Drosophila melanogaster

34 known processes

wkd (Dmel_CG5344)

whacked

(Aliases: CG5344,cg5344,Dmel\CG5344)

wkd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trachea morphogenesis GO:0060439 22 0.982
trachea development GO:0060438 29 0.951
branching involved in open tracheal system development GO:0060446 45 0.892
terminal branching open tracheal system GO:0007430 17 0.858
open tracheal system development GO:0007424 204 0.778
respiratory system development GO:0060541 213 0.708
tissue morphogenesis GO:0048729 297 0.558
branching morphogenesis of an epithelial tube GO:0048754 45 0.486
tube morphogenesis GO:0035239 191 0.410
morphogenesis of an epithelium GO:0002009 276 0.403
tube development GO:0035295 244 0.373
morphogenesis of a branching epithelium GO:0061138 45 0.363
epithelial tube morphogenesis GO:0060562 88 0.245
morphogenesis of a branching structure GO:0001763 45 0.190
regulation of multicellular organismal development GO:2000026 414 0.190
cell division GO:0051301 248 0.158
endocytosis GO:0006897 310 0.151
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.143
gtp catabolic process GO:0006184 72 0.127
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.118
Human
regulation of localization GO:0032879 275 0.117
Mouse
embryonic morphogenesis GO:0048598 206 0.115
transcription from rna polymerase ii promoter GO:0006366 368 0.114
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.109
Human
vesicle mediated transport GO:0016192 381 0.096
Human
regulation of cell development GO:0060284 215 0.096
positive regulation of gene expression GO:0010628 290 0.095
axon development GO:0061564 297 0.095
neurological system process GO:0050877 358 0.092
positive regulation of transcription dna templated GO:0045893 266 0.085
regulation of imaginal disc growth GO:0045570 26 0.081
regulation of neurogenesis GO:0050767 158 0.079
negative regulation of rna metabolic process GO:0051253 251 0.079
actin cytoskeleton organization GO:0030036 206 0.078
response to bacterium GO:0009617 198 0.076
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.076
positive regulation of response to stimulus GO:0048584 323 0.075
positive regulation of nucleic acid templated transcription GO:1903508 266 0.072
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.072
negative regulation of cellular biosynthetic process GO:0031327 277 0.072
nucleoside metabolic process GO:0009116 127 0.071
Human
intracellular signal transduction GO:0035556 300 0.071
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.071
imaginal disc derived appendage morphogenesis GO:0035114 395 0.068
negative regulation of gene expression GO:0010629 387 0.068
negative regulation of biosynthetic process GO:0009890 277 0.067
guanosine containing compound metabolic process GO:1901068 74 0.067
Human
purine nucleotide metabolic process GO:0006163 146 0.067
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.065
programmed cell death GO:0012501 257 0.062
positive regulation of rna metabolic process GO:0051254 271 0.062
ras protein signal transduction GO:0007265 88 0.061
guanosine containing compound catabolic process GO:1901069 74 0.059
Human
regulation of neuron differentiation GO:0045664 103 0.059
compound eye morphogenesis GO:0001745 249 0.058
purine containing compound catabolic process GO:0072523 112 0.058
Human
positive regulation of cellular biosynthetic process GO:0031328 316 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.057
Human
appendage morphogenesis GO:0035107 397 0.057
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
defense response to other organism GO:0098542 225 0.056
organic substance catabolic process GO:1901575 308 0.055
Human
regulation of neuron projection development GO:0010975 69 0.055
cellular catabolic process GO:0044248 372 0.055
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.055
defense response GO:0006952 300 0.054
forebrain development GO:0030900 2 0.054
regulation of axonogenesis GO:0050770 32 0.054
neuroblast proliferation GO:0007405 74 0.053
small molecule metabolic process GO:0044281 305 0.053
Human
positive regulation of nervous system development GO:0051962 69 0.053
cell death GO:0008219 279 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.052
Mouse
glycosyl compound metabolic process GO:1901657 127 0.052
Human
nuclear division GO:0000280 332 0.052
stem cell division GO:0017145 69 0.051
defense response to bacterium GO:0042742 178 0.051
purine nucleotide catabolic process GO:0006195 109 0.050
Human
regulation of ras protein signal transduction GO:0046578 93 0.050
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.050
meiotic cell cycle process GO:1903046 132 0.050
single organism intracellular transport GO:1902582 207 0.048
Human Mouse
immune system process GO:0002376 347 0.047
Mouse
regulation of nervous system development GO:0051960 248 0.047
actin filament organization GO:0007015 126 0.047
gastrulation GO:0007369 70 0.046
cellular protein modification process GO:0006464 438 0.046
