Drosophila melanogaster

47 known processes

ifc (Dmel_CG9078)

infertile crescent

(Aliases: l(2)gdh-2,DES-1,des-1,Dmel\CG9078,l(2)26Ab,des1,ms(2)04875,CG9078,des)

ifc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cytokinesis GO:0033206 33 0.978
male meiosis cytokinesis GO:0007112 26 0.968
spermatocyte division GO:0048137 13 0.964
cytokinesis GO:0000910 90 0.763
male gamete generation GO:0048232 201 0.489
spermatogenesis GO:0007283 200 0.412
meiosis ii GO:0007135 23 0.318
meiosis ii cytokinesis GO:0007111 11 0.311
transmembrane transport GO:0055085 139 0.259
cytokinetic process GO:0032506 27 0.258
cell division GO:0051301 248 0.241
cytoskeleton dependent cytokinesis GO:0061640 81 0.237
lipid metabolic process GO:0006629 121 0.220
protein complex disassembly GO:0043241 36 0.203
regulation of anatomical structure size GO:0090066 163 0.161
meiosis i cytokinesis GO:0007110 12 0.149
spermatid development GO:0007286 98 0.147
regulation of anatomical structure morphogenesis GO:0022603 242 0.142
death GO:0016265 284 0.140
cortical actin cytoskeleton organization GO:0030866 24 0.137
contractile ring contraction GO:0036213 12 0.129
regulation of localization GO:0032879 275 0.125
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.120
cellular catabolic process GO:0044248 372 0.117
protein prenylation GO:0018342 3 0.111
growth GO:0040007 359 0.101
regulation of protein complex disassembly GO:0043244 29 0.100
proteolysis GO:0006508 192 0.097
organelle assembly GO:0070925 198 0.096
purine ribonucleoside metabolic process GO:0046128 127 0.090
cellular nitrogen compound catabolic process GO:0044270 165 0.087
positive regulation of response to stimulus GO:0048584 323 0.086
mitotic nuclear division GO:0007067 213 0.086
spindle assembly GO:0051225 80 0.083
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.082
establishment of protein localization to peroxisome GO:0072663 2 0.082
organophosphate metabolic process GO:0019637 195 0.081
organic substance transport GO:0071702 257 0.080
cellular response to oxygen containing compound GO:1901701 79 0.078
peroxisome organization GO:0007031 14 0.077
meiotic cell cycle process GO:1903046 132 0.076
negative regulation of cytoskeleton organization GO:0051494 30 0.075
oxoacid metabolic process GO:0043436 103 0.073
very long chain fatty acid catabolic process GO:0042760 2 0.070
organonitrogen compound metabolic process GO:1901564 318 0.069
negative regulation of protein depolymerization GO:1901880 23 0.064
cortical cytoskeleton organization GO:0030865 29 0.064
ion transport GO:0006811 145 0.063
peptide metabolic process GO:0006518 80 0.062
small molecule metabolic process GO:0044281 305 0.062
nucleus organization GO:0006997 45 0.061
protein complex biogenesis GO:0070271 201 0.061
single organism catabolic process GO:0044712 228 0.060
cellular protein complex disassembly GO:0043624 35 0.060
protein depolymerization GO:0051261 31 0.059
negative regulation of gene expression GO:0010629 387 0.057
organic acid metabolic process GO:0006082 103 0.056
nucleobase containing small molecule metabolic process GO:0055086 174 0.056
regulation of protein depolymerization GO:1901879 27 0.056
nucleoside triphosphate metabolic process GO:0009141 120 0.055
embryonic pattern specification GO:0009880 174 0.055
regulation of transport GO:0051049 181 0.053
metal ion transport GO:0030001 74 0.052
catabolic process GO:0009056 409 0.051
atp metabolic process GO:0046034 49 0.051
establishment of protein localization GO:0045184 163 0.051
response to lipopolysaccharide GO:0032496 4 0.050
cellular amide metabolic process GO:0043603 80 0.050
negative regulation of phosphatase activity GO:0010923 3 0.049
cellular response to organic substance GO:0071310 132 0.049
programmed cell death GO:0012501 257 0.048
regulation of cell cycle process GO:0010564 181 0.048
meiotic cell cycle GO:0051321 171 0.048
actin filament capping GO:0051693 2 0.048
membrane tubulation GO:0097320 4 0.047
positive regulation of multicellular organismal process GO:0051240 143 0.047
protein localization to peroxisome GO:0072662 2 0.046
nucleobase containing compound catabolic process GO:0034655 165 0.044
neuroblast proliferation GO:0007405 74 0.044
macromolecular complex assembly GO:0065003 256 0.043
cellularization GO:0007349 90 0.043
regulation of organ morphogenesis GO:2000027 78 0.043
carbohydrate derivative metabolic process GO:1901135 217 0.042
immune effector process GO:0002252 98 0.042
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.042
regulation of multicellular organismal development GO:2000026 414 0.042
rna localization GO:0006403 115 0.040
response to alcohol GO:0097305 95 0.039
organic substance catabolic process GO:1901575 308 0.039
ribonucleoside monophosphate catabolic process GO:0009158 39 0.038
purine nucleoside monophosphate catabolic process GO:0009128 38 0.038
protein transmembrane transport GO:0071806 4 0.038
intracellular mrna localization GO:0008298 66 0.038
unidimensional cell growth GO:0009826 15 0.038
response to organic substance GO:0010033 284 0.037
centrosome organization GO:0051297 163 0.036
cell death GO:0008219 279 0.036
developmental growth involved in morphogenesis GO:0060560 65 0.035
