Drosophila melanogaster

250 known processes

dlg1 (Dmel_CG1725)

discs large 1

(Aliases: anon-WO03040301.258,Dlg,SAP97,PSD95,d. lg.-1,CPD,misb,DlgA,l(1)G0276,l(1)L11,Drodlg,l(1)d.lg-1,dlg,l(1)10Bf,anon-EST:Posey93,Dlg-A,l(1)lpr-2,CG1725,Dmel\CG1725,Dlg1,DLG,anon-WO03040301.268,dlg-A,anon-WO03040301.260,dlgS97,l(1)G0456,l(1)dlg-1,l(1)G19,l(1)dlg,Discs-large,11,l(1)discs large,l(1)bwn,DLG-A,l(1)dlg1,dlgA,l(1)l.pr.-2,CG1730,l(1)G0342,dlg-1,l(1)d.lg.-1)

dlg1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotory behavior GO:0007626 176 0.997
single organism behavior GO:0044708 391 0.994
ovarian follicle cell migration GO:0007297 121 0.978
neuron neuron synaptic transmission GO:0007270 14 0.977
response to endogenous stimulus GO:0009719 119 0.938
epithelial cell development GO:0002064 274 0.936
neurological system process GO:0050877 358 0.912
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.897
adult locomotory behavior GO:0008344 76 0.882
cell division GO:0051301 248 0.877
ovarian follicle cell development GO:0030707 248 0.860
segmentation GO:0035282 207 0.851
negative regulation of signal transduction GO:0009968 206 0.849
Mouse
border follicle cell migration GO:0007298 113 0.823
establishment of localization in cell GO:0051649 402 0.781
establishment or maintenance of cell polarity GO:0007163 167 0.778
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.777
macromolecular complex assembly GO:0065003 256 0.776
Human Mouse
synaptic transmission GO:0007268 288 0.775
secretion by cell GO:0032940 101 0.764
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.741
head development GO:0060322 135 0.737
cell junction organization GO:0034330 57 0.715
Human Worm
regulation of synaptic transmission GO:0050804 69 0.709
Mouse Rat
regulation of cellular component biogenesis GO:0044087 201 0.699
regulation of cellular localization GO:0060341 136 0.692
Human
synaptic vesicle endocytosis GO:0048488 28 0.653
Mouse
neurotransmitter transport GO:0006836 37 0.609
negative regulation of cellular biosynthetic process GO:0031327 277 0.570
oocyte construction GO:0007308 112 0.566
appendage development GO:0048736 401 0.564
protein catabolic process GO:0030163 101 0.562
epithelial cell migration GO:0010631 148 0.546
negative regulation of cell communication GO:0010648 223 0.529
Mouse
learning or memory GO:0007611 141 0.517
organelle localization GO:0051640 148 0.513
transcription from rna polymerase ii promoter GO:0006366 368 0.507
cell proliferation GO:0008283 299 0.447
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.444
organ growth GO:0035265 56 0.444
semaphorin plexin signaling pathway GO:0071526 4 0.443
embryonic pattern specification GO:0009880 174 0.441
ameboidal type cell migration GO:0001667 151 0.421
imaginal disc derived appendage morphogenesis GO:0035114 395 0.421
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.419
Mouse
defense response GO:0006952 300 0.415
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.414
adult behavior GO:0030534 137 0.412
synapse organization GO:0050808 196 0.409
tissue migration GO:0090130 155 0.409
regulation of phosphate metabolic process GO:0019220 210 0.403
Human Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.403
epidermis development GO:0008544 65 0.400
regulation of cell morphogenesis GO:0022604 163 0.400
neurotransmitter secretion GO:0007269 35 0.397
stem cell division GO:0017145 69 0.394
blastoderm segmentation GO:0007350 159 0.392
positive regulation of secretion GO:0051047 22 0.376
negative regulation of cellular metabolic process GO:0031324 382 0.369
developmental growth GO:0048589 280 0.367
dorsal closure GO:0007391 79 0.365
axonogenesis GO:0007409 290 0.363
imaginal disc growth GO:0007446 37 0.359
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.357
regulation of organelle organization GO:0033043 196 0.357
Mouse
negative regulation of response to stimulus GO:0048585 258 0.350
Mouse
germarium derived egg chamber formation GO:0007293 101 0.348
regulation of tube architecture open tracheal system GO:0035152 68 0.347
tissue morphogenesis GO:0048729 297 0.346
regulation of neuromuscular synaptic transmission GO:1900073 15 0.340
regulation of synapse structure and activity GO:0050803 128 0.333
regulation of cell cycle process GO:0010564 181 0.323
appendage morphogenesis GO:0035107 397 0.317
morphogenesis of an epithelium GO:0002009 276 0.311
compound eye photoreceptor cell differentiation GO:0001751 140 0.311