developmental programmed cell death GO:0010623 138 0.046
phosphorylation GO:0016310 294 0.044
Mouse
regulation of cell morphogenesis GO:0022604 163 0.043
regulation of intracellular signal transduction GO:1902531 236 0.043
Human Mouse
protein modification process GO:0036211 438 0.043
cellular ketone metabolic process GO:0042180 24 0.043
phagocytosis GO:0006909 215 0.043
eye development GO:0001654 323 0.042
gland morphogenesis GO:0022612 145 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
Human
synapse assembly GO:0007416 143 0.041
cell proliferation GO:0008283 299 0.041
maternal determination of anterior posterior axis embryo GO:0008358 74 0.040
imaginal disc growth GO:0007446 37 0.040
cell maturation GO:0048469 144 0.040
regulation of response to external stimulus GO:0032101 115 0.039
positive regulation of signaling GO:0023056 243 0.039
stem cell proliferation GO:0072089 88 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.038
Human
stem cell differentiation GO:0048863 117 0.037
purine containing compound metabolic process GO:0072521 155 0.037
Human
immune response GO:0006955 246 0.037
post embryonic appendage morphogenesis GO:0035120 385 0.036
regulation of small gtpase mediated signal transduction GO:0051056 93 0.036
Human
stem cell development GO:0048864 79 0.036
ameboidal type cell migration GO:0001667 151 0.036
sensory perception GO:0007600 196 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.036
regulation of ras gtpase activity GO:0032318 38 0.035
Human
heterocycle catabolic process GO:0046700 166 0.035
Human
regulation of cell projection organization GO:0031344 92 0.035
protein catabolic process GO:0030163 101 0.035
glycosyl compound catabolic process GO:1901658 112 0.035
Human
regulation of apoptotic process GO:0042981 130 0.035
positive regulation of signal transduction GO:0009967 223 0.035
purine ribonucleoside metabolic process GO:0046128 127 0.034
Human
localization of cell GO:0051674 257 0.034
biological adhesion GO:0022610 138 0.034
positive regulation of cell communication GO:0010647 250 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
organonitrogen compound metabolic process GO:1901564 318 0.033
Human
negative regulation of transcription dna templated GO:0045892 237 0.033
microtubule polymerization or depolymerization GO:0031109 39 0.033
organophosphate metabolic process GO:0019637 195 0.033
Human
establishment or maintenance of cell polarity GO:0007163 167 0.033
negative regulation of response to stimulus GO:0048585 258 0.033
Mouse
regulation of defense response GO:0031347 102 0.032
carbohydrate metabolic process GO:0005975 82 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.032
Human
regulation of mapk cascade GO:0043408 92 0.032
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.032
salivary gland development GO:0007431 162 0.032
camera type eye development GO:0043010 4 0.031
ribonucleoside triphosphate catabolic process GO:0009203 108 0.031
Human
endosomal vesicle fusion GO:0034058 4 0.031
regulation of protein metabolic process GO:0051246 256 0.031
Human
compound eye development GO:0048749 307 0.031
single organism catabolic process GO:0044712 228 0.030
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
Human
immune response regulating signaling pathway GO:0002764 2 0.030
exocrine system development GO:0035272 162 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.030
Human
establishment of localization in cell GO:0051649 402 0.030
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.030
salivary gland morphogenesis GO:0007435 145 0.030
regulation of response to stress GO:0080134 200 0.030
regulation of developmental growth GO:0048638 174 0.029
regulation of catalytic activity GO:0050790 185 0.029
Human
nucleotide metabolic process GO:0009117 161 0.029
Human
positive regulation of cellular component biogenesis GO:0044089 80 0.029
innate immune response GO:0045087 144 0.029
catabolic process GO:0009056 409 0.029
Human
response to biotic stimulus GO:0009607 294 0.029
retina development in camera type eye GO:0060041 4 0.029
purine nucleoside triphosphate catabolic process GO:0009146 108 0.029
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.028
Human
actin filament based process GO:0030029 220 0.028
regulation of epithelial cell proliferation GO:0050678 4 0.028
positive regulation of ras gtpase activity GO:0032320 36 0.028
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.028
Human
neuromuscular junction development GO:0007528 149 0.028
ribonucleotide catabolic process GO:0009261 109 0.028
Human
somatic stem cell division GO:0048103 37 0.028
negative regulation of signal transduction GO:0009968 206 0.027
Mouse
hindbrain development GO:0030902 2 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.027
Human
regulation of nucleotide catabolic process GO:0030811 48 0.027
Human
organophosphate catabolic process GO:0046434 112 0.027
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
Human
memory GO:0007613 94 0.026
