Drosophila melanogaster

143 known processes

alphaTub85E (Dmel_CG9476)

alpha-Tubulin at 85E

(Aliases: 2t,CG9476,a2t,alphaTub84E,ALPHA 85E,alpha-Tub85E,DTA3,Dmel\CG9476,alphaTub2,alpha2t,alpha-Tub,alpha85E-tub,T,alphaTub,alpha-tubulin,Tub,alpha2,alpha85E,aTub85E)

alphaTub85E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid differentiation GO:0048515 114 0.316
negative regulation of gene expression GO:0010629 387 0.128
proteolysis GO:0006508 192 0.119
spermatogenesis GO:0007283 200 0.114
regulation of cellular protein metabolic process GO:0032268 243 0.092
protein modification process GO:0036211 438 0.084
vesicle mediated transport GO:0016192 381 0.081
cellular protein modification process GO:0006464 438 0.075
positive regulation of macromolecule metabolic process GO:0010604 405 0.074
phagocytosis GO:0006909 215 0.070
cell death GO:0008219 279 0.068
spermatid development GO:0007286 98 0.067
regulation of synapse structure and activity GO:0050803 128 0.063
regulation of multicellular organismal development GO:2000026 414 0.063
programmed cell death GO:0012501 257 0.060
regulation of proteolysis GO:0030162 87 0.058
regulation of intracellular signal transduction GO:1902531 236 0.054
death GO:0016265 284 0.053
regulation of endopeptidase activity GO:0052548 36 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.052
cell cell signaling involved in cell fate commitment GO:0045168 210 0.052
protein maturation GO:0051604 71 0.052
exocrine system development GO:0035272 162 0.050
taxis GO:0042330 304 0.049
salivary gland morphogenesis GO:0007435 145 0.048
defense response GO:0006952 300 0.048
positive regulation of proteolysis GO:0045862 52 0.045
endocytosis GO:0006897 310 0.045
regulation of cell death GO:0010941 173 0.044
macromolecule catabolic process GO:0009057 161 0.043
intracellular signal transduction GO:0035556 300 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
male gamete generation GO:0048232 201 0.042
regulation of programmed cell death GO:0043067 152 0.042
organic substance transport GO:0071702 257 0.042
response to abiotic stimulus GO:0009628 341 0.041
organic substance catabolic process GO:1901575 308 0.040
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.040
microtubule organizing center organization GO:0031023 168 0.040
sperm individualization GO:0007291 48 0.039
regulation of cell differentiation GO:0045595 302 0.038
apoptotic process GO:0006915 159 0.037
axon development GO:0061564 297 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.036
regulation of response to stress GO:0080134 200 0.036
cytoskeleton dependent cytokinesis GO:0061640 81 0.036
Fly
catabolic process GO:0009056 409 0.036
organic acid metabolic process GO:0006082 103 0.035
response to other organism GO:0051707 293 0.035
Fly
mitotic cytokinesis GO:0000281 50 0.034
Fly
cell division GO:0051301 248 0.034
lateral inhibition GO:0046331 206 0.034
regulation of synapse organization GO:0050807 110 0.034
negative regulation of signaling GO:0023057 219 0.034
centrosome organization GO:0051297 163 0.034
regulation of cysteine type endopeptidase activity GO:2000116 27 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
synapse organization GO:0050808 196 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
oxoacid metabolic process GO:0043436 103 0.032
negative regulation of cell communication GO:0010648 223 0.032
regulation of cell development GO:0060284 215 0.031
immune system process GO:0002376 347 0.031
Fly
regulation of protein metabolic process GO:0051246 256 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
wing disc morphogenesis GO:0007472 344 0.030
cellularization GO:0007349 90 0.030
cytoplasmic transport GO:0016482 130 0.029
histolysis GO:0007559 102 0.029
zymogen activation GO:0031638 20 0.028
homeostatic process GO:0042592 199 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
regulation of apoptotic process GO:0042981 130 0.028
carboxylic acid metabolic process GO:0019752 92 0.027
immune response GO:0006955 246 0.027
Fly
gland morphogenesis GO:0022612 145 0.026
salivary gland development GO:0007431 162 0.026
regulation of peptidase activity GO:0052547 39 0.026
gland development GO:0048732 191 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
regulation of cell cycle GO:0051726 291 0.026
small molecule metabolic process GO:0044281 305 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
positive regulation of molecular function GO:0044093 136 0.025
body morphogenesis GO:0010171 2 0.025
axonogenesis GO:0007409 290 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
regulation of catabolic process GO:0009894 170 0.025
developmental programmed cell death GO:0010623 138 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
epithelial cell development GO:0002064 274 0.024
central nervous system development GO:0007417 201 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
defense response to other organism GO:0098542 225 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
positive regulation of gene expression GO:0010628 290 0.023
tissue death GO:0016271 102 0.023
segmentation GO:0035282 207 0.023
growth GO:0040007 359 0.023
epithelial cell differentiation GO:0030855 322 0.023
negative regulation of signal transduction GO:0009968 206 0.023
membrane organization GO:0061024 112 0.022
regulation of molecular function GO:0065009 217 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
cellular catabolic process GO:0044248 372 0.022
regulation of anatomical structure size GO:0090066 163 0.022
regulation of hydrolase activity GO:0051336 97 0.022
regulation of nervous system development GO:0051960 248 0.022
positive regulation of peptidase activity GO:0010952 29 0.022
protein localization GO:0008104 284 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
regulation of neurogenesis GO:0050767 158 0.021
organelle assembly GO:0070925 198 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
reproductive structure development GO:0048608 74 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
protein ubiquitination GO:0016567 70 0.021
compound eye development GO:0048749 307 0.020
response to biotic stimulus GO:0009607 294 0.020
Fly
positive regulation of response to stimulus GO:0048584 323 0.020
positive regulation of cell death GO:0010942 69 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
