Drosophila melanogaster

123 known processes

lin19 (Dmel_CG1877)

lin-19-like

(Aliases: Dmel\CG1877,cul-1,lin-19/cul-1,CUL1,cul1,lin19-like,dCul-1,Cullin1,l(2)k01207,l(2)02074,dCul1,Cul-1,Cul1,CG1877)

lin19 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of intracellular signal transduction GO:1902531 236 0.941
protein ubiquitination GO:0016567 70 0.939
Human Mouse
protein modification by small protein conjugation or removal GO:0070647 106 0.857
Human Mouse
axonogenesis GO:0007409 290 0.839
mitotic cell cycle phase transition GO:0044772 138 0.810
protein modification by small protein conjugation GO:0032446 79 0.809
Human Mouse
protein modification process GO:0036211 438 0.768
Human Mouse
growth GO:0040007 359 0.763
Worm
catabolic process GO:0009056 409 0.682
protein localization GO:0008104 284 0.660
regulation of cell cycle phase transition GO:1901987 130 0.637
cellular protein modification process GO:0006464 438 0.598
Human Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.586
axon guidance GO:0007411 233 0.584
reproductive behavior GO:0019098 122 0.550
neuron remodeling GO:0016322 29 0.544
cellular response to dna damage stimulus GO:0006974 223 0.530
mitotic dna integrity checkpoint GO:0044774 75 0.522
axon development GO:0061564 297 0.508
regulation of cellular component biogenesis GO:0044087 201 0.498
response to organic substance GO:0010033 284 0.484
dendrite development GO:0016358 204 0.483
mitotic g2 m transition checkpoint GO:0044818 70 0.459
mitotic dna damage checkpoint GO:0044773 74 0.458
nucleobase containing compound catabolic process GO:0034655 165 0.442
regulation of cellular protein metabolic process GO:0032268 243 0.436
cell cycle phase transition GO:0044770 140 0.430
cell cycle checkpoint GO:0000075 95 0.427
negative regulation of developmental process GO:0051093 201 0.400
embryo development ending in birth or egg hatching GO:0009792 152 0.396
Worm
cellular catabolic process GO:0044248 372 0.387
Human Mouse
body morphogenesis GO:0010171 2 0.380
regulation of mitotic cell cycle phase transition GO:1901990 130 0.374
regulation of nervous system development GO:0051960 248 0.354
intracellular signal transduction GO:0035556 300 0.347
ubiquitin dependent protein catabolic process GO:0006511 78 0.337
Human Mouse
aromatic compound catabolic process GO:0019439 166 0.327
multi organism reproductive behavior GO:0044705 121 0.317
modification dependent protein catabolic process GO:0019941 78 0.317
Human Mouse
negative regulation of neural precursor cell proliferation GO:2000178 27 0.314
regulation of cellular catabolic process GO:0031329 157 0.288
negative regulation of neuroblast proliferation GO:0007406 27 0.285
ribonucleotide metabolic process GO:0009259 145 0.278
taxis GO:0042330 304 0.269
proteasomal protein catabolic process GO:0010498 59 0.265
Human Mouse
regulation of molecular function GO:0065009 217 0.265
modification dependent macromolecule catabolic process GO:0043632 79 0.250
Human Mouse
regulation of multicellular organismal development GO:2000026 414 0.247
neuron projection guidance GO:0097485 241 0.245
response to biotic stimulus GO:0009607 294 0.241
Worm
developmental growth GO:0048589 280 0.238
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.236
Human Mouse
organic substance catabolic process GO:1901575 308 0.230
synapse organization GO:0050808 196 0.224
phosphorylation GO:0016310 294 0.209
small molecule metabolic process GO:0044281 305 0.208
protein catabolic process GO:0030163 101 0.207
programmed cell death GO:0012501 257 0.201
apoptotic process GO:0006915 159 0.201
negative regulation of nervous system development GO:0051961 92 0.193
establishment of localization in cell GO:0051649 402 0.190
regulation of catabolic process GO:0009894 170 0.180
regulation of cell development GO:0060284 215 0.180
endocytosis GO:0006897 310 0.174
Worm
regulation of response to stress GO:0080134 200 0.173
positive regulation of cellular biosynthetic process GO:0031328 316 0.170
