Drosophila melanogaster

132 known processes

Cdk5 (Dmel_CG8203)

Cyclin-dependent kinase 5

(Aliases: CG8203,cdk5,CDK5,DmCdk5,Dmel\CG8203)

Cdk5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.825
Mouse Rat Worm
regulation of cell cycle GO:0051726 291 0.818
single organism intracellular transport GO:1902582 207 0.598
Mouse
regulation of cell cycle process GO:0010564 181 0.527
organelle localization GO:0051640 148 0.402
protein localization GO:0008104 284 0.334
Mouse Worm
regulation of multicellular organismal development GO:2000026 414 0.288
protein prenylation GO:0018342 3 0.284
negative regulation of cell cycle GO:0045786 116 0.265
Mouse
cell proliferation GO:0008283 299 0.232
neurological system process GO:0050877 358 0.205
Mouse
regulation of mitotic cell cycle GO:0007346 190 0.201
cellular macromolecule localization GO:0070727 220 0.198
Mouse
intracellular transport GO:0046907 228 0.191
Mouse Rat
nuclear division GO:0000280 332 0.149
homeostatic process GO:0042592 199 0.127
ras protein signal transduction GO:0007265 88 0.122
negative regulation of cell cycle phase transition GO:1901988 103 0.117
regulation of cell division GO:0051302 72 0.110
nucleobase containing compound catabolic process GO:0034655 165 0.108
regulation of cellular localization GO:0060341 136 0.106
Mouse
regulation of molecular function GO:0065009 217 0.104
Mouse
cell division GO:0051301 248 0.100
regulation of cell proliferation GO:0042127 163 0.095
regulation of immune system process GO:0002682 176 0.094
intracellular protein transport GO:0006886 104 0.088
Mouse
protein complex assembly GO:0006461 200 0.078
phosphorylation GO:0016310 294 0.076
cellular protein modification process GO:0006464 438 0.072
intracellular signal transduction GO:0035556 300 0.072
negative regulation of multicellular organismal process GO:0051241 142 0.072
Mouse
cellular response to dna damage stimulus GO:0006974 223 0.072
endomembrane system organization GO:0010256 119 0.071
negative regulation of response to stimulus GO:0048585 258 0.068
aromatic compound catabolic process GO:0019439 166 0.064
regulation of cell cycle phase transition GO:1901987 130 0.064
dorsal ventral pattern formation GO:0009953 133 0.063
regulation of phosphate metabolic process GO:0019220 210 0.063
Mouse
regulation of protein stability GO:0031647 43 0.061
single organism membrane organization GO:0044802 93 0.060
Mouse
establishment of protein localization GO:0045184 163 0.060
Mouse
ribonucleoside catabolic process GO:0042454 112 0.059
regionalization GO:0003002 416 0.058
endocytosis GO:0006897 310 0.057
Rat
negative regulation of cell cycle process GO:0010948 109 0.056
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.055
Human
protein modification process GO:0036211 438 0.054
vesicle organization GO:0016050 44 0.053
axonogenesis GO:0007409 290 0.052
rna processing GO:0006396 147 0.052
negative regulation of mitotic cell cycle GO:0045930 109 0.052
cell adhesion GO:0007155 136 0.050
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.050
small gtpase mediated signal transduction GO:0007264 88 0.047
asymmetric cell division GO:0008356 37 0.044
organic cyclic compound catabolic process GO:1901361 168 0.044
localization of cell GO:0051674 257 0.044
Mouse
macromolecular complex assembly GO:0065003 256 0.044
protein transport GO:0015031 155 0.043
Mouse
mitotic nuclear division GO:0007067 213 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
Human
vesicle mediated transport GO:0016192 381 0.040
Mouse Rat Worm
telencephalon development GO:0021537 2 0.040
Mouse
dendrite development GO:0016358 204 0.039
Mouse
regulation of cell development GO:0060284 215 0.038
Mouse
divalent metal ion transport GO:0070838 26 0.038
positive regulation of rna biosynthetic process GO:1902680 266 0.037
regulation of protein localization GO:0032880 76 0.037
Mouse Worm
death GO:0016265 284 0.037
regulation of anatomical structure size GO:0090066 163 0.036
Mouse
ribonucleoside metabolic process GO:0009119 127 0.036
neural precursor cell proliferation GO:0061351 75 0.036
protein complex biogenesis GO:0070271 201 0.035
catabolic process GO:0009056 409 0.035
Mouse
cellular protein complex assembly GO:0043623 71 0.035
immune system process GO:0002376 347 0.034
programmed cell death GO:0012501 257 0.034
single organism cellular localization GO:1902580 180 0.034
Mouse
small molecule metabolic process GO:0044281 305 0.034
heterocycle catabolic process GO:0046700 166 0.033
ribonucleoside triphosphate catabolic process GO:0009203 108 0.033
nucleoside catabolic process GO:0009164 112 0.033
rna localization GO:0006403 115 0.033
regulation of catalytic activity GO:0050790 185 0.032
Mouse
maintenance of location GO:0051235 73 0.032
cellular cation homeostasis GO:0030003 38 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
Human
regulation of nucleotide metabolic process GO:0006140 62 0.031
negative regulation of signal transduction GO:0009968 206 0.031
retina development in camera type eye GO:0060041 4 0.030
Zebrafish
protein phosphorylation GO:0006468 169 0.030
negative regulation of epithelial cell proliferation GO:0050680 4 0.030
regulation of intracellular signal transduction GO:1902531 236 0.029
Mouse
chemotaxis GO:0006935 249 0.029
protein palmitoylation GO:0018345 2 0.029
transcription from rna polymerase ii promoter GO:0006366 368 0.028
positive regulation of transport GO:0051050 92 0.028
Mouse
protein targeting GO:0006605 64 0.027
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.027
positive regulation of signal transduction GO:0009967 223 0.027
regulation of cellular response to stress GO:0080135 89 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.026
regulation of double strand break repair GO:2000779 3 0.026
organic substance transport GO:0071702 257 0.026
Mouse
regulation of phosphorylation GO:0042325 147 0.025
Mouse
positive regulation of cell cycle GO:0045787 43 0.025
regulation of vesicle mediated transport GO:0060627 59 0.025
Mouse
cortical actin cytoskeleton organization GO:0030866 24 0.025