synaptic growth at neuromuscular junction GO:0051124 119 0.306
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.300
receptor clustering GO:0043113 3 0.300
Rat
axon development GO:0061564 297 0.294
regulation of cell projection organization GO:0031344 92 0.287
positive regulation of signaling GO:0023056 243 0.284
Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.271
cellular amino acid metabolic process GO:0006520 61 0.266
regulation of intracellular signal transduction GO:1902531 236 0.265
r3 r4 cell fate commitment GO:0007464 10 0.264
regulation of localization GO:0032879 275 0.257
Human Rat
chemotaxis GO:0006935 249 0.250
regulation of secretion GO:0051046 44 0.249
regulation of multicellular organismal development GO:2000026 414 0.236
positive regulation of cell communication GO:0010647 250 0.233
Rat
embryonic morphogenesis GO:0048598 206 0.233
Mouse
neuromuscular synaptic transmission GO:0007274 67 0.227
regulation of phosphorylation GO:0042325 147 0.225
Mouse
imaginal disc derived appendage development GO:0048737 399 0.222
skin development GO:0043588 65 0.220
organelle fission GO:0048285 340 0.213
synaptic vesicle localization GO:0097479 53 0.212
Mouse
positive regulation of synapse assembly GO:0051965 29 0.209
growth GO:0040007 359 0.204
protein localization GO:0008104 284 0.204
negative regulation of rna metabolic process GO:0051253 251 0.201
central nervous system development GO:0007417 201 0.197
negative regulation of signaling GO:0023057 219 0.194
Mouse
positive regulation of response to stimulus GO:0048584 323 0.192
cellular protein modification process GO:0006464 438 0.189
Mouse
cell maturation GO:0048469 144 0.189
axis specification GO:0009798 167 0.187
vesicle mediated transport GO:0016192 381 0.187
Mouse Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.183
cell motility GO:0048870 251 0.177
negative regulation of biosynthetic process GO:0009890 277 0.174
compound eye photoreceptor fate commitment GO:0001752 36 0.174
larval development GO:0002164 104 0.173
Worm
negative regulation of cellular component organization GO:0051129 108 0.173
Rat
chemical homeostasis GO:0048878 92 0.173
Rat
regulation of developmental growth GO:0048638 174 0.172
post embryonic appendage morphogenesis GO:0035120 385 0.160
protein modification process GO:0036211 438 0.159
Mouse
positive regulation of proteolysis GO:0045862 52 0.158
single organismal cell cell adhesion GO:0016337 45 0.150
Human
epithelium migration GO:0090132 148 0.147
establishment of ommatidial planar polarity GO:0042067 49 0.141
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.138
Mouse
photoreceptor cell differentiation GO:0046530 170 0.138
regulation of neurotransmitter levels GO:0001505 38 0.137
regulation of mitotic cell cycle GO:0007346 190 0.136
Human
dna metabolic process GO:0006259 227 0.134
cognition GO:0050890 141 0.133
open tracheal system development GO:0007424 204 0.130
negative regulation of gene expression GO:0010629 387 0.128
enzyme linked receptor protein signaling pathway GO:0007167 179 0.127
regulation of neuron differentiation GO:0045664 103 0.126
positive regulation of synaptic transmission GO:0050806 15 0.123
Rat
single organism cell adhesion GO:0098602 47 0.122
Human
male courtship behavior GO:0008049 63 0.120
establishment of epithelial cell planar polarity GO:0090163 4 0.120
regulation of transport GO:0051049 181 0.119
Human Rat
brain development GO:0007420 120 0.119
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.117
multi organism behavior GO:0051705 175 0.116
establishment of apical basal cell polarity GO:0035089 12 0.116
regulation of cell differentiation GO:0045595 302 0.115
asymmetric protein localization GO:0008105 33 0.114
regulation of cell proliferation GO:0042127 163 0.113
Mouse
asymmetric neuroblast division GO:0055059 33 0.110
regulation of cell division GO:0051302 72 0.110
eye morphogenesis GO:0048592 260 0.109
synaptic vesicle recycling GO:0036465 28 0.108
Mouse
neuroblast proliferation GO:0007405 74 0.106
immune system process GO:0002376 347 0.105
Mouse
circadian rhythm GO:0007623 105 0.104
positive regulation of phosphorus metabolic process GO:0010562 139 0.104
Mouse
taxis GO:0042330 304 0.103
regulation of epithelial cell proliferation GO:0050678 4 0.102
Mouse
catabolic process GO:0009056 409 0.101
regulation of secretion by cell GO:1903530 39 0.099
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.099