protein ubiquitination GO:0016567 70 0.026
defense response to gram negative bacterium GO:0050829 94 0.026
small gtpase mediated signal transduction GO:0007264 88 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
regulation of cell cycle GO:0051726 291 0.026
positive regulation of lipid metabolic process GO:0045834 4 0.026
nucleoside catabolic process GO:0009164 112 0.026
Human
positive regulation of developmental process GO:0051094 143 0.025
spermatogenesis GO:0007283 200 0.025
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.025
death GO:0016265 284 0.025
salivary gland cell autophagic cell death GO:0035071 83 0.025
negative regulation of epithelial cell proliferation GO:0050680 4 0.025
aromatic compound catabolic process GO:0019439 166 0.025
Human
head development GO:0060322 135 0.025
regulation of nucleoside metabolic process GO:0009118 50 0.025
Human
gtp metabolic process GO:0046039 72 0.025
Human
carbohydrate derivative biosynthetic process GO:1901137 85 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
Human
developmental maturation GO:0021700 172 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
Human
apoptotic process GO:0006915 159 0.024
oocyte construction GO:0007308 112 0.024
sensory organ morphogenesis GO:0090596 260 0.024
regulation of protein complex disassembly GO:0043244 29 0.024
axon regeneration GO:0031103 8 0.024
meiotic cell cycle GO:0051321 171 0.023
oocyte axis specification GO:0007309 108 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
regulation of growth GO:0040008 233 0.023
endodermal cell fate commitment GO:0001711 3 0.023
autophagic cell death GO:0048102 83 0.023
regulation of molecular function GO:0065009 217 0.022
Human
dna methylation or demethylation GO:0044728 4 0.022
macromolecule catabolic process GO:0009057 161 0.022
oocyte differentiation GO:0009994 145 0.022
cation transmembrane transport GO:0098655 88 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
Human
cell motility GO:0048870 251 0.022
nucleotide catabolic process GO:0009166 109 0.022
Human
blastoderm segmentation GO:0007350 159 0.022
negative regulation of cell differentiation GO:0045596 143 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
regulation of purine nucleotide metabolic process GO:1900542 62 0.021
Human
epithelial cell migration GO:0010631 148 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
Human Mouse
eye morphogenesis GO:0048592 260 0.021
synaptic growth at neuromuscular junction GO:0051124 119 0.021
positive regulation of cellular amine metabolic process GO:0033240 0 0.021
molting cycle chitin based cuticle GO:0007591 56 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
Human
single organism carbohydrate metabolic process GO:0044723 72 0.021
cell adhesion GO:0007155 136 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
Human
mesenchymal cell differentiation GO:0048762 1 0.021
detection of stimulus involved in sensory perception GO:0050906 92 0.020
response to other organism GO:0051707 293 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
ribonucleotide metabolic process GO:0009259 145 0.020
Human
cell migration GO:0016477 238 0.020
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.020
stem cell maintenance GO:0019827 67 0.020
regulation of nucleotide metabolic process GO:0006140 62 0.020
Human
g protein coupled receptor signaling pathway GO:0007186 136 0.020
oocyte microtubule cytoskeleton organization GO:0016325 35 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
Human
appendage development GO:0048736 401 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
Human Mouse
heart development GO:0007507 82 0.020
meiotic nuclear division GO:0007126 151 0.019
regulation of innate immune response GO:0045088 71 0.019
single organism biosynthetic process GO:0044711 206 0.019
autophagy GO:0006914 108 0.019
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.019
sensory perception of mechanical stimulus GO:0050954 72 0.019
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.019
protein transport GO:0015031 155 0.019
Mouse
filopodium assembly GO:0046847 33 0.019
regulation of immune system process GO:0002682 176 0.019
Mouse
histolysis GO:0007559 102 0.019
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.019
learning or memory GO:0007611 141 0.019
digestive tract morphogenesis GO:0048546 127 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
Human
asymmetric stem cell division GO:0098722 49 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
Human
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
Human
cellular macromolecule localization GO:0070727 220 0.019
Mouse
regulation of cell differentiation GO:0045595 302 0.018
positive regulation of cell motility GO:2000147 3 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
positive regulation of multicellular organismal process GO:0051240 143 0.018
organic substance transport GO:0071702 257 0.018
Mouse
endoderm formation GO:0001706 3 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.018
