Drosophila melanogaster

155 known processes

mor (Dmel_CG18740)

moira

(Aliases: Dmel\CG18740,dmMOIRA,CG18740,MOR,Moira,MOR/BAP155,Swi3D,E(E2F)3B,BAP155,l(3)89B1,Mor,CG4275)

mor biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 266 0.995
positive regulation of rna metabolic process GO:0051254 271 0.992
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.980
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.975
Human Mouse
positive regulation of gene expression GO:0010628 290 0.973
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.971
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.971
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.970
negative regulation of gene expression GO:0010629 387 0.969
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.969
positive regulation of nucleic acid templated transcription GO:1903508 266 0.950
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.947
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.933
Human Mouse
reproductive system development GO:0061458 74 0.933
Worm
negative regulation of cellular biosynthetic process GO:0031327 277 0.914
Human Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.909
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.886
Human Mouse
axon development GO:0061564 297 0.882
embryo development ending in birth or egg hatching GO:0009792 152 0.880
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.862
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.816
Human Mouse
regionalization GO:0003002 416 0.815
positive regulation of biosynthetic process GO:0009891 316 0.797
imaginal disc derived appendage development GO:0048737 399 0.776
negative regulation of transcription dna templated GO:0045892 237 0.762
Human Mouse
regulation of cell differentiation GO:0045595 302 0.759
post embryonic appendage morphogenesis GO:0035120 385 0.743
appendage morphogenesis GO:0035107 397 0.707
stem cell maintenance GO:0019827 67 0.702
transcription from rna polymerase ii promoter GO:0006366 368 0.671
Mouse
chromosome organization GO:0051276 360 0.643
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.641
sex differentiation GO:0007548 81 0.621
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.601
Human Mouse
gonad development GO:0008406 50 0.568
Worm
negative regulation of cellular metabolic process GO:0031324 382 0.553
Human Mouse
development of primary sexual characteristics GO:0045137 50 0.512
Worm
segmentation GO:0035282 207 0.464
appendage development GO:0048736 401 0.458
body morphogenesis GO:0010171 2 0.446
protein dna complex subunit organization GO:0071824 86 0.436
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.412
embryonic pattern specification GO:0009880 174 0.392
protein modification process GO:0036211 438 0.388
regulation of rna splicing GO:0043484 69 0.377
neuron projection guidance GO:0097485 241 0.362
negative regulation of neuroblast proliferation GO:0007406 27 0.356
regulation of intracellular signal transduction GO:1902531 236 0.354
axonogenesis GO:0007409 290 0.342
negative regulation of biosynthetic process GO:0009890 277 0.341
Human Mouse
sensory organ morphogenesis GO:0090596 260 0.329
reproductive structure development GO:0048608 74 0.309
Worm
anterior posterior pattern specification GO:0009952 136 0.299
axon guidance GO:0007411 233 0.298
eye photoreceptor cell differentiation GO:0001754 145 0.287
stem cell differentiation GO:0048863 117 0.283
cellular response to organic substance GO:0071310 132 0.282
Mouse
chromatin modification GO:0016568 147 0.276
Human
negative regulation of rna metabolic process GO:0051253 251 0.269
Human Mouse
regulation of mrna metabolic process GO:1903311 72 0.260
chromatin silencing GO:0006342 76 0.255
response to organic substance GO:0010033 284 0.250
Mouse
rna splicing via transesterification reactions GO:0000375 73 0.245
axis specification GO:0009798 167 0.243
regulation of multi organism process GO:0043900 131 0.242
Worm
tube development GO:0035295 244 0.239
muscle structure development GO:0061061 224 0.236
intracellular signal transduction GO:0035556 300 0.231
cellular response to dna damage stimulus GO:0006974 223 0.226
mrna metabolic process GO:0016071 124 0.222
dna templated transcription elongation GO:0006354 18 0.212
internal protein amino acid acetylation GO:0006475 38 0.210
oocyte development GO:0048599 124 0.209
negative regulation of cell proliferation GO:0008285 69 0.206
blastoderm segmentation GO:0007350 159 0.195
atp dependent chromatin remodeling GO:0043044 22 0.192
Human
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.188