positive regulation of cellular component organization GO:0051130 156 0.164
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.158
cellular protein catabolic process GO:0044257 83 0.157
Human Mouse
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.157
Human Mouse
regulation of growth GO:0040008 233 0.153
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.151
negative regulation of multicellular organismal process GO:0051241 142 0.148
positive regulation of protein metabolic process GO:0051247 128 0.148
regulation of cellular amine metabolic process GO:0033238 3 0.148
regulation of cell cycle process GO:0010564 181 0.148
dna integrity checkpoint GO:0031570 81 0.147
organic cyclic compound catabolic process GO:1901361 168 0.143
lateral inhibition GO:0046331 206 0.141
regulation of phosphorus metabolic process GO:0051174 210 0.139
negative regulation of signaling GO:0023057 219 0.138
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.133
Human Mouse
ribonucleoside catabolic process GO:0042454 112 0.132
regulation of cell differentiation GO:0045595 302 0.130
defense response to other organism GO:0098542 225 0.127
Worm
regulation of cell morphogenesis GO:0022604 163 0.127
cellular nitrogen compound catabolic process GO:0044270 165 0.126
posttranscriptional regulation of gene expression GO:0010608 145 0.125
synapse assembly GO:0007416 143 0.125
ribonucleoside triphosphate metabolic process GO:0009199 119 0.124
regulation of anatomical structure morphogenesis GO:0022603 242 0.121
protein complex biogenesis GO:0070271 201 0.119
positive regulation of proteolysis GO:0045862 52 0.119
organic acid metabolic process GO:0006082 103 0.116
maintenance of location GO:0051235 73 0.110
organophosphate metabolic process GO:0019637 195 0.109
positive regulation of macromolecule metabolic process GO:0010604 405 0.108
cellular macromolecule catabolic process GO:0044265 136 0.107
Human Mouse
nuclear division GO:0000280 332 0.105
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.104
regulation of organelle organization GO:0033043 196 0.102
lipid localization GO:0010876 54 0.102
amine metabolic process GO:0009308 12 0.100
oxoacid metabolic process GO:0043436 103 0.100
neurological system process GO:0050877 358 0.099
regulation of translation GO:0006417 56 0.099
macromolecule catabolic process GO:0009057 161 0.098
photoreceptor cell differentiation GO:0046530 170 0.097
multi multicellular organism process GO:0044706 123 0.095
purine nucleoside metabolic process GO:0042278 127 0.093
positive regulation of signal transduction GO:0009967 223 0.092
purine ribonucleotide metabolic process GO:0009150 145 0.092
macromolecular complex assembly GO:0065003 256 0.091
synaptic growth at neuromuscular junction GO:0051124 119 0.086
proteolysis GO:0006508 192 0.083
Human Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.083
ribonucleotide catabolic process GO:0009261 109 0.082
nucleoside phosphate metabolic process GO:0006753 162 0.081
multicellular organismal aging GO:0010259 140 0.079
Worm
negative regulation of stem cell proliferation GO:2000647 30 0.078
larval midgut histolysis GO:0035069 22 0.076
cell proliferation GO:0008283 299 0.076
Mouse Worm
negative regulation of growth GO:0045926 84 0.076
organonitrogen compound catabolic process GO:1901565 128 0.076
organophosphate catabolic process GO:0046434 112 0.075
glycosyl compound catabolic process GO:1901658 112 0.074
intracellular transport GO:0046907 228 0.072
regulation of endopeptidase activity GO:0052548 36 0.072
regulation of protein modification process GO:0031399 112 0.069
purine containing compound catabolic process GO:0072523 112 0.068
necrotic cell death GO:0070265 1 0.068
regulation of neurogenesis GO:0050767 158 0.067
regulation of developmental growth GO:0048638 174 0.066
cell cell signaling involved in cell fate commitment GO:0045168 210 0.065
regulation of phosphate metabolic process GO:0019220 210 0.064
meiotic nuclear division GO:0007126 151 0.064
organic substance transport GO:0071702 257 0.063
