Drosophila melanogaster

29 known processes

LpR2 (Dmel_CG31092)

CG31092 gene product from transcript CG31092-RD

(Aliases: Dmel\CG31092,CG4823,CG4834,LDLR,Lpr2,CG31092)

LpR2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxygen containing compound GO:1901700 200 0.204
Rat
post embryonic appendage morphogenesis GO:0035120 385 0.145
appendage morphogenesis GO:0035107 397 0.122
metal ion homeostasis GO:0055065 44 0.120
cation homeostasis GO:0055080 51 0.118
cellular divalent inorganic cation homeostasis GO:0072503 23 0.103
chemical homeostasis GO:0048878 92 0.102
response to organic substance GO:0010033 284 0.099
Rat
imaginal disc derived appendage development GO:0048737 399 0.090
circadian rhythm GO:0007623 105 0.089
imaginal disc derived wing morphogenesis GO:0007476 337 0.085
ion homeostasis GO:0050801 55 0.085
appendage development GO:0048736 401 0.077
regulation of cell cycle GO:0051726 291 0.076
detection of stimulus GO:0051606 156 0.075
small molecule metabolic process GO:0044281 305 0.073
rhythmic behavior GO:0007622 76 0.072
response to extracellular stimulus GO:0009991 116 0.071
Rat
regulation of sequestering of triglyceride GO:0010889 3 0.071
regulation of synapse structure and activity GO:0050803 128 0.071
response to nutrient levels GO:0031667 114 0.067
Rat
catabolic process GO:0009056 409 0.064
lipid metabolic process GO:0006629 121 0.062
response to abiotic stimulus GO:0009628 341 0.060
Rat
cellular cation homeostasis GO:0030003 38 0.057
larval behavior GO:0030537 42 0.057
regulation of localization GO:0032879 275 0.053
developmental cell growth GO:0048588 52 0.053
neutral lipid metabolic process GO:0006638 12 0.052
cellular metal ion homeostasis GO:0006875 31 0.050
cellular lipid metabolic process GO:0044255 83 0.050
regulation of transport GO:0051049 181 0.050
regulation of cell proliferation GO:0042127 163 0.048
developmental growth involved in morphogenesis GO:0060560 65 0.046
developmental growth GO:0048589 280 0.045
response to radiation GO:0009314 155 0.045
purine containing compound metabolic process GO:0072521 155 0.044
cellular ion homeostasis GO:0006873 39 0.043
neurological system process GO:0050877 358 0.042
regulation of lipid metabolic process GO:0019216 15 0.040
regulation of lipid storage GO:0010883 22 0.040
adult behavior GO:0030534 137 0.040
glycerolipid metabolic process GO:0046486 34 0.039
homeostatic process GO:0042592 199 0.039
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
detection of visible light GO:0009584 38 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.038
organonitrogen compound biosynthetic process GO:1901566 117 0.037
single organism behavior GO:0044708 391 0.037
mating behavior GO:0007617 106 0.037
detection of light stimulus GO:0009583 58 0.036
mating GO:0007618 120 0.036
ion transport GO:0006811 145 0.036
taxis GO:0042330 304 0.036
triglyceride metabolic process GO:0006641 12 0.036
regulation of anatomical structure size GO:0090066 163 0.035
wing disc morphogenesis GO:0007472 344 0.035
axonogenesis GO:0007409 290 0.035
response to external biotic stimulus GO:0043207 293 0.035
Rat
organophosphate metabolic process GO:0019637 195 0.034
body morphogenesis GO:0010171 2 0.034
organophosphate biosynthetic process GO:0090407 46 0.034
neuron recognition GO:0008038 101 0.033
potassium ion transport GO:0006813 20 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.033
cell growth GO:0016049 108 0.033
ribose phosphate metabolic process GO:0019693 145 0.033
organic acid metabolic process GO:0006082 103 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
macromolecular complex assembly GO:0065003 256 0.032
organic substance transport GO:0071702 257 0.031
Human
axon development GO:0061564 297 0.031
circadian sleep wake cycle sleep GO:0050802 23 0.031
cell proliferation GO:0008283 299 0.029
calcium ion homeostasis GO:0055074 23 0.029
regulation of ion transport GO:0043269 39 0.029
single organism catabolic process GO:0044712 228 0.029
single organism biosynthetic process GO:0044711 206 0.029
endocytosis GO:0006897 310 0.029
Human Rat Fly
behavioral response to ethanol GO:0048149 49 0.029
circadian behavior GO:0048512 76 0.029
ras protein signal transduction GO:0007265 88 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.027
divalent inorganic cation homeostasis GO:0072507 29 0.027
establishment of localization in cell GO:0051649 402 0.027
chemosensory behavior GO:0007635 106 0.026
organic substance catabolic process GO:1901575 308 0.026
ethanolamine containing compound metabolic process GO:0042439 4 0.026
response to endogenous stimulus GO:0009719 119 0.025
Rat
regulation of cell cycle process GO:0010564 181 0.025
eye morphogenesis GO:0048592 260 0.025
cellular calcium ion homeostasis GO:0006874 21 0.025
cellular response to hormone stimulus GO:0032870 44 0.025
Rat
cellular response to oxygen containing compound GO:1901701 79 0.024
Rat
phagocytosis GO:0006909 215 0.024
cellular macromolecule localization GO:0070727 220 0.024
