Drosophila melanogaster

95 known processes

brn (Dmel_CG4934)

brainiac

(Aliases: EG:EG0007.6,fs(1)107,fs(1)A107,Dmel\CG4934,l(1)6P6,CG4934,brc)

brn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.646
chemotaxis GO:0006935 249 0.561
taxis GO:0042330 304 0.484
neuron projection guidance GO:0097485 241 0.469
axon development GO:0061564 297 0.355
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.321
axon guidance GO:0007411 233 0.280
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.264
positive regulation of gene expression GO:0010628 290 0.249
positive regulation of cellular biosynthetic process GO:0031328 316 0.232
regulation of cell differentiation GO:0045595 302 0.157
intracellular signal transduction GO:0035556 300 0.156
regulation of intracellular signal transduction GO:1902531 236 0.154
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.154
positive regulation of response to stimulus GO:0048584 323 0.143
positive regulation of macromolecule metabolic process GO:0010604 405 0.119
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.115
regionalization GO:0003002 416 0.111
regulation of cell morphogenesis GO:0022604 163 0.105
regulation of phosphate metabolic process GO:0019220 210 0.102
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.100
ovarian follicle cell development GO:0030707 248 0.095
stem cell differentiation GO:0048863 117 0.087
phosphorylation GO:0016310 294 0.086
cellular protein modification process GO:0006464 438 0.086
positive regulation of signal transduction GO:0009967 223 0.086
positive regulation of biosynthetic process GO:0009891 316 0.085
positive regulation of signaling GO:0023056 243 0.085
regulation of multi organism process GO:0043900 131 0.084
appendage morphogenesis GO:0035107 397 0.084
regulation of cell cycle GO:0051726 291 0.083
immune system process GO:0002376 347 0.082
positive regulation of nucleic acid templated transcription GO:1903508 266 0.082
digestive tract morphogenesis GO:0048546 127 0.082
central nervous system development GO:0007417 201 0.078
transcription from rna polymerase ii promoter GO:0006366 368 0.076
negative regulation of signaling GO:0023057 219 0.076
regulation of notch signaling pathway GO:0008593 100 0.073
appendage development GO:0048736 401 0.072
cell migration GO:0016477 238 0.072
wing disc morphogenesis GO:0007472 344 0.072
camera type eye development GO:0043010 4 0.071
notch signaling pathway GO:0007219 120 0.068
embryonic morphogenesis GO:0048598 206 0.067
positive regulation of rna metabolic process GO:0051254 271 0.066
imaginal disc derived appendage morphogenesis GO:0035114 395 0.064
compound eye photoreceptor cell differentiation GO:0001751 140 0.064
cell fate specification GO:0001708 71 0.063
vesicle mediated transport GO:0016192 381 0.062
protein phosphorylation GO:0006468 169 0.061
protein modification process GO:0036211 438 0.059
tube morphogenesis GO:0035239 191 0.059
gland development GO:0048732 191 0.057
epithelial cell development GO:0002064 274 0.057
response to abiotic stimulus GO:0009628 341 0.056
sensory organ morphogenesis GO:0090596 260 0.056
intracellular transport GO:0046907 228 0.055
positive regulation of cell communication GO:0010647 250 0.055
regulation of immune system process GO:0002682 176 0.054
regulation of cell development GO:0060284 215 0.052
tube development GO:0035295 244 0.052
body morphogenesis GO:0010171 2 0.051
positive regulation of transcription dna templated GO:0045893 266 0.049
epithelial cell differentiation GO:0030855 322 0.049
response to other organism GO:0051707 293 0.048
immune effector process GO:0002252 98 0.048
negative regulation of gene expression GO:0010629 387 0.048
reproductive behavior GO:0019098 122 0.048
cuticle pattern formation GO:0035017 27 0.048
regulation of multicellular organismal development GO:2000026 414 0.047
morphogenesis of an epithelium GO:0002009 276 0.047
cellular amine metabolic process GO:0044106 12 0.046
regulation of cell cycle process GO:0010564 181 0.046
single organism behavior GO:0044708 391 0.046
regulation of localization GO:0032879 275 0.045
cytoplasmic transport GO:0016482 130 0.044
digestive tract development GO:0048565 149 0.044
cell fate determination GO:0001709 91 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
neurological system process GO:0050877 358 0.044
negative regulation of phosphorus metabolic process GO:0010563 45 0.044
regulation of cell projection organization GO:0031344 92 0.043
cellular catabolic process GO:0044248 372 0.043
nephron tubule development GO:0072080 3 0.042
regulation of protein metabolic process GO:0051246 256 0.042
regulation of phosphorus metabolic process GO:0051174 210 0.042
cell projection assembly GO:0030031 94 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
negative regulation of biosynthetic process GO:0009890 277 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
dna metabolic process GO:0006259 227 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
meiotic cell cycle process GO:1903046 132 0.039
