Drosophila melanogaster

0 known processes

betaTry (Dmel_CG18211)

betaTrypsin

(Aliases: CG18211,Dmel\CG18211,DmBetaTry,Try,SP119,beta)

betaTry biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to external biotic stimulus GO:0043207 293 0.801
response to biotic stimulus GO:0009607 294 0.682
response to other organism GO:0051707 293 0.584
defense response to gram negative bacterium GO:0050829 94 0.493
immune response GO:0006955 246 0.463
innate immune response GO:0045087 144 0.412
defense response to other organism GO:0098542 225 0.368
immune system process GO:0002376 347 0.339
defense response to gram positive bacterium GO:0050830 41 0.337
response to bacterium GO:0009617 198 0.313
positive regulation of signaling GO:0023056 243 0.278
response to fungus GO:0009620 50 0.242
defense response GO:0006952 300 0.212
defense response to bacterium GO:0042742 178 0.201
toll signaling pathway GO:0008063 25 0.176
positive regulation of response to stimulus GO:0048584 323 0.125
defense response to fungus GO:0050832 48 0.118
neutral lipid biosynthetic process GO:0046460 2 0.114
positive regulation of signal transduction GO:0009967 223 0.112
gland development GO:0048732 191 0.104
regulation of sequestering of triglyceride GO:0010889 3 0.098
positive regulation of cell communication GO:0010647 250 0.094
wing disc morphogenesis GO:0007472 344 0.087
regulation of toll signaling pathway GO:0008592 17 0.086
phosphatidylethanolamine metabolic process GO:0046337 1 0.082
regulation of lipid storage GO:0010883 22 0.081
imaginal disc derived wing morphogenesis GO:0007476 337 0.078
response to copper ion GO:0046688 4 0.072
phospholipid homeostasis GO:0055091 1 0.071
acylglycerol biosynthetic process GO:0046463 2 0.068
exocrine system development GO:0035272 162 0.067
macromolecular complex assembly GO:0065003 256 0.065
anion homeostasis GO:0055081 3 0.064
cell recognition GO:0008037 102 0.064
response to organic substance GO:0010033 284 0.060
post embryonic appendage morphogenesis GO:0035120 385 0.059
death GO:0016265 284 0.058
imaginal disc derived appendage development GO:0048737 399 0.057
gland morphogenesis GO:0022612 145 0.056
appendage morphogenesis GO:0035107 397 0.052
positive regulation of sequestering of triglyceride GO:0010890 1 0.052
negative regulation of response to stimulus GO:0048585 258 0.051
imaginal disc derived appendage morphogenesis GO:0035114 395 0.050
salivary gland morphogenesis GO:0007435 145 0.047
homeostatic process GO:0042592 199 0.042
protein complex biogenesis GO:0070271 201 0.042
appendage development GO:0048736 401 0.041
sterol homeostasis GO:0055092 4 0.041
regulation of localization GO:0032879 275 0.041
cell death GO:0008219 279 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
sulfur compound metabolic process GO:0006790 59 0.039
cholesterol transport GO:0030301 2 0.038
alditol phosphate metabolic process GO:0052646 2 0.037
triglyceride catabolic process GO:0019433 3 0.037
regulation of defense response GO:0031347 102 0.036
phosphatidic acid metabolic process GO:0046473 1 0.035
carboxylic acid metabolic process GO:0019752 92 0.035
developmental growth GO:0048589 280 0.034
cellular amine metabolic process GO:0044106 12 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
growth GO:0040007 359 0.032
response to temperature stimulus GO:0009266 106 0.032
organic acid metabolic process GO:0006082 103 0.032
cellular catabolic process GO:0044248 372 0.032
positive regulation of transport GO:0051050 92 0.031
catabolic process GO:0009056 409 0.031
protein complex assembly GO:0006461 200 0.031
ethanolamine containing compound metabolic process GO:0042439 4 0.030
regulation of innate immune response GO:0045088 71 0.029
salivary gland cell autophagic cell death GO:0035071 83 0.029
developmental programmed cell death GO:0010623 138 0.028
maintenance of location GO:0051235 73 0.028
cholesterol homeostasis GO:0042632 3 0.028
cellular lipid catabolic process GO:0044242 16 0.028
regulation of immune system process GO:0002682 176 0.027
organic substance catabolic process GO:1901575 308 0.027
regulation of lipid transport GO:0032368 3 0.027
tissue death GO:0016271 102 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
glycoprotein biosynthetic process GO:0009101 41 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
vesicle mediated transport GO:0016192 381 0.025
body morphogenesis GO:0010171 2 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.024
amine metabolic process GO:0009308 12 0.024
autophagic cell death GO:0048102 83 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
lipid biosynthetic process GO:0008610 46 0.023
salivary gland development GO:0007431 162 0.023
endocytosis GO:0006897 310 0.023
response to cold GO:0009409 13 0.023
salivary gland histolysis GO:0035070 88 0.023
regulation of response to stress GO:0080134 200 0.023
neutral lipid catabolic process GO:0046461 3 0.023
lipid metabolic process GO:0006629 121 0.022
oxoacid metabolic process GO:0043436 103 0.021
small molecule biosynthetic process GO:0044283 37 0.021
phosphatidylcholine metabolic process GO:0046470 3 0.021
regulation of transport GO:0051049 181 0.021
glycerolipid catabolic process GO:0046503 3 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
single organism biosynthetic process GO:0044711 206 0.020
triglyceride biosynthetic process GO:0019432 2 0.020
regulation of immune response GO:0050776 118 0.020
glycoprotein metabolic process GO:0009100 41 0.020
protein modification process GO:0036211 438 0.020
regulation of sterol transport GO:0032371 1 0.020
