Drosophila melanogaster

57 known processes

fln (Dmel_CG7445)

flightin

(Aliases: Fln,CG7445,Ftn,mp27,Dmel\CG7445)

fln biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sarcomere organization GO:0045214 26 0.929
adult somatic muscle development GO:0007527 14 0.721
actomyosin structure organization GO:0031032 56 0.579
myofibril assembly GO:0030239 36 0.515
somatic muscle development GO:0007525 66 0.491
adult locomotory behavior GO:0008344 76 0.455
muscle structure development GO:0061061 224 0.426
glycerol 3 phosphate metabolic process GO:0006072 2 0.421
striated muscle cell differentiation GO:0051146 90 0.401
striated muscle cell development GO:0055002 50 0.395
adult behavior GO:0030534 137 0.372
protein complex assembly GO:0006461 200 0.322
muscle cell development GO:0055001 50 0.263
muscle cell differentiation GO:0042692 103 0.263
organelle assembly GO:0070925 198 0.230
cellular component assembly involved in morphogenesis GO:0010927 151 0.214
locomotory behavior GO:0007626 176 0.211
muscle organ development GO:0007517 127 0.197
actin cytoskeleton organization GO:0030036 206 0.193
striated muscle myosin thick filament assembly GO:0071688 3 0.170
body morphogenesis GO:0010171 2 0.159
muscle thin filament assembly GO:0071689 5 0.147
ribonucleoside catabolic process GO:0042454 112 0.133
cardiovascular system development GO:0072358 82 0.121
alditol phosphate metabolic process GO:0052646 2 0.105
actin filament based process GO:0030029 220 0.103
purine ribonucleoside metabolic process GO:0046128 127 0.103
single organism behavior GO:0044708 391 0.102
regulation of actin filament depolymerization GO:0030834 3 0.091
vesicle mediated transport GO:0016192 381 0.086
establishment of nucleus localization GO:0040023 26 0.080
flight behavior GO:0007629 26 0.071
organophosphate metabolic process GO:0019637 195 0.068
actin filament organization GO:0007015 126 0.065
skeletal muscle adaptation GO:0043501 1 0.062
intracellular signal transduction GO:0035556 300 0.060
muscle tissue morphogenesis GO:0060415 2 0.059
reactive oxygen species metabolic process GO:0072593 22 0.056
positive regulation of catabolic process GO:0009896 105 0.056
rhabdomere development GO:0042052 38 0.055
regulation of catabolic process GO:0009894 170 0.053
nucleobase containing small molecule metabolic process GO:0055086 174 0.051
nucleus localization GO:0051647 34 0.050
regulation of actin filament length GO:0030832 27 0.050
heart process GO:0003015 37 0.048
eye development GO:0001654 323 0.047
nucleoside triphosphate catabolic process GO:0009143 108 0.047
glycosyl compound catabolic process GO:1901658 112 0.047
camera type eye development GO:0043010 4 0.047
positive regulation of catalytic activity GO:0043085 118 0.045
skin development GO:0043588 65 0.044
formation of anatomical boundary GO:0048859 37 0.041
striated muscle adaptation GO:0014888 1 0.041
purine nucleoside triphosphate metabolic process GO:0009144 119 0.040
carbohydrate derivative catabolic process GO:1901136 118 0.040
single organism biosynthetic process GO:0044711 206 0.039
regulation of cellular catabolic process GO:0031329 157 0.039
respiratory system development GO:0060541 213 0.039
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
appendage development GO:0048736 401 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.037
regulation of phosphate metabolic process GO:0019220 210 0.036
purine nucleotide metabolic process GO:0006163 146 0.036
imaginal disc derived appendage development GO:0048737 399 0.035
carbohydrate biosynthetic process GO:0016051 17 0.035
ribonucleoside triphosphate metabolic process GO:0009199 119 0.035
nucleoside triphosphate metabolic process GO:0009141 120 0.034
cellular catabolic process GO:0044248 372 0.034
endocytosis GO:0006897 310 0.033
organic substance catabolic process GO:1901575 308 0.033
mitotic cytokinesis GO:0000281 50 0.033
carbohydrate derivative metabolic process GO:1901135 217 0.032
regulation of apoptotic process GO:0042981 130 0.031
homeostatic process GO:0042592 199 0.031
carbohydrate metabolic process GO:0005975 82 0.030
cellular macromolecular complex assembly GO:0034622 153 0.030
purine containing compound metabolic process GO:0072521 155 0.030
circulatory system development GO:0072359 82 0.030
developmental maturation GO:0021700 172 0.030