heterocycle catabolic process GO:0046700 166 0.062
cellularization GO:0007349 90 0.060
establishment of protein localization GO:0045184 163 0.059
regulation of cell cycle GO:0051726 291 0.059
histone h2a ubiquitination GO:0033522 2 0.058
oviposition GO:0018991 19 0.057
response to wounding GO:0009611 94 0.057
positive regulation of cellular catabolic process GO:0031331 95 0.056
response to virus GO:0009615 28 0.056
Worm
positive regulation of developmental growth GO:0048639 62 0.055
nucleotide metabolic process GO:0009117 161 0.054
positive regulation of nucleic acid templated transcription GO:1903508 266 0.053
purine containing compound metabolic process GO:0072521 155 0.053
nucleoside triphosphate metabolic process GO:0009141 120 0.052
dephosphorylation GO:0016311 51 0.051
tube morphogenesis GO:0035239 191 0.051
negative regulation of cell communication GO:0010648 223 0.051
single organism intracellular transport GO:1902582 207 0.051
negative regulation of cell differentiation GO:0045596 143 0.050
eye morphogenesis GO:0048592 260 0.050
nucleoside phosphate catabolic process GO:1901292 110 0.049
nucleobase containing small molecule metabolic process GO:0055086 174 0.048
regulation of nurse cell apoptotic process GO:0045477 9 0.048
innate immune response GO:0045087 144 0.047
regulation of multi organism process GO:0043900 131 0.047
nf kappab import into nucleus GO:0042348 1 0.047
cell maturation GO:0048469 144 0.046
organelle fission GO:0048285 340 0.046
Worm
regulation of cell growth GO:0001558 43 0.046
regulation of neural precursor cell proliferation GO:2000177 35 0.045
gene silencing by rna GO:0031047 57 0.045
negative regulation of cellular component organization GO:0051129 108 0.045
regulation of catalytic activity GO:0050790 185 0.044
chemotaxis GO:0006935 249 0.044
positive regulation of molecular function GO:0044093 136 0.044
lipid storage GO:0019915 38 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
negative regulation of mitotic cell cycle GO:0045930 109 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.042
protein acylation GO:0043543 42 0.042
negative regulation of cell proliferation GO:0008285 69 0.042
Worm
guanosine containing compound catabolic process GO:1901069 74 0.041
ribose phosphate metabolic process GO:0019693 145 0.041
regulation of nucleotide metabolic process GO:0006140 62 0.040
positive regulation of peptidase activity GO:0010952 29 0.039
negative regulation of neurogenesis GO:0050768 53 0.039
regulation of cell death GO:0010941 173 0.038
mitotic nuclear division GO:0007067 213 0.037
Worm
negative regulation of developmental growth GO:0048640 64 0.037
regulation of mitotic cell cycle GO:0007346 190 0.036
tissue death GO:0016271 102 0.036
positive regulation of response to stimulus GO:0048584 323 0.036
negative regulation of intracellular signal transduction GO:1902532 57 0.035
translation GO:0006412 69 0.034
compound eye photoreceptor cell differentiation GO:0001751 140 0.034
positive regulation of catabolic process GO:0009896 105 0.034
protein phosphorylation GO:0006468 169 0.033
response to dsrna GO:0043331 15 0.032
protein polyubiquitination GO:0000209 11 0.032
cell growth GO:0016049 108 0.032
ovarian follicle cell development GO:0030707 248 0.031
mitotic g2 dna damage checkpoint GO:0007095 69 0.031
single organism catabolic process GO:0044712 228 0.031
regulation of cell shape GO:0008360 113 0.031
morphogenesis of a branching structure GO:0001763 45 0.031
purine nucleoside catabolic process GO:0006152 112 0.030
regulation of cell proliferation GO:0042127 163 0.030
Worm
positive regulation of gene expression GO:0010628 290 0.030
regulation of cellular response to stress GO:0080135 89 0.030
organic hydroxy compound metabolic process GO:1901615 83 0.029
response to external biotic stimulus GO:0043207 293 0.029
Worm
production of molecular mediator of immune response GO:0002440 46 0.028
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.028
protein complex assembly GO:0006461 200 0.028
