Drosophila melanogaster

42 known processes

Megalin (Dmel_CG42611)

CG42611 gene product from transcript CG42611-RA

(Aliases: Dmel\CG42611,CG42611,CG34352,CG12654,Dmel_CG12654,CG12139,Dmel_CG34352,LDLR,CG15316,CT7830,Dmel_CG34339,SOSIE,Dmel_CG12139,anon-WO0140519.108,CG34339)

Megalin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cuticle development GO:0042335 86 0.468
chitin based cuticle development GO:0040003 49 0.356
respiratory system development GO:0060541 213 0.318
taxis GO:0042330 304 0.276
open tracheal system development GO:0007424 204 0.226
cellular protein modification process GO:0006464 438 0.160
wing disc morphogenesis GO:0007472 344 0.159
chemotaxis GO:0006935 249 0.139
positive regulation of macromolecule metabolic process GO:0010604 405 0.138
transcription from rna polymerase ii promoter GO:0006366 368 0.128
negative regulation of signaling GO:0023057 219 0.122
epithelium migration GO:0090132 148 0.120
post embryonic appendage morphogenesis GO:0035120 385 0.113
regulation of multicellular organismal development GO:2000026 414 0.111
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.109
negative regulation of response to stimulus GO:0048585 258 0.107
regulation of protein metabolic process GO:0051246 256 0.099
negative regulation of cellular metabolic process GO:0031324 382 0.094
imaginal disc derived wing morphogenesis GO:0007476 337 0.086
endomembrane system organization GO:0010256 119 0.086
biological adhesion GO:0022610 138 0.084
negative regulation of cell communication GO:0010648 223 0.080
tissue migration GO:0090130 155 0.078
appendage development GO:0048736 401 0.077
appendage morphogenesis GO:0035107 397 0.076
protein modification process GO:0036211 438 0.076
negative regulation of signal transduction GO:0009968 206 0.075
branching involved in open tracheal system development GO:0060446 45 0.075
adult chitin containing cuticle pigmentation GO:0048085 16 0.074
mapk cascade GO:0000165 107 0.073
imaginal disc derived appendage development GO:0048737 399 0.070
positive regulation of cell migration GO:0030335 2 0.069
regulation of molecular function GO:0065009 217 0.069
regulation of hydrolase activity GO:0051336 97 0.068
positive regulation of molecular function GO:0044093 136 0.068
regulation of cell differentiation GO:0045595 302 0.065
regulation of developmental pigmentation GO:0048070 24 0.065
negative regulation of growth GO:0045926 84 0.065
regulation of cell cycle GO:0051726 291 0.063
organonitrogen compound metabolic process GO:1901564 318 0.063
regulation of response to stress GO:0080134 200 0.061
imaginal disc derived appendage morphogenesis GO:0035114 395 0.060
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.060
regulation of cellular amine metabolic process GO:0033238 3 0.058
carbohydrate derivative metabolic process GO:1901135 217 0.057
histoblast morphogenesis GO:0007488 9 0.057
regulation of multi organism process GO:0043900 131 0.056
regulation of cellular protein metabolic process GO:0032268 243 0.056
enzyme linked receptor protein signaling pathway GO:0007167 179 0.055
o glycan processing GO:0016266 3 0.054
regulation of response to external stimulus GO:0032101 115 0.053
regulation of cuticle pigmentation GO:0048079 16 0.053
response to organic substance GO:0010033 284 0.053
cell adhesion GO:0007155 136 0.052
immune response regulating signaling pathway GO:0002764 2 0.052
negative regulation of biosynthetic process GO:0009890 277 0.052
localization of cell GO:0051674 257 0.050
regulation of catalytic activity GO:0050790 185 0.050
small molecule metabolic process GO:0044281 305 0.049
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.049
positive regulation of cell motility GO:2000147 3 0.049
neuron projection guidance GO:0097485 241 0.048
muscle organ development GO:0007517 127 0.048
catabolic process GO:0009056 409 0.047
regulation of localization GO:0032879 275 0.047
organic substance transport GO:0071702 257 0.046
axonogenesis GO:0007409 290 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.045
regulation of phosphate metabolic process GO:0019220 210 0.044
oxoacid metabolic process GO:0043436 103 0.044
cuticle pigmentation GO:0048067 22 0.042
amine metabolic process GO:0009308 12 0.042
chromatin modification GO:0016568 147 0.042
positive regulation of multi organism process GO:0043902 40 0.042
positive regulation of protein metabolic process GO:0051247 128 0.042
cell migration GO:0016477 238 0.041
cell motility GO:0048870 251 0.041
positive regulation of catalytic activity GO:0043085 118 0.040
