Drosophila melanogaster

99 known processes

fru (Dmel_CG14307)

fruitless

(Aliases: BTB-VI,ms(3)06411,Fru,Dmel\CG14307,fty,Dmfru,CG7689,CG7688,CT22773,BtbVI,cg7689,FRU,CG7690,cg7688,CG14307,sat)

fru biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mating GO:0007618 120 1.000
mating behavior GO:0007617 106 1.000
multi organism behavior GO:0051705 175 1.000
multicellular organismal reproductive behavior GO:0033057 110 1.000
reproductive behavior GO:0019098 122 1.000
multi organism reproductive behavior GO:0044705 121 1.000
male mating behavior GO:0060179 70 1.000
male courtship behavior GO:0008049 63 1.000
male courtship behavior veined wing extension GO:0048065 22 1.000
multi multicellular organism process GO:0044706 123 1.000
courtship behavior GO:0007619 68 1.000
single organism behavior GO:0044708 391 0.997
neurological system process GO:0050877 358 0.995
taxis GO:0042330 304 0.993
male courtship behavior veined wing vibration GO:0016545 21 0.989
central nervous system development GO:0007417 201 0.983
regulation of multicellular organismal development GO:2000026 414 0.964
response to abiotic stimulus GO:0009628 341 0.937
positive regulation of cellular biosynthetic process GO:0031328 316 0.933
female mating behavior GO:0060180 30 0.928
positive regulation of biosynthetic process GO:0009891 316 0.859
regulation of imaginal disc derived wing size GO:0044719 20 0.859
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.857
positive regulation of gene expression GO:0010628 290 0.845
regulation of anatomical structure morphogenesis GO:0022603 242 0.843
chemosensory behavior GO:0007635 106 0.840
locomotory behavior GO:0007626 176 0.825
head development GO:0060322 135 0.814
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.799
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.785
circadian rhythm GO:0007623 105 0.784
response to organic substance GO:0010033 284 0.780
sensory perception GO:0007600 196 0.768
regulation of nervous system development GO:0051960 248 0.766
negative regulation of rna metabolic process GO:0051253 251 0.751
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.744
learning or memory GO:0007611 141 0.695
positive regulation of nucleic acid templated transcription GO:1903508 266 0.690
negative regulation of gene expression GO:0010629 387 0.680
regulation of organ morphogenesis GO:2000027 78 0.652
negative regulation of transcription dna templated GO:0045892 237 0.647
developmental growth GO:0048589 280 0.632
positive regulation of rna biosynthetic process GO:1902680 266 0.630
negative regulation of response to stimulus GO:0048585 258 0.574
olfactory behavior GO:0042048 97 0.568
imaginal disc derived appendage morphogenesis GO:0035114 395 0.556
regulation of female receptivity GO:0045924 24 0.556
negative regulation of cellular biosynthetic process GO:0031327 277 0.555
axonogenesis GO:0007409 290 0.552
positive regulation of macromolecule metabolic process GO:0010604 405 0.547
aggressive behavior GO:0002118 63 0.511
cell proliferation GO:0008283 299 0.493
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.480
regulation of cell differentiation GO:0045595 302 0.474
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.471
cellular response to chemical stimulus GO:0070887 199 0.471
negative regulation of rna biosynthetic process GO:1902679 240 0.462
muscle structure development GO:0061061 224 0.446
post embryonic appendage morphogenesis GO:0035120 385 0.446
response to oxygen containing compound GO:1901700 200 0.443
negative regulation of signaling GO:0023057 219 0.443
negative regulation of cell communication GO:0010648 223 0.438
response to temperature stimulus GO:0009266 106 0.433
transcription from rna polymerase ii promoter GO:0006366 368 0.431
positive regulation of rna metabolic process GO:0051254 271 0.399
rhythmic behavior GO:0007622 76 0.395
circadian behavior GO:0048512 76 0.384
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.369
regulation of cell morphogenesis GO:0022604 163 0.363
male courtship behavior veined wing generated song production GO:0045433 20 0.357
growth GO:0040007 359 0.345
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.344
negative regulation of nucleic acid templated transcription GO:1903507 240 0.337
