Drosophila melanogaster

117 known processes

gus (Dmel_CG2944)

gustavus

(Aliases: GUSTAVUS,A11,CG2946,CG2944,i25,Gus,GUS,dmSSB4,Dmel\CG2944)

gus biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte development GO:0048599 124 0.777
protein complex assembly GO:0006461 200 0.761
localization of cell GO:0051674 257 0.718
appendage development GO:0048736 401 0.642
oocyte axis specification GO:0007309 108 0.538
oocyte differentiation GO:0009994 145 0.486
macromolecular complex assembly GO:0065003 256 0.477
oocyte anterior posterior axis specification GO:0007314 72 0.428
imaginal disc derived appendage development GO:0048737 399 0.407
cell division GO:0051301 248 0.400
anterior posterior axis specification GO:0009948 109 0.394
negative regulation of cellular component organization GO:0051129 108 0.289
Fly
oocyte construction GO:0007308 112 0.272
growth GO:0040007 359 0.248
Fly
wing disc morphogenesis GO:0007472 344 0.247
establishment of localization in cell GO:0051649 402 0.241
vesicle mediated transport GO:0016192 381 0.239
positive regulation of phosphorus metabolic process GO:0010562 139 0.232
cellular protein modification process GO:0006464 438 0.226
regulation of cellular component biogenesis GO:0044087 201 0.225
Fly
protein complex biogenesis GO:0070271 201 0.218
single organism carbohydrate metabolic process GO:0044723 72 0.215
cellular catabolic process GO:0044248 372 0.215
regulation of growth GO:0040008 233 0.212
Fly
intracellular signal transduction GO:0035556 300 0.211
negative regulation of cell cycle GO:0045786 116 0.195
protein modification process GO:0036211 438 0.193
endocytosis GO:0006897 310 0.183
cell maturation GO:0048469 144 0.182
muscle structure development GO:0061061 224 0.181
regulation of cell cycle GO:0051726 291 0.174
positive regulation of phosphate metabolic process GO:0045937 139 0.153
regulation of molecular function GO:0065009 217 0.150
cellular macromolecule catabolic process GO:0044265 136 0.147
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.139
negative regulation of signaling GO:0023057 219 0.138
imaginal disc derived wing morphogenesis GO:0007476 337 0.127
organic cyclic compound catabolic process GO:1901361 168 0.126
organonitrogen compound metabolic process GO:1901564 318 0.123
response to carbon dioxide GO:0010037 4 0.123
regulation of catalytic activity GO:0050790 185 0.122
mitotic cell cycle checkpoint GO:0007093 88 0.120
phosphorylation GO:0016310 294 0.119
cellular macromolecular complex assembly GO:0034622 153 0.119
oocyte maturation GO:0001556 3 0.118
positive regulation of cellular protein metabolic process GO:0032270 118 0.116
cellular response to dna damage stimulus GO:0006974 223 0.109
appendage morphogenesis GO:0035107 397 0.108
regulation of phosphate metabolic process GO:0019220 210 0.104
regulation of localization GO:0032879 275 0.103
epithelial cell development GO:0002064 274 0.103
rna localization GO:0006403 115 0.101
regulation of cellular protein metabolic process GO:0032268 243 0.099
regionalization GO:0003002 416 0.098
muscle cell differentiation GO:0042692 103 0.098
mitotic spindle organization GO:0007052 220 0.096
nucleobase containing compound catabolic process GO:0034655 165 0.093
pole plasm assembly GO:0007315 61 0.091
spindle organization GO:0007051 253 0.089
negative regulation of cell communication GO:0010648 223 0.080
embryonic axis specification GO:0000578 107 0.079
organelle assembly GO:0070925 198 0.079
negative regulation of cell cycle phase transition GO:1901988 103 0.077
post embryonic appendage morphogenesis GO:0035120 385 0.075
regulation of cell cycle phase transition GO:1901987 130 0.073
organic substance catabolic process GO:1901575 308 0.071
body morphogenesis GO:0010171 2 0.071
regulation of multi organism process GO:0043900 131 0.070
carboxylic acid metabolic process GO:0019752 92 0.070
small molecule metabolic process GO:0044281 305 0.069
synapse organization GO:0050808 196 0.069
Fly
cellular response to chemical stimulus GO:0070887 199 0.069
programmed cell death GO:0012501 257 0.066
small gtpase mediated signal transduction GO:0007264 88 0.065
regulation of kinase activity GO:0043549 53 0.065
regulation of phosphorus metabolic process GO:0051174 210 0.062
regulation of actin filament based process GO:0032970 42 0.062
regulation of transport GO:0051049 181 0.062
negative regulation of cellular biosynthetic process GO:0031327 277 0.061
synaptic transmission GO:0007268 288 0.061
Fly
regulation of cellular localization GO:0060341 136 0.059
meiotic cell cycle GO:0051321 171 0.059
catabolic process GO:0009056 409 0.054