Human
positive regulation of gtpase activity GO:0043547 43 0.018
Human
regulation of cellular response to stress GO:0080135 89 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
molting cycle GO:0042303 56 0.018
torc1 signaling GO:0038202 12 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
Human
negative regulation of autophagy GO:0010507 16 0.018
mesenchymal cell development GO:0014031 1 0.018
organelle fission GO:0048285 340 0.018
germ line cyst formation GO:0048134 44 0.018
cellular protein localization GO:0034613 160 0.018
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.018
wing disc morphogenesis GO:0007472 344 0.018
digestive tract development GO:0048565 149 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
negative regulation of cell communication GO:0010648 223 0.018
Mouse
ribonucleoside catabolic process GO:0042454 112 0.018
Human
sister chromatid segregation GO:0000819 92 0.018
positive regulation of developmental growth GO:0048639 62 0.018
developmental induction GO:0031128 3 0.018
response to radiation GO:0009314 155 0.017
anterior posterior pattern specification GO:0009952 136 0.017
spindle organization GO:0007051 253 0.017
positive regulation of cell development GO:0010720 61 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
Human
dna alkylation GO:0006305 4 0.017
regulation of microtubule cytoskeleton organization GO:0070507 41 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
Human
regulation of cell division GO:0051302 72 0.017
response to abiotic stimulus GO:0009628 341 0.017
mitotic spindle organization GO:0007052 220 0.017
gene silencing GO:0016458 138 0.017
positive regulation of mapk cascade GO:0043410 63 0.017
cellular component disassembly GO:0022411 46 0.017
establishment of protein localization GO:0045184 163 0.017
Mouse
jak stat cascade GO:0007259 49 0.017
meiosis i GO:0007127 59 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
Human
male gamete generation GO:0048232 201 0.016
purine ribonucleoside catabolic process GO:0046130 112 0.016
Human
regulation of hydrolase activity GO:0051336 97 0.016
Human
response to axon injury GO:0048678 12 0.016
positive regulation of cell migration GO:0030335 2 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of developmental process GO:0051093 201 0.016
molting cycle process GO:0022404 29 0.016
regulation of programmed cell death GO:0043067 152 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
Human
regulation of immune response GO:0050776 118 0.016
positive regulation of axonogenesis GO:0050772 2 0.016
regulation of response to nutrient levels GO:0032107 18 0.016
mesoderm development GO:0007498 78 0.016
negative regulation of organelle organization GO:0010639 56 0.016
regulation of mitosis GO:0007088 56 0.015
learning GO:0007612 75 0.015
intracellular transport GO:0046907 228 0.015
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.015
response to external biotic stimulus GO:0043207 293 0.015
cell adhesion mediated by integrin GO:0033627 12 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
single organism cellular localization GO:1902580 180 0.015
Mouse
growth GO:0040007 359 0.015
organelle fusion GO:0048284 46 0.015
germarium derived female germ line cyst formation GO:0030727 42 0.015
asymmetric protein localization GO:0008105 33 0.015
fluid transport GO:0042044 19 0.015
regulation of autophagy GO:0010506 62 0.015
regulation of multi organism process GO:0043900 131 0.015
regulation of photoreceptor cell differentiation GO:0046532 34 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
Human
cellular response to chemical stimulus GO:0070887 199 0.014
intracellular protein transport GO:0006886 104 0.014
Mouse
regulation of gtpase activity GO:0043087 44 0.014
Human
hippo signaling GO:0035329 20 0.014
kidney development GO:0001822 3 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
cellular lipid metabolic process GO:0044255 83 0.014
formation of primary germ layer GO:0001704 24 0.014
regulation of stem cell proliferation GO:0072091 40 0.014
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.014
mapk cascade GO:0000165 107 0.014
Mouse
response to nutrient levels GO:0031667 114 0.014
embryonic organ development GO:0048568 50 0.014
malpighian tubule development GO:0072002 64 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
regulation of cell proliferation GO:0042127 163 0.014
germarium derived egg chamber formation GO:0007293 101 0.014
neuronal stem cell division GO:0036445 35 0.014
regulation of synapse assembly GO:0051963 94 0.014
homeostatic process GO:0042592 199 0.014
mitotic nuclear division GO:0007067 213 0.013
cellular protein complex disassembly GO:0043624 35 0.013
cellular response to organic substance GO:0071310 132 0.013
regulation of catabolic process GO:0009894 170 0.013
Human
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.013
establishment of synaptic vesicle localization GO:0097480 50 0.013
