GO:0001754 145 0.031
defense response GO:0006952 300 0.030
nephron tubule development GO:0072080 3 0.030
negative regulation of signaling GO:0023057 219 0.029
positive regulation of signal transduction GO:0009967 223 0.029
positive regulation of cell cycle process GO:0090068 28 0.029
dosage compensation GO:0007549 16 0.029
positive regulation of developmental process GO:0051094 143 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
anterior posterior pattern specification GO:0009952 136 0.028
nuclear division GO:0000280 332 0.028
regulation of immune system process GO:0002682 176 0.027
somatic sex determination GO:0018993 2 0.027
appendage development GO:0048736 401 0.027
regulation of membrane potential GO:0042391 35 0.027
smoothened signaling pathway GO:0007224 49 0.027
nephron tubule formation GO:0072079 3 0.027
multi organism reproductive behavior GO:0044705 121 0.026
protein complex biogenesis GO:0070271 201 0.026
nephron tubule morphogenesis GO:0072078 3 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.026
detection of stimulus GO:0051606 156 0.026
positive regulation of signaling GO:0023056 243 0.026
kidney epithelium development GO:0072073 3 0.026
cellular component assembly involved in morphogenesis GO:0010927 151 0.026
locomotor rhythm GO:0045475 56 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
imaginal disc pattern formation GO:0007447 91 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
vesicle mediated transport GO:0016192 381 0.026
sex determination establishment of x a ratio GO:0007540 1 0.026
cellular ketone metabolic process GO:0042180 24 0.025
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
exocrine system development GO:0035272 162 0.025
multi organism behavior GO:0051705 175 0.025
epithelial cell differentiation GO:0030855 322 0.025
morphogenesis of an epithelium GO:0002009 276 0.025
dorsal ventral pattern formation GO:0009953 133 0.025
multicellular organismal signaling GO:0035637 12 0.024
cranial nerve development GO:0021545 1 0.024
protein complex assembly GO:0006461 200 0.024
protein modification process GO:0036211 438 0.024
positive regulation of molecular function GO:0044093 136 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
cell fate commitment involved in pattern specification GO:0060581 31 0.024
gastrulation involving germ band extension GO:0010004 36 0.024
adult locomotory behavior GO:0008344 76 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
spinal cord patterning GO:0021511 1 0.023
neuronal action potential GO:0019228 10 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
courtship behavior GO:0007619 68 0.023
regulation of neuroblast proliferation GO:1902692 34 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
neuroblast fate specification GO:0014018 2 0.023
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.023
stem cell fate commitment GO:0048865 25 0.022
organic substance catabolic process GO:1901575 308 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
nephron epithelium development GO:0072009 3 0.022
neural retina development GO:0003407 4 0.022
catabolic process GO:0009056 409 0.022
negative regulation of immune system process GO:0002683 50 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
regulation of molecular function GO:0065009 217 0.021
hemopoiesis GO:0030097 46 0.021
segment specification GO:0007379 33 0.021
centrosome duplication GO:0051298 121 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
regulation of nervous system development GO:0051960 248 0.020
cellular protein modification process GO:0006464 438 0.020
skin development GO:0043588 65 0.020
neuromuscular process GO:0050905 21 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.020
transmission of nerve impulse GO:0019226 12 0.020
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.020
regulation of timing of cell differentiation GO:0048505 1 0.020
regulation of phosphate metabolic process GO:0019220 210 0.019
rhythmic process GO:0048511 106 0.019
homeostatic process GO:0042592 199 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
negative regulation of biosynthetic process GO:0009890 277 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
regulation of catalytic activity GO:0050790 185 0.018
ovarian follicle cell development GO:0030707 248 0.018
neuronal stem cell maintenance GO:0097150 4 0.018
chaeta morphogenesis GO:0008407 42 0.018
gland morphogenesis GO:0022612 145 0.018
organelle assembly GO:0070925 198 0.018
wing disc dorsal ventral pattern formation GO:0048190 47 0.018
developmental maturation GO:0021700 172 0.018
macromolecular complex assembly GO:0065003 256 0.018
regulation of cell development GO:0060284 215 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
response to abiotic stimulus GO:0009628 341 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
positive regulation of catalytic activity GO:0043085 118 0.017
embryonic organ development GO:0048568 50 0.017
glial cell differentiation GO:0010001 35 0.017
organic acid metabolic process GO:0006082 103 0.017
stem cell differentiation GO:0048863 117 0.017
eggshell formation GO:0030703 105 0.017
mating behavior GO:0007617 106 0.017
wing disc morphogenesis GO:0007472 344 0.017
nephron morphogenesis GO:0072028 3 0.017
macromolecule catabolic process GO:0009057 161 0.017
actin filament based process GO:0030029 220 0.017
cell proliferation GO:0008283 299 0.017
cellular catabolic process GO:0044248 372 0.017
phosphorylation GO:0016310 294 0.017
developmental programmed cell death GO:0010623 138 0.017
salivary gland development GO:0007431 162 0.017
phagocytosis GO:0006909 215 0.017
cell death GO:0008219 279 0.017
salivary gland morphogenesis GO:0007435 145 0.017
actin filament organization GO:0007015 126 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.017
regulation of cell cycle process GO:0010564 181 0.017
regulation of mitotic cell cycle GO:0007346 190 0.016
histolysis GO:0007559 102 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
dendrite morphogenesis GO:0048813 199 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
regulation of cell differentiation GO:0045595 302 0.016
renal system development GO:0072001 72 0.016
tube development GO:0035295 244 0.016
positive regulation of gene expression GO:0010628 290 0.016
positive regulation of notch signaling pathway GO:0045747 34 0.016
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