photoreceptor cell differentiation GO:0046530 170 0.186
eye development GO:0001654 323 0.185
nucleosome mobilization GO:0042766 9 0.173
peptidyl amino acid modification GO:0018193 105 0.173
cellular component assembly involved in morphogenesis GO:0010927 151 0.171
dendrite development GO:0016358 204 0.159
mrna processing GO:0006397 104 0.157
imaginal disc derived wing morphogenesis GO:0007476 337 0.152
regulation of response to stress GO:0080134 200 0.150
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.150
compound eye development GO:0048749 307 0.130
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.129
Mouse
digestive system development GO:0055123 149 0.129
multicellular organismal reproductive behavior GO:0033057 110 0.129
Worm
death GO:0016265 284 0.128
cell migration GO:0016477 238 0.125
peptidyl lysine acetylation GO:0018394 39 0.125
cell proliferation GO:0008283 299 0.120
histone lysine methylation GO:0034968 32 0.116
covalent chromatin modification GO:0016569 106 0.116
regulation of apoptotic process GO:0042981 130 0.115
posttranscriptional regulation of gene expression GO:0010608 145 0.114
regulation of mrna processing GO:0050684 71 0.113
response to oxygen containing compound GO:1901700 200 0.111
Mouse
embryonic axis specification GO:0000578 107 0.110
nucleosome organization GO:0034728 59 0.109
Human
genitalia development GO:0048806 26 0.109
Worm
regulation of neurogenesis GO:0050767 158 0.107
regulation of molecular function GO:0065009 217 0.105
stem cell development GO:0048864 79 0.104
growth GO:0040007 359 0.101
Worm
organelle assembly GO:0070925 198 0.101
macromolecular complex assembly GO:0065003 256 0.099
dendrite morphogenesis GO:0048813 199 0.098
chromatin organization GO:0006325 207 0.096
Human
methylation GO:0032259 47 0.096
cell fate determination GO:0001709 91 0.096
ras protein signal transduction GO:0007265 88 0.095
male gamete generation GO:0048232 201 0.094
regulation of localization GO:0032879 275 0.093
regulation of cell development GO:0060284 215 0.092
peptidyl lysine trimethylation GO:0018023 6 0.090
regulation of dna templated transcription elongation GO:0032784 17 0.090
larval development GO:0002164 104 0.087
Worm
cellular macromolecular complex assembly GO:0034622 153 0.086
regulation of cell proliferation GO:0042127 163 0.085
meiotic cell cycle GO:0051321 171 0.084
negative regulation of mitotic cell cycle GO:0045930 109 0.083
meiotic nuclear division GO:0007126 151 0.081
oocyte differentiation GO:0009994 145 0.081
mrna splicing via spliceosome GO:0000398 73 0.080
wing disc morphogenesis GO:0007472 344 0.080
rna localization GO:0006403 115 0.078
cell death GO:0008219 279 0.076
organonitrogen compound metabolic process GO:1901564 318 0.074
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.074
regulation of gene silencing GO:0060968 63 0.073
regulation of dna templated transcription in response to stress GO:0043620 4 0.070
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.067
histone h3 k4 methylation GO:0051568 16 0.066
small gtpase mediated signal transduction GO:0007264 88 0.066
developmental growth GO:0048589 280 0.063
Worm
rna splicing GO:0008380 83 0.063
regulation of growth GO:0040008 233 0.063
Worm
protein acylation GO:0043543 42 0.062
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.062
dorsal ventral pattern formation GO:0009953 133 0.061
multi organism reproductive behavior GO:0044705 121 0.061
Worm
pole plasm mrna localization GO:0019094 49 0.060
anterior posterior axis specification GO:0009948 109 0.059
regulation of phosphorus metabolic process GO:0051174 210 0.057
rna processing GO:0006396 147 0.056
negative regulation of developmental process GO:0051093 201 0.055
cellular response to chemical stimulus GO:0070887 199 0.055
Mouse
oviposition GO:0018991 19 0.054
Worm
leg disc morphogenesis GO:0007478 80 0.053
dna metabolic process GO:0006259 227 0.053
regulation of neuroblast proliferation GO:1902692 34 0.053
dna templated transcription initiation GO:0006352 25 0.053
enzyme linked receptor protein signaling pathway GO:0007167 179 0.052
Mouse
cellular component disassembly GO:0022411 46 0.052
Human
programmed cell death GO:0012501 257 0.052
regulation of mrna splicing via spliceosome GO:0048024 64 0.052
regulation of protein metabolic process GO:0051246 256 0.052
Mouse
epithelial cell differentiation GO:0030855 322 0.051
digestive tract development GO:0048565 149 0.051
cellular protein modification process GO:0006464 438 0.051
negative regulation of organelle organization GO:0010639 56 0.050
regulation of cell cycle process GO:0010564 181 0.050