protein phosphorylation GO:0006468 169 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
Human
germ cell migration GO:0008354 43 0.013
regulation of cell shape GO:0008360 113 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
proteolysis GO:0006508 192 0.013
Human
oxoacid metabolic process GO:0043436 103 0.013
peripheral nervous system development GO:0007422 52 0.013
cranial nerve development GO:0021545 1 0.013
chromosome segregation GO:0007059 157 0.013
organelle localization GO:0051640 148 0.013
organ growth GO:0035265 56 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
single organism behavior GO:0044708 391 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
central nervous system development GO:0007417 201 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
telencephalon development GO:0021537 2 0.013
regulation of rho gtpase activity GO:0032319 20 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
Human
response to decreased oxygen levels GO:0036293 58 0.012
glial cell development GO:0021782 27 0.012
salivary gland histolysis GO:0035070 88 0.012
synaptic vesicle localization GO:0097479 53 0.012
r7 cell differentiation GO:0045466 43 0.012
detection of stimulus GO:0051606 156 0.012
activation of innate immune response GO:0002218 4 0.012
rho protein signal transduction GO:0007266 14 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
cortical actin cytoskeleton organization GO:0030866 24 0.012
female germ line cyst formation GO:0048135 42 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
protein polymerization GO:0051258 42 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
regulation of cell size GO:0008361 63 0.012
vesicle organization GO:0016050 44 0.012
glycoprotein metabolic process GO:0009100 41 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of transport GO:0051049 181 0.012
Mouse
positive regulation of phosphorylation GO:0042327 87 0.012
positive regulation of synapse assembly GO:0051965 29 0.012
regulation of microtubule based process GO:0032886 49 0.012
positive regulation of nucleotide metabolic process GO:0045981 55 0.012
Human
tissue death GO:0016271 102 0.012
tripartite regional subdivision GO:0007351 103 0.012
cell projection assembly GO:0030031 94 0.012
neural precursor cell proliferation GO:0061351 75 0.011
organic acid metabolic process GO:0006082 103 0.011
secretion by cell GO:0032940 101 0.011
establishment of spindle orientation GO:0051294 18 0.011
lipid metabolic process GO:0006629 121 0.011
epidermis development GO:0008544 65 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
glycoprotein biosynthetic process GO:0009101 41 0.011
rna localization GO:0006403 115 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
negative regulation of cell cycle GO:0045786 116 0.011
water homeostasis GO:0030104 3 0.011
regulation of dna templated transcription elongation GO:0032784 17 0.011
cell junction organization GO:0034330 57 0.011
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
Mouse
negative regulation of cell death GO:0060548 81 0.011
adult behavior GO:0030534 137 0.011
cellular protein catabolic process GO:0044257 83 0.011
gliogenesis GO:0042063 80 0.011
response to fibroblast growth factor GO:0071774 10 0.011
synaptic transmission GO:0007268 288 0.011
digestive system development GO:0055123 149 0.011
positive regulation of lipid biosynthetic process GO:0046889 3 0.010
lipid biosynthetic process GO:0008610 46 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
Human
epithelial cell differentiation GO:0030855 322 0.010
regulation of hemocyte differentiation GO:0045610 22 0.010
centriole assembly GO:0098534 24 0.010
gene silencing by rna GO:0031047 57 0.010
response to hypoxia GO:0001666 53 0.010
positive regulation of cell projection organization GO:0031346 29 0.010
determination of adult lifespan GO:0008340 137 0.010
establishment of organelle localization GO:0051656 122 0.010
cytoskeleton dependent intracellular transport GO:0030705 44 0.010
regulation of cell fate commitment GO:0010453 29 0.010
negative regulation of immune system process GO:0002683 50 0.010
Mouse
axis specification GO:0009798 167 0.010
cellularization GO:0007349 90 0.010
response to lipopolysaccharide GO:0032496 4 0.010
regulation of response to extracellular stimulus GO:0032104 18 0.010
brain development GO:0007420 120 0.010
neuroblast division GO:0055057 35 0.010
developmental growth GO:0048589 280 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
multicellular organismal aging GO:0010259 140 0.010
golgi organization GO:0007030 66 0.010
positive regulation of neuron apoptotic process GO:0043525 1 0.010

wkd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.069
cancer DOID:162 0 0.057
organ system cancer DOID:0050686 0 0.051
nervous system disease DOID:863 0 0.034
disease of anatomical entity DOID:7 0 0.034
cardiovascular system disease DOID:1287 0 0.019
vascular disease DOID:178 0 0.019
artery disease DOID:0050828 0 0.019
musculoskeletal system disease DOID:17 0 0.014