regulation of actin cytoskeleton organization GO:0032956 42 0.028
protein transport GO:0015031 155 0.028
cellular response to carbohydrate stimulus GO:0071322 4 0.028
vesicle organization GO:0016050 44 0.028
establishment or maintenance of cell polarity GO:0007163 167 0.027
axon midline choice point recognition GO:0016199 26 0.027
response to other organism GO:0051707 293 0.026
Worm
regulation of ras protein signal transduction GO:0046578 93 0.026
response to nitrogen compound GO:1901698 90 0.026
regulation of protein localization to nucleus GO:1900180 29 0.026
columnar cuboidal epithelial cell development GO:0002066 249 0.025
cell death GO:0008219 279 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.025
cellular response to oxygen containing compound GO:1901701 79 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
regulation of stem cell proliferation GO:0072091 40 0.024
cellular protein localization GO:0034613 160 0.024
posttranscriptional gene silencing by rna GO:0035194 45 0.024
larval development GO:0002164 104 0.024
Worm
purine nucleotide catabolic process GO:0006195 109 0.024
peptidyl amino acid modification GO:0018193 105 0.024
cellular protein complex assembly GO:0043623 71 0.024
dendrite morphogenesis GO:0048813 199 0.024
cytoplasmic transport GO:0016482 130 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.023
peptide biosynthetic process GO:0043043 42 0.023
regulation of synapse assembly GO:0051963 94 0.023
cellular lipid metabolic process GO:0044255 83 0.023
neural precursor cell proliferation GO:0061351 75 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
homeostatic process GO:0042592 199 0.022
regulation of protein targeting GO:1903533 29 0.022
mitotic cell cycle checkpoint GO:0007093 88 0.022
compound eye morphogenesis GO:0001745 249 0.022
stem cell development GO:0048864 79 0.022
regulation of hemocyte proliferation GO:0035206 37 0.022
regulation of cellular component size GO:0032535 98 0.022
Worm
mesenchymal cell differentiation GO:0048762 1 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
Worm
regulation of synapse organization GO:0050807 110 0.021
g2 dna damage checkpoint GO:0031572 69 0.021
respiratory system development GO:0060541 213 0.021
nucleoside catabolic process GO:0009164 112 0.021
chromatin assembly or disassembly GO:0006333 52 0.020
response to abiotic stimulus GO:0009628 341 0.020
regulation of synapse structure and activity GO:0050803 128 0.020
cognition GO:0050890 141 0.020
male gamete generation GO:0048232 201 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
eye photoreceptor cell development GO:0042462 81 0.020
larval midgut cell programmed cell death GO:0035096 19 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
nucleoside metabolic process GO:0009116 127 0.019
cellular amine metabolic process GO:0044106 12 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
carboxylic acid metabolic process GO:0019752 92 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
regulation of axonogenesis GO:0050770 32 0.018
positive regulation of mitotic cell cycle GO:0045931 34 0.018
endomembrane system organization GO:0010256 119 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
lipid metabolic process GO:0006629 121 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
cardiovascular system development GO:0072358 82 0.018
determination of dorsal ventral asymmetry GO:0048262 3 0.018
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
purine ribonucleoside metabolic process GO:0046128 127 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
stem cell proliferation GO:0072089 88 0.018
regulation of localization GO:0032879 275 0.017
regulation of intracellular transport GO:0032386 64 0.017
regulation of cysteine type endopeptidase activity GO:2000116 27 0.017
regulation of protein stability GO:0031647 43 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
positive regulation of cell communication GO:0010647 250 0.017
meiotic cell cycle GO:0051321 171 0.017
positive regulation of apoptotic process GO:0043065 47 0.017
