Drosophila melanogaster

249 known processes

kay (Dmel_CG33956)

kayak

(Aliases: dFRA,Fra,Dfos,c-fos,Fos,AP-1,AP1,dAP-1,dFra,D-fos,DFra,CG33956,dfos,fos,Dmel\CG33956,D-Fos,fbz,dlhD,Kay,D-fos/kay,CG15507,dFos,d-fos,CG15509,DFos,DFOS,c-Fos)

kay biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular biosynthetic process GO:0031327 277 1.000
Mouse Rat
negative regulation of transcription dna templated GO:0045892 237 0.998
Mouse Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.998
Mouse Rat
epithelial cell migration GO:0010631 148 0.998
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.997
Human
negative regulation of rna metabolic process GO:0051253 251 0.987
Mouse Rat
dendrite development GO:0016358 204 0.986
negative regulation of rna biosynthetic process GO:1902679 240 0.986
Mouse Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.985
Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.982
Human
morphogenesis of an epithelium GO:0002009 276 0.980
central nervous system development GO:0007417 201 0.980
dendrite morphogenesis GO:0048813 199 0.980
regulation of programmed cell death GO:0043067 152 0.976
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.973
transcription from rna polymerase ii promoter GO:0006366 368 0.972
tissue morphogenesis GO:0048729 297 0.969
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.969
positive regulation of rna metabolic process GO:0051254 271 0.963
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.957
Human
regulation of phosphate metabolic process GO:0019220 210 0.956
regulation of intracellular signal transduction GO:1902531 236 0.951
positive regulation of biosynthetic process GO:0009891 316 0.942
negative regulation of signal transduction GO:0009968 206 0.939
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.938
Mouse Rat
regulation of cell death GO:0010941 173 0.935
Rat
regulation of protein metabolic process GO:0051246 256 0.927
death GO:0016265 284 0.926
Rat
negative regulation of cellular metabolic process GO:0031324 382 0.919
Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 240 0.918
Mouse Rat
positive regulation of signaling GO:0023056 243 0.912
regulation of apoptotic process GO:0042981 130 0.896
Rat
synapse organization GO:0050808 196 0.883
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.878
Mouse Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.870
rhythmic process GO:0048511 106 0.866
regulation of immune system process GO:0002682 176 0.846
Mouse
apoptotic process GO:0006915 159 0.843
Rat
negative regulation of cell communication GO:0010648 223 0.841
regulation of cell differentiation GO:0045595 302 0.838
Mouse
phosphorylation GO:0016310 294 0.835
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.831
positive regulation of gene expression GO:0010628 290 0.824
stem cell differentiation GO:0048863 117 0.818
regulation of neuromuscular synaptic transmission GO:1900073 15 0.804
positive regulation of molecular function GO:0044093 136 0.802
Rat
photoreceptor cell differentiation GO:0046530 170 0.798
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.794
Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.786
regulation of protein modification process GO:0031399 112 0.773
regulation of cell proliferation GO:0042127 163 0.771
Mouse Rat
micropyle formation GO:0046844 4 0.771
regulation of protein phosphorylation GO:0001932 64 0.769
muscle structure development GO:0061061 224 0.769
Mouse
anterior midgut ectodermal morphogenesis GO:0007441 4 0.763
embryonic morphogenesis GO:0048598 206 0.760
negative regulation of intracellular signal transduction GO:1902532 57 0.760
appendage morphogenesis GO:0035107 397 0.757
establishment of ommatidial planar polarity GO:0042067 49 0.757
positive regulation of nucleic acid templated transcription GO:1903508 266 0.755
circadian rhythm GO:0007623 105 0.748
regulation of phosphorylation GO:0042325 147 0.744