glycosyl compound metabolic process GO:1901657 127 0.029
programmed cell death GO:0012501 257 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
nucleotide catabolic process GO:0009166 109 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
organonitrogen compound metabolic process GO:1901564 318 0.027
single organism carbohydrate metabolic process GO:0044723 72 0.026
purine nucleotide catabolic process GO:0006195 109 0.026
aromatic compound catabolic process GO:0019439 166 0.026
mesenchymal cell differentiation GO:0048762 1 0.025
axon development GO:0061564 297 0.024
single organism intracellular transport GO:1902582 207 0.024
electron transport chain GO:0022900 14 0.024
lipid metabolic process GO:0006629 121 0.024
organelle fission GO:0048285 340 0.024
cation homeostasis GO:0055080 51 0.024
energy derivation by oxidation of organic compounds GO:0015980 32 0.024
oxidation reduction process GO:0055114 123 0.024
regulation of hydrolase activity GO:0051336 97 0.023
actin filament based movement GO:0030048 26 0.023
cellular respiration GO:0045333 26 0.023
cell division GO:0051301 248 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
glutathione metabolic process GO:0006749 37 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
response to oxygen levels GO:0070482 59 0.023
phagocytosis GO:0006909 215 0.023
gastrulation GO:0007369 70 0.023
immune system process GO:0002376 347 0.022
purine containing compound catabolic process GO:0072523 112 0.022
positive regulation of molecular function GO:0044093 136 0.022
phosphorylation GO:0016310 294 0.022
cellular protein complex disassembly GO:0043624 35 0.022
purine nucleoside catabolic process GO:0006152 112 0.022
small molecule metabolic process GO:0044281 305 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
regulation of protein complex disassembly GO:0043244 29 0.022
neuron recognition GO:0008038 101 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
growth GO:0040007 359 0.021
heterocycle catabolic process GO:0046700 166 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
mesoderm development GO:0007498 78 0.021
regulation of nucleotide catabolic process GO:0030811 48 0.021
apical constriction GO:0003383 18 0.020
regulation of blood circulation GO:1903522 21 0.020
kidney development GO:0001822 3 0.020
protein modification process GO:0036211 438 0.020
purine nucleoside metabolic process GO:0042278 127 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
regionalization GO:0003002 416 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
wing disc morphogenesis GO:0007472 344 0.020
anterior posterior pattern specification GO:0009952 136 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
mitotic nuclear division GO:0007067 213 0.019
cell migration GO:0016477 238 0.019
regulation of catalytic activity GO:0050790 185 0.019
nucleoside metabolic process GO:0009116 127 0.019
establishment of localization in cell GO:0051649 402 0.019
regulation of cell differentiation GO:0045595 302 0.018
transmembrane transport GO:0055085 139 0.018
striated muscle tissue development GO:0014706 27 0.018
tube formation GO:0035148 21 0.018
negative regulation of synapse assembly GO:0051964 39 0.017
regulation of purine nucleotide catabolic process GO:0033121 48 0.017
organic substance transport GO:0071702 257 0.017
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
nucleoside catabolic process GO:0009164 112 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
imaginal disc derived wing hair organization GO:0035317 45 0.016
response to hexose GO:0009746 3 0.016
response to monosaccharide GO:0034284 4 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
cellular protein complex assembly GO:0043623 71 0.016
cell death GO:0008219 279 0.016
response to organophosphorus GO:0046683 2 0.016
compound eye development GO:0048749 307 0.016
cognition GO:0050890 141 0.016
cell recognition GO:0008037 102 0.016
nucleus organization GO:0006997 45 0.016
macromolecular complex assembly GO:0065003 256 0.016
intracellular transport GO:0046907 228 0.016
single organism catabolic process GO:0044712 228 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
negative regulation of actin filament depolymerization GO:0030835 2 0.015
epithelial cell differentiation GO:0030855 322 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