negative regulation of phosphate metabolic process GO:0045936 45 0.039
post embryonic appendage morphogenesis GO:0035120 385 0.038
regulation of nervous system development GO:0051960 248 0.038
dendrite morphogenesis GO:0048813 199 0.038
asymmetric cell division GO:0008356 37 0.038
cytokinesis GO:0000910 90 0.037
blastoderm segmentation GO:0007350 159 0.037
brain development GO:0007420 120 0.037
protein complex biogenesis GO:0070271 201 0.037
signal transduction by phosphorylation GO:0023014 107 0.037
phagocytosis GO:0006909 215 0.037
embryo development ending in birth or egg hatching GO:0009792 152 0.036
regulation of cellular amine metabolic process GO:0033238 3 0.036
cell proliferation GO:0008283 299 0.036
amine metabolic process GO:0009308 12 0.036
actin cytoskeleton organization GO:0030036 206 0.036
organelle fission GO:0048285 340 0.036
segmentation GO:0035282 207 0.035
cellular amino acid metabolic process GO:0006520 61 0.034
exocrine system development GO:0035272 162 0.034
regulation of mapk cascade GO:0043408 92 0.034
imaginal disc pattern formation GO:0007447 91 0.033
cell division GO:0051301 248 0.033
regulation of molecular function GO:0065009 217 0.033
retina development in camera type eye GO:0060041 4 0.033
multi organism behavior GO:0051705 175 0.033
regulation of cell death GO:0010941 173 0.033
eggshell chorion assembly GO:0007306 66 0.032
regulation of anatomical structure size GO:0090066 163 0.032
dendrite development GO:0016358 204 0.032
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
mapk cascade GO:0000165 107 0.031
renal system development GO:0072001 72 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
mitotic nuclear division GO:0007067 213 0.031
kidney development GO:0001822 3 0.030
negative regulation of phosphorylation GO:0042326 35 0.030
oxoacid metabolic process GO:0043436 103 0.030
protein localization GO:0008104 284 0.029
positive regulation of cell migration GO:0030335 2 0.029
eye development GO:0001654 323 0.028
neuron recognition GO:0008038 101 0.028
negative regulation of cell communication GO:0010648 223 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
regulation of reproductive process GO:2000241 54 0.027
regulation of microtubule cytoskeleton organization GO:0070507 41 0.027
lateral inhibition GO:0046331 206 0.027
ameboidal type cell migration GO:0001667 151 0.027
nucleus localization GO:0051647 34 0.026
endodermal cell fate commitment GO:0001711 3 0.026
sensory perception GO:0007600 196 0.026
formation of organ boundary GO:0010160 30 0.026
developmental programmed cell death GO:0010623 138 0.026
response to organic substance GO:0010033 284 0.026
regulation of cellular localization GO:0060341 136 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.026
regulation of neurogenesis GO:0050767 158 0.026
stem cell maintenance GO:0019827 67 0.025
renal tubule morphogenesis GO:0061333 44 0.025
negative regulation of organelle organization GO:0010639 56 0.025
actin filament based process GO:0030029 220 0.025
negative regulation of notch signaling pathway GO:0045746 41 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
cell adhesion GO:0007155 136 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
negative regulation of rna biosynthetic process GO:1902679 240 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
multi multicellular organism process GO:0044706 123 0.024
regulation of catalytic activity GO:0050790 185 0.024
cellular lipid metabolic process GO:0044255 83 0.024
cellular protein localization GO:0034613 160 0.023
cell motility GO:0048870 251 0.023
dorsal appendage formation GO:0046843 47 0.023
response to biotic stimulus GO:0009607 294 0.023
positive regulation of developmental process GO:0051094 143 0.023
eye morphogenesis GO:0048592 260 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
regulation of catabolic process GO:0009894 170 0.023
wnt signaling pathway GO:0016055 98 0.023
cell cycle arrest GO:0007050 4 0.023
sex determination GO:0007530 18 0.023
regulation of organelle organization GO:0033043 196 0.022
regulation of phosphorylation GO:0042325 147 0.022
peptidyl amino acid modification GO:0018193 105 0.022
negative regulation of signal transduction GO:0009968 206 0.022
regulation of organ morphogenesis GO:2000027 78 0.022
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.022
regulation of neuron differentiation GO:0045664 103 0.022
organic substance transport GO:0071702 257 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
nuclear division GO:0000280 332 0.022
phenol containing compound metabolic process GO:0018958 57 0.022
defense response GO:0006952 300 0.021
spindle organization GO:0007051 253 0.021
regulation of microtubule based process GO:0032886 49 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
eye photoreceptor cell development GO:0042462 81 0.021
cellular ketone metabolic process GO:0042180 24 0.021
ubiquitin dependent protein catabolic process GO:0006511 78 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