activation of protein kinase activity GO:0032147 12 0.739
regulation of protein kinase activity GO:0045859 51 0.738
intracellular signal transduction GO:0035556 300 0.726
cell death GO:0008219 279 0.720
Rat
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.714
actin filament based process GO:0030029 220 0.705
positive regulation of cellular biosynthetic process GO:0031328 316 0.702
regulation of kinase activity GO:0043549 53 0.696
positive regulation of cellular component organization GO:0051130 156 0.696
Mouse
mapk cascade GO:0000165 107 0.687
negative regulation of biosynthetic process GO:0009890 277 0.686
Mouse Rat
regulation of transferase activity GO:0051338 58 0.647
response to hydrogen peroxide GO:0042542 11 0.634
Rat
morphogenesis of embryonic epithelium GO:0016331 94 0.607
chromatin organization GO:0006325 207 0.602
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.602
programmed cell death GO:0012501 257 0.595
Rat
eye morphogenesis GO:0048592 260 0.593
positive regulation of cell communication GO:0010647 250 0.566
regulation of dendrite morphogenesis GO:0048814 28 0.564
sensory organ morphogenesis GO:0090596 260 0.562
compound eye photoreceptor fate commitment GO:0001752 36 0.561
photoreceptor cell fate commitment GO:0046552 41 0.556
bmp signaling pathway GO:0030509 27 0.556
positive regulation of response to stimulus GO:0048584 323 0.552
gliogenesis GO:0042063 80 0.550
embryonic ectodermal digestive tract development GO:0048611 4 0.544
embryonic development via the syncytial blastoderm GO:0001700 148 0.544
germ band shortening GO:0007390 19 0.541
positive regulation of phosphorus metabolic process GO:0010562 139 0.538
hindgut morphogenesis GO:0007442 58 0.523
digestive tract morphogenesis GO:0048546 127 0.517
regulation of localization GO:0032879 275 0.516
negative regulation of signaling GO:0023057 219 0.515
growth GO:0040007 359 0.506
neuron fate commitment GO:0048663 50 0.499
regulation of transport GO:0051049 181 0.489
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.485
imaginal disc derived appendage morphogenesis GO:0035114 395 0.484
negative regulation of cell death GO:0060548 81 0.478
digestive tract development GO:0048565 149 0.475
positive regulation of jun kinase activity GO:0043507 4 0.472
regulation of protein serine threonine kinase activity GO:0071900 25 0.467
wing disc morphogenesis GO:0007472 344 0.466
defense response to other organism GO:0098542 225 0.459
digestive system development GO:0055123 149 0.457
regulation of molecular function GO:0065009 217 0.457
brain development GO:0007420 120 0.454
positive regulation of signal transduction GO:0009967 223 0.451
genital disc development GO:0035215 44 0.442
axon development GO:0061564 297 0.437
macromolecular complex assembly GO:0065003 256 0.433
regulation of terminal button organization GO:2000331 11 0.432
regulation of anatomical structure morphogenesis GO:0022603 242 0.421
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.420
tube development GO:0035295 244 0.417
regulation of nervous system development GO:0051960 248 0.415
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.403
positive regulation of protein kinase activity GO:0045860 25 0.396
larval development GO:0002164 104 0.396
appendage development GO:0048736 401 0.395
positive regulation of cellular protein metabolic process GO:0032270 118 0.394
Mouse
imaginal disc derived appendage development GO:0048737 399 0.391
negative regulation of response to stimulus GO:0048585 258 0.388
autophagy GO:0006914 108 0.380
ectodermal digestive tract morphogenesis GO:0048567 7 0.378
regulation of cell development GO:0060284 215 0.376
regulation of phosphorus metabolic process GO:0051174 210 0.375
negative regulation of gene expression GO:0010629 387 0.372
Mouse Rat
chemical homeostasis GO:0048878 92 0.372
negative regulation of cell differentiation GO:0045596 143 0.366
Mouse
regulation of synapse structure and activity GO:0050803 128 0.347
