Drosophila melanogaster

115 known processes

Jafrac2 (Dmel_CG1274)

thioredoxin peroxidase 2

(Aliases: Dmel\CG1274,CG1274,1274,Jafrac-2,Prx4156,DPx4156,DPx-4156)

Jafrac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 257 0.183
oxidation reduction process GO:0055114 123 0.139
positive regulation of response to stimulus GO:0048584 323 0.135
developmental programmed cell death GO:0010623 138 0.100
regulation of catalytic activity GO:0050790 185 0.096
response to alcohol GO:0097305 95 0.091
intracellular signal transduction GO:0035556 300 0.088
autophagy GO:0006914 108 0.084
response to organic substance GO:0010033 284 0.077
response to oxygen radical GO:0000305 3 0.076
positive regulation of signaling GO:0023056 243 0.075
regulation of cell death GO:0010941 173 0.071
negative regulation of cellular metabolic process GO:0031324 382 0.070
appendage development GO:0048736 401 0.066
death GO:0016265 284 0.065
immune system process GO:0002376 347 0.062
dendrite morphogenesis GO:0048813 199 0.061
regulation of molecular function GO:0065009 217 0.061
regulation of immune system process GO:0002682 176 0.060
regulation of multicellular organismal development GO:2000026 414 0.059
regulation of hydrolase activity GO:0051336 97 0.058
amine metabolic process GO:0009308 12 0.056
regulation of response to stress GO:0080134 200 0.056
cell death GO:0008219 279 0.050
response to biotic stimulus GO:0009607 294 0.050
response to oxygen containing compound GO:1901700 200 0.048
regulation of localization GO:0032879 275 0.048
gland development GO:0048732 191 0.047
positive regulation of molecular function GO:0044093 136 0.047
regulation of anatomical structure morphogenesis GO:0022603 242 0.046
purine containing compound metabolic process GO:0072521 155 0.045
secretion by cell GO:0032940 101 0.045
positive regulation of proteolysis GO:0045862 52 0.044
salivary gland cell autophagic cell death GO:0035071 83 0.044
response to other organism GO:0051707 293 0.043
salivary gland morphogenesis GO:0007435 145 0.042
locomotory behavior GO:0007626 176 0.041
growth GO:0040007 359 0.041
dendrite development GO:0016358 204 0.041
regulation of transport GO:0051049 181 0.041
tissue death GO:0016271 102 0.040
autophagic cell death GO:0048102 83 0.040
positive regulation of catalytic activity GO:0043085 118 0.040
positive regulation of signal transduction GO:0009967 223 0.038
response to radiation GO:0009314 155 0.038
apoptotic process GO:0006915 159 0.038
positive regulation of programmed cell death GO:0043068 62 0.037
negative regulation of molecular function GO:0044092 51 0.036
intrinsic apoptotic signaling pathway GO:0097193 16 0.036
positive regulation of cell communication GO:0010647 250 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
defense response GO:0006952 300 0.035
cation transport GO:0006812 110 0.034
cellular response to extracellular stimulus GO:0031668 64 0.034
Yeast
regulation of growth GO:0040008 233 0.034
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.034
protein modification process GO:0036211 438 0.032
positive regulation of apoptotic signaling pathway GO:2001235 4 0.032
protein complex assembly GO:0006461 200 0.032
exocrine system development GO:0035272 162 0.031
regulation of catabolic process GO:0009894 170 0.030
salivary gland development GO:0007431 162 0.030
cellular response to organic substance GO:0071310 132 0.029
regulation of endopeptidase activity GO:0052548 36 0.029
regulation of peptidase activity GO:0052547 39 0.029
salivary gland histolysis GO:0035070 88 0.029
regulation of programmed cell death GO:0043067 152 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
response to external biotic stimulus GO:0043207 293 0.028
sex differentiation GO:0007548 81 0.028
response to ethanol GO:0045471 59 0.027
cellular protein modification process GO:0006464 438 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
Fly
intracellular protein transport GO:0006886 104 0.026
cellular homeostasis GO:0019725 80 0.026
Yeast Fly
regulation of cellular catabolic process GO:0031329 157 0.026
regulation of anatomical structure size GO:0090066 163 0.026
regulation of multi organism process GO:0043900 131 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
muscle organ development GO:0007517 127 0.026
regulation of apoptotic process GO:0042981 130 0.026
cellular catabolic process GO:0044248 372 0.026
single organism cellular localization GO:1902580 180 0.026
regulation of cell differentiation GO:0045595 302 0.025
energy derivation by oxidation of organic compounds GO:0015980 32 0.025
gland morphogenesis GO:0022612 145 0.025
homeostatic process GO:0042592 199 0.025
Yeast Fly
regulation of autophagy GO:0010506 62 0.025
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.025
intracellular transport GO:0046907 228 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
histolysis GO:0007559 102 0.025
establishment of protein localization GO:0045184 163 0.024
cytoplasmic transport GO:0016482 130 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
organic substance transport GO:0071702 257 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
divalent inorganic cation homeostasis GO:0072507 29 0.023
protein transport GO:0015031 155 0.023
secretion GO:0046903 109 0.023
regulation of protein localization GO:0032880 76 0.023
purine ribonucleoside metabolic process GO:0046128 127 0.023
adult behavior GO:0030534 137 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
cellular amine metabolic process GO:0044106 12 0.023
multicellular organismal aging GO:0010259 140 0.023
Fly
response to abiotic stimulus GO:0009628 341 0.022
macromolecular complex assembly GO:0065003 256 0.022
cellular response to oxidative stress GO:0034599 28 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
synaptic transmission GO:0007268 288 0.022
transmembrane transport GO:0055085 139 0.022
appendage morphogenesis GO:0035107 397 0.022
imaginal disc derived appendage development GO:0048737 399 0.021
