Drosophila melanogaster

15 known processes

CycK (Dmel_CG15218)

Cyclin K

(Aliases: Dmel\CG15218,CG15218)

CycK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic g2 m transition checkpoint GO:0044818 70 0.527
positive regulation of macromolecule metabolic process GO:0010604 405 0.522
dna integrity checkpoint GO:0031570 81 0.509
positive regulation of rna metabolic process GO:0051254 271 0.434
positive regulation of nucleic acid templated transcription GO:1903508 266 0.290
cognition GO:0050890 141 0.270
positive regulation of gene expression GO:0010628 290 0.266
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.258
histone modification GO:0016570 106 0.233
chromatin modification GO:0016568 147 0.229
mitotic cell cycle phase transition GO:0044772 138 0.227
positive regulation of rna biosynthetic process GO:1902680 266 0.212
covalent chromatin modification GO:0016569 106 0.198
dna damage checkpoint GO:0000077 78 0.171
mitotic cell cycle checkpoint GO:0007093 88 0.158
chromatin organization GO:0006325 207 0.158
mitotic dna damage checkpoint GO:0044773 74 0.154
negative regulation of signaling GO:0023057 219 0.144
g2 dna damage checkpoint GO:0031572 69 0.136
regulation of cell cycle process GO:0010564 181 0.134
growth GO:0040007 359 0.131
regulation of cell cycle phase transition GO:1901987 130 0.127
positive regulation of transcription dna templated GO:0045893 266 0.127
protein modification process GO:0036211 438 0.126
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.123
mitotic dna integrity checkpoint GO:0044774 75 0.121
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.119
spindle organization GO:0007051 253 0.114
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.103
cell cycle checkpoint GO:0000075 95 0.100
positive regulation of biosynthetic process GO:0009891 316 0.093
positive regulation of cell communication GO:0010647 250 0.090
negative regulation of cell cycle phase transition GO:1901988 103 0.086
chromosome organization GO:0051276 360 0.077
negative regulation of gene expression GO:0010629 387 0.077
negative regulation of cell cycle process GO:0010948 109 0.075
regulation of cell proliferation GO:0042127 163 0.075
cellular protein modification process GO:0006464 438 0.075
cellular protein catabolic process GO:0044257 83 0.074
protein catabolic process GO:0030163 101 0.074
cell cycle phase transition GO:0044770 140 0.072
regulation of multicellular organismal development GO:2000026 414 0.071
phosphorylation GO:0016310 294 0.070
regulation of mitotic cell cycle phase transition GO:1901990 130 0.068
organelle fission GO:0048285 340 0.067
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.065
regulation of mitotic cell cycle GO:0007346 190 0.063
modification dependent protein catabolic process GO:0019941 78 0.063
camera type eye development GO:0043010 4 0.062
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.060
protein complex assembly GO:0006461 200 0.058
cellular macromolecule catabolic process GO:0044265 136 0.058
regulation of rna splicing GO:0043484 69 0.057
wing disc morphogenesis GO:0007472 344 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.052
tripartite regional subdivision GO:0007351 103 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.050
proteolysis GO:0006508 192 0.050
regulation of phosphorylation GO:0042325 147 0.049
regulation of protein catabolic process GO:0042176 55 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.048
mitotic cell cycle embryonic GO:0045448 38 0.048
transcription from rna polymerase ii promoter GO:0006366 368 0.047
catabolic process GO:0009056 409 0.046
rna processing GO:0006396 147 0.046
molting cycle chitin based cuticle GO:0007591 56 0.045
meiosis i GO:0007127 59 0.045
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
negative regulation of cell cycle GO:0045786 116 0.040
regulation of proteolysis GO:0030162 87 0.040
negative regulation of protein metabolic process GO:0051248 85 0.040
regulation of neural precursor cell proliferation GO:2000177 35 0.040
apoptotic process GO:0006915 159 0.039
histone deacetylation GO:0016575 9 0.037
phagocytosis GO:0006909 215 0.036
proteasomal protein catabolic process GO:0010498 59 0.035
regulation of organelle organization GO:0033043 196 0.033
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.032
regulation of nervous system development GO:0051960 248 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
larval development GO:0002164 104 0.032
regulation of protein metabolic process GO:0051246 256 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
negative regulation of cell proliferation GO:0008285 69 0.029
mitotic g2 dna damage checkpoint GO:0007095 69 0.029
single organism behavior GO:0044708 391 0.028
death GO:0016265 284 0.028
regulation of apoptotic process GO:0042981 130 0.027
cell death GO:0008219 279 0.027
negative regulation of mitotic cell cycle GO:0045930 109 0.027
extrinsic apoptotic signaling pathway GO:0097191 1 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
programmed cell death GO:0012501 257 0.024
meiotic cell cycle GO:0051321 171 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
Mouse
endocytosis GO:0006897 310 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
cellular macromolecule localization GO:0070727 220 0.023
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.022
ubiquitin dependent protein catabolic process GO:0006511 78 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
dna packaging GO:0006323 91 0.022
developmental maturation GO:0021700 172 0.021
regulation of cell development GO:0060284 215 0.021
meiotic cell cycle process GO:1903046 132 0.021
axon development GO:0061564 297 0.021
regulation of meiosis GO:0040020 3 0.020
mrna processing GO:0006397 104 0.020
mrna metabolic process GO:0016071 124 0.020
macromolecule deacylation GO:0098732 11 0.019
regulation of cellular protein catabolic process GO:1903362 44 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
body morphogenesis GO:0010171 2 0.018
organic substance transport GO:0071702 257 0.018
modification dependent macromolecule catabolic process GO:0043632 79 0.018
regulation of phosphatase activity GO:0010921 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
erk1 and erk2 cascade GO:0070371 39 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
adult behavior GO:0030534 137 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
gene silencing GO:0016458 138 0.015
response to oxygen containing compound GO:1901700 200 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
adult locomotory behavior GO:0008344 76 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of programmed cell death GO:0043067 152 0.015
cell proliferation GO:0008283 299 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
vesicle mediated transport GO:0016192 381 0.014
protein processing GO:0016485 68 0.014
negative regulation of nervous system development GO:0051961 92 0.014
regulation of cell cycle GO:0051726 291 0.013
g1 s transition of mitotic cell cycle GO:0000082 31 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
determination of adult lifespan GO:0008340 137 0.013
rna capping GO:0036260 1 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
positive regulation of programmed cell death GO:0043068 62 0.013
regulation of cell differentiation GO:0045595 302 0.013
regulation of mapk cascade GO:0043408 92 0.012
regulation of molecular function GO:0065009 217 0.012
mitochondrion organization GO:0007005 65 0.012
ras protein signal transduction GO:0007265 88 0.012
chaeta morphogenesis GO:0008407 42 0.012
regulation of catalytic activity GO:0050790 185 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
reproductive structure development GO:0048608 74 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
regulation of protein modification process GO:0031399 112 0.011
multicellular organismal aging GO:0010259 140 0.011
connective tissue development GO:0061448 3 0.011
rna splicing GO:0008380 83 0.011
appendage development GO:0048736 401 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
protein maturation GO:0051604 71 0.011
spinal cord development GO:0021510 1 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
developmental growth GO:0048589 280 0.010
positive regulation of signal transduction GO:0009967 223 0.010
regulation of histone deacetylation GO:0031063 2 0.010
regulation of neurogenesis GO:0050767 158 0.010

CycK disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.104
organ system cancer DOID:0050686 0 0.104
disease of cellular proliferation DOID:14566 0 0.104
disease of anatomical entity DOID:7 0 0.027