tube development GO:0035295 244 0.040
negative regulation of gene expression GO:0010629 387 0.040
positive regulation of peptidase activity GO:0010952 29 0.039
response to abiotic stimulus GO:0009628 341 0.039
regulation of proteolysis GO:0030162 87 0.039
regulation of cellular component movement GO:0051270 42 0.039
embryonic development via the syncytial blastoderm GO:0001700 148 0.038
macromolecule catabolic process GO:0009057 161 0.038
proteolysis GO:0006508 192 0.037
regulation of cellular response to stress GO:0080135 89 0.037
regulation of rna splicing GO:0043484 69 0.037
phagocytosis GO:0006909 215 0.037
regulation of cellular ketone metabolic process GO:0010565 3 0.037
intracellular signal transduction GO:0035556 300 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.036
epithelial cell migration GO:0010631 148 0.035
negative regulation of catalytic activity GO:0043086 42 0.035
single organismal cell cell adhesion GO:0016337 45 0.034
positive regulation of phosphate metabolic process GO:0045937 139 0.034
dendrite morphogenesis GO:0048813 199 0.034
regulation of response to biotic stimulus GO:0002831 63 0.034
regulation of endopeptidase activity GO:0052548 36 0.034
regulation of phosphorus metabolic process GO:0051174 210 0.034
ameboidal type cell migration GO:0001667 151 0.033
chitin based cuticle sclerotization GO:0007593 19 0.033
organic substance catabolic process GO:1901575 308 0.033
cell division GO:0051301 248 0.033
embryonic morphogenesis GO:0048598 206 0.032
instar larval development GO:0002168 55 0.032
inter male aggressive behavior GO:0002121 60 0.032
cellular macromolecule localization GO:0070727 220 0.031
cellular ketone metabolic process GO:0042180 24 0.031
regulation of sterol transport GO:0032371 1 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
actin cytoskeleton organization GO:0030036 206 0.031
g protein coupled receptor signaling pathway GO:0007186 136 0.031
positive regulation of hydrolase activity GO:0051345 78 0.031
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.030
neurological system process GO:0050877 358 0.030
regulation of peptidase activity GO:0052547 39 0.030
ribonucleoside catabolic process GO:0042454 112 0.029
axis specification GO:0009798 167 0.029
small gtpase mediated signal transduction GO:0007264 88 0.029
response to light stimulus GO:0009416 124 0.029
axon development GO:0061564 297 0.028
intracellular transport GO:0046907 228 0.028
growth GO:0040007 359 0.028
single organism biosynthetic process GO:0044711 206 0.028
negative regulation of erbb signaling pathway GO:1901185 29 0.028
regionalization GO:0003002 416 0.028
dorsal closure GO:0007391 79 0.028
head development GO:0060322 135 0.027
glycoprotein biosynthetic process GO:0009101 41 0.027
aggressive behavior GO:0002118 63 0.027
regulation of cellular component biogenesis GO:0044087 201 0.027
single organism cell adhesion GO:0098602 47 0.027
morphogenesis of an epithelium GO:0002009 276 0.027
regulation of cell motility GO:2000145 23 0.027
embryo development ending in birth or egg hatching GO:0009792 152 0.026
connective tissue development GO:0061448 3 0.026
dorsal ventral axis specification GO:0009950 66 0.026
endocytosis GO:0006897 310 0.026
cell cell junction organization GO:0045216 55 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
response to toxic substance GO:0009636 22 0.025
cell junction organization GO:0034330 57 0.025
vesicle mediated transport GO:0016192 381 0.025
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.025
negative regulation of intracellular signal transduction GO:1902532 57 0.025
cellular macromolecule catabolic process GO:0044265 136 0.025
regulation of mapk cascade GO:0043408 92 0.025
regulation of cell migration GO:0030334 22 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
protein catabolic process GO:0030163 101 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
positive regulation of signal transduction GO:0009967 223 0.024
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.024
glycoprotein metabolic process GO:0009100 41 0.024
response to wounding GO:0009611 94 0.024
extracellular matrix constituent secretion GO:0070278 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
wound healing GO:0042060 75 0.024
dendrite development GO:0016358 204 0.024
tube morphogenesis GO:0035239 191 0.024
epidermal growth factor receptor signaling pathway GO:0007173 58 0.023
single organism intracellular transport GO:1902582 207 0.023
response to alcohol GO:0097305 95 0.023
developmental growth GO:0048589 280 0.023