small molecule metabolic process GO:0044281 305 0.021
renal tubule development GO:0061326 64 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
positive regulation of cell motility GO:2000147 3 0.020
embryonic axis specification GO:0000578 107 0.020
membrane organization GO:0061024 112 0.020
mitotic spindle organization GO:0007052 220 0.020
regulation of transport GO:0051049 181 0.020
eye photoreceptor cell differentiation GO:0001754 145 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
salivary gland morphogenesis GO:0007435 145 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.020
rna splicing GO:0008380 83 0.019
leg disc development GO:0035218 92 0.019
regulation of protein complex disassembly GO:0043244 29 0.019
regulation of cell division GO:0051302 72 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
mesoderm development GO:0007498 78 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
antimicrobial humoral response GO:0019730 99 0.019
establishment of localization in cell GO:0051649 402 0.019
rna processing GO:0006396 147 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.019
microtubule based movement GO:0007018 51 0.019
wing disc pattern formation GO:0035222 66 0.019
cytoskeleton dependent intracellular transport GO:0030705 44 0.019
cytoskeleton dependent cytokinesis GO:0061640 81 0.019
endodermal cell differentiation GO:0035987 3 0.019
humoral immune response GO:0006959 117 0.018
catabolic process GO:0009056 409 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
regulation of protein transport GO:0051223 57 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
kidney epithelium development GO:0072073 3 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
negative regulation of protein modification process GO:0031400 29 0.018
negative regulation of cell cycle GO:0045786 116 0.018
chorion containing eggshell formation GO:0007304 105 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
negative regulation of developmental process GO:0051093 201 0.017
establishment of organelle localization GO:0051656 122 0.017
salivary gland development GO:0007431 162 0.017
gastrulation GO:0007369 70 0.017
nephron epithelium morphogenesis GO:0072088 3 0.017
negative regulation of cytoskeleton organization GO:0051494 30 0.017
positive regulation of catabolic process GO:0009896 105 0.017
organelle localization GO:0051640 148 0.017
immune response GO:0006955 246 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
embryonic pattern specification GO:0009880 174 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
negative regulation of protein complex disassembly GO:0043242 23 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
single organismal cell cell adhesion GO:0016337 45 0.017
protein palmitoylation GO:0018345 2 0.017
embryonic hindgut morphogenesis GO:0048619 48 0.017
protein complex assembly GO:0006461 200 0.017
nephron epithelium development GO:0072009 3 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
defense response to other organism GO:0098542 225 0.016
regulation of intracellular transport GO:0032386 64 0.016
microtubule based transport GO:0010970 42 0.016
negative regulation of microtubule depolymerization GO:0007026 21 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
secretion GO:0046903 109 0.016
regulation of protein complex assembly GO:0043254 42 0.016
gliogenesis GO:0042063 80 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
regulation of embryonic development GO:0045995 68 0.016
photoreceptor cell development GO:0042461 96 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
endocytosis GO:0006897 310 0.016
hematopoietic or lymphoid organ development GO:0048534 57 0.016
digestive system development GO:0055123 149 0.016
nephron development GO:0072006 3 0.016
regulation of protein localization GO:0032880 76 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
regulation of mitotic cell cycle GO:0007346 190 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
positive regulation of transport GO:0051050 92 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
organic acid metabolic process GO:0006082 103 0.015
hindgut morphogenesis GO:0007442 58 0.015
hemopoiesis GO:0030097 46 0.015
anterior posterior pattern specification GO:0009952 136 0.015
head development GO:0060322 135 0.015
organic substance catabolic process GO:1901575 308 0.015
regulation of immune response GO:0050776 118 0.015
regulation of mitosis GO:0007088 56 0.015
kidney morphogenesis GO:0060993 3 0.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
nucleotide metabolic process GO:0009117 161 0.014
ras protein signal transduction GO:0007265 88 0.014
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.014
programmed cell death GO:0012501 257 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
positive regulation of cell death GO:0010942 69 0.014
regulation of protein depolymerization GO:1901879 27 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
death GO:0016265 284 0.014
stem cell development GO:0048864 79 0.014