regulation of cellular localization GO:0060341 136 0.021
dna damage checkpoint GO:0000077 78 0.021
Yeast
regulation of protein transport GO:0051223 57 0.021
immune effector process GO:0002252 98 0.021
establishment of localization in cell GO:0051649 402 0.021
regulation of protein metabolic process GO:0051246 256 0.021
taxis GO:0042330 304 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
telencephalon development GO:0021537 2 0.020
immune response GO:0006955 246 0.020
developmental growth GO:0048589 280 0.020
response to superoxide GO:0000303 3 0.019
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
positive regulation of gene expression GO:0010628 290 0.019
negative regulation of cell communication GO:0010648 223 0.019
negative regulation of response to stimulus GO:0048585 258 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
response to oxidative stress GO:0006979 86 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
sensory organ morphogenesis GO:0090596 260 0.018
determination of adult lifespan GO:0008340 137 0.018
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
positive regulation of cell death GO:0010942 69 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
regulation of proteolysis GO:0030162 87 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
nuclear division GO:0000280 332 0.017
carbohydrate metabolic process GO:0005975 82 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
brain development GO:0007420 120 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
forebrain development GO:0030900 2 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
single organism membrane organization GO:0044802 93 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.015
cell division GO:0051301 248 0.015
membrane organization GO:0061024 112 0.015
humoral immune response GO:0006959 117 0.015
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.015
regulation of cellular response to oxidative stress GO:1900407 4 0.015
immune system development GO:0002520 57 0.015
negative regulation of cell death GO:0060548 81 0.015
Fly
mushroom body development GO:0016319 70 0.015
immune response activating signal transduction GO:0002757 2 0.015
phenol containing compound metabolic process GO:0018958 57 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
protein processing GO:0016485 68 0.015
cellular response to external stimulus GO:0071496 66 0.015
Yeast
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.014
vesicle mediated transport GO:0016192 381 0.014
Fly
neurological system process GO:0050877 358 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of innate immune response GO:0045088 71 0.014
catabolic process GO:0009056 409 0.014
protein localization GO:0008104 284 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
positive regulation of cell motility GO:2000147 3 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
protein maturation GO:0051604 71 0.014
negative regulation of signaling GO:0023057 219 0.014
nucleotide metabolic process GO:0009117 161 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
cellular amide metabolic process GO:0043603 80 0.014
single organism intracellular transport GO:1902582 207 0.014
positive regulation of developmental process GO:0051094 143 0.014
regulation of organelle organization GO:0033043 196 0.014
cellular biogenic amine catabolic process GO:0042402 1 0.013
defense response to bacterium GO:0042742 178 0.013
single organism biosynthetic process GO:0044711 206 0.013
regulation of immune response GO:0050776 118 0.013
actin filament organization GO:0007015 126 0.013
positive regulation of transport GO:0051050 92 0.013
wing disc morphogenesis GO:0007472 344 0.013
regulation of developmental growth GO:0048638 174 0.013
single organism behavior GO:0044708 391 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
ion transport GO:0006811 145 0.012
peptidyl amino acid modification GO:0018193 105 0.012
wnt signaling pathway GO:0016055 98 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
phagocytosis GO:0006909 215 0.012
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cellular response to starvation GO:0009267 61 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
multi multicellular organism process GO:0044706 123 0.012
small molecule metabolic process GO:0044281 305 0.012
regulation of defense response GO:0031347 102 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
atp metabolic process GO:0046034 49 0.012
positive regulation of endopeptidase activity GO:0010950 26 0.012
protein catabolic process GO:0030163 101 0.012
cellular lipid metabolic process GO:0044255 83 0.012
response to lipopolysaccharide GO:0032496 4 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
response to endogenous stimulus GO:0009719 119 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
purine nucleoside metabolic process GO:0042278 127 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
metal ion transport GO:0030001 74 0.011
anatomical structure homeostasis GO:0060249 97 0.011
mrna processing GO:0006397 104 0.011
protein targeting GO:0006605 64 0.011
cellular macromolecule localization GO:0070727 220 0.011
cellular response to nutrient levels GO:0031669 62 0.011
proteolysis GO:0006508 192 0.011
response to bacterium GO:0009617 198 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
mitotic nuclear division GO:0007067 213 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
regulation of cell cycle process GO:0010564 181 0.011
negative regulation of cellular catabolic process GO:0031330 34 0.010
negative regulation of cell differentiation GO:0045596 143 0.010
cell aging GO:0007569 2 0.010
Yeast
protein import GO:0017038 55 0.010
eye morphogenesis GO:0048592 260 0.010

Jafrac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
disease of cellular proliferation DOID:14566 0 0.023
cancer DOID:162 0 0.023
organ system cancer DOID:0050686 0 0.018
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.015
neurodegenerative disease DOID:1289 0 0.013