Drosophila melanogaster

2 known processes

Est-P (Dmel_CG17148)

Esterase P

(Aliases: yEst-6,CG17148,PsiEst-6,EST-5,psiEst-6,yEst6,Dmel\CG17148,est-P,Est7,ESTP,Est-7,Est-5,EstP)

Est-P biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hormone catabolic process GO:0042447 3 0.080
Fly
single organism behavior GO:0044708 391 0.069
Fly
humoral immune response GO:0006959 117 0.055
vesicle mediated transport GO:0016192 381 0.045
establishment of localization in cell GO:0051649 402 0.045
courtship behavior GO:0007619 68 0.044
Fly
response to organic substance GO:0010033 284 0.044
Fly
regulation of cell cycle GO:0051726 291 0.043
response to biotic stimulus GO:0009607 294 0.042
endocytosis GO:0006897 310 0.042
phagocytosis GO:0006909 215 0.042
multi organism behavior GO:0051705 175 0.041
Fly
adult behavior GO:0030534 137 0.040
Fly
response to other organism GO:0051707 293 0.039
defense response GO:0006952 300 0.038
actin filament based process GO:0030029 220 0.036
response to external biotic stimulus GO:0043207 293 0.035
organonitrogen compound metabolic process GO:1901564 318 0.035
cellular catabolic process GO:0044248 372 0.034
Fly
response to bacterium GO:0009617 198 0.033
immune system process GO:0002376 347 0.033
sensory perception of salty taste GO:0050914 3 0.033
cellular response to chemical stimulus GO:0070887 199 0.032
salt aversion GO:0035199 3 0.031
catabolic process GO:0009056 409 0.031
Fly
secondary metabolic process GO:0019748 75 0.031
Fly
mitotic dna integrity checkpoint GO:0044774 75 0.031
body morphogenesis GO:0010171 2 0.030
pheromone biosynthetic process GO:0042811 3 0.029
Fly
camera type eye development GO:0043010 4 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
small molecule metabolic process GO:0044281 305 0.028
tissue morphogenesis GO:0048729 297 0.028
neurological system process GO:0050877 358 0.028
immune response GO:0006955 246 0.028
response to lipopolysaccharide GO:0032496 4 0.027
wound healing GO:0042060 75 0.027
oxoacid metabolic process GO:0043436 103 0.027
behavioral response to ethanol GO:0048149 49 0.027
Fly
appendage development GO:0048736 401 0.027
regulation of cell shape GO:0008360 113 0.026
actin cytoskeleton organization GO:0030036 206 0.025
sensory perception GO:0007600 196 0.025
sensory perception of chemical stimulus GO:0007606 116 0.025
response to wounding GO:0009611 94 0.025
response to oxygen containing compound GO:1901700 200 0.024
Fly
protein modification process GO:0036211 438 0.024
organic acid metabolic process GO:0006082 103 0.024
negative regulation of cell cycle GO:0045786 116 0.024
regulation of cell cycle process GO:0010564 181 0.023
chromatin organization GO:0006325 207 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
gland development GO:0048732 191 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
salivary gland development GO:0007431 162 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
transcription from rna polymerase ii promoter GO:0006366 368 0.022
protein localization GO:0008104 284 0.022
developmental programmed cell death GO:0010623 138 0.022
cellular protein modification process GO:0006464 438 0.022
regionalization GO:0003002 416 0.022
organic substance catabolic process GO:1901575 308 0.021
Fly
defense response to other organism GO:0098542 225 0.021
death GO:0016265 284 0.021
pigment metabolic process GO:0042440 84 0.021
response to abiotic stimulus GO:0009628 341 0.021
gland morphogenesis GO:0022612 145 0.021
organelle assembly GO:0070925 198 0.020
response to alcohol GO:0097305 95 0.020
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
organelle fission GO:0048285 340 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
intracellular transport GO:0046907 228 0.020
nuclear division GO:0000280 332 0.020
actin filament organization GO:0007015 126 0.020
cell division GO:0051301 248 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
cellular homeostasis GO:0019725 80 0.020
exocrine system development GO:0035272 162 0.020
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.019
detection of stimulus involved in sensory perception GO:0050906 92 0.019
establishment of protein localization GO:0045184 163 0.019
anatomical structure homeostasis GO:0060249 97 0.019
chromosome organization GO:0051276 360 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
response to glucose GO:0009749 2 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
forebrain development GO:0030900 2 0.018
cellular response to organic substance GO:0071310 132 0.018
positive regulation of cell communication GO:0010647 250 0.018
immune effector process GO:0002252 98 0.018
sensory organ morphogenesis GO:0090596 260 0.018
dendrite morphogenesis GO:0048813 199 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
defense response to bacterium GO:0042742 178 0.018
reproductive behavior GO:0019098 122 0.018
Fly
detection of stimulus GO:0051606 156 0.018
benzene containing compound metabolic process GO:0042537 3 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of transport GO:0051049 181 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
multi multicellular organism process GO:0044706 123 0.017
Fly
response to hexose GO:0009746 3 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
response to nitrogen compound GO:1901698 90 0.017
innate immune response GO:0045087 144 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
spindle organization GO:0007051 253 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
response to monosaccharide GO:0034284 4 0.017
