Drosophila melanogaster

22 known processes

GstE6 (Dmel_CG17530)

Glutathione S transferase E6

(Aliases: Dmel\CG17530,DmGSTE6,CG17530,GSTE6,CT38747)

GstE6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glutathione metabolic process GO:0006749 37 1.000
cellular modified amino acid metabolic process GO:0006575 45 1.000
peptide metabolic process GO:0006518 80 0.999
sulfur compound metabolic process GO:0006790 59 0.998
cellular amide metabolic process GO:0043603 80 0.993
response to heat GO:0009408 63 0.971
Fly
small molecule metabolic process GO:0044281 305 0.954
cellular amino acid metabolic process GO:0006520 61 0.946
oxoacid metabolic process GO:0043436 103 0.937
organic acid metabolic process GO:0006082 103 0.910
response to temperature stimulus GO:0009266 106 0.877
Fly
response to abiotic stimulus GO:0009628 341 0.800
Fly
organonitrogen compound metabolic process GO:1901564 318 0.798
carboxylic acid metabolic process GO:0019752 92 0.693
xenobiotic catabolic process GO:0042178 1 0.484
vitamin metabolic process GO:0006766 2 0.263
small molecule biosynthetic process GO:0044283 37 0.217
cellular aldehyde metabolic process GO:0006081 10 0.170
eye pigment metabolic process GO:0042441 33 0.115
dna metabolic process GO:0006259 227 0.115
sesquiterpenoid metabolic process GO:0006714 3 0.101
death GO:0016265 284 0.100
cellular catabolic process GO:0044248 372 0.099
catabolic process GO:0009056 409 0.087
organic substance catabolic process GO:1901575 308 0.081
response to oxygen containing compound GO:1901700 200 0.076
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.073
single organism biosynthetic process GO:0044711 206 0.069
small molecule catabolic process GO:0044282 21 0.068
mushroom body development GO:0016319 70 0.065
single organism carbohydrate metabolic process GO:0044723 72 0.064
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.064
cell death GO:0008219 279 0.061
neurological system process GO:0050877 358 0.060
lipid catabolic process GO:0016042 21 0.060
protein localization GO:0008104 284 0.057
regulation of mrna splicing via spliceosome GO:0048024 64 0.057
single organism catabolic process GO:0044712 228 0.055
aggressive behavior GO:0002118 63 0.054
sensory perception GO:0007600 196 0.054
response to extracellular stimulus GO:0009991 116 0.054
monocarboxylic acid metabolic process GO:0032787 29 0.052
protein modification process GO:0036211 438 0.052
organic hydroxy compound metabolic process GO:1901615 83 0.051
cellular ketone metabolic process GO:0042180 24 0.051
polyol biosynthetic process GO:0046173 3 0.049
response to oxidative stress GO:0006979 86 0.047
organelle fission GO:0048285 340 0.046
cellular response to chemical stimulus GO:0070887 199 0.046
response to organic substance GO:0010033 284 0.044
regulation of cell death GO:0010941 173 0.043
regulation of cellular localization GO:0060341 136 0.042
negative regulation of rna metabolic process GO:0051253 251 0.041
cellular response to oxidative stress GO:0034599 28 0.041
apoptotic process GO:0006915 159 0.039
maintenance of location GO:0051235 73 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.038
cellular amine metabolic process GO:0044106 12 0.037
response to organophosphorus GO:0046683 2 0.037
cellular lipid catabolic process GO:0044242 16 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
secondary metabolic process GO:0019748 75 0.037
rna splicing GO:0008380 83 0.037
regulation of cell proliferation GO:0042127 163 0.036
cellular protein modification process GO:0006464 438 0.035
cellular lipid metabolic process GO:0044255 83 0.035
regulation of multicellular organismal development GO:2000026 414 0.034
regulation of rna splicing GO:0043484 69 0.034
telencephalon development GO:0021537 2 0.034
phosphorylation GO:0016310 294 0.034
male gamete generation GO:0048232 201 0.033
regulation of cellular ketone metabolic process GO:0010565 3 0.033
primary alcohol metabolic process GO:0034308 2 0.033
regionalization GO:0003002 416 0.032
glycosyl compound metabolic process GO:1901657 127 0.031
steroid catabolic process GO:0006706 1 0.031
developmental pigmentation GO:0048066 68 0.030
nuclear division GO:0000280 332 0.030
homeostatic process GO:0042592 199 0.030
head development GO:0060322 135 0.030
appendage morphogenesis GO:0035107 397 0.030
brain development GO:0007420 120 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
appendage development GO:0048736 401 0.029
epidermis development GO:0008544 65 0.028
negative regulation of gene expression GO:0010629 387 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
cellular response to organic substance GO:0071310 132 0.027
amine metabolic process GO:0009308 12 0.027