secretion by cell GO:0032940 101 0.054
positive regulation of macromolecule metabolic process GO:0010604 405 0.053
carbohydrate derivative biosynthetic process GO:1901137 85 0.052
muscle cell development GO:0055001 50 0.051
oxoacid metabolic process GO:0043436 103 0.051
positive regulation of rna metabolic process GO:0051254 271 0.050
positive regulation of protein metabolic process GO:0051247 128 0.050
reproductive structure development GO:0048608 74 0.050
regulation of synapse structure and activity GO:0050803 128 0.049
Fly
response to biotic stimulus GO:0009607 294 0.048
protein catabolic process GO:0030163 101 0.047
organic acid metabolic process GO:0006082 103 0.047
developmental growth GO:0048589 280 0.046
Fly
regulation of hemocyte proliferation GO:0035206 37 0.046
eye development GO:0001654 323 0.043
positive regulation of catalytic activity GO:0043085 118 0.041
embryonic cleavage GO:0040016 5 0.040
positive regulation of gene expression GO:0010628 290 0.039
ovarian follicle cell development GO:0030707 248 0.038
negative regulation of mitotic cell cycle GO:0045930 109 0.038
cell migration GO:0016477 238 0.037
phagocytosis GO:0006909 215 0.037
response to external biotic stimulus GO:0043207 293 0.036
positive regulation of molecular function GO:0044093 136 0.036
regulation of pole plasm oskar mrna localization GO:0007317 27 0.035
negative regulation of response to stimulus GO:0048585 258 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
cellularization GO:0007349 90 0.034
chromosome segregation GO:0007059 157 0.034
gene silencing by rna GO:0031047 57 0.034
stem cell development GO:0048864 79 0.034
cell cycle phase transition GO:0044770 140 0.034
sex differentiation GO:0007548 81 0.034
tissue morphogenesis GO:0048729 297 0.033
chorion containing eggshell formation GO:0007304 105 0.032
single organism intracellular transport GO:1902582 207 0.031
ras protein signal transduction GO:0007265 88 0.030
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.030
organelle fission GO:0048285 340 0.030
synaptic growth at neuromuscular junction GO:0051124 119 0.030
Fly
positive regulation of cell migration GO:0030335 2 0.030
regulation of protein metabolic process GO:0051246 256 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
carbohydrate metabolic process GO:0005975 82 0.029
regulation of actin filament polymerization GO:0030833 25 0.029
ribonucleoprotein complex assembly GO:0022618 23 0.028
posttranscriptional regulation of gene expression GO:0010608 145 0.028
larval development GO:0002164 104 0.028
blood circulation GO:0008015 26 0.028
axis specification GO:0009798 167 0.028
gonad development GO:0008406 50 0.028
anterior posterior pattern specification GO:0009952 136 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
translation GO:0006412 69 0.027
regulation of protein modification process GO:0031399 112 0.027
carbohydrate biosynthetic process GO:0016051 17 0.027
response to oxygen containing compound GO:1901700 200 0.026
pole cell development GO:0007277 26 0.026
ribonucleoprotein complex subunit organization GO:0071826 28 0.026
gene silencing GO:0016458 138 0.026
mapk cascade GO:0000165 107 0.025
positive regulation of phosphorylation GO:0042327 87 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
segmentation GO:0035282 207 0.025
asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060 2 0.025
meiotic cell cycle process GO:1903046 132 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.024
protein polymerization GO:0051258 42 0.023
internal peptidyl lysine acetylation GO:0018393 38 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
ribonucleoprotein complex biogenesis GO:0022613 31 0.023
biological adhesion GO:0022610 138 0.023
actin filament organization GO:0007015 126 0.023
protein phosphorylation GO:0006468 169 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
regulation of reproductive process GO:2000241 54 0.022
mitotic cell cycle phase transition GO:0044772 138 0.022
dorsal closure leading edge cell differentiation GO:0046663 2 0.022
pronuclear migration GO:0035046 4 0.021
maintenance of location GO:0051235 73 0.021
circulatory system development GO:0072359 82 0.020
regulation of synapse assembly GO:0051963 94 0.020
Fly
regulation of cell cycle process GO:0010564 181 0.020
sensory organ morphogenesis GO:0090596 260 0.020
positive regulation of protein modification process GO:0031401 58 0.020
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.020
negative regulation of programmed cell death GO:0043069 72 0.019
stress granule disassembly GO:0035617 1 0.019
regulation of programmed cell death GO:0043067 152 0.019