wing disc morphogenesis GO:0007472 344 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
positive regulation of signal transduction GO:0009967 223 0.017
kidney development GO:0001822 3 0.017
estrogen metabolic process GO:0008210 1 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
positive regulation of cell migration GO:0030335 2 0.017
mating GO:0007618 120 0.016
Fly
chemotaxis GO:0006935 249 0.016
sensory perception of smell GO:0007608 80 0.016
regulation of localization GO:0032879 275 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
dna metabolic process GO:0006259 227 0.016
salivary gland morphogenesis GO:0007435 145 0.016
macromolecule catabolic process GO:0009057 161 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
lateral inhibition GO:0046331 206 0.016
homeostatic process GO:0042592 199 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
hindbrain development GO:0030902 2 0.016
mitotic g2 dna damage checkpoint GO:0007095 69 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
regulation of protein metabolic process GO:0051246 256 0.016
retina development in camera type eye GO:0060041 4 0.016
cellular macromolecule catabolic process GO:0044265 136 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
positive regulation of signaling GO:0023056 243 0.015
pigment biosynthetic process GO:0046148 36 0.015
respiratory system development GO:0060541 213 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
negative regulation of gene expression GO:0010629 387 0.015
store operated calcium entry GO:0002115 3 0.015
macromolecular complex assembly GO:0065003 256 0.015
response to endogenous stimulus GO:0009719 119 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
localization of cell GO:0051674 257 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
ion transport GO:0006811 145 0.015
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.015
purine containing compound metabolic process GO:0072521 155 0.015
inter male aggressive behavior GO:0002121 60 0.015
regulation of molecular function GO:0065009 217 0.015
cell proliferation GO:0008283 299 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
protein heterooligomerization GO:0051291 4 0.015
salivary gland histolysis GO:0035070 88 0.014
response to extracellular stimulus GO:0009991 116 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
regulation of response to stress GO:0080134 200 0.014
tissue death GO:0016271 102 0.014
heterocycle catabolic process GO:0046700 166 0.014
intracellular signal transduction GO:0035556 300 0.014
cellular macromolecule localization GO:0070727 220 0.014
cellular response to peptide hormone stimulus GO:0071375 28 0.014
dna integrity checkpoint GO:0031570 81 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
g2 dna damage checkpoint GO:0031572 69 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
positive regulation of lipid storage GO:0010884 4 0.014
positive regulation of catabolic process GO:0009896 105 0.014
histolysis GO:0007559 102 0.014
carbohydrate derivative biosynthetic process GO:1901137 85 0.014
cellular ketone metabolic process GO:0042180 24 0.014
aromatic compound catabolic process GO:0019439 166 0.014
cellular response to ethanol GO:0071361 4 0.014
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
cellular hormone metabolic process GO:0034754 23 0.014
Fly
axis specification GO:0009798 167 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
cellular amine metabolic process GO:0044106 12 0.014
cellular protein localization GO:0034613 160 0.014
proteolysis GO:0006508 192 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of gene expression GO:0010628 290 0.013
response to organophosphorus GO:0046683 2 0.013
androgen metabolic process GO:0008209 1 0.013
epithelial cell differentiation GO:0030855 322 0.013
regulation of catabolic process GO:0009894 170 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
xenobiotic catabolic process GO:0042178 1 0.013
eye development GO:0001654 323 0.013
nephron tubule development GO:0072080 3 0.013
organophosphate metabolic process GO:0019637 195 0.013
tube development GO:0035295 244 0.013
negative regulation of developmental process GO:0051093 201 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
endomembrane system organization GO:0010256 119 0.013
gene silencing GO:0016458 138 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
drinking behavior GO:0042756 2 0.013
regulation of organelle organization GO:0033043 196 0.013
dna damage checkpoint GO:0000077 78 0.013
positive regulation of cell motility GO:2000147 3 0.013
pigmentation GO:0043473 75 0.013
appendage morphogenesis GO:0035107 397 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
nad metabolic process GO:0019674 1 0.013
protein complex assembly GO:0006461 200 0.013
cell cycle checkpoint GO:0000075 95 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
negative regulation of signal transduction GO:0009968 206 0.013
hormone metabolic process GO:0042445 33 0.013
Fly
segmentation GO:0035282 207 0.013
antimicrobial humoral response GO:0019730 99 0.013
cell cycle phase transition GO:0044770 140 0.013
nucleoside metabolic process GO:0009116 127 0.013
limb development GO:0060173 1 0.013
kidney epithelium development GO:0072073 3 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
mitotic spindle organization GO:0007052 220 0.013
response to organonitrogen compound GO:0010243 75 0.013
central nervous system development GO:0007417 201 0.012
response to ethanol GO:0045471 59 0.012
Fly