reproductive behavior GO:0019098 122 0.099
circulatory system development GO:0072359 82 0.097
muscle organ development GO:0007517 127 0.097
morphogenesis of embryonic epithelium GO:0016331 94 0.096
negative regulation of hormone biosynthetic process GO:0032353 1 0.095
oocyte differentiation GO:0009994 145 0.093
establishment of organelle localization GO:0051656 122 0.092
protein complex biogenesis GO:0070271 201 0.091
Human Mouse
immune system development GO:0002520 57 0.091
muscle system process GO:0003012 21 0.091
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.090
Mouse
regulation of notch signaling pathway GO:0008593 100 0.090
cell cell junction organization GO:0045216 55 0.089
Human Worm
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.089
cellular response to chemical stimulus GO:0070887 199 0.088
cellular macromolecular complex assembly GO:0034622 153 0.088
Mouse
purine nucleotide metabolic process GO:0006163 146 0.088
developmental maturation GO:0021700 172 0.088
heart process GO:0003015 37 0.087
single organism cellular localization GO:1902580 180 0.087
regulation of actin filament based process GO:0032970 42 0.087
Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.085
regulation of neuron projection development GO:0010975 69 0.085
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.084
negative regulation of cell development GO:0010721 62 0.083
protein transport GO:0015031 155 0.083
digestive system development GO:0055123 149 0.083
stem cell proliferation GO:0072089 88 0.080
carbohydrate derivative metabolic process GO:1901135 217 0.079
regulation of programmed cell death GO:0043067 152 0.079
positive regulation of biosynthetic process GO:0009891 316 0.079
cell cell signaling involved in cell fate commitment GO:0045168 210 0.077
photoreceptor cell fate commitment GO:0046552 41 0.077
multicellular organismal reproductive behavior GO:0033057 110 0.077
negative regulation of cell proliferation GO:0008285 69 0.077
Mouse
cellular protein catabolic process GO:0044257 83 0.075
nucleoside phosphate metabolic process GO:0006753 162 0.075
membrane depolarization GO:0051899 4 0.072
Rat
notch signaling pathway GO:0007219 120 0.071
synaptic transmission glutamatergic GO:0035249 7 0.070
smoothened signaling pathway GO:0007224 49 0.070
carbohydrate derivative biosynthetic process GO:1901137 85 0.069
regulation of vesicle mediated transport GO:0060627 59 0.069
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.068
intraspecies interaction between organisms GO:0051703 4 0.068
Mouse
regulation of cell death GO:0010941 173 0.068
regulation of synaptic transmission glutamatergic GO:0051966 5 0.067
single organism carbohydrate metabolic process GO:0044723 72 0.065
endomembrane system organization GO:0010256 119 0.065
Human
rhythmic process GO:0048511 106 0.065
negative regulation of epithelial cell proliferation GO:0050680 4 0.065
Mouse
tripartite regional subdivision GO:0007351 103 0.065
nucleoside triphosphate metabolic process GO:0009141 120 0.064
organic substance transport GO:0071702 257 0.063
epithelial cell differentiation GO:0030855 322 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
cellular catabolic process GO:0044248 372 0.061
protein complex assembly GO:0006461 200 0.061
Human Mouse
asymmetric stem cell division GO:0098722 49 0.060
ribonucleoside metabolic process GO:0009119 127 0.060
wing disc morphogenesis GO:0007472 344 0.060
organic substance catabolic process GO:1901575 308 0.060
nucleoside phosphate catabolic process GO:1901292 110 0.059
non sensory hair organization GO:0035316 47 0.059
regulation of system process GO:0044057 36 0.059
oocyte axis specification GO:0007309 108 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
response to alcohol GO:0097305 95 0.057
mesenchymal cell development GO:0014031 1 0.057
organophosphate metabolic process GO:0019637 195 0.057
tube development GO:0035295 244 0.057
Mouse
metal ion homeostasis GO:0055065 44 0.056
Rat
negative regulation of nervous system development GO:0051961 92 0.056
establishment of epithelial cell apical basal polarity GO:0045198 10 0.055
secretion GO:0046903 109 0.055
regulation of hydrolase activity GO:0051336 97 0.055
Human
regulation of immune system process GO:0002682 176 0.055
Mouse
striated muscle contraction GO:0006941 5 0.055
oocyte development GO:0048599 124 0.054
response to organic cyclic compound GO:0014070 89 0.054
actin filament based process GO:0030029 220 0.053