positive regulation of response to stimulus GO:0048584 323 0.331
regulation of cell proliferation GO:0042127 163 0.330
adult behavior GO:0030534 137 0.326
cell motility GO:0048870 251 0.318
response to organic cyclic compound GO:0014070 89 0.314
positive regulation of transcription dna templated GO:0045893 266 0.281
regionalization GO:0003002 416 0.275
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.274
eye development GO:0001654 323 0.263
positive regulation of growth GO:0045927 75 0.260
secondary metabolic process GO:0019748 75 0.258
positive regulation of signaling GO:0023056 243 0.256
appendage morphogenesis GO:0035107 397 0.251
negative regulation of female receptivity GO:0007621 14 0.240
axon development GO:0061564 297 0.233
localization of cell GO:0051674 257 0.228
dendrite guidance GO:0070983 21 0.223
positive regulation of nervous system development GO:0051962 69 0.209
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.207
positive regulation of developmental growth GO:0048639 62 0.207
regulation of cell development GO:0060284 215 0.205
negative regulation of cellular metabolic process GO:0031324 382 0.204
response to radiation GO:0009314 155 0.202
axon choice point recognition GO:0016198 26 0.202
response to endogenous stimulus GO:0009719 119 0.198
brain development GO:0007420 120 0.193
Fly
response to mechanical stimulus GO:0009612 28 0.193
regulation of cellular component biogenesis GO:0044087 201 0.193
positive regulation of developmental process GO:0051094 143 0.187
immune system process GO:0002376 347 0.187
dendrite morphogenesis GO:0048813 199 0.183
dendrite development GO:0016358 204 0.183
wing disc morphogenesis GO:0007472 344 0.182
response to alcohol GO:0097305 95 0.179
muscle organ development GO:0007517 127 0.172
cell type specific apoptotic process GO:0097285 38 0.171
synapse assembly GO:0007416 143 0.170
apoptotic process GO:0006915 159 0.157
catabolic process GO:0009056 409 0.148
immune response GO:0006955 246 0.146
response to gravity GO:0009629 26 0.143
negative regulation of biosynthetic process GO:0009890 277 0.143
cellular response to growth factor stimulus GO:0071363 30 0.142
forebrain development GO:0030900 2 0.141
energy taxis GO:0009453 21 0.139
cell migration GO:0016477 238 0.139
regulation of cell fate commitment GO:0010453 29 0.139
positive regulation of programmed cell death GO:0043068 62 0.138
regulation of behavior GO:0050795 75 0.138
response to extracellular stimulus GO:0009991 116 0.131
gland development GO:0048732 191 0.129
compound eye development GO:0048749 307 0.127
eye morphogenesis GO:0048592 260 0.118
neuromuscular junction development GO:0007528 149 0.109
cellular protein modification process GO:0006464 438 0.108
detection of stimulus involved in sensory perception GO:0050906 92 0.108
regulation of synapse structure and activity GO:0050803 128 0.108
mating behavior sex discrimination GO:0048047 7 0.105
imaginal disc derived wing morphogenesis GO:0007476 337 0.103
organic hydroxy compound metabolic process GO:1901615 83 0.101
inter male aggressive behavior GO:0002121 60 0.101
positive regulation of cell communication GO:0010647 250 0.099
phenol containing compound metabolic process GO:0018958 57 0.097
regulation of cell death GO:0010941 173 0.095
cognition GO:0050890 141 0.094
regulation of cell cycle GO:0051726 291 0.093
developmental growth involved in morphogenesis GO:0060560 65 0.088
regulation of localization GO:0032879 275 0.088
cellular response to organic substance GO:0071310 132 0.087
positive regulation of multicellular organismal process GO:0051240 143 0.087
circadian sleep wake cycle process GO:0022410 24 0.087
negative regulation of signal transduction GO:0009968 206 0.086
regulation of neuron differentiation GO:0045664 103 0.083
feeding behavior GO:0007631 50 0.083
copulation GO:0007620 26 0.083
response to bacterium GO:0009617 198 0.081
catecholamine biosynthetic process GO:0042423 3 0.081
camera type eye development GO:0043010 4 0.081
protein modification process GO:0036211 438 0.081
neuromuscular process GO:0050905 21 0.080
detection of stimulus GO:0051606 156 0.079
imaginal disc pattern formation GO:0007447 91 0.077
branching morphogenesis of an epithelial tube GO:0048754 45 0.077
response to growth factor GO:0070848 31 0.076