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.346
response to axon injury GO:0048678 12 0.345
axon regeneration GO:0031103 8 0.344
muscle tissue development GO:0060537 30 0.341
Mouse
protein localization GO:0008104 284 0.340
regulation of multicellular organismal development GO:2000026 414 0.337
Mouse
regulation of mapk cascade GO:0043408 92 0.334
border follicle cell migration GO:0007298 113 0.332
ovarian follicle cell development GO:0030707 248 0.327
positive regulation of phosphate metabolic process GO:0045937 139 0.325
eye development GO:0001654 323 0.324
synapse assembly GO:0007416 143 0.321
cell growth GO:0016049 108 0.319
muscle system process GO:0003012 21 0.317
cellular response to oxygen containing compound GO:1901701 79 0.314
Human
synaptic transmission GO:0007268 288 0.311
regulation of organelle organization GO:0033043 196 0.309
Mouse
positive regulation of catalytic activity GO:0043085 118 0.308
locomotory behavior GO:0007626 176 0.308
paracrine signaling GO:0038001 7 0.307
compound eye morphogenesis GO:0001745 249 0.304
actin cytoskeleton organization GO:0030036 206 0.303
morphogenesis of a polarized epithelium GO:0001738 93 0.300
developmental maturation GO:0021700 172 0.298
response to growth factor GO:0070848 31 0.296
Human
eye photoreceptor cell fate commitment GO:0042706 37 0.296
regulation of neurogenesis GO:0050767 158 0.283
regulation of neuron projection development GO:0010975 69 0.275
regulation of neurotransmitter levels GO:0001505 38 0.268
compound eye photoreceptor cell differentiation GO:0001751 140 0.261
head development GO:0060322 135 0.256
regulation of neuroblast proliferation GO:1902692 34 0.255
establishment or maintenance of cell polarity GO:0007163 167 0.254
immune response GO:0006955 246 0.254
response to abiotic stimulus GO:0009628 341 0.251
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.249
protein complex assembly GO:0006461 200 0.245
actin filament organization GO:0007015 126 0.241
positive regulation of phosphorylation GO:0042327 87 0.240
jak stat cascade GO:0007259 49 0.235
imaginal disc eversion GO:0007561 4 0.234
defense response to bacterium GO:0042742 178 0.233
negative regulation of multicellular organismal process GO:0051241 142 0.232
positive regulation of programmed cell death GO:0043068 62 0.229
Rat
hindgut development GO:0061525 58 0.228
eye photoreceptor cell differentiation GO:0001754 145 0.212
stress activated mapk cascade GO:0051403 52 0.212
positive regulation of protein metabolic process GO:0051247 128 0.210
Mouse
cellular response to abiotic stimulus GO:0071214 58 0.210
protein phosphorylation GO:0006468 169 0.210
carbohydrate homeostasis GO:0033500 12 0.208
signal transduction by phosphorylation GO:0023014 107 0.207
imaginal disc derived wing morphogenesis GO:0007476 337 0.204
regulation of cell morphogenesis GO:0022604 163 0.204
regulation of humoral immune response GO:0002920 51 0.198
learning or memory GO:0007611 141 0.198
Rat
negative regulation of apoptotic process GO:0043066 63 0.197
positive regulation of protein phosphorylation GO:0001934 34 0.193
glial cell differentiation GO:0010001 35 0.193
tissue migration GO:0090130 155 0.191
neuromuscular synaptic transmission GO:0007274 67 0.189
cellular protein modification process GO:0006464 438 0.189
heart process GO:0003015 37 0.189
positive regulation of transferase activity GO:0051347 26 0.188
multicellular organismal aging GO:0010259 140 0.186
positive regulation of neurogenesis GO:0050769 41 0.186
cell cycle g1 s phase transition GO:0044843 31 0.185
determination of adult lifespan GO:0008340 137 0.183
negative regulation of cell proliferation GO:0008285 69 0.181
Rat
regulation of cell shape GO:0008360 113 0.181
response to oxidative stress GO:0006979 86 0.178
Human Rat
small gtpase mediated signal transduction GO:0007264 88 0.173
negative regulation of neuron death GO:1901215 18 0.170