imaginal disc derived leg morphogenesis GO:0007480 80 0.050
regulation of cellular response to stress GO:0080135 89 0.049
camera type eye development GO:0043010 4 0.049
protein alkylation GO:0008213 43 0.047
positive regulation of response to stimulus GO:0048584 323 0.045
positive regulation of cell proliferation GO:0008284 47 0.045
regulation of cellular amine metabolic process GO:0033238 3 0.045
alternative mrna splicing via spliceosome GO:0000380 60 0.044
morphogenesis of an epithelium GO:0002009 276 0.044
Worm
oocyte axis specification GO:0007309 108 0.043
regulation of cellular ketone metabolic process GO:0010565 3 0.043
regulation of cellular amino acid metabolic process GO:0006521 0 0.043
tripartite regional subdivision GO:0007351 103 0.043
prostaglandin biosynthetic process GO:0001516 1 0.042
regulation of reproductive process GO:2000241 54 0.041
Worm
response to alcohol GO:0097305 95 0.041
regulation of nervous system development GO:0051960 248 0.040
histone methylation GO:0016571 40 0.040
peptidyl lysine modification GO:0018205 57 0.038
neuron recognition GO:0008038 101 0.038
cell division GO:0051301 248 0.038
protein localization to chromatin GO:0071168 3 0.037
forebrain development GO:0030900 2 0.036
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.036
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.035
compound eye photoreceptor cell differentiation GO:0001751 140 0.035
regulation of chromatin modification GO:1903308 28 0.034
immune system process GO:0002376 347 0.034
myofibril assembly GO:0030239 36 0.034
negative regulation of nucleoside metabolic process GO:0045978 1 0.033
dorsal ventral axis specification GO:0009950 66 0.032
regulation of cell death GO:0010941 173 0.031
cell cycle checkpoint GO:0000075 95 0.031
wnt signaling pathway GO:0016055 98 0.030
regulation of phosphate metabolic process GO:0019220 210 0.029
regulation of protein modification process GO:0031399 112 0.029
dna packaging GO:0006323 91 0.029
response to abiotic stimulus GO:0009628 341 0.028
regulation of organelle organization GO:0033043 196 0.028
cellular response to endogenous stimulus GO:0071495 80 0.027
Mouse
purine ribonucleoside catabolic process GO:0046130 112 0.027
oocyte construction GO:0007308 112 0.027
response to external biotic stimulus GO:0043207 293 0.027
negative regulation of cell cycle GO:0045786 116 0.027
cellular response to oxygen containing compound GO:1901701 79 0.027
Mouse
cellular ketone metabolic process GO:0042180 24 0.027
mitotic cell cycle phase transition GO:0044772 138 0.026
eye morphogenesis GO:0048592 260 0.025
amine metabolic process GO:0009308 12 0.025
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.025
chromosome segregation GO:0007059 157 0.025
embryonic morphogenesis GO:0048598 206 0.025
protein acetylation GO:0006473 39 0.025
multicellular organism growth GO:0035264 46 0.025
Worm
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.025
gland development GO:0048732 191 0.025
glial cell fate determination GO:0007403 3 0.024
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.024
spermatogenesis GO:0007283 200 0.024
mitotic g2 m transition checkpoint GO:0044818 70 0.024
developmental programmed cell death GO:0010623 138 0.023
localization of cell GO:0051674 257 0.023
regulation of phosphorylation GO:0042325 147 0.023
positive regulation of signal transduction GO:0009967 223 0.023
eggshell chorion assembly GO:0007306 66 0.023
macromolecule methylation GO:0043414 45 0.022
dendrite guidance GO:0070983 21 0.022
g2 dna damage checkpoint GO:0031572 69 0.022
regulation of meiosis GO:0040020 3 0.022
chromatin remodeling GO:0006338 72 0.022
Human
cellular response to lipid GO:0071396 20 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
negative regulation of neural precursor cell proliferation GO:2000178 27 0.021
response to endogenous stimulus GO:0009719 119 0.021
Mouse
positive regulation of growth GO:0045927 75 0.020
Worm
spliceosomal complex assembly GO:0000245 1 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
embryonic organ development GO:0048568 50 0.020
intermediate filament based process GO:0045103 1 0.020
regulation of response to gamma radiation GO:2001228 4 0.019
regulation of programmed cell death GO:0043067 152 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
neuron fate commitment GO:0048663 50 0.019
Mouse
chemotaxis GO:0006935 249 0.018
cellular macromolecule localization GO:0070727 220 0.018
dna integrity checkpoint GO:0031570 81 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
apoptotic process GO:0006915 159 0.018
gene silencing GO:0016458 138 0.018