regulation of organelle organization GO:0033043 196 0.019
establishment or maintenance of cell polarity GO:0007163 167 0.019
cellular response to carbon dioxide GO:0071244 2 0.019
positive regulation of signal transduction GO:0009967 223 0.019
positive regulation of transport GO:0051050 92 0.019
aromatic compound catabolic process GO:0019439 166 0.019
single organism cell adhesion GO:0098602 47 0.019
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.018
spermatogenesis GO:0007283 200 0.018
organic substance transport GO:0071702 257 0.018
cell death GO:0008219 279 0.018
negative regulation of eye photoreceptor cell development GO:0042480 3 0.018
regulation of phosphatase activity GO:0010921 3 0.018
nucleus organization GO:0006997 45 0.018
regulation of cytoplasmic transport GO:1903649 47 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
chemotaxis GO:0006935 249 0.017
positive regulation of immune response GO:0050778 63 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
Fly
death GO:0016265 284 0.017
nuclear export GO:0051168 24 0.017
immune response GO:0006955 246 0.016
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902166 1 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
single organismal cell cell adhesion GO:0016337 45 0.016
circulatory system process GO:0003013 37 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
negative regulation of phosphatase activity GO:0010923 3 0.015
response to ethanol GO:0045471 59 0.015
intracellular mrna localization GO:0008298 66 0.015
nitric oxide metabolic process GO:0046209 1 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
negative regulation of apoptotic process GO:0043066 63 0.015
cell cell junction organization GO:0045216 55 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
nucleus localization GO:0051647 34 0.014
dna damage checkpoint GO:0000077 78 0.014
immune system process GO:0002376 347 0.014
gland development GO:0048732 191 0.014
compound eye morphogenesis GO:0001745 249 0.014
response to other organism GO:0051707 293 0.014
positive regulation of feeding behavior GO:2000253 8 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
reactive oxygen species biosynthetic process GO:1903409 0 0.013
oocyte morphogenesis GO:0048601 3 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.013
cardiovascular system development GO:0072358 82 0.013
response to abiotic stimulus GO:0009628 341 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336 3 0.013
reproductive system development GO:0061458 74 0.012
juvenile hormone mediated signaling pathway GO:0035626 3 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
lipid metabolic process GO:0006629 121 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
cell cycle arrest GO:0007050 4 0.012
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.012
regulation of meiotic cell cycle GO:0051445 9 0.012
forebrain development GO:0030900 2 0.012
regulation of cell migration GO:0030334 22 0.012
estrogen metabolic process GO:0008210 1 0.011
response to nitrogen compound GO:1901698 90 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of phosphorylation GO:0042325 147 0.011
cellular protein complex assembly GO:0043623 71 0.011
embryonic morphogenesis GO:0048598 206 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
neuron projection guidance GO:0097485 241 0.011
positive regulation of multi organism process GO:0043902 40 0.011
regulation of transferase activity GO:0051338 58 0.011
negative regulation of nervous system development GO:0051961 92 0.011
Fly
negative regulation of cell death GO:0060548 81 0.011
secretion GO:0046903 109 0.011
golgi organization GO:0007030 66 0.011
regulation of cell death GO:0010941 173 0.011
intermediate filament cytoskeleton organization GO:0045104 1 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
development of primary sexual characteristics GO:0045137 50 0.010
regulation of multicellular organismal development GO:2000026 414 0.010
Fly
pole cell formation GO:0007279 19 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010
pole plasm oskar mrna localization GO:0045451 46 0.010
regulation of protein kinase activity GO:0045859 51 0.010
glycoprotein metabolic process GO:0009100 41 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
diterpenoid biosynthetic process GO:0016102 1 0.010
regulation of rac gtpase activity GO:0032314 1 0.010

gus disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
reproductive organ cancer DOID:193 0 0.012
ovarian cancer DOID:2394 0 0.012
female reproductive organ cancer DOID:120 0 0.012
organ system cancer DOID:0050686 0 0.012