spermatid differentiation GO:0048515 114 0.076
morphogenesis of an epithelium GO:0002009 276 0.076
positive regulation of cellular component organization GO:0051130 156 0.075
programmed cell death GO:0012501 257 0.074
chromosome organization GO:0051276 360 0.074
death GO:0016265 284 0.074
cellular response to oxygen containing compound GO:1901701 79 0.073
cell death GO:0008219 279 0.070
organic substance catabolic process GO:1901575 308 0.069
establishment of planar polarity GO:0001736 87 0.068
intracellular receptor signaling pathway GO:0030522 19 0.068
positive regulation of signal transduction GO:0009967 223 0.067
rhythmic process GO:0048511 106 0.067
imaginal disc derived appendage development GO:0048737 399 0.067
enzyme linked receptor protein signaling pathway GO:0007167 179 0.067
epithelial cell migration GO:0010631 148 0.066
regulation of neurogenesis GO:0050767 158 0.063
digestive system development GO:0055123 149 0.062
leg disc morphogenesis GO:0007478 80 0.061
Fly
response to light stimulus GO:0009416 124 0.060
negative regulation of molecular function GO:0044092 51 0.060
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.059
dorsal ventral pattern formation GO:0009953 133 0.059
protein localization GO:0008104 284 0.059
melanization defense response GO:0035006 45 0.057
regulation of catalytic activity GO:0050790 185 0.057
respiratory system development GO:0060541 213 0.054
epithelial cell differentiation GO:0030855 322 0.053
memory GO:0007613 94 0.053
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.053
cellular response to endogenous stimulus GO:0071495 80 0.053
gravitaxis GO:0042332 26 0.053
convergent extension GO:0060026 2 0.052
protein complex biogenesis GO:0070271 201 0.052
regulation of response to external stimulus GO:0032101 115 0.052
response to nitrogen compound GO:1901698 90 0.052
axon guidance GO:0007411 233 0.051
organonitrogen compound metabolic process GO:1901564 318 0.051
tissue morphogenesis GO:0048729 297 0.050
response to ecdysone GO:0035075 34 0.050
positive regulation of cell proliferation GO:0008284 47 0.050
torso signaling pathway GO:0008293 21 0.049
protein maturation GO:0051604 71 0.049
regulation of immune system process GO:0002682 176 0.049
regulation of protein metabolic process GO:0051246 256 0.048
compound eye morphogenesis GO:0001745 249 0.048
male gamete generation GO:0048232 201 0.047
cell growth GO:0016049 108 0.047
regulation of apoptotic process GO:0042981 130 0.046
regulation of growth GO:0040008 233 0.046
response to biotic stimulus GO:0009607 294 0.046
organic acid metabolic process GO:0006082 103 0.046
actin filament organization GO:0007015 126 0.046
regulation of programmed cell death GO:0043067 152 0.046
long term memory GO:0007616 62 0.045
axis specification GO:0009798 167 0.045
regulation of synaptic transmission GO:0050804 69 0.043
establishment or maintenance of cell polarity GO:0007163 167 0.043
sensory perception of chemical stimulus GO:0007606 116 0.043
circulatory system development GO:0072359 82 0.043
organ growth GO:0035265 56 0.042
cellular response to organonitrogen compound GO:0071417 36 0.042
detection of abiotic stimulus GO:0009582 66 0.040
regulation of cellular protein metabolic process GO:0032268 243 0.039
amine metabolic process GO:0009308 12 0.039
spermatogenesis GO:0007283 200 0.039
single organism biosynthetic process GO:0044711 206 0.039
photoreceptor cell fate commitment GO:0046552 41 0.038
response to sterol GO:0036314 34 0.038
developmental programmed cell death GO:0010623 138 0.038
morphogenesis of a branching epithelium GO:0061138 45 0.037
regulation of embryonic development GO:0045995 68 0.037
phototaxis GO:0042331 21 0.037
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
sperm storage GO:0046693 10 0.036
neuron fate commitment GO:0048663 50 0.036
immune effector process GO:0002252 98 0.035
regulation of molecular function GO:0065009 217 0.034
regulation of phosphatase activity GO:0010921 3 0.033
startle response GO:0001964 16 0.033
cellular catabolic process GO:0044248 372 0.033
positive regulation of apoptotic process GO:0043065 47 0.033
open tracheal system development GO:0007424 204 0.033
dna dependent dna replication GO:0006261 17 0.033