synaptic growth at neuromuscular junction GO:0051124 119 0.170
gonad development GO:0008406 50 0.164
small molecule metabolic process GO:0044281 305 0.164
taxis GO:0042330 304 0.163
forebrain development GO:0030900 2 0.160
chemosensory behavior GO:0007635 106 0.160
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.160
male gamete generation GO:0048232 201 0.158
cellular response to endogenous stimulus GO:0071495 80 0.158
Human Rat
sex differentiation GO:0007548 81 0.157
tube morphogenesis GO:0035239 191 0.155
positive regulation of cell differentiation GO:0045597 64 0.155
Mouse
establishment of localization in cell GO:0051649 402 0.155
response to oxygen containing compound GO:1901700 200 0.155
Human Rat
chromosome organization GO:0051276 360 0.154
Mouse
regulation of cell cycle GO:0051726 291 0.151
endocytosis GO:0006897 310 0.150
response to hormone GO:0009725 45 0.149
Rat
regulation of heart contraction GO:0008016 21 0.148
immune effector process GO:0002252 98 0.147
positive regulation of transcription dna templated GO:0045893 266 0.145
positive regulation of transport GO:0051050 92 0.145
regionalization GO:0003002 416 0.144
organophosphate metabolic process GO:0019637 195 0.143
neuron neuron synaptic transmission GO:0007270 14 0.143
muscle organ development GO:0007517 127 0.143
Mouse
negative regulation of immune system process GO:0002683 50 0.142
compound eye development GO:0048749 307 0.141
epithelium migration GO:0090132 148 0.139
regulation of small gtpase mediated signal transduction GO:0051056 93 0.139
positive regulation of nervous system development GO:0051962 69 0.138
learning GO:0007612 75 0.138
Rat
chromatin modification GO:0016568 147 0.136
Mouse
response to lipopolysaccharide GO:0032496 4 0.136
Rat
ameboidal type cell migration GO:0001667 151 0.135
spinal cord development GO:0021510 1 0.132
oocyte development GO:0048599 124 0.131
positive regulation of kinase activity GO:0033674 25 0.129
cellular response to cadmium ion GO:0071276 6 0.128
columnar cuboidal epithelial cell development GO:0002066 249 0.127
establishment of planar polarity GO:0001736 87 0.125
positive regulation of intracellular signal transduction GO:1902533 116 0.125
negative regulation of developmental process GO:0051093 201 0.124
Mouse
regulation of catalytic activity GO:0050790 185 0.124
response to organic substance GO:0010033 284 0.123
Human Rat
positive regulation of cell proliferation GO:0008284 47 0.122
Mouse Rat
positive regulation of apoptotic process GO:0043065 47 0.122
Rat
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.122
Human
organelle fission GO:0048285 340 0.121
response to wounding GO:0009611 94 0.120
gland development GO:0048732 191 0.119
developmental cell growth GO:0048588 52 0.119
r7 cell differentiation GO:0045466 43 0.118
regulation of response to stress GO:0080134 200 0.117
regulation of epithelial cell proliferation GO:0050678 4 0.115
mitotic cell cycle phase transition GO:0044772 138 0.114
response to other organism GO:0051707 293 0.114
regulation of cellular component biogenesis GO:0044087 201 0.114
cell proliferation GO:0008283 299 0.113
Mouse Rat
blood circulation GO:0008015 26 0.113
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.113
embryonic pattern specification GO:0009880 174 0.112
lipid homeostasis GO:0055088 33 0.110
chorion containing eggshell formation GO:0007304 105 0.110
cellular response to inorganic substance GO:0071241 8 0.110
Mouse
positive regulation of protein modification process GO:0031401 58 0.108
Mouse
regulation of bmp signaling pathway GO:0030510 23 0.108
cellular response to chemical stimulus GO:0070887 199 0.107
Human Mouse Rat
cation transport GO:0006812 110 0.106
regulation of growth GO:0040008 233 0.105
reproductive system development GO:0061458 74 0.105
Mouse
regulation of cellular localization GO:0060341 136 0.104
positive regulation of developmental process GO:0051094 143 0.104
Mouse