regulation of tube architecture open tracheal system GO:0035152 68 0.023
regulation of anatomical structure morphogenesis GO:0022603 242 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
cuticle pattern formation GO:0035017 27 0.023
regulation of phosphorylation GO:0042325 147 0.023
compound eye development GO:0048749 307 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
single organism cellular localization GO:1902580 180 0.022
morphogenesis of a branching structure GO:0001763 45 0.022
chromosome organization GO:0051276 360 0.021
establishment of protein localization GO:0045184 163 0.021
positive regulation of proteolysis GO:0045862 52 0.021
actin filament organization GO:0007015 126 0.021
rna processing GO:0006396 147 0.021
death GO:0016265 284 0.021
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.021
spindle organization GO:0007051 253 0.021
protein phosphorylation GO:0006468 169 0.021
positive regulation of response to external stimulus GO:0032103 44 0.021
detection of visible light GO:0009584 38 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
regulation of intracellular signal transduction GO:1902531 236 0.020
chromosome segregation GO:0007059 157 0.020
regulation of protein localization GO:0032880 76 0.020
memory GO:0007613 94 0.020
digestive system development GO:0055123 149 0.020
immune response activating signal transduction GO:0002757 2 0.020
modification dependent macromolecule catabolic process GO:0043632 79 0.020
molting cycle chitin based cuticle GO:0007591 56 0.019
gene silencing GO:0016458 138 0.019
response to biotic stimulus GO:0009607 294 0.019
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.019
regulation of neurogenesis GO:0050767 158 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
learning or memory GO:0007611 141 0.019
regulation of locomotion GO:0040012 42 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
negative regulation of endopeptidase activity GO:0010951 11 0.019
compound eye photoreceptor development GO:0042051 78 0.019
chromatin organization GO:0006325 207 0.019
intracellular protein transport GO:0006886 104 0.019
cellular amine metabolic process GO:0044106 12 0.019
deactivation of rhodopsin mediated signaling GO:0016059 17 0.019
actin filament bundle assembly GO:0051017 26 0.019
response to ethanol GO:0045471 59 0.019
sensory perception of smell GO:0007608 80 0.019
regulation of anatomical structure size GO:0090066 163 0.019
reproductive system development GO:0061458 74 0.019
protein transport GO:0015031 155 0.019
response to lipopolysaccharide GO:0032496 4 0.019
leg disc development GO:0035218 92 0.018
regulation of cytoskeleton organization GO:0051493 89 0.018
telencephalon development GO:0021537 2 0.018
cytoplasmic transport GO:0016482 130 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
mitotic spindle organization GO:0007052 220 0.018
positive regulation of gtp catabolic process GO:0033126 43 0.018
detection of stimulus involved in sensory perception GO:0050906 92 0.018
negative regulation of molecular function GO:0044092 51 0.018
molting cycle GO:0042303 56 0.018
rna splicing GO:0008380 83 0.018
regulation of protein modification process GO:0031399 112 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
central nervous system development GO:0007417 201 0.018
regulation of cell adhesion GO:0030155 27 0.017
cell cell adhesion GO:0098609 26 0.017
morphogenesis of embryonic epithelium GO:0016331 94 0.017
cellular response to carbohydrate stimulus GO:0071322 4 0.017
apoptotic process GO:0006915 159 0.017
regulation of transferase activity GO:0051338 58 0.017
regulation of cell proliferation GO:0042127 163 0.017
single organism behavior GO:0044708 391 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
regulation of tube length open tracheal system GO:0035159 24 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
mitotic nuclear division GO:0007067 213 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
gtp metabolic process GO:0046039 72 0.017
adult behavior GO:0030534 137 0.017
nucleoside catabolic process GO:0009164 112 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
golgi vesicle transport GO:0048193 27 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
sensory perception GO:0007600 196 0.016
tissue morphogenesis GO:0048729 297 0.016
epithelial cell differentiation GO:0030855 322 0.016
regulation of nucleoside metabolic process GO:0009118 50 0.016
spermatid differentiation GO:0048515 114 0.016
regulation of intracellular transport GO:0032386 64 0.016
cell fate determination GO:0001709 91 0.016
