Drosophila melanogaster

58 known processes

U2af38 (Dmel_CG3582)

U2 small nuclear riboprotein auxiliary factor 38

(Aliases: dU2AF[38],Dmel\CG3582,dU2AF38,l(2)06751,U2AF,CG3582,U2AF38,DU2AF38)

U2af38 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing GO:0008380 83 0.972
mrna metabolic process GO:0016071 124 0.950
mrna splicing via spliceosome GO:0000398 73 0.897
mrna processing GO:0006397 104 0.593
protein complex assembly GO:0006461 200 0.583
mitotic spindle organization GO:0007052 220 0.581
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.509
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.429
mitotic nuclear division GO:0007067 213 0.410
rna splicing via transesterification reactions GO:0000375 73 0.378
chromatin modification GO:0016568 147 0.344
chromatin organization GO:0006325 207 0.336
protein complex disassembly GO:0043241 36 0.314
regulation of protein metabolic process GO:0051246 256 0.307
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.300
cellular protein modification process GO:0006464 438 0.299
histone modification GO:0016570 106 0.280
negative regulation of rna metabolic process GO:0051253 251 0.276
dna conformation change GO:0071103 105 0.274
transcription from rna polymerase ii promoter GO:0006366 368 0.270
positive regulation of cellular biosynthetic process GO:0031328 316 0.235
regulation of organelle organization GO:0033043 196 0.225
positive regulation of biosynthetic process GO:0009891 316 0.222
protein modification process GO:0036211 438 0.222
regulation of cell cycle GO:0051726 291 0.207
regulation of cellular protein metabolic process GO:0032268 243 0.201
positive regulation of gene expression GO:0010628 290 0.200
chromosome organization GO:0051276 360 0.183
covalent chromatin modification GO:0016569 106 0.181
larval development GO:0002164 104 0.173
Worm
positive regulation of rna metabolic process GO:0051254 271 0.165
regulation of rna splicing GO:0043484 69 0.163
alternative mrna splicing via spliceosome GO:0000380 60 0.162
apoptotic process GO:0006915 159 0.156
negative regulation of signaling GO:0023057 219 0.154
rna processing GO:0006396 147 0.148
protein complex biogenesis GO:0070271 201 0.141
spindle organization GO:0007051 253 0.129
macromolecular complex assembly GO:0065003 256 0.127
regulation of mrna splicing via spliceosome GO:0048024 64 0.122
programmed cell death GO:0012501 257 0.108
embryo development ending in birth or egg hatching GO:0009792 152 0.107
Worm
establishment of localization in cell GO:0051649 402 0.103
vesicle mediated transport GO:0016192 381 0.101
nuclear division GO:0000280 332 0.100
cellular macromolecular complex assembly GO:0034622 153 0.100
positive regulation of nucleic acid templated transcription GO:1903508 266 0.097
peptidyl lysine modification GO:0018205 57 0.097
organelle fission GO:0048285 340 0.097
cellular component disassembly GO:0022411 46 0.095
regulation of cell division GO:0051302 72 0.095
negative regulation of cellular biosynthetic process GO:0031327 277 0.089
chromatin remodeling GO:0006338 72 0.089
regulation of mitotic cell cycle GO:0007346 190 0.081
positive regulation of transcription dna templated GO:0045893 266 0.078
negative regulation of gene expression GO:0010629 387 0.078
organelle assembly GO:0070925 198 0.077
regulation of apoptotic process GO:0042981 130 0.075
gene silencing GO:0016458 138 0.074
immune system process GO:0002376 347 0.074
positive regulation of molecular function GO:0044093 136 0.071
protein acetylation GO:0006473 39 0.066
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.066
regulation of cell cycle process GO:0010564 181 0.066
positive regulation of protein metabolic process GO:0051247 128 0.066
single organism intracellular transport GO:1902582 207 0.062
regulation of meiosis GO:0040020 3 0.061
protein acylation GO:0043543 42 0.061
death GO:0016265 284 0.058
negative regulation of rna biosynthetic process GO:1902679 240 0.058
response to other organism GO:0051707 293 0.055
negative regulation of cell communication GO:0010648 223 0.052
negative regulation of cellular metabolic process GO:0031324 382 0.050
cellular catabolic process GO:0044248 372 0.050
negative regulation of cellular protein metabolic process GO:0032269 85 0.049
endocytosis GO:0006897 310 0.049
histone acetylation GO:0016573 38 0.048
cell motility GO:0048870 251 0.047
regulation of response to stress GO:0080134 200 0.047
g2 dna damage checkpoint GO:0031572 69 0.046
regulation of chromatin silencing GO:0031935 36 0.045
catabolic process GO:0009056 409 0.044
cell cycle phase transition GO:0044770 140 0.043
regulation of mitotic cell cycle phase transition GO:1901990 130 0.043
regulation of programmed cell death GO:0043067 152 0.041
protein dna complex subunit organization GO:0071824 86 0.041
internal peptidyl lysine acetylation GO:0018393 38 0.040
regulation of molecular function GO:0065009 217 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
positive regulation of heterochromatin assembly GO:0031453 5 0.039
regulation of cell death GO:0010941 173 0.039
regulation of cellular component biogenesis GO:0044087 201 0.039
intracellular transport GO:0046907 228 0.038
regulation of multi organism process GO:0043900 131 0.038
cell migration GO:0016477 238 0.038
regulation of immune system process GO:0002682 176 0.037
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.037
development of primary sexual characteristics GO:0045137 50 0.036
Worm
peptidyl amino acid modification GO:0018193 105 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
sister chromatid segregation GO:0000819 92 0.035
organonitrogen compound metabolic process GO:1901564 318 0.035
methylation GO:0032259 47 0.035