negative regulation of nervous system development GO:0051961 92 0.103
negative regulation of mapk cascade GO:0043409 23 0.100
developmental programmed cell death GO:0010623 138 0.100
negative regulation of cell cycle GO:0045786 116 0.100
regulation of cell cycle process GO:0010564 181 0.099
stress activated protein kinase signaling cascade GO:0031098 55 0.098
cellular macromolecular complex assembly GO:0034622 153 0.098
developmental growth GO:0048589 280 0.098
response to inorganic substance GO:0010035 44 0.098
Mouse Rat
head involution GO:0008258 35 0.097
protein transport GO:0015031 155 0.097
ras protein signal transduction GO:0007265 88 0.093
positive regulation of neuron differentiation GO:0045666 26 0.092
protein modification process GO:0036211 438 0.092
regulation of cellular ketone metabolic process GO:0010565 3 0.090
regulation of map kinase activity GO:0043405 17 0.090
regulation of mitotic cell cycle GO:0007346 190 0.088
regulation of notch signaling pathway GO:0008593 100 0.087
homeostatic process GO:0042592 199 0.087
defense response GO:0006952 300 0.086
positive regulation of cell death GO:0010942 69 0.086
Rat
response to organonitrogen compound GO:0010243 75 0.085
Rat
determination of dorsal ventral asymmetry GO:0048262 3 0.085
positive regulation of mapk cascade GO:0043410 63 0.085
dna replication GO:0006260 48 0.084
ion transport GO:0006811 145 0.082
cellular response to oxidative stress GO:0034599 28 0.081
Human
urogenital system development GO:0001655 72 0.081
negative regulation of phosphorus metabolic process GO:0010563 45 0.081
response to starvation GO:0042594 97 0.080
reactive oxygen species metabolic process GO:0072593 22 0.079
humoral immune response GO:0006959 117 0.079
post embryonic appendage morphogenesis GO:0035120 385 0.077
negative regulation of protein metabolic process GO:0051248 85 0.077
response to biotic stimulus GO:0009607 294 0.077
regulation of cell migration GO:0030334 22 0.076
mitotic nuclear division GO:0007067 213 0.076
eggshell chorion assembly GO:0007306 66 0.076
regulation of cellular protein metabolic process GO:0032268 243 0.076
regulation of neuron differentiation GO:0045664 103 0.076
g1 s transition of mitotic cell cycle GO:0000082 31 0.075
rho protein signal transduction GO:0007266 14 0.075
cellular catabolic process GO:0044248 372 0.075
embryonic hindgut morphogenesis GO:0048619 48 0.074
regulation of multi organism process GO:0043900 131 0.074
circulatory system process GO:0003013 37 0.073
oxoacid metabolic process GO:0043436 103 0.073
axon guidance GO:0007411 233 0.073
regulation of synapse organization GO:0050807 110 0.073
immune system process GO:0002376 347 0.073
regulation of synapse assembly GO:0051963 94 0.072
lipid localization GO:0010876 54 0.072
dna integrity checkpoint GO:0031570 81 0.072
regulation of gliogenesis GO:0014013 11 0.071
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.071
cellular chemical homeostasis GO:0055082 40 0.071
response to carbohydrate GO:0009743 15 0.071
neuron death GO:0070997 27 0.070
defense response to fungus GO:0050832 48 0.070
segmentation GO:0035282 207 0.070
carboxylic acid metabolic process GO:0019752 92 0.070
hematopoietic progenitor cell differentiation GO:0002244 1 0.069
heart contraction GO:0060047 26 0.069
positive regulation of stem cell proliferation GO:2000648 8 0.069
regulation of response to oxidative stress GO:1902882 4 0.069
cellular protein complex assembly GO:0043623 71 0.068
body morphogenesis GO:0010171 2 0.068
dorsal appendage formation GO:0046843 47 0.068
germ line stem cell maintenance GO:0030718 50 0.068
eggshell formation GO:0030703 105 0.068
cellular amide metabolic process GO:0043603 80 0.066
response to metal ion GO:0010038 23 0.066
Mouse
jnk cascade GO:0007254 50 0.066
regulation of ras protein signal transduction GO:0046578 93 0.066
positive regulation of immune system process GO:0002684 68 0.066
Mouse
negative regulation of growth GO:0045926 84 0.066