intracellular transport GO:0046907 228 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
cell proliferation GO:0008283 299 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
protein processing GO:0016485 68 0.019
chromosome organization GO:0051276 360 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
regulation of defense response GO:0031347 102 0.019
cell migration GO:0016477 238 0.019
response to organic substance GO:0010033 284 0.019
regionalization GO:0003002 416 0.019
response to external biotic stimulus GO:0043207 293 0.019
Fly
positive regulation of signal transduction GO:0009967 223 0.019
single organism biosynthetic process GO:0044711 206 0.018
organelle fission GO:0048285 340 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
axis specification GO:0009798 167 0.018
regulation of organelle organization GO:0033043 196 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
positive regulation of cell communication GO:0010647 250 0.018
nucleotide metabolic process GO:0009117 161 0.018
appendage development GO:0048736 401 0.018
positive regulation of endopeptidase activity GO:0010950 26 0.018
protein catabolic process GO:0030163 101 0.017
establishment of localization in cell GO:0051649 402 0.017
chemotaxis GO:0006935 249 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
activation of cysteine type endopeptidase activity GO:0097202 17 0.017
striated muscle cell differentiation GO:0051146 90 0.017
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.017
positive regulation of catalytic activity GO:0043085 118 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
positive regulation of transport GO:0051050 92 0.016
establishment of protein localization GO:0045184 163 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.016
defense response to bacterium GO:0042742 178 0.016
muscle structure development GO:0061061 224 0.016
single organism behavior GO:0044708 391 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
macromolecular complex assembly GO:0065003 256 0.016
response to oxidative stress GO:0006979 86 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
regulation of immune system process GO:0002682 176 0.015
appendage morphogenesis GO:0035107 397 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
autophagic cell death GO:0048102 83 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
single organism intracellular transport GO:1902582 207 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
regulation of localization GO:0032879 275 0.015
positive regulation of developmental process GO:0051094 143 0.015
phosphorylation GO:0016310 294 0.015
localization of cell GO:0051674 257 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
organophosphate metabolic process GO:0019637 195 0.015
eye morphogenesis GO:0048592 260 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
actin filament based process GO:0030029 220 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
cellular amine metabolic process GO:0044106 12 0.014
spindle organization GO:0007051 253 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
regulation of cell proliferation GO:0042127 163 0.014
respiratory system development GO:0060541 213 0.014
cholesterol homeostasis GO:0042632 3 0.014
cell cycle phase transition GO:0044770 140 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
eye development GO:0001654 323 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
negative regulation of biosynthetic process GO:0009890 277 0.013
response to radiation GO:0009314 155 0.013
compound eye morphogenesis GO:0001745 249 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
amine metabolic process GO:0009308 12 0.013
nuclear division GO:0000280 332 0.013
regulation of catalytic activity GO:0050790 185 0.013
protein transport GO:0015031 155 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
cell motility GO:0048870 251 0.013
mitotic spindle organization GO:0007052 220 0.013
cellular protein localization GO:0034613 160 0.013
single organism catabolic process GO:0044712 228 0.013
cellular protein catabolic process GO:0044257 83 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
cell growth GO:0016049 108 0.012
regulation of growth GO:0040008 233 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
response to glucose GO:0009749 2 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
synapse assembly GO:0007416 143 0.012
regulation of cellular localization GO:0060341 136 0.012
response to wounding GO:0009611 94 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
response to bacterium GO:0009617 198 0.012
ovarian follicle cell development GO:0030707 248 0.012
negative regulation of cell cycle GO:0045786 116 0.012
regulation of cellular response to stress GO:0080135 89 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
negative regulation of developmental process GO:0051093 201 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
neuromuscular junction development GO:0007528 149 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of immune response GO:0050776 118 0.012
cell maturation GO:0048469 144 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
actin cytoskeleton organization GO:0030036 206 0.011
positive regulation of cell development GO:0010720 61 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
regulation of neuron differentiation GO:0045664 103 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
response to hexose GO:0009746 3 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
mitotic nuclear division GO:0007067 213 0.011
single organism membrane organization GO:0044802 93 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
sensory organ morphogenesis GO:0090596 260 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
chaeta development GO:0022416 97 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
positive regulation of cell differentiation GO:0045597 64 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
sterol homeostasis GO:0055092 4 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
regulation of cell cycle process GO:0010564 181 0.010
dendrite development GO:0016358 204 0.010
response to monosaccharide GO:0034284 4 0.010
tissue morphogenesis GO:0048729 297 0.010

alphaTub85E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.020