regulation of response to external stimulus GO:0032101 115 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.034
regulation of mrna processing GO:0050684 71 0.034
cytoskeleton dependent cytokinesis GO:0061640 81 0.033
positive regulation of macromolecule metabolic process GO:0010604 405 0.033
regulation of heterochromatin assembly GO:0031445 8 0.033
meiotic cell cycle GO:0051321 171 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
immune response GO:0006955 246 0.032
regulation of gene silencing GO:0060968 63 0.032
regulation of protein modification process GO:0031399 112 0.032
negative regulation of mitotic cell cycle GO:0045930 109 0.032
chromatin silencing GO:0006342 76 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.031
cellular response to organic substance GO:0071310 132 0.031
negative regulation of apoptotic process GO:0043066 63 0.030
cellular macromolecule catabolic process GO:0044265 136 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.029
cellular protein complex assembly GO:0043623 71 0.029
negative regulation of cell cycle GO:0045786 116 0.029
positive regulation of cellular component organization GO:0051130 156 0.029
spindle assembly involved in mitosis GO:0090307 50 0.028
regulation of cellular amine metabolic process GO:0033238 3 0.028
protein maturation GO:0051604 71 0.028
cytokinesis GO:0000910 90 0.027
establishment of organelle localization GO:0051656 122 0.027
cell death GO:0008219 279 0.025
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
protein phosphorylation GO:0006468 169 0.024
body morphogenesis GO:0010171 2 0.024
intermediate filament based process GO:0045103 1 0.023
regionalization GO:0003002 416 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
dna templated transcription elongation GO:0006354 18 0.023
negative regulation of cellular component organization GO:0051129 108 0.022
centrosome organization GO:0051297 163 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
response to external biotic stimulus GO:0043207 293 0.021
organic substance catabolic process GO:1901575 308 0.021
aging GO:0007568 143 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.020
regulation of gene expression epigenetic GO:0040029 128 0.020
protein transport GO:0015031 155 0.020
regulation of mrna metabolic process GO:1903311 72 0.019
negative regulation of cell cycle process GO:0010948 109 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
molting cycle GO:0042303 56 0.018
Worm
intracellular protein transport GO:0006886 104 0.018
regulation of protein complex disassembly GO:0043244 29 0.018
macromolecule catabolic process GO:0009057 161 0.018
regulation of cell differentiation GO:0045595 302 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.017
regulation of proteolysis GO:0030162 87 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
proteolysis GO:0006508 192 0.017
negative regulation of cell proliferation GO:0008285 69 0.017
negative regulation of signal transduction GO:0009968 206 0.016
striated muscle myosin thick filament assembly GO:0071688 3 0.016
mrna cis splicing via spliceosome GO:0045292 1 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
male gamete generation GO:0048232 201 0.016
regulation of response to biotic stimulus GO:0002831 63 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
gonad development GO:0008406 50 0.016
Worm
reproductive system development GO:0061458 74 0.016
Worm
nitrogen compound transport GO:0071705 85 0.015
nucleosome organization GO:0034728 59 0.015
regulation of catalytic activity GO:0050790 185 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
chromosome segregation GO:0007059 157 0.014
phagocytosis GO:0006909 215 0.014
small molecule metabolic process GO:0044281 305 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
microtubule polymerization or depolymerization GO:0031109 39 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
nuclear migration GO:0007097 20 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of localization GO:0032879 275 0.014
regulation of growth GO:0040008 233 0.014
negative regulation of nucleoside metabolic process GO:0045978 1 0.013
developmental growth GO:0048589 280 0.013
peptidyl lysine acetylation GO:0018394 39 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
defense response GO:0006952 300 0.013
regulation of cell proliferation GO:0042127 163 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
homeostatic process GO:0042592 199 0.013
rna capping GO:0036260 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
camera type eye development GO:0043010 4 0.012
aromatic compound catabolic process GO:0019439 166 0.012
cytoplasmic transport GO:0016482 130 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
negative regulation of organelle organization GO:0010639 56 0.012
protein processing GO:0016485 68 0.012
interspecies interaction between organisms GO:0044419 16 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.011
intermediate filament cytoskeleton organization GO:0045104 1 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
mitotic cell cycle checkpoint GO:0007093 88 0.011
histone h2a acetylation GO:0043968 1 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
regulation of rac gtpase activity GO:0032314 1 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
regulation of nuclear division GO:0051783 58 0.011
amine metabolic process GO:0009308 12 0.011
multi organism behavior GO:0051705 175 0.011
intracellular signal transduction GO:0035556 300 0.010
protein localization GO:0008104 284 0.010
cellular amine metabolic process GO:0044106 12 0.010
positive regulation of catalytic activity GO:0043085 118 0.010

U2af38 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016