Rat
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
Mouse
negative regulation of cell proliferation GO:0008285 69 0.025
cell motility GO:0048870 251 0.025
Mouse
response to radiation GO:0009314 155 0.025
Mouse
positive regulation of catalytic activity GO:0043085 118 0.024
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.023
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.023
mitotic cell cycle checkpoint GO:0007093 88 0.023
proteolysis GO:0006508 192 0.023
Human
gtp catabolic process GO:0006184 72 0.023
glycosyl compound metabolic process GO:1901657 127 0.022
organic substance catabolic process GO:1901575 308 0.022
Mouse
transmission of nerve impulse GO:0019226 12 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
ion transport GO:0006811 145 0.022
Mouse
cellular nitrogen compound catabolic process GO:0044270 165 0.022
negative regulation of rna metabolic process GO:0051253 251 0.021
Human
organonitrogen compound metabolic process GO:1901564 318 0.021
cytoplasmic transport GO:0016482 130 0.021
Mouse Rat
negative regulation of cellular component organization GO:0051129 108 0.021
Mouse
neuronal action potential GO:0019228 10 0.020
cellular component disassembly GO:0022411 46 0.020
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
Human Mouse
regulation of immune response GO:0050776 118 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
gliogenesis GO:0042063 80 0.019
Human Mouse
response to oxygen containing compound GO:1901700 200 0.019
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.019
Human Mouse
response to external biotic stimulus GO:0043207 293 0.019
mitotic g2 m transition checkpoint GO:0044818 70 0.019
protein localization to plasma membrane GO:0072659 13 0.019
apoptotic process GO:0006915 159 0.018
positive regulation of cell communication GO:0010647 250 0.018
jak stat cascade GO:0007259 49 0.018
positive regulation of nucleoside metabolic process GO:0045979 47 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
positive regulation of molecular function GO:0044093 136 0.017
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
Mouse
regulation of microtubule based process GO:0032886 49 0.017
mitotic dna integrity checkpoint GO:0044774 75 0.017
regulation of hydrolase activity GO:0051336 97 0.017
nucleoside metabolic process GO:0009116 127 0.016
regulation of localization GO:0032879 275 0.016
Mouse Worm
forebrain development GO:0030900 2 0.016
Mouse
centrosome organization GO:0051297 163 0.016
response to endogenous stimulus GO:0009719 119 0.016
Mouse
protein geranylgeranylation GO:0018344 3 0.016
camera type eye development GO:0043010 4 0.016
Zebrafish
positive regulation of immune response GO:0050778 63 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
Rat
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
neuron projection guidance GO:0097485 241 0.015
regulation of transport GO:0051049 181 0.015
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
protein polymerization GO:0051258 42 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
mitotic cell cycle embryonic GO:0045448 38 0.015
regulation of organelle organization GO:0033043 196 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
Human
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
response to other organism GO:0051707 293 0.014
regulation of response to stress GO:0080134 200 0.014
establishment of protein localization to organelle GO:0072594 62 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
cell aging GO:0007569 2 0.014
molting cycle GO:0042303 56 0.014
chaeta development GO:0022416 97 0.014
cellular homeostasis GO:0019725 80 0.014
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
Mouse
positive regulation of phosphorylation GO:0042327 87 0.014
Mouse
single organism biosynthetic process GO:0044711 206 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
ribonucleotide metabolic process GO:0009259 145 0.013
single organism nuclear import GO:1902593 51 0.013
regulation of neuron differentiation GO:0045664 103 0.013
Mouse
eye development GO:0001654 323 0.013
Zebrafish
positive regulation of signaling GO:0023056 243 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
Mouse
ion homeostasis GO:0050801 55 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
positive regulation of cell development GO:0010720 61 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
negative regulation of developmental process GO:0051093 201 0.012
Mouse
axon ensheathment GO:0008366 10 0.012
positive regulation of cell motility GO:2000147 3 0.012
peptidyl amino acid modification GO:0018193 105 0.012
Human Mouse Rat
phagocytosis GO:0006909 215 0.012
regulation of transferase activity GO:0051338 58 0.012
Mouse
regulation of nucleoside metabolic process GO:0009118 50 0.012
nuclear transport GO:0051169 72 0.012
Mouse Rat
purine containing compound metabolic process GO:0072521 155 0.012
nucleotide metabolic process GO:0009117 161 0.011
photoreceptor cell development GO:0042461 96 0.011
detection of visible light GO:0009584 38 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
axon guidance GO:0007411 233 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
regulation of proteolysis GO:0030162 87 0.011
Human
purine containing compound catabolic process GO:0072523 112 0.011
phosphorylation of rna polymerase ii c terminal domain GO:0070816 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
Mouse
positive regulation of gene expression GO:0010628 290 0.011
negative regulation of nervous system development GO:0051961 92 0.011
Mouse
developmental maturation GO:0021700 172 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
cellular amine metabolic process GO:0044106 12 0.010
negative regulation of intracellular signal transduction GO:1902532 57 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
purine nucleoside catabolic process GO:0006152 112 0.010

Cdk5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
disease of cellular proliferation DOID:14566 0 0.016