organic acid catabolic process GO:0016054 16 0.024
detection of chemical stimulus GO:0009593 93 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
intracellular signal transduction GO:0035556 300 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
cell cycle phase transition GO:0044770 140 0.023
oxoacid metabolic process GO:0043436 103 0.023
response to oxidative stress GO:0006979 86 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
anterior posterior axis specification embryo GO:0008595 103 0.022
positive regulation of catabolic process GO:0009896 105 0.022
sterol homeostasis GO:0055092 4 0.022
negative regulation of cell communication GO:0010648 223 0.022
leg disc morphogenesis GO:0007478 80 0.021
regulation of catabolic process GO:0009894 170 0.021
response to reactive oxygen species GO:0000302 24 0.020
defense response to bacterium GO:0042742 178 0.020
g protein coupled receptor signaling pathway GO:0007186 136 0.020
response to nitrogen compound GO:1901698 90 0.020
Rat
multi organism reproductive behavior GO:0044705 121 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
cellular homeostasis GO:0019725 80 0.020
regulation of catalytic activity GO:0050790 185 0.020
oocyte development GO:0048599 124 0.020
flight behavior GO:0007629 26 0.020
eye development GO:0001654 323 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
extrinsic apoptotic signaling pathway GO:0097191 1 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
Rat
intracellular transport GO:0046907 228 0.019
regulation of cellular localization GO:0060341 136 0.019
response to bacterium GO:0009617 198 0.019
Rat
regulation of cellular amine metabolic process GO:0033238 3 0.019
tripartite regional subdivision GO:0007351 103 0.018
regulation of neuron differentiation GO:0045664 103 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
axon extension GO:0048675 32 0.018
regionalization GO:0003002 416 0.018
lipid homeostasis GO:0055088 33 0.018
nucleotide metabolic process GO:0009117 161 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.018
defense response GO:0006952 300 0.018
response to other organism GO:0051707 293 0.018
Rat
response to decreased oxygen levels GO:0036293 58 0.018
Rat
purine nucleoside metabolic process GO:0042278 127 0.018
protein catabolic process GO:0030163 101 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.018
programmed cell death GO:0012501 257 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of nervous system development GO:0051960 248 0.017
cellular response to organic substance GO:0071310 132 0.017
Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
positive regulation of cell communication GO:0010647 250 0.017
maintenance of location GO:0051235 73 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
cation transport GO:0006812 110 0.016
positive regulation of lipid storage GO:0010884 4 0.016
macromolecule catabolic process GO:0009057 161 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
lipid modification GO:0030258 24 0.016
regulation of cell differentiation GO:0045595 302 0.016
heterocycle catabolic process GO:0046700 166 0.016
apoptotic process GO:0006915 159 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.016
neuron projection extension GO:1990138 32 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
triglyceride biosynthetic process GO:0019432 2 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
extracellular structure organization GO:0043062 46 0.016
rhythmic process GO:0048511 106 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
amine metabolic process GO:0009308 12 0.016
regulation of actin filament based process GO:0032970 42 0.015
regulation of cell development GO:0060284 215 0.015
response to organonitrogen compound GO:0010243 75 0.015
Rat
larval locomotory behavior GO:0008345 27 0.015
response to inorganic substance GO:0010035 44 0.015
protein localization GO:0008104 284 0.015
Human
anterior posterior axis specification GO:0009948 109 0.015
detection of stimulus involved in sensory perception GO:0050906 92 0.015
locomotor rhythm GO:0045475 56 0.015
response to biotic stimulus GO:0009607 294 0.015
Rat
multi organism behavior GO:0051705 175 0.015
lipid biosynthetic process GO:0008610 46 0.015
cell death GO:0008219 279 0.015
protein complex biogenesis GO:0070271 201 0.015
locomotory behavior GO:0007626 176 0.015
ion transmembrane transport GO:0034220 122 0.015
embryonic pattern specification GO:0009880 174 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
acylglycerol biosynthetic process GO:0046463 2 0.015
fatty acid beta oxidation GO:0006635 6 0.015
metal ion transport GO:0030001 74 0.015
regulation of hydrolase activity GO:0051336 97 0.014
aromatic compound catabolic process GO:0019439 166 0.014
cellular catabolic process GO:0044248 372 0.014
response to lipopolysaccharide GO:0032496 4 0.014
Rat
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
regulation of organelle organization GO:0033043 196 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