cell proliferation GO:0008283 299 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
pigmentation GO:0043473 75 0.027
response to starvation GO:0042594 97 0.027
protein import GO:0017038 55 0.027
programmed cell death GO:0012501 257 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
response to biotic stimulus GO:0009607 294 0.026
forebrain development GO:0030900 2 0.025
intracellular transport GO:0046907 228 0.025
quinone metabolic process GO:1901661 1 0.025
regulation of programmed cell death GO:0043067 152 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
response to acid chemical GO:0001101 25 0.024
inorganic ion transmembrane transport GO:0098660 73 0.024
establishment of localization in cell GO:0051649 402 0.024
androgen metabolic process GO:0008209 1 0.024
regulation of apoptotic process GO:0042981 130 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
retinal metabolic process GO:0042574 2 0.024
sex differentiation GO:0007548 81 0.023
rna splicing via transesterification reactions GO:0000375 73 0.023
response to lipopolysaccharide GO:0032496 4 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
kidney development GO:0001822 3 0.023
spermatogenesis GO:0007283 200 0.023
mrna metabolic process GO:0016071 124 0.023
taxis GO:0042330 304 0.023
establishment of protein localization GO:0045184 163 0.023
protein complex biogenesis GO:0070271 201 0.023
rna processing GO:0006396 147 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
oxidation reduction process GO:0055114 123 0.022
organonitrogen compound catabolic process GO:1901565 128 0.022
response to inorganic substance GO:0010035 44 0.022
lipid metabolic process GO:0006629 121 0.022
response to ketone GO:1901654 34 0.022
organophosphate metabolic process GO:0019637 195 0.021
regulation of response to stress GO:0080134 200 0.021
growth GO:0040007 359 0.021
single organism intracellular transport GO:1902582 207 0.021
regulation of localization GO:0032879 275 0.020
immune system process GO:0002376 347 0.020
meiotic nuclear division GO:0007126 151 0.020
mrna splicing via spliceosome GO:0000398 73 0.020
response to radiation GO:0009314 155 0.020
protein targeting to nucleus GO:0044744 51 0.020
carbohydrate metabolic process GO:0005975 82 0.020
response to nutrient levels GO:0031667 114 0.020
regulation of cell growth GO:0001558 43 0.020
cellular macromolecule localization GO:0070727 220 0.019
positive regulation of cell communication GO:0010647 250 0.019
circulatory system development GO:0072359 82 0.019
organic hydroxy compound catabolic process GO:1901616 4 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
cytosolic calcium ion transport GO:0060401 2 0.019
protein localization to nucleus GO:0034504 55 0.019
epidermal cell differentiation GO:0009913 51 0.019
central nervous system development GO:0007417 201 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
spermatid development GO:0007286 98 0.018
chaeta development GO:0022416 97 0.018
negative regulation of molecular function GO:0044092 51 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
intracellular signal transduction GO:0035556 300 0.018
regulation of growth GO:0040008 233 0.018
reproductive system development GO:0061458 74 0.017
ion transport GO:0006811 145 0.017
stress activated protein kinase signaling cascade GO:0031098 55 0.017
cell aging GO:0007569 2 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
chemosensory behavior GO:0007635 106 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
regulation of phosphorylation GO:0042325 147 0.017
cellular response to xenobiotic stimulus GO:0071466 5 0.017
response to decreased oxygen levels GO:0036293 58 0.017
response to bacterium GO:0009617 198 0.017
hormone metabolic process GO:0042445 33 0.016
skin development GO:0043588 65 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
cellular biogenic amine catabolic process GO:0042402 1 0.016
cell growth GO:0016049 108 0.016
single organism behavior GO:0044708 391 0.016
positive regulation of signal transduction GO:0009967 223 0.016
negative regulation of cell death GO:0060548 81 0.016
mrna processing GO:0006397 104 0.016
determination of adult lifespan GO:0008340 137 0.016
multicellular organismal aging GO:0010259 140 0.016
regulation of molecular function GO:0065009 217 0.016
reproductive structure development GO:0048608 74 0.015
protein kinase b signaling GO:0043491 1 0.015
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.015
sterol metabolic process GO:0016125 12 0.015
imaginal disc derived appendage development GO:0048737 399 0.015
cellular response to nutrient levels GO:0031669 62 0.015
regulation of transport GO:0051049 181 0.015
response to water deprivation GO:0009414 4 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