smoothened signaling pathway GO:0007224 49 0.016
regulation of cell shape GO:0008360 113 0.016
cell cell junction assembly GO:0007043 38 0.016
secretion GO:0046903 109 0.016
response to endogenous stimulus GO:0009719 119 0.016
peptidyl amino acid modification GO:0018193 105 0.016
regulation of smoothened signaling pathway GO:0008589 28 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
negative regulation of phosphorus metabolic process GO:0010563 45 0.015
regulation of protein kinase activity GO:0045859 51 0.015
membrane depolarization GO:0051899 4 0.015
positive regulation of cell proliferation GO:0008284 47 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
regulation of behavior GO:0050795 75 0.015
negative regulation of developmental growth GO:0048640 64 0.015
adult locomotory behavior GO:0008344 76 0.015
spermatid development GO:0007286 98 0.015
regulation of reproductive process GO:2000241 54 0.015
ion transport GO:0006811 145 0.015
negative regulation of organ growth GO:0046621 15 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
regulation of response to wounding GO:1903034 19 0.015
cellular response to organic substance GO:0071310 132 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
cellular protein catabolic process GO:0044257 83 0.015
organic acid metabolic process GO:0006082 103 0.015
striated muscle tissue development GO:0014706 27 0.015
posttranscriptional gene silencing by rna GO:0035194 45 0.015
branch fusion open tracheal system GO:0035147 17 0.015
regulation of mrna processing GO:0050684 71 0.015
sensory organ morphogenesis GO:0090596 260 0.015
regulation of growth GO:0040008 233 0.014
male gamete generation GO:0048232 201 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
golgi organization GO:0007030 66 0.014
metal ion transport GO:0030001 74 0.014
protein maturation GO:0051604 71 0.014
phosphorylation GO:0016310 294 0.014
regulation of cytoplasmic transport GO:1903649 47 0.014
positive regulation of gene expression GO:0010628 290 0.014
cellular response to light stimulus GO:0071482 37 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of organelle organization GO:0033043 196 0.014
regulation of transport GO:0051049 181 0.014
larval development GO:0002164 104 0.014
regulation of apoptotic process GO:0042981 130 0.014
eye pigmentation GO:0048069 43 0.014
transmembrane transport GO:0055085 139 0.014
regulation of cysteine type endopeptidase activity GO:2000116 27 0.014
adherens junction organization GO:0034332 27 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
protein ubiquitination GO:0016567 70 0.014
single organism catabolic process GO:0044712 228 0.014
sperm individualization GO:0007291 48 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
cell growth GO:0016049 108 0.014
pattern recognition receptor signaling pathway GO:0002221 2 0.014
heterocycle catabolic process GO:0046700 166 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
forebrain development GO:0030900 2 0.014
nuclear division GO:0000280 332 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
positive regulation of signaling GO:0023056 243 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of programmed cell death GO:0043067 152 0.013
circulatory system development GO:0072359 82 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
response to radiation GO:0009314 155 0.013
epithelial cell development GO:0002064 274 0.013
cell proliferation GO:0008283 299 0.013
regulation of cell development GO:0060284 215 0.013
protein localization GO:0008104 284 0.013
programmed cell death GO:0012501 257 0.013
ovarian follicle cell development GO:0030707 248 0.013
positive regulation of protein modification process GO:0031401 58 0.013
regulation of chitin based cuticle tanning GO:0007564 14 0.013
organelle assembly GO:0070925 198 0.013
establishment of localization in cell GO:0051649 402 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
peptidyl threonine modification GO:0018210 3 0.013
lateral inhibition GO:0046331 206 0.013
cell junction assembly GO:0034329 42 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
actin filament based process GO:0030029 220 0.013
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regulation of catabolic process GO:0009894 170 0.013
morphogenesis of a branching epithelium GO:0061138 45 0.013
signal transduction by phosphorylation GO:0023014 107 0.012
chorion containing eggshell formation GO:0007304 105 0.012
muscle structure development GO:0061061 224 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