reproductive behavior GO:0019098 122 0.018
Worm
head development GO:0060322 135 0.018
Mouse
leg disc development GO:0035218 92 0.017
negative regulation of programmed cell death GO:0043069 72 0.017
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.017
response to lipid GO:0033993 38 0.017
positive regulation of transport GO:0051050 92 0.017
histone acetylation GO:0016573 38 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
gland morphogenesis GO:0022612 145 0.017
histone modification GO:0016570 106 0.017
cellular amine metabolic process GO:0044106 12 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
phagocytosis GO:0006909 215 0.016
ameboidal type cell migration GO:0001667 151 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
regulation of sister chromatid cohesion GO:0007063 2 0.016
tube morphogenesis GO:0035239 191 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
small molecule metabolic process GO:0044281 305 0.016
multi organism behavior GO:0051705 175 0.016
Worm
eggshell formation GO:0030703 105 0.015
positive regulation of signaling GO:0023056 243 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
extrinsic apoptotic signaling pathway GO:0097191 1 0.015
eye photoreceptor cell development GO:0042462 81 0.015
organic acid metabolic process GO:0006082 103 0.015
cell adhesion GO:0007155 136 0.015
cell type specific apoptotic process GO:0097285 38 0.015
negative regulation of apoptotic process GO:0043066 63 0.015
cellular response to hormone stimulus GO:0032870 44 0.015
Mouse
regulation of cell cycle GO:0051726 291 0.015
positive regulation of ras protein signal transduction GO:0046579 43 0.015
regulation of hemocyte proliferation GO:0035206 37 0.014
convergent extension GO:0060026 2 0.014
protein localization GO:0008104 284 0.014
endocytosis GO:0006897 310 0.014
salivary gland development GO:0007431 162 0.014
meiotic nuclear envelope disassembly GO:0051078 2 0.014
regulation of wnt signaling pathway GO:0030111 68 0.014
stress granule disassembly GO:0035617 1 0.014
negative regulation of nucleotide metabolic process GO:0045980 4 0.014
spermatid differentiation GO:0048515 114 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
positive regulation of neuron projection regeneration GO:0070572 3 0.014
dna methylation GO:0006306 4 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.014
camera type eye morphogenesis GO:0048593 2 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 9 0.014
regulation of neuron differentiation GO:0045664 103 0.013
compound eye morphogenesis GO:0001745 249 0.013
mitochondrial membrane organization GO:0007006 3 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.013
regulation of chromatin silencing GO:0031935 36 0.013
cellular protein localization GO:0034613 160 0.013
positive regulation of protein modification process GO:0031401 58 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
histolysis GO:0007559 102 0.012
formation of a compartment boundary GO:0060288 4 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.012
epithelial cell development GO:0002064 274 0.012
internal peptidyl lysine acetylation GO:0018393 38 0.012
retina development in camera type eye GO:0060041 4 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
cellular respiration GO:0045333 26 0.011
ovarian follicle cell development GO:0030707 248 0.011
salivary gland histolysis GO:0035070 88 0.011
regulation of response to dna damage stimulus GO:2001020 23 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
regulation of cell shape GO:0008360 113 0.011
organelle fission GO:0048285 340 0.011
digestive tract morphogenesis GO:0048546 127 0.011
photoreceptor cell development GO:0042461 96 0.011
disaccharide metabolic process GO:0005984 4 0.011
muscle organ development GO:0007517 127 0.011
regulation of catalytic activity GO:0050790 185 0.011
icosanoid biosynthetic process GO:0046456 1 0.011
hindbrain development GO:0030902 2 0.011
negative regulation of gtp catabolic process GO:0033125 1 0.011
limb morphogenesis GO:0035108 1 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
positive regulation of ruffle assembly GO:1900029 1 0.010
autophagic cell death GO:0048102 83 0.010
dna damage checkpoint GO:0000077 78 0.010
negative regulation of cell death GO:0060548 81 0.010
striated muscle cell development GO:0055002 50 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
negative regulation of transcription factor import into nucleus GO:0042992 4 0.010
intracellular receptor signaling pathway GO:0030522 19 0.010
cell maturation GO:0048469 144 0.010

mor disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.