camera type eye morphogenesis GO:0048593 2 0.012
secretion GO:0046903 109 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
developmental maturation GO:0021700 172 0.012
mesoderm development GO:0007498 78 0.012
embryonic pattern specification GO:0009880 174 0.012
chemosensory behavior GO:0007635 106 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
nephron development GO:0072006 3 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
mesenchymal cell development GO:0014031 1 0.012
compound eye morphogenesis GO:0001745 249 0.012
telencephalon development GO:0021537 2 0.012
melanin metabolic process GO:0006582 47 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
connective tissue development GO:0061448 3 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
alditol phosphate metabolic process GO:0052646 2 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
metal ion transport GO:0030001 74 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
negative regulation of cell communication GO:0010648 223 0.012
eye morphogenesis GO:0048592 260 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
single organism biosynthetic process GO:0044711 206 0.012
Fly
mitotic nuclear division GO:0007067 213 0.012
aggressive behavior GO:0002118 63 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
amine metabolic process GO:0009308 12 0.012
steroid catabolic process GO:0006706 1 0.012
response to starvation GO:0042594 97 0.012
cell migration GO:0016477 238 0.012
compound eye development GO:0048749 307 0.012
multi organism reproductive behavior GO:0044705 121 0.012
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.012
autophagy GO:0006914 108 0.012
regulation of multi organism process GO:0043900 131 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
meiotic cell cycle process GO:1903046 132 0.012
positive regulation of molecular function GO:0044093 136 0.012
immune response activating signal transduction GO:0002757 2 0.012
cellular response to insulin stimulus GO:0032869 28 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.011
protein transport GO:0015031 155 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
cell death GO:0008219 279 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
male mating behavior GO:0060179 70 0.011
Fly
chromosome separation GO:0051304 42 0.011
lipid metabolic process GO:0006629 121 0.011
Fly
epithelial cell development GO:0002064 274 0.011
nephron epithelium development GO:0072009 3 0.011
autophagic cell death GO:0048102 83 0.011
regulation of cell differentiation GO:0045595 302 0.011
cholesterol homeostasis GO:0042632 3 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
locomotory behavior GO:0007626 176 0.011
ras protein signal transduction GO:0007265 88 0.011
response to radiation GO:0009314 155 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
triglyceride biosynthetic process GO:0019432 2 0.011
anion homeostasis GO:0055081 3 0.011
kidney morphogenesis GO:0060993 3 0.011
blastoderm segmentation GO:0007350 159 0.011
detection of chemical stimulus GO:0009593 93 0.011
purine nucleoside biosynthetic process GO:0042451 3 0.011
cell maturation GO:0048469 144 0.011
muscle structure development GO:0061061 224 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
regulation of hydrolase activity GO:0051336 97 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
organic substance transport GO:0071702 257 0.011
programmed cell death GO:0012501 257 0.011
limb morphogenesis GO:0035108 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
nucleoside catabolic process GO:0009164 112 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of mapk cascade GO:0043408 92 0.011
embryonic morphogenesis GO:0048598 206 0.011
ribonucleoside biosynthetic process GO:0042455 3 0.011
neuromuscular junction development GO:0007528 149 0.011
negative regulation of developmental growth GO:0048640 64 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
reciprocal dna recombination GO:0035825 19 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
developmental pigmentation GO:0048066 68 0.011
response to sterol GO:0036314 34 0.011
cell projection assembly GO:0030031 94 0.010
mrna metabolic process GO:0016071 124 0.010
mating behavior GO:0007617 106 0.010
Fly
g protein coupled receptor signaling pathway GO:0007186 136 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
response to pain GO:0048265 3 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
negative regulation of cellular metabolic process GO:0031324 382 0.010
sensory perception of pain GO:0019233 4 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
nitrogen compound transport GO:0071705 85 0.010
notch signaling pathway GO:0007219 120 0.010
glycerolipid catabolic process GO:0046503 3 0.010
response to temperature stimulus GO:0009266 106 0.010
cellular response to peptide GO:1901653 28 0.010
positive regulation of response to external stimulus GO:0032103 44 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
protein phosphorylation GO:0006468 169 0.010
apoptotic process GO:0006915 159 0.010
single organism cellular localization GO:1902580 180 0.010
purine containing compound biosynthetic process GO:0072522 30 0.010
digestive tract morphogenesis GO:0048546 127 0.010

Est-P disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
cardiovascular system disease DOID:1287 0 0.015
nervous system disease DOID:863 0 0.015
urinary system disease DOID:18 0 0.012
kidney disease DOID:557 0 0.011
musculoskeletal system disease DOID:17 0 0.010