positive regulation of intracellular signal transduction GO:1902533 116 0.032
wound healing spreading of epidermal cells GO:0035313 1 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
determination of bilateral symmetry GO:0009855 13 0.032
segmentation GO:0035282 207 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.032
regulation of phosphate metabolic process GO:0019220 210 0.031
cellular response to external stimulus GO:0071496 66 0.031
cell maturation GO:0048469 144 0.031
sleep GO:0030431 49 0.031
vesicle mediated transport GO:0016192 381 0.031
regulation of cellular response to growth factor stimulus GO:0090287 13 0.030
regulation of synapse organization GO:0050807 110 0.029
response to ketone GO:1901654 34 0.029
anterior posterior axis specification GO:0009948 109 0.029
embryonic axis specification GO:0000578 107 0.029
regulation of circadian sleep wake cycle GO:0042749 25 0.028
learning GO:0007612 75 0.028
response to nutrient levels GO:0031667 114 0.028
positive regulation of cell development GO:0010720 61 0.028
cell division GO:0051301 248 0.028
ameboidal type cell migration GO:0001667 151 0.027
regulation of synapse assembly GO:0051963 94 0.027
compound eye photoreceptor fate commitment GO:0001752 36 0.026
histolysis GO:0007559 102 0.026
positive regulation of cell differentiation GO:0045597 64 0.026
dopamine biosynthetic process GO:0042416 3 0.026
endocytosis GO:0006897 310 0.026
catechol containing compound biosynthetic process GO:0009713 3 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
response to wounding GO:0009611 94 0.025
regulation of cellular component movement GO:0051270 42 0.025
positive regulation of cellular component biogenesis GO:0044089 80 0.025
macromolecule catabolic process GO:0009057 161 0.025
imaginal disc derived leg morphogenesis GO:0007480 80 0.025
Fly
response to other organism GO:0051707 293 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
larval behavior GO:0030537 42 0.025
detection of external stimulus GO:0009581 66 0.024
neuron remodeling GO:0016322 29 0.024
embryonic pattern specification GO:0009880 174 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
anterior posterior axis specification embryo GO:0008595 103 0.024
synapse organization GO:0050808 196 0.024
molting cycle chitin based cuticle GO:0007591 56 0.024
appendage segmentation GO:0035285 26 0.023
insemination GO:0007320 22 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
regulation of cell projection organization GO:0031344 92 0.023
response to inorganic substance GO:0010035 44 0.023
regulation of response to stress GO:0080134 200 0.023
response to external biotic stimulus GO:0043207 293 0.023
positive regulation of immune system process GO:0002684 68 0.023
oviposition GO:0018991 19 0.023
tube development GO:0035295 244 0.022
proteolysis GO:0006508 192 0.022
neuron projection guidance GO:0097485 241 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
leg disc development GO:0035218 92 0.022
Fly
response to oxidative stress GO:0006979 86 0.022
regulation of locomotion GO:0040012 42 0.022
regulation of protein modification process GO:0031399 112 0.022
cardiovascular system development GO:0072358 82 0.022
blastoderm segmentation GO:0007350 159 0.021
positive regulation of molecular function GO:0044093 136 0.021
synaptic transmission GO:0007268 288 0.021
larval development GO:0002164 104 0.021
imaginal disc derived leg segmentation GO:0036011 26 0.021
chemotaxis GO:0006935 249 0.021
mrna metabolic process GO:0016071 124 0.021
neuron maturation GO:0042551 31 0.021
wnt signaling pathway GO:0016055 98 0.020
terminal region determination GO:0007362 25 0.020
purine containing compound metabolic process GO:0072521 155 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
positive regulation of cell death GO:0010942 69 0.019
synaptic growth at neuromuscular junction GO:0051124 119 0.019
response to axon injury GO:0048678 12 0.019
cellular response to extracellular stimulus GO:0031668 64 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
sensory organ morphogenesis GO:0090596 260 0.019
specification of symmetry GO:0009799 13 0.019
anatomical structure homeostasis GO:0060249 97 0.019
regulation of photoreceptor cell differentiation GO:0046532 34 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