detection of stimulus involved in sensory perception GO:0050906 92 0.016
positive regulation of phosphorylation GO:0042327 87 0.015
stem cell proliferation GO:0072089 88 0.015
gland development GO:0048732 191 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
rhythmic behavior GO:0007622 76 0.015
telencephalon development GO:0021537 2 0.015
humoral immune response GO:0006959 117 0.015
axon development GO:0061564 297 0.015
morphogenesis of a polarized epithelium GO:0001738 93 0.015
dendrite development GO:0016358 204 0.015
spinal cord dorsal ventral patterning GO:0021513 1 0.015
negative regulation of cell communication GO:0010648 223 0.015
digestive system development GO:0055123 149 0.015
regulation of cell proliferation GO:0042127 163 0.015
cuticle development GO:0042335 86 0.015
cell fate specification GO:0001708 71 0.015
gene silencing GO:0016458 138 0.014
protein phosphorylation GO:0006468 169 0.014
regulation of organelle organization GO:0033043 196 0.014
response to hypoxia GO:0001666 53 0.014
primary sex determination soma GO:0007539 2 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
autophagic cell death GO:0048102 83 0.014
centrosome organization GO:0051297 163 0.014
regulation of phosphorylation GO:0042325 147 0.014
response to organic substance GO:0010033 284 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
regulation of cell death GO:0010941 173 0.014
action potential GO:0001508 13 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
death GO:0016265 284 0.014
camera type eye morphogenesis GO:0048593 2 0.014
response to oxygen levels GO:0070482 59 0.014
cytoskeleton dependent cytokinesis GO:0061640 81 0.014
tube morphogenesis GO:0035239 191 0.014
glycosyl compound catabolic process GO:1901658 112 0.013
reproductive behavior GO:0019098 122 0.013
chorion containing eggshell formation GO:0007304 105 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
multi multicellular organism process GO:0044706 123 0.013
regulation of bmp signaling pathway GO:0030510 23 0.013
nucleotide metabolic process GO:0009117 161 0.013
kidney morphogenesis GO:0060993 3 0.013
brain morphogenesis GO:0048854 16 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
glial cell development GO:0021782 27 0.013
limb morphogenesis GO:0035108 1 0.013
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.013
response to bacterium GO:0009617 198 0.013
regulation of protein metabolic process GO:0051246 256 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
organelle localization GO:0051640 148 0.013
proteolysis GO:0006508 192 0.013
regulation of programmed cell death GO:0043067 152 0.013
gliogenesis GO:0042063 80 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cellular amine metabolic process GO:0044106 12 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
digestive tract morphogenesis GO:0048546 127 0.012
regulation of response to dna damage stimulus GO:2001020 23 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
compound eye photoreceptor fate commitment GO:0001752 36 0.012
embryonic morphogenesis GO:0048598 206 0.012
developmental cell growth GO:0048588 52 0.012
regulation of mitosis GO:0007088 56 0.012
taxis GO:0042330 304 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
mitotic spindle organization GO:0007052 220 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
regulation of cellular component size GO:0032535 98 0.012
sensory perception of pain GO:0019233 4 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
positive regulation of protein kinase activity GO:0045860 25 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
eye photoreceptor cell fate commitment GO:0042706 37 0.012
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.012
positive regulation of nervous system development GO:0051962 69 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
protein catabolic process GO:0030163 101 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
dna metabolic process GO:0006259 227 0.011
positive regulation of cell development GO:0010720 61 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
regulation of embryonic development GO:0045995 68 0.011
tube formation GO:0035148 21 0.011
response to hexose GO:0009746 3 0.011
regulation of cell projection organization GO:0031344 92 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of cell division GO:0051302 72 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
response to decreased oxygen levels GO:0036293 58 0.011
regulation of anatomical structure size GO:0090066 163 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
salivary gland histolysis GO:0035070 88 0.011
regulation of multi organism process GO:0043900 131 0.011
establishment of organelle localization GO:0051656 122 0.011
organic substance transport GO:0071702 257 0.011
regulation of localization GO:0032879 275 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
response to biotic stimulus GO:0009607 294 0.011
microtubule organizing center organization GO:0031023 168 0.011
regulation of gene silencing GO:0060968 63 0.011
ion transport GO:0006811 145 0.010
regulation of apoptotic process GO:0042981 130 0.010
antimicrobial humoral response GO:0019730 99 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
regulation of transport GO:0051049 181 0.010
chromatin silencing GO:0006342 76 0.010
mesoderm development GO:0007498 78 0.010
male mating behavior GO:0060179 70 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
actin filament based movement GO:0030048 26 0.010
positive regulation of catabolic process GO:0009896 105 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
limb development GO:0060173 1 0.010
regulation of cellular response to stress GO:0080135 89 0.010
immune system development GO:0002520 57 0.010
positive regulation of cell cycle GO:0045787 43 0.010
respiratory system development GO:0060541 213 0.010
localization of cell GO:0051674 257 0.010
response to other organism GO:0051707 293 0.010
purine nucleoside catabolic process GO:0006152 112 0.010

BobA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
musculoskeletal system disease DOID:17 0 0.037
bone development disease DOID:0080006 0 0.033
bone disease DOID:0080001 0 0.033
connective tissue disease DOID:65 0 0.033
dysostosis DOID:1934 0 0.028
spondylocostal dysostosis DOID:0050568 0 0.026
urinary system disease DOID:18 0 0.019
nervous system disease DOID:863 0 0.013