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.053
Mouse
neuron fate commitment GO:0048663 50 0.053
phosphorylation GO:0016310 294 0.052
Mouse
regulation of catabolic process GO:0009894 170 0.052
epithelial cell proliferation GO:0050673 15 0.052
Human Mouse
cell adhesion GO:0007155 136 0.050
Human Rat
localization of cell GO:0051674 257 0.050
morphogenesis of follicular epithelium GO:0016333 36 0.050
negative regulation of growth GO:0045926 84 0.050
cation homeostasis GO:0055080 51 0.049
Rat
synaptic vesicle transport GO:0048489 50 0.049
Mouse
response to abiotic stimulus GO:0009628 341 0.048
developmental growth involved in morphogenesis GO:0060560 65 0.048
regulation of cell cycle GO:0051726 291 0.047
Human
neuron recognition GO:0008038 101 0.047
cell cell junction assembly GO:0007043 38 0.047
Human Worm
sister chromatid segregation GO:0000819 92 0.047
regulation of molecular function GO:0065009 217 0.046
Human Mouse Rat
positive regulation of signal transduction GO:0009967 223 0.046
ubiquitin dependent protein catabolic process GO:0006511 78 0.046
regulation of actin cytoskeleton organization GO:0032956 42 0.046
Mouse
cation transport GO:0006812 110 0.046
Human Rat
apical junction assembly GO:0043297 32 0.045
Human Worm
regulation of organ growth GO:0046620 42 0.044
blood circulation GO:0008015 26 0.044
retina development in camera type eye GO:0060041 4 0.043
metal ion transport GO:0030001 74 0.042
Human Rat
positive regulation of protein catabolic process GO:0045732 34 0.042
cell recognition GO:0008037 102 0.041
Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
synapse assembly GO:0007416 143 0.041
r3 r4 cell differentiation GO:0048056 12 0.041
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.041
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.041
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.040
Human Mouse
regulation of imaginal disc growth GO:0045570 26 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
intracellular signal transduction GO:0035556 300 0.040
regulation of blood circulation GO:1903522 21 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.039
regulation of cellular catabolic process GO:0031329 157 0.038
sensory perception GO:0007600 196 0.038
Mouse
regulation of protein catabolic process GO:0042176 55 0.038
establishment of protein localization GO:0045184 163 0.038
Human
regulation of multi organism process GO:0043900 131 0.037
immune response GO:0006955 246 0.037
Mouse
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator GO:1902254 1 0.037
instar larval development GO:0002168 55 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
cellular response to organic substance GO:0071310 132 0.037
establishment of monopolar cell polarity GO:0061162 15 0.037
regulation of cell growth GO:0001558 43 0.036
cell migration GO:0016477 238 0.036
determination of adult lifespan GO:0008340 137 0.036
regulation of proteasomal protein catabolic process GO:0061136 39 0.036
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.036
compound eye morphogenesis GO:0001745 249 0.036
circulatory system process GO:0003013 37 0.036
establishment of spindle orientation GO:0051294 18 0.036
proteasomal protein catabolic process GO:0010498 59 0.036
regulation of cellular amino acid metabolic process GO:0006521 0 0.036
regulation of jnk cascade GO:0046328 40 0.035
positive regulation of molecular function GO:0044093 136 0.035
Mouse
eye development GO:0001654 323 0.035
Mouse
regulation of catalytic activity GO:0050790 185 0.035
Human Mouse
negative regulation of developmental process GO:0051093 201 0.035
cuticle development GO:0042335 86 0.034
cell fate commitment involved in pattern specification GO:0060581 31 0.034
regulation of growth GO:0040008 233 0.033
regulation of protein metabolic process GO:0051246 256 0.033
Mouse
nucleoside metabolic process GO:0009116 127 0.033
response to oxygen containing compound GO:1901700 200 0.033
regulation of protein phosphorylation GO:0001932 64 0.032
Mouse
regulation of cellular response to stress GO:0080135 89 0.032
biological adhesion GO:0022610 138 0.031
Human Rat
ribonucleotide metabolic process GO:0009259 145 0.031
regulation of cellular response to growth factor stimulus GO:0090287 13 0.031
response to decreased oxygen levels GO:0036293 58 0.030
regulation of cellular component size GO:0032535 98 0.030
Mouse
small molecule metabolic process GO:0044281 305 0.029