epithelial tube morphogenesis GO:0060562 88 0.017
telencephalon development GO:0021537 2 0.017
tissue death GO:0016271 102 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
regulation of apoptotic signaling pathway GO:2001233 10 0.017
epithelial cell development GO:0002064 274 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
kidney epithelium development GO:0072073 3 0.016
molting cycle GO:0042303 56 0.016
appendage development GO:0048736 401 0.016
multicellular organismal aging GO:0010259 140 0.016
apoptotic signaling pathway GO:0097190 27 0.016
establishment of localization in cell GO:0051649 402 0.016
anterior posterior pattern specification GO:0009952 136 0.015
sex differentiation GO:0007548 81 0.015
Fly
primary amino compound biosynthetic process GO:1901162 2 0.015
eye photoreceptor cell fate commitment GO:0042706 37 0.015
dna metabolic process GO:0006259 227 0.015
positive regulation of execution phase of apoptosis GO:1900119 4 0.015
tripartite regional subdivision GO:0007351 103 0.015
female sex differentiation GO:0046660 20 0.015
Fly
gene silencing GO:0016458 138 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.014
regulation of organ growth GO:0046620 42 0.014
morphogenesis of a branching structure GO:0001763 45 0.014
ovarian follicle cell migration GO:0007297 121 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
apoptotic process involved in development GO:1902742 20 0.014
extracellular matrix organization GO:0030198 32 0.014
organic substance transport GO:0071702 257 0.014
positive regulation of synapse assembly GO:0051965 29 0.014
smoothened signaling pathway GO:0007224 49 0.014
oxoacid metabolic process GO:0043436 103 0.013
small molecule metabolic process GO:0044281 305 0.013
retina development in camera type eye GO:0060041 4 0.013
nephron tubule morphogenesis GO:0072078 3 0.013
positive regulation of locomotion GO:0040017 8 0.013
response to lipid GO:0033993 38 0.013
negative regulation of cell death GO:0060548 81 0.013
neuropeptide signaling pathway GO:0007218 45 0.013
regulation of cell growth GO:0001558 43 0.013
regulation of cell cycle process GO:0010564 181 0.013
nephron tubule development GO:0072080 3 0.013
regulation of transport GO:0051049 181 0.013
regulation of circadian rhythm GO:0042752 49 0.013
developmental maturation GO:0021700 172 0.013
salivary gland histolysis GO:0035070 88 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
anesthesia resistant memory GO:0007615 6 0.012
cuticle development GO:0042335 86 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
neuron projection extension GO:1990138 32 0.012
nitrogen compound transport GO:0071705 85 0.012
regulation of cell fate specification GO:0042659 27 0.012
thermosensory behavior GO:0040040 19 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
homeostatic process GO:0042592 199 0.011
response to alkaloid GO:0043279 26 0.011
regulation of organelle organization GO:0033043 196 0.011
determination of left right symmetry GO:0007368 9 0.011
response to toxic substance GO:0009636 22 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 3 0.011
connective tissue development GO:0061448 3 0.011
regulation of compound eye cone cell fate specification GO:0042682 4 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
genitalia development GO:0048806 26 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
nephron epithelium morphogenesis GO:0072088 3 0.011
alpha amino acid metabolic process GO:1901605 20 0.011
actin cytoskeleton organization GO:0030036 206 0.011
camera type eye morphogenesis GO:0048593 2 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
flight behavior GO:0007629 26 0.010
establishment of tissue polarity GO:0007164 87 0.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
response to hypoxia GO:0001666 53 0.010
regulation of female receptivity post mating GO:0046008 17 0.010
limb development GO:0060173 1 0.010
regulation of proteolysis GO:0030162 87 0.010
regulation of neuron projection development GO:0010975 69 0.010
rna processing GO:0006396 147 0.010
limb morphogenesis GO:0035108 1 0.010
g protein coupled receptor signaling pathway GO:0007186 136 0.010

fru disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
nervous system disease DOID:863 0 0.015