organelle fission GO:0048285 340 0.035
regulation of cell cycle GO:0051726 291 0.034
regulation of spindle organization GO:0090224 17 0.034
gland development GO:0048732 191 0.034
establishment of localization in cell GO:0051649 402 0.033
regulation of developmental growth GO:0048638 174 0.033
regulation of ion transport GO:0043269 39 0.032
negative regulation of endopeptidase activity GO:0010951 11 0.032
sperm individualization GO:0007291 48 0.031
ribonucleoside triphosphate catabolic process GO:0009203 108 0.031
nucleoside metabolic process GO:0009116 127 0.031
protein heterooligomerization GO:0051291 4 0.031
cholesterol homeostasis GO:0042632 3 0.031
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.031
sensory perception GO:0007600 196 0.031
regulation of growth GO:0040008 233 0.031
small gtpase mediated signal transduction GO:0007264 88 0.030
response to glucose GO:0009749 2 0.030
cell recognition GO:0008037 102 0.030
cation transport GO:0006812 110 0.029
xenobiotic transport GO:0042908 1 0.029
regulation of microtubule cytoskeleton organization GO:0070507 41 0.029
protein targeting to peroxisome GO:0006625 2 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
retinal cell programmed cell death GO:0046666 25 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.028
intracellular transport GO:0046907 228 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
meiotic nuclear division GO:0007126 151 0.028
protein geranylgeranylation GO:0018344 3 0.028
kidney development GO:0001822 3 0.028
regulation of steroid metabolic process GO:0019218 2 0.027
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
aromatic compound catabolic process GO:0019439 166 0.027
protein transport GO:0015031 155 0.026
compound eye development GO:0048749 307 0.026
regulation of phosphatase activity GO:0010921 3 0.026
response to wounding GO:0009611 94 0.026
apoptotic process GO:0006915 159 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
blood circulation GO:0008015 26 0.025
ras protein signal transduction GO:0007265 88 0.025
heterocycle catabolic process GO:0046700 166 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
nucleoside monophosphate metabolic process GO:0009123 52 0.024
positive regulation of developmental process GO:0051094 143 0.024
peroxisomal transport GO:0043574 2 0.024
regulation of catabolic process GO:0009894 170 0.024
vesicle mediated transport GO:0016192 381 0.024
oocyte fate determination GO:0030716 27 0.024
carbohydrate derivative catabolic process GO:1901136 118 0.024
cellular lipid metabolic process GO:0044255 83 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
regulation of protein localization GO:0032880 76 0.023
axis specification GO:0009798 167 0.023
spindle stabilization GO:0043146 14 0.023
embryonic axis specification GO:0000578 107 0.023
macromolecular complex disassembly GO:0032984 37 0.022
phosphorylation GO:0016310 294 0.022
regulation of cell division GO:0051302 72 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
regulation of establishment of protein localization GO:0070201 61 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
regulation of cell morphogenesis GO:0022604 163 0.022
prenylation GO:0097354 3 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
secondary metabolic process GO:0019748 75 0.022
defense response GO:0006952 300 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
single organism behavior GO:0044708 391 0.021
purine containing compound metabolic process GO:0072521 155 0.021
cytoplasmic transport GO:0016482 130 0.021
cell growth GO:0016049 108 0.021
very long chain fatty acid metabolic process GO:0000038 4 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
fatty acid metabolic process GO:0006631 20 0.021
peripheral nervous system development GO:0007422 52 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
lipid biosynthetic process GO:0008610 46 0.020
intracellular signal transduction GO:0035556 300 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
actin filament depolymerization GO:0030042 5 0.020
immune response GO:0006955 246 0.020
cellular component disassembly GO:0022411 46 0.020
negative regulation of biosynthetic process GO:0009890 277 0.020
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
response to oxygen containing compound GO:1901700 200 0.020
biological adhesion GO:0022610 138 0.019
spindle organization GO:0007051 253 0.019
single organism biosynthetic process GO:0044711 206 0.019
lipid catabolic process GO:0016042 21 0.019
intracellular protein transport GO:0006886 104 0.018
retina development in camera type eye GO:0060041 4 0.018
arp2 3 complex mediated actin nucleation GO:0034314 3 0.018
spindle assembly involved in mitosis GO:0090307 50 0.018
regulation of cell size GO:0008361 63 0.018
meiotic spindle stabilization GO:0043147 8 0.018
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
purine nucleoside monophosphate metabolic process GO:0009126 50 0.017
protein import GO:0017038 55 0.017
atp catabolic process GO:0006200 38 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
response to ionizing radiation GO:0010212 32 0.017