neurological system process GO:0050877 358 0.065
Rat
epithelial cell differentiation GO:0030855 322 0.065
apoptotic signaling pathway GO:0097190 27 0.065
cellular component assembly involved in morphogenesis GO:0010927 151 0.065
oocyte differentiation GO:0009994 145 0.064
signal transduction in response to dna damage GO:0042770 3 0.064
negative regulation of autophagy GO:0010507 16 0.064
regulation of embryonic development GO:0045995 68 0.063
development of primary sexual characteristics GO:0045137 50 0.063
collateral sprouting GO:0048668 3 0.063
regulation of catabolic process GO:0009894 170 0.063
neuron projection guidance GO:0097485 241 0.062
activation of jun kinase activity GO:0007257 3 0.062
regulation of neuron apoptotic process GO:0043523 16 0.062
regulation of response to biotic stimulus GO:0002831 63 0.061
regulation of neuron death GO:1901214 26 0.061
cell cycle phase transition GO:0044770 140 0.061
response to nitrogen compound GO:1901698 90 0.061
Rat
aging GO:0007568 143 0.060
Rat
regulation of glial cell differentiation GO:0045685 1 0.060
negative regulation of cellular component organization GO:0051129 108 0.060
peptidyl amino acid modification GO:0018193 105 0.059
leg disc morphogenesis GO:0007478 80 0.059
epithelial cell development GO:0002064 274 0.058
skeletal muscle organ development GO:0060538 48 0.057
Mouse
wound healing GO:0042060 75 0.056
g protein coupled receptor signaling pathway GO:0007186 136 0.055
response to uv GO:0009411 24 0.055
regulation of vesicle mediated transport GO:0060627 59 0.055
axis specification GO:0009798 167 0.055
organonitrogen compound metabolic process GO:1901564 318 0.055
cellular response to organic substance GO:0071310 132 0.054
Human Rat
organic substance transport GO:0071702 257 0.053
regulation of synaptic transmission GO:0050804 69 0.053
regulation of dendrite development GO:0050773 37 0.053
positive regulation of hydrolase activity GO:0051345 78 0.053
regulation of cytoskeleton organization GO:0051493 89 0.053
protein complex biogenesis GO:0070271 201 0.053
dorsal closure GO:0007391 79 0.052
oxidation reduction process GO:0055114 123 0.052
germ cell migration GO:0008354 43 0.052
secretion by cell GO:0032940 101 0.052
cellular amino acid metabolic process GO:0006520 61 0.052
regulation of developmental growth GO:0048638 174 0.052
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.052
molting cycle GO:0042303 56 0.051
reproductive structure development GO:0048608 74 0.051
Mouse
initiation of dorsal closure GO:0007392 12 0.050
regulation of actin filament based process GO:0032970 42 0.050
nucleobase containing small molecule metabolic process GO:0055086 174 0.050
regulation of cellular amino acid metabolic process GO:0006521 0 0.050
nucleoside phosphate metabolic process GO:0006753 162 0.050
regulation of secretion by cell GO:1903530 39 0.049
negative regulation of hormone biosynthetic process GO:0032353 1 0.048
imaginal disc derived wing hair site selection GO:0035320 4 0.048
eye photoreceptor cell development GO:0042462 81 0.048
positive regulation of peptidase activity GO:0010952 29 0.048
organophosphate catabolic process GO:0046434 112 0.047
imaginal disc derived leg morphogenesis GO:0007480 80 0.047
muscle fiber development GO:0048747 12 0.047
negative regulation of phosphate metabolic process GO:0045936 45 0.046
positive regulation of cell development GO:0010720 61 0.046
single organism behavior GO:0044708 391 0.045
regulation of cell cycle g1 s phase transition GO:1902806 23 0.045
striated muscle cell differentiation GO:0051146 90 0.045
regulation of cell motility GO:2000145 23 0.045
response to ketone GO:1901654 34 0.045
Rat
blastoderm segmentation GO:0007350 159 0.045
regulation of stem cell proliferation GO:0072091 40 0.045
peptidyl threonine phosphorylation GO:0018107 2 0.045
glial cell development GO:0021782 27 0.044
positive regulation of cellular amine metabolic process GO:0033240 0 0.044