regulation of cell fate specification GO:0042659 27 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
regulation of actin filament based process GO:0032970 42 0.012
pigmentation GO:0043473 75 0.012
genital disc development GO:0035215 44 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
nucleotide metabolic process GO:0009117 161 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
detection of light stimulus GO:0009583 58 0.012
convergent extension GO:0060026 2 0.012
nucleus organization GO:0006997 45 0.012
membrane organization GO:0061024 112 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
branching morphogenesis of an epithelial tube GO:0048754 45 0.012
aminoglycan metabolic process GO:0006022 18 0.012
regulation of protein transport GO:0051223 57 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
protein processing GO:0016485 68 0.012
divalent inorganic cation transport GO:0072511 30 0.012
developmental maturation GO:0021700 172 0.012
regulation of cholesterol transport GO:0032374 1 0.012
developmental cell growth GO:0048588 52 0.012
spinal cord development GO:0021510 1 0.012
positive regulation of cell communication GO:0010647 250 0.012
single organism nuclear import GO:1902593 51 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
peptidyl tyrosine phosphorylation GO:0018108 24 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.012
catecholamine biosynthetic process GO:0042423 3 0.012
regulation of heart contraction GO:0008016 21 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
eye development GO:0001654 323 0.012
regulation of nervous system development GO:0051960 248 0.011
hippo signaling GO:0035329 20 0.011
endoderm formation GO:0001706 3 0.011
oocyte development GO:0048599 124 0.011
chromatin remodeling GO:0006338 72 0.011
stress activated mapk cascade GO:0051403 52 0.011
cellular protein localization GO:0034613 160 0.011
macromolecular complex assembly GO:0065003 256 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
mrna metabolic process GO:0016071 124 0.011
regulation of epithelial cell migration GO:0010632 12 0.011
gastrulation GO:0007369 70 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
positive regulation of protein transport GO:0051222 37 0.011
development of primary female sexual characteristics GO:0046545 12 0.011
negative regulation of cell cycle GO:0045786 116 0.011
positive regulation of cell cycle GO:0045787 43 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
response to oxygen levels GO:0070482 59 0.011
regulation of defense response GO:0031347 102 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
regulation of oocyte development GO:0060281 27 0.011
intercellular bridge organization GO:0043063 14 0.011
aging GO:0007568 143 0.011
organophosphate metabolic process GO:0019637 195 0.011
determination of adult lifespan GO:0008340 137 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.011
multi organism behavior GO:0051705 175 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
nucleotide catabolic process GO:0009166 109 0.011
ras protein signal transduction GO:0007265 88 0.011
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
cell recognition GO:0008037 102 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
cognition GO:0050890 141 0.011
cellular homeostasis GO:0019725 80 0.011
epithelial cell migration open tracheal system GO:0007427 32 0.011
regulation of developmental growth GO:0048638 174 0.011
protein targeting GO:0006605 64 0.011
regulation of kinase activity GO:0043549 53 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
positive regulation of catabolic process GO:0009896 105 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
dna metabolic process GO:0006259 227 0.010
cellular catabolic process GO:0044248 372 0.010
carbohydrate metabolic process GO:0005975 82 0.010
developmental pigmentation GO:0048066 68 0.010
muscle cell differentiation GO:0042692 103 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
aromatic compound catabolic process GO:0019439 166 0.010
germline ring canal formation GO:0030725 13 0.010
lipid metabolic process GO:0006629 121 0.010
macromolecule glycosylation GO:0043413 32 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
negative regulation of transferase activity GO:0051348 18 0.010
detection of stimulus GO:0051606 156 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
malpighian tubule development GO:0072002 64 0.010

Megalin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
cardiovascular system disease DOID:1287 0 0.013
integumentary system disease DOID:16 0 0.012