alcohol metabolic process GO:0006066 25 0.015
response to other organism GO:0051707 293 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
regulation of immune system process GO:0002682 176 0.015
regulation of sequestering of calcium ion GO:0051282 3 0.015
negative regulation of biosynthetic process GO:0009890 277 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
cell redox homeostasis GO:0045454 5 0.014
proteolysis GO:0006508 192 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
response to alcohol GO:0097305 95 0.014
inorganic cation transmembrane transport GO:0098662 61 0.014
calcium ion transport into cytosol GO:0060402 2 0.014
response to light stimulus GO:0009416 124 0.014
vitamin biosynthetic process GO:0009110 1 0.013
intracellular protein transport GO:0006886 104 0.013
single organism nuclear import GO:1902593 51 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
cellular response to decreased oxygen levels GO:0036294 30 0.013
regulation of anatomical structure size GO:0090066 163 0.013
developmental growth GO:0048589 280 0.013
amine catabolic process GO:0009310 1 0.013
regulation of intracellular transport GO:0032386 64 0.013
regulation of mrna processing GO:0050684 71 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
negative regulation of cell communication GO:0010648 223 0.013
regulation of steroid metabolic process GO:0019218 2 0.013
pigment metabolic process GO:0042440 84 0.013
positive regulation of programmed cell death GO:0043068 62 0.012
ion homeostasis GO:0050801 55 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
localization of cell GO:0051674 257 0.012
response to external biotic stimulus GO:0043207 293 0.012
nuclear import GO:0051170 51 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
tube development GO:0035295 244 0.012
protein import into nucleus GO:0006606 51 0.012
organic substance transport GO:0071702 257 0.012
defense response to bacterium GO:0042742 178 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
pigment biosynthetic process GO:0046148 36 0.012
response to ethanol GO:0045471 59 0.012
positive regulation of signaling GO:0023056 243 0.012
peptidyl amino acid modification GO:0018193 105 0.012
negative regulation of growth GO:0045926 84 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
aromatic compound catabolic process GO:0019439 166 0.011
meiotic cell cycle process GO:1903046 132 0.011
intracellular mrna localization GO:0008298 66 0.011
positive regulation of cell death GO:0010942 69 0.011
protein complex assembly GO:0006461 200 0.011
embryonic pattern specification GO:0009880 174 0.011
multi organism behavior GO:0051705 175 0.011
isoprenoid metabolic process GO:0006720 8 0.011
gonad development GO:0008406 50 0.011
single organism cellular localization GO:1902580 180 0.011
release of sequestered calcium ion into cytosol GO:0051209 1 0.011
alcohol catabolic process GO:0046164 4 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
immune response GO:0006955 246 0.011
response to hypoxia GO:0001666 53 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
intracellular receptor signaling pathway GO:0030522 19 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
cell motility GO:0048870 251 0.011
organic acid biosynthetic process GO:0016053 15 0.011
chromosome segregation GO:0007059 157 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of cell cycle GO:0051726 291 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
estrogen metabolic process GO:0008210 1 0.011
negative regulation of sequestering of calcium ion GO:0051283 2 0.011
calcium ion transmembrane transport GO:0070588 17 0.010
cellular response to extracellular stimulus GO:0031668 64 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
regulation of immune response GO:0050776 118 0.010
carbohydrate biosynthetic process GO:0016051 17 0.010
response to drug GO:0042493 17 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
carboxylic acid biosynthetic process GO:0046394 15 0.010
protein phosphorylation GO:0006468 169 0.010
response to lipid GO:0033993 38 0.010
response to organic cyclic compound GO:0014070 89 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
development of primary sexual characteristics GO:0045137 50 0.010

GstE6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.075
disease of metabolism DOID:0014667 0 0.040
inherited metabolic disorder DOID:655 0 0.040
nervous system disease DOID:863 0 0.025
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cardiovascular system disease DOID:1287 0 0.011
lipid metabolism disorder DOID:3146 0 0.011
organ system cancer DOID:0050686 0 0.011
congenital bile acid synthesis defect DOID:0050674 0 0.010
steroid inherited metabolic disorder DOID:1701 0 0.010