cellular response to ethanol GO:0071361 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
xenobiotic transport GO:0042908 1 0.014
cation transmembrane transport GO:0098655 88 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
compound eye development GO:0048749 307 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
heart contraction GO:0060047 26 0.014
glycerophospholipid metabolic process GO:0006650 23 0.014
transmembrane transport GO:0055085 139 0.014
regulation of synaptic transmission GO:0050804 69 0.014
cellular protein modification process GO:0006464 438 0.014
cranial nerve development GO:0021545 1 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
response to wounding GO:0009611 94 0.013
positive regulation of cell cycle GO:0045787 43 0.013
leg disc development GO:0035218 92 0.013
circulatory system process GO:0003013 37 0.013
nucleoside catabolic process GO:0009164 112 0.013
single organism membrane organization GO:0044802 93 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
organelle localization GO:0051640 148 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.013
cell cycle g1 s phase transition GO:0044843 31 0.013
regulation of steroid metabolic process GO:0019218 2 0.013
membrane organization GO:0061024 112 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
spindle organization GO:0007051 253 0.013
chemotaxis GO:0006935 249 0.013
cellular chemical homeostasis GO:0055082 40 0.013
positive regulation of signal transduction GO:0009967 223 0.013
actin mediated cell contraction GO:0070252 21 0.013
neuromuscular junction development GO:0007528 149 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
regulation of developmental growth GO:0048638 174 0.013
cholesterol homeostasis GO:0042632 3 0.013
muscle system process GO:0003012 21 0.012
protein complex assembly GO:0006461 200 0.012
xenobiotic catabolic process GO:0042178 1 0.012
single organism intracellular transport GO:1902582 207 0.012
death GO:0016265 284 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
heart process GO:0003015 37 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
growth GO:0040007 359 0.012
anion homeostasis GO:0055081 3 0.012
segmentation GO:0035282 207 0.012
defense response to other organism GO:0098542 225 0.012
synaptic transmission GO:0007268 288 0.012
single organism cellular localization GO:1902580 180 0.012
embryonic axis specification GO:0000578 107 0.012
compound eye morphogenesis GO:0001745 249 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
neutral lipid biosynthetic process GO:0046460 2 0.012
establishment of protein localization GO:0045184 163 0.011
Human
carbohydrate derivative catabolic process GO:1901136 118 0.011
anterior posterior pattern specification GO:0009952 136 0.011
regulation of cell division GO:0051302 72 0.011
cellular ketone metabolic process GO:0042180 24 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
immune system process GO:0002376 347 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
protein modification process GO:0036211 438 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
forebrain development GO:0030900 2 0.011
Rat
morphogenesis of an epithelium GO:0002009 276 0.011
regulation of apoptotic process GO:0042981 130 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
positive regulation of molecular function GO:0044093 136 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
smoothened signaling pathway GO:0007224 49 0.010
meiotic cell cycle GO:0051321 171 0.010
negative regulation of signal transduction GO:0009968 206 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
response to heat GO:0009408 63 0.010
gland development GO:0048732 191 0.010
response to light stimulus GO:0009416 124 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
response to oxygen levels GO:0070482 59 0.010
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.010
mitotic spindle organization GO:0007052 220 0.010
monocarboxylic acid transport GO:0015718 3 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
long chain fatty acid metabolic process GO:0001676 3 0.010
acylglycerol catabolic process GO:0046464 3 0.010
adult locomotory behavior GO:0008344 76 0.010
energy derivation by oxidation of organic compounds GO:0015980 32 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
immune response activating signal transduction GO:0002757 2 0.010
regulation of immune system process GO:0002682 176 0.010
cellular response to light stimulus GO:0071482 37 0.010
monovalent inorganic cation transport GO:0015672 40 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
inorganic cation transmembrane transport GO:0098662 61 0.010

LpR2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.144
nervous system disease DOID:863 0 0.054
cardiovascular system disease DOID:1287 0 0.031
musculoskeletal system disease DOID:17 0 0.015
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
disease of metabolism DOID:0014667 0 0.010