Worm
small gtpase mediated signal transduction GO:0007264 88 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
regulation of mapk cascade GO:0043408 92 0.017
vesicle mediated transport GO:0016192 381 0.017
Worm
regulation of purine nucleotide catabolic process GO:0033121 48 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
photoreceptor cell development GO:0042461 96 0.017
regulation of nucleotide catabolic process GO:0030811 48 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
dendrite guidance GO:0070983 21 0.016
regulation of neuroblast proliferation GO:1902692 34 0.016
phagocytosis GO:0006909 215 0.016
positive regulation of cell cycle GO:0045787 43 0.016
regulation of response to external stimulus GO:0032101 115 0.016
positive regulation of growth GO:0045927 75 0.016
death GO:0016265 284 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.015
stem cell differentiation GO:0048863 117 0.015
positive regulation of translation GO:0045727 12 0.015
regulation of programmed cell death GO:0043067 152 0.015
reproductive structure development GO:0048608 74 0.015
Worm
tissue morphogenesis GO:0048729 297 0.015
response to radiation GO:0009314 155 0.015
tube development GO:0035295 244 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
negative regulation of cell cycle phase transition GO:1901988 103 0.015
defense response GO:0006952 300 0.015
Worm
apoptotic signaling pathway GO:0097190 27 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.014
regulation of defense response to virus by host GO:0050691 10 0.014
regulation of protein metabolic process GO:0051246 256 0.014
immune response GO:0006955 246 0.014
histone ubiquitination GO:0016574 4 0.014
neuron maturation GO:0042551 31 0.014
negative regulation of cell development GO:0010721 62 0.014
multi organism behavior GO:0051705 175 0.014
mitotic spindle organization GO:0007052 220 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
regulation of immune effector process GO:0002697 52 0.013
dna damage checkpoint GO:0000077 78 0.013
chromosome organization GO:0051276 360 0.013
production of small rna involved in gene silencing by rna GO:0070918 15 0.013
nitrogen compound transport GO:0071705 85 0.013
glycerolipid metabolic process GO:0046486 34 0.013
sensory organ morphogenesis GO:0090596 260 0.013
regulation of phosphorylation GO:0042325 147 0.013
cell motility GO:0048870 251 0.012
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.012
mrna splice site selection GO:0006376 1 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
response to glucose GO:0009749 2 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
protein acetylation GO:0006473 39 0.012
atp catabolic process GO:0006200 38 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
regulation of hydrolase activity GO:0051336 97 0.012
compound eye photoreceptor development GO:0042051 78 0.012
regulation of neuron differentiation GO:0045664 103 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
spindle organization GO:0007051 253 0.011
regulation of response to gamma radiation GO:2001228 4 0.011
cellular ketone metabolic process GO:0042180 24 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of gtpase activity GO:0043087 44 0.011
ras protein signal transduction GO:0007265 88 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.010
histone h2a monoubiquitination GO:0035518 1 0.010
chromatin modification GO:0016568 147 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
cell migration GO:0016477 238 0.010
Worm
regulation of protein ubiquitination GO:0031396 22 0.010
execution phase of apoptosis GO:0097194 7 0.010
learning or memory GO:0007611 141 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.010
mapk cascade GO:0000165 107 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
regulation of apoptotic process GO:0042981 130 0.010
nucleosome assembly GO:0006334 35 0.010
forebrain development GO:0030900 2 0.010

lin19 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org