organic substance transport GO:0071702 257 0.020
response to extracellular stimulus GO:0009991 116 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
cell proliferation GO:0008283 299 0.019
regulation of cell cycle GO:0051726 291 0.019
carbohydrate derivative biosynthetic process GO:1901137 85 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.019
ovarian follicle cell development GO:0030707 248 0.019
organophosphate catabolic process GO:0046434 112 0.018
response to paraquat GO:1901562 4 0.018
chemical homeostasis GO:0048878 92 0.018
negative regulation of defense response GO:0031348 35 0.018
negative regulation of signal transduction GO:0009968 206 0.018
long chain fatty acid metabolic process GO:0001676 3 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
glycerophospholipid metabolic process GO:0006650 23 0.018
sulfur compound biosynthetic process GO:0044272 16 0.018
response to oxidative stress GO:0006979 86 0.017
response to hypoxia GO:0001666 53 0.017
negative regulation of signaling GO:0023057 219 0.017
eggshell formation GO:0030703 105 0.017
response to abiotic stimulus GO:0009628 341 0.017
regulation of multi organism process GO:0043900 131 0.017
small molecule metabolic process GO:0044281 305 0.017
regulation of cholesterol transport GO:0032374 1 0.016
carboxylic acid biosynthetic process GO:0046394 15 0.016
programmed cell death GO:0012501 257 0.016
phagocytosis GO:0006909 215 0.016
positive regulation of lipid storage GO:0010884 4 0.016
cellular protein modification process GO:0006464 438 0.016
response to peptide GO:1901652 29 0.016
regulation of cell development GO:0060284 215 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of biosynthetic process GO:0009891 316 0.015
response to metal ion GO:0010038 23 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
activation of innate immune response GO:0002218 4 0.015
phosphorylation GO:0016310 294 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
response to oxygen containing compound GO:1901700 200 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
rhythmic process GO:0048511 106 0.015
histolysis GO:0007559 102 0.015
negative regulation of growth GO:0045926 84 0.015
anatomical structure homeostasis GO:0060249 97 0.014
cellular response to organic substance GO:0071310 132 0.014
neutral lipid metabolic process GO:0006638 12 0.014
organophosphate metabolic process GO:0019637 195 0.014
intracellular signal transduction GO:0035556 300 0.014
negative regulation of cell communication GO:0010648 223 0.014
proteolysis GO:0006508 192 0.014
cellular response to hormone stimulus GO:0032870 44 0.013
regulation of catabolic process GO:0009894 170 0.013
response to peptide hormone GO:0043434 29 0.013
immune response activating signal transduction GO:0002757 2 0.013
epithelial cell differentiation GO:0030855 322 0.013
regulation of cell death GO:0010941 173 0.013
monocarboxylic acid metabolic process GO:0032787 29 0.013
blastoderm segmentation GO:0007350 159 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
response to nutrient levels GO:0031667 114 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
cellular modified amino acid metabolic process GO:0006575 45 0.012
ion homeostasis GO:0050801 55 0.012
segmentation GO:0035282 207 0.012
epithelial cell development GO:0002064 274 0.012
establishment of planar polarity GO:0001736 87 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
response to lipopolysaccharide GO:0032496 4 0.012
regulation of cell differentiation GO:0045595 302 0.012
morphogenesis of a polarized epithelium GO:0001738 93 0.012
synapse organization GO:0050808 196 0.012
cell division GO:0051301 248 0.011
synapse assembly GO:0007416 143 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
apoptotic process GO:0006915 159 0.011
mitotic nuclear division GO:0007067 213 0.011
regulation of catalytic activity GO:0050790 185 0.011
lipid localization GO:0010876 54 0.011
response to calcium ion GO:0051592 1 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
response to decreased oxygen levels GO:0036293 58 0.011
negative regulation of developmental process GO:0051093 201 0.011
cellular lipid metabolic process GO:0044255 83 0.011
tissue morphogenesis GO:0048729 297 0.011
eggshell chorion assembly GO:0007306 66 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
response to oxygen levels GO:0070482 59 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
lipid homeostasis GO:0055088 33 0.010
circadian rhythm GO:0007623 105 0.010
acylglycerol homeostasis GO:0055090 19 0.010
compound eye morphogenesis GO:0001745 249 0.010
regulation of protein metabolic process GO:0051246 256 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010

betaTry disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
familial lipoprotein lipase deficiency DOID:14118 0 0.129
disease of metabolism DOID:0014667 0 0.129
familial hyperlipidemia DOID:1168 0 0.129
lipid metabolism disorder DOID:3146 0 0.129
inherited metabolic disorder DOID:655 0 0.129
familial combined hyperlipidemia DOID:13809 0 0.121
hair disease DOID:421 0 0.120
disease of anatomical entity DOID:7 0 0.120
integumentary system disease DOID:16 0 0.120
acquired metabolic disease DOID:0060158 0 0.092
carbohydrate metabolism disease DOID:0050013 0 0.062
glucose metabolism disease DOID:4194 0 0.062
hypotrichosis DOID:4535 0 0.049
amyloidosis DOID:9120 0 0.037
familial visceral amyloidosis DOID:0050636 0 0.037
diabetes mellitus DOID:9351 0 0.020
type 2 diabetes mellitus DOID:9352 0 0.020
nervous system disease DOID:863 0 0.012
familial hypertriglyceridemia DOID:0050527 0 0.011