macromolecule catabolic process GO:0009057 161 0.029
eye photoreceptor cell fate commitment GO:0042706 37 0.029
negative regulation of intracellular signal transduction GO:1902532 57 0.029
Mouse
endocytosis GO:0006897 310 0.029
Mouse Rat
reproductive structure development GO:0048608 74 0.028
Mouse
actin cytoskeleton organization GO:0030036 206 0.028
Human Mouse
regulation of nucleotide metabolic process GO:0006140 62 0.028
zonula adherens assembly GO:0045186 6 0.028
Worm
synaptic vesicle exocytosis GO:0016079 16 0.027
regulation of neurotransmitter secretion GO:0046928 14 0.027
positive regulation of cell death GO:0010942 69 0.027
chromosome segregation GO:0007059 157 0.027
establishment of cell polarity GO:0030010 40 0.027
stem cell development GO:0048864 79 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
forebrain development GO:0030900 2 0.027
modification dependent protein catabolic process GO:0019941 78 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.026
negative regulation of imaginal disc growth GO:0045571 8 0.026
positive regulation of cell projection organization GO:0031346 29 0.025
heart development GO:0007507 82 0.025
establishment of mitotic spindle orientation GO:0000132 13 0.025
regulation of membrane potential GO:0042391 35 0.025
Human Mouse Rat
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.025
regulation of cell development GO:0060284 215 0.025
periodic partitioning GO:0007365 29 0.025
mushroom body development GO:0016319 70 0.025
regulation of rac gtpase activity GO:0032314 1 0.024
nuclear division GO:0000280 332 0.024
regionalization GO:0003002 416 0.024
negative regulation of dendrite morphogenesis GO:0050774 2 0.024
response to hypoxia GO:0001666 53 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
regulation of actin polymerization or depolymerization GO:0008064 27 0.023
Mouse
regulation of synapse assembly GO:0051963 94 0.023
eye antennal disc morphogenesis GO:0007455 34 0.023
amine metabolic process GO:0009308 12 0.023
neuroblast division GO:0055057 35 0.023
positive regulation of catabolic process GO:0009896 105 0.023
cuticle pattern formation GO:0035017 27 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
anterior posterior axis specification GO:0009948 109 0.022
adherens junction organization GO:0034332 27 0.022
Worm
heart morphogenesis GO:0003007 32 0.022
memory GO:0007613 94 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
nucleotide metabolic process GO:0009117 161 0.022
regulation of kinase activity GO:0043549 53 0.022
Mouse
regulation of neurogenesis GO:0050767 158 0.021
establishment of synaptic vesicle localization GO:0097480 50 0.021
Mouse
polarized epithelial cell differentiation GO:0030859 10 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
asymmetric cell division GO:0008356 37 0.021
hindgut morphogenesis GO:0007442 58 0.021
negative regulation of dendrite development GO:2000171 2 0.021
malpighian tubule development GO:0072002 64 0.020
camera type eye development GO:0043010 4 0.020
Mouse
axon guidance GO:0007411 233 0.020
specification of organ identity GO:0010092 3 0.020
regulation of cellular protein catabolic process GO:1903362 44 0.020
intracellular protein transport GO:0006886 104 0.020
oocyte anterior posterior axis specification GO:0007314 72 0.020
response to radiation GO:0009314 155 0.020
social behavior GO:0035176 4 0.020
Mouse
regulation of anatomical structure size GO:0090066 163 0.020
Mouse
regulation of response to stress GO:0080134 200 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
lateral inhibition GO:0046331 206 0.019
detection of stimulus GO:0051606 156 0.019
regulation of protein localization GO:0032880 76 0.019
Human Rat
positive regulation of cellular component organization GO:0051130 156 0.019
endoderm formation GO:0001706 3 0.019
regulation of circadian rhythm GO:0042752 49 0.019
striated muscle tissue development GO:0014706 27 0.019
mitotic nuclear division GO:0007067 213 0.019
positive regulation of cell proliferation GO:0008284 47 0.018
Mouse
cell fate specification GO:0001708 71 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
negative regulation of nucleotide metabolic process GO:0045980 4 0.018
circadian behavior GO:0048512 76 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
Human
central nervous system neuron differentiation GO:0021953 8 0.018
programmed cell death GO:0012501 257 0.018
mesenchymal cell differentiation GO:0048762 1 0.018