protein heterooligomerization GO:0051291 4 0.014
regulation of response to stress GO:0080134 200 0.014
peripheral nervous system development GO:0007422 52 0.014
negative regulation of protein depolymerization GO:1901880 23 0.013
apoptotic process GO:0006915 159 0.013
positive regulation of molecular function GO:0044093 136 0.013
cell cycle phase transition GO:0044770 140 0.013
response to organophosphorus GO:0046683 2 0.013
actin filament organization GO:0007015 126 0.013
mitotic cytokinesis GO:0000281 50 0.013
regulation of pole plasm oskar mrna localization GO:0007317 27 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
wound healing GO:0042060 75 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
dna templated transcription elongation GO:0006354 18 0.013
cell death GO:0008219 279 0.013
cuticle development GO:0042335 86 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
female sex differentiation GO:0046660 20 0.013
asymmetric protein localization GO:0008105 33 0.013
establishment of nucleus localization GO:0040023 26 0.013
locomotory behavior GO:0007626 176 0.013
reproductive system development GO:0061458 74 0.013
molting cycle GO:0042303 56 0.012
immune response activating signal transduction GO:0002757 2 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
gland morphogenesis GO:0022612 145 0.012
protein complex disassembly GO:0043241 36 0.012
nephron tubule morphogenesis GO:0072078 3 0.012
regulation of production of molecular mediator of immune response GO:0002700 44 0.012
oviposition GO:0018991 19 0.012
response to oxygen containing compound GO:1901700 200 0.012
gonad development GO:0008406 50 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
positive regulation of protein transport GO:0051222 37 0.012
response to alcohol GO:0097305 95 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
hindbrain development GO:0030902 2 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
negative regulation of protein phosphorylation GO:0001933 17 0.012
proteolysis GO:0006508 192 0.012
protein localization to organelle GO:0033365 82 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
regulation of defense response GO:0031347 102 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
sex differentiation GO:0007548 81 0.012
protein import into nucleus GO:0006606 51 0.011
protein localization to nucleus GO:0034504 55 0.011
regulation of locomotion GO:0040012 42 0.011
nephron morphogenesis GO:0072028 3 0.011
innate immune response GO:0045087 144 0.011
single organism cell adhesion GO:0098602 47 0.011
meiosis i GO:0007127 59 0.011
asymmetric stem cell division GO:0098722 49 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
positive regulation of immune system process GO:0002684 68 0.011
determination of adult lifespan GO:0008340 137 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
camera type eye morphogenesis GO:0048593 2 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
open tracheal system development GO:0007424 204 0.011
response to radiation GO:0009314 155 0.011
neuroblast proliferation GO:0007405 74 0.011
connective tissue development GO:0061448 3 0.011
cell aging GO:0007569 2 0.011
macromolecular complex assembly GO:0065003 256 0.011
chromosome condensation GO:0030261 41 0.011
nuclear transport GO:0051169 72 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
larval development GO:0002164 104 0.011
multi organism reproductive behavior GO:0044705 121 0.011
regulation of antimicrobial peptide production GO:0002784 44 0.011
chromosome segregation GO:0007059 157 0.011
eggshell formation GO:0030703 105 0.011
dna dependent dna replication GO:0006261 17 0.011
peptidyl lysine modification GO:0018205 57 0.011
axon target recognition GO:0007412 16 0.011
mesenchymal cell development GO:0014031 1 0.010
regulation of transferase activity GO:0051338 58 0.010
regulation of protein secretion GO:0050708 13 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
regulation of protein polymerization GO:0032271 28 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
female germ line stem cell asymmetric division GO:0048132 14 0.010
urogenital system development GO:0001655 72 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
glial cell differentiation GO:0010001 35 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
regulation of protein modification process GO:0031399 112 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
tripartite regional subdivision GO:0007351 103 0.010
positive regulation of immune response GO:0050778 63 0.010
compound eye morphogenesis GO:0001745 249 0.010
response to lipid GO:0033993 38 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
negative regulation of chromosome segregation GO:0051985 14 0.010
microtubule polymerization or depolymerization GO:0031109 39 0.010

brn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
bone development disease DOID:0080006 0 0.012
bone disease DOID:0080001 0 0.012
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012