erbb signaling pathway GO:0038127 58 0.043
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.043
positive regulation of axon extension GO:0045773 2 0.043
negative regulation of ras protein signal transduction GO:0046580 13 0.042
axonogenesis GO:0007409 290 0.042
salivary gland development GO:0007431 162 0.042
positive regulation of multicellular organismal process GO:0051240 143 0.042
Mouse
peptide metabolic process GO:0006518 80 0.042
response to endogenous stimulus GO:0009719 119 0.042
Human Rat
determination of digestive tract left right asymmetry GO:0071907 6 0.042
negative regulation of programmed cell death GO:0043069 72 0.042
hemocyte differentiation GO:0042386 38 0.042
amine metabolic process GO:0009308 12 0.041
peptidyl tyrosine modification GO:0018212 24 0.041
photoreceptor cell development GO:0042461 96 0.041
purine nucleoside triphosphate catabolic process GO:0009146 108 0.041
neuroblast proliferation GO:0007405 74 0.040
maintenance of location GO:0051235 73 0.040
regulation of nucleotide metabolic process GO:0006140 62 0.040
dorsal closure elongation of leading edge cells GO:0007394 10 0.040
regulation of secretion GO:0051046 44 0.039
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.039
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.039
negative regulation of mitotic cell cycle GO:0045930 109 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.038
regulation of jun kinase activity GO:0043506 8 0.038
negative regulation of developmental growth GO:0048640 64 0.038
multi multicellular organism process GO:0044706 123 0.038
Rat
respiratory system development GO:0060541 213 0.037
regulation of hemocyte differentiation GO:0045610 22 0.037
regulation of cellular response to growth factor stimulus GO:0090287 13 0.037
dorsal ventral pattern formation GO:0009953 133 0.037
neuron maturation GO:0042551 31 0.037
response to transforming growth factor beta GO:0071559 18 0.036
Human
dorsal closure spreading of leading edge cells GO:0007395 4 0.036
cardiovascular system development GO:0072358 82 0.036
Mouse
protein targeting to nucleus GO:0044744 51 0.036
regulation of insulin secretion GO:0050796 5 0.036
anterior posterior axis specification GO:0009948 109 0.036
organic acid metabolic process GO:0006082 103 0.036
negative regulation of molecular function GO:0044092 51 0.035
neurotransmitter transport GO:0006836 37 0.035
tracheal outgrowth open tracheal system GO:0007426 18 0.035
organic hydroxy compound metabolic process GO:1901615 83 0.035
positive regulation of proteolysis GO:0045862 52 0.035
regulation of purine nucleotide metabolic process GO:1900542 62 0.035
pathway restricted smad protein phosphorylation GO:0060389 1 0.035
embryonic digestive tract development GO:0048566 5 0.034
purine nucleotide catabolic process GO:0006195 109 0.034
protein import GO:0017038 55 0.034
formation of anatomical boundary GO:0048859 37 0.034
secretion GO:0046903 109 0.034
imaginal disc fusion GO:0046528 19 0.034
multicellular organismal reproductive behavior GO:0033057 110 0.034
negative regulation of cell development GO:0010721 62 0.033
regulation of cell cycle phase transition GO:1901987 130 0.033
phagocytosis GO:0006909 215 0.033
antimicrobial humoral response GO:0019730 99 0.033
nucleotide catabolic process GO:0009166 109 0.033
hemocyte migration GO:0035099 19 0.033
regulation of immune response GO:0050776 118 0.033
smad protein import into nucleus GO:0007184 11 0.033
striated muscle tissue development GO:0014706 27 0.032
Mouse
reproductive behavior GO:0019098 122 0.032
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.032
regulation of cellular amine metabolic process GO:0033238 3 0.032
negative regulation of cell size GO:0045792 19 0.032
unidimensional cell growth GO:0009826 15 0.032

kay disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.133
musculoskeletal system disease DOID:17 0 0.133
nervous system disease DOID:863 0 0.076