positive regulation of actin filament polymerization GO:0030838 11 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
regulation of gtp catabolic process GO:0033124 44 0.015
nucleotide metabolic process GO:0009117 161 0.015
response to abiotic stimulus GO:0009628 341 0.015
ovulation GO:0030728 4 0.015
regulation of protein depolymerization GO:1901879 27 0.015
mesenchymal cell development GO:0014031 1 0.015
spiracle morphogenesis open tracheal system GO:0035277 22 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
regulation of tube length open tracheal system GO:0035159 24 0.014
multi organism behavior GO:0051705 175 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
circulatory system process GO:0003013 37 0.014
nuclear division GO:0000280 332 0.014
ras protein signal transduction GO:0007265 88 0.014
negative regulation of molecular function GO:0044092 51 0.014
organic acid metabolic process GO:0006082 103 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
localization of cell GO:0051674 257 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
multicellular organism growth GO:0035264 46 0.013
blood circulation GO:0008015 26 0.013
cellular metal ion homeostasis GO:0006875 31 0.013
protein polymerization GO:0051258 42 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
larval development GO:0002164 104 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
embryonic pattern specification GO:0009880 174 0.013
embryonic morphogenesis GO:0048598 206 0.013
gtp catabolic process GO:0006184 72 0.013
muscle attachment GO:0016203 36 0.013
cardiac muscle tissue development GO:0048738 9 0.012
connective tissue development GO:0061448 3 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
multi organism reproductive behavior GO:0044705 121 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
negative regulation of phosphorus metabolic process GO:0010563 45 0.012
open tracheal system development GO:0007424 204 0.012
response to wounding GO:0009611 94 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
compound eye morphogenesis GO:0001745 249 0.012
androgen metabolic process GO:0008209 1 0.012
monosaccharide metabolic process GO:0005996 9 0.012
catabolic process GO:0009056 409 0.011
larval somatic muscle development GO:0007526 19 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of protein complex assembly GO:0043254 42 0.011
positive regulation of signal transduction GO:0009967 223 0.011
muscle adaptation GO:0043500 1 0.011
neurological system process GO:0050877 358 0.011
mitochondrion organization GO:0007005 65 0.011
regulation of cell proliferation GO:0042127 163 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
nuclear migration GO:0007097 20 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.011
heart contraction GO:0060047 26 0.011
chemical homeostasis GO:0048878 92 0.011
death GO:0016265 284 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
membrane depolarization GO:0051899 4 0.011
cellular response to ethanol GO:0071361 4 0.011
maintenance of location GO:0051235 73 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
cellular response to oxygen levels GO:0071453 30 0.010
cardiac muscle cell differentiation GO:0055007 4 0.010
regulation of organelle organization GO:0033043 196 0.010
nicotinamide nucleotide metabolic process GO:0046496 2 0.010
response to other organism GO:0051707 293 0.010
regulation of transport GO:0051049 181 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
regulation of localization GO:0032879 275 0.010
negative regulation of actin filament polymerization GO:0030837 7 0.010
cellular protein modification process GO:0006464 438 0.010
cellular amino acid metabolic process GO:0006520 61 0.010

fln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.041
muscular disease DOID:0080000 0 0.041
heart disease DOID:114 0 0.041
cardiomyopathy DOID:0050700 0 0.041
dilated cardiomyopathy DOID:12930 0 0.041
disease of anatomical entity DOID:7 0 0.041
intrinsic cardiomyopathy DOID:0060036 0 0.041
cardiovascular system disease DOID:1287 0 0.041
musculoskeletal system disease DOID:17 0 0.041
muscle tissue disease DOID:66 0 0.041
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.016
neurodegenerative disease DOID:1289 0 0.016
parkinson s disease DOID:14330 0 0.015
synucleinopathy DOID:0050890 0 0.015