regulation of protein modification process GO:0031399 112 0.017
Mouse
purine containing compound metabolic process GO:0072521 155 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.017
meiotic nuclear envelope disassembly GO:0051078 2 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
cellular macromolecule localization GO:0070727 220 0.017
Human Rat
negative regulation of protein phosphorylation GO:0001933 17 0.017
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
epithelial tube morphogenesis GO:0060562 88 0.017
Mouse
nucleoside catabolic process GO:0009164 112 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
positive regulation of cell development GO:0010720 61 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.016
axonal fasciculation GO:0007413 12 0.016
eye antennal disc development GO:0035214 60 0.016
single organism biosynthetic process GO:0044711 206 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of dendrite morphogenesis GO:0048814 28 0.016
respiratory system development GO:0060541 213 0.016
response to organic substance GO:0010033 284 0.016
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.016
epidermal cell differentiation GO:0009913 51 0.016
anterior posterior axis specification follicular epithelium GO:0030714 2 0.016
exocytosis GO:0006887 28 0.016
neuron projection guidance GO:0097485 241 0.016
establishment of vesicle localization GO:0051650 51 0.015
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.015
kidney development GO:0001822 3 0.015
Mouse
jnk cascade GO:0007254 50 0.015
flight behavior GO:0007629 26 0.015
regulation of behavior GO:0050795 75 0.015
Mouse
carbohydrate metabolic process GO:0005975 82 0.015
regulation of phosphatase activity GO:0010921 3 0.015
Human
peptidyl threonine phosphorylation GO:0018107 2 0.015
somatic stem cell division GO:0048103 37 0.015
cellular carbohydrate metabolic process GO:0044262 22 0.015
divalent inorganic cation transport GO:0072511 30 0.014
reproductive system development GO:0061458 74 0.014
Mouse
actin mediated cell contraction GO:0070252 21 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
detection of external stimulus GO:0009581 66 0.014
nucleoside phosphate biosynthetic process GO:1901293 34 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
negative regulation of organelle organization GO:0010639 56 0.013
regulation of ion transport GO:0043269 39 0.013
Human Rat
courtship behavior GO:0007619 68 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
cellular protein complex assembly GO:0043623 71 0.013
Mouse
nucleoside triphosphate catabolic process GO:0009143 108 0.013
maintenance of apical basal cell polarity GO:0035090 8 0.013
nucleotide catabolic process GO:0009166 109 0.013
regulation of smoothened signaling pathway GO:0008589 28 0.013
ion transport GO:0006811 145 0.013
Human Rat
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.013
body morphogenesis GO:0010171 2 0.013
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.013
positive regulation of chromatin silencing at telomere GO:0031940 2 0.013
hair cell differentiation GO:0035315 47 0.013
multi multicellular organism process GO:0044706 123 0.013
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.013
telencephalon development GO:0021537 2 0.013
mapk cascade GO:0000165 107 0.013
digestive tract morphogenesis GO:0048546 127 0.013
protein ubiquitination GO:0016567 70 0.012
positive regulation of organelle organization GO:0010638 65 0.012
Mouse
wnt signaling pathway GO:0016055 98 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
establishment of nucleus localization GO:0040023 26 0.012
regulation of cell shape GO:0008360 113 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
Mouse
innate immune response GO:0045087 144 0.012
signal release GO:0023061 49 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
single organism catabolic process GO:0044712 228 0.012
oocyte morphogenesis GO:0048601 3 0.012
regulation of necrotic cell death GO:0010939 1 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
Mouse
tendon development GO:0035989 1 0.012
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012

dlg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
nervous system disease DOID:863 0 0.074
brachydactyly DOID:0050581 0 0.015
bone development disease DOID:0080006 0 0.015
bone disease DOID:0080001 0 0.015
dysostosis DOID:1934 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015