positive regulation of signal transduction GO:0009967 223 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
cell migration GO:0016477 238 0.017
regulation of viral genome replication GO:0045069 4 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
developmental growth GO:0048589 280 0.017
actin filament based process GO:0030029 220 0.017
chemical homeostasis GO:0048878 92 0.016
positive regulation of defense response GO:0031349 59 0.016
endocytosis GO:0006897 310 0.016
nucleoside catabolic process GO:0009164 112 0.016
intracellular protein transmembrane import GO:0044743 4 0.016
body morphogenesis GO:0010171 2 0.016
molting cycle chitin based cuticle GO:0007591 56 0.016
anion transport GO:0006820 41 0.016
skeletal muscle fiber development GO:0048741 3 0.016
localization of cell GO:0051674 257 0.016
pseudocleavage GO:0030588 9 0.016
microtubule polymerization or depolymerization GO:0031109 39 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
glial cell development GO:0021782 27 0.015
purine containing compound catabolic process GO:0072523 112 0.015
cellular macromolecule localization GO:0070727 220 0.015
drug transport GO:0015893 2 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
intracellular protein transmembrane transport GO:0065002 4 0.015
actin cytoskeleton organization GO:0030036 206 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.015
larval development GO:0002164 104 0.015
secretion GO:0046903 109 0.015
actomyosin contractile ring contraction GO:0000916 12 0.015
internal peptidyl lysine acetylation GO:0018393 38 0.015
regulation of nervous system development GO:0051960 248 0.015
blastoderm segmentation GO:0007350 159 0.015
regulation of catalytic activity GO:0050790 185 0.015
nucleotide metabolic process GO:0009117 161 0.014
organic acid transport GO:0015849 18 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
steroid metabolic process GO:0008202 20 0.014
tube development GO:0035295 244 0.014
protein polymerization GO:0051258 42 0.014
cardiovascular system development GO:0072358 82 0.014
alcohol biosynthetic process GO:0046165 14 0.014
regulation of ion transmembrane transport GO:0034765 27 0.014
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
regulation of microtubule based process GO:0032886 49 0.013
arf protein signal transduction GO:0032011 2 0.013
regulation of cellular component size GO:0032535 98 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.013
sphingolipid metabolic process GO:0006665 19 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
response to biotic stimulus GO:0009607 294 0.013
cell proliferation GO:0008283 299 0.013
oocyte maturation GO:0001556 3 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
sterol homeostasis GO:0055092 4 0.013
positive regulation of catabolic process GO:0009896 105 0.013
regionalization GO:0003002 416 0.013
protein localization GO:0008104 284 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
regulation of protein transport GO:0051223 57 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
regulation of phosphorylation GO:0042325 147 0.012
organelle fusion GO:0048284 46 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
regulation of actin filament depolymerization GO:0030834 3 0.012
regulation of immune response GO:0050776 118 0.012
cell adhesion GO:0007155 136 0.012
rac protein signal transduction GO:0016601 3 0.012
cellular protein localization GO:0034613 160 0.012
telencephalon development GO:0021537 2 0.012
heart process GO:0003015 37 0.012
regulation of cellular component movement GO:0051270 42 0.012
regulation of synapse organization GO:0050807 110 0.012
acid secretion GO:0046717 1 0.012
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.012
regulation of cell proliferation GO:0042127 163 0.012
cell aging GO:0007569 2 0.012
regulation of actin filament polymerization GO:0030833 25 0.012
compound eye retinal cell programmed cell death GO:0046667 23 0.011
protein complex assembly GO:0006461 200 0.011
segmentation GO:0035282 207 0.011
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.011
cellular protein modification process GO:0006464 438 0.011
microtubule organizing center organization GO:0031023 168 0.011
muscle cell migration GO:0014812 3 0.011
eye photoreceptor cell development GO:0042462 81 0.011
negative regulation of cell communication GO:0010648 223 0.011
heart contraction GO:0060047 26 0.011
extracellular structure organization GO:0043062 46 0.011
protein modification process GO:0036211 438 0.011
regulation of programmed cell death GO:0043067 152 0.011
regulation of hemocyte proliferation GO:0035206 37 0.010
cell motility GO:0048870 251 0.010
sensory perception of sound GO:0007605 56 0.010
spermatid differentiation GO:0048515 114 0.010
regulation of cell development GO:0060284 215 0.010
response to hexose GO:0009746 3 0.010
protein acylation GO:0043543 42 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
anterior posterior axis specification GO:0009948 109 0.010
negative regulation of signal transduction GO:0009968 206 0.010
humoral immune response GO:0006959 117 0.010
actin nucleation GO:0045010 8 0.010

ifc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.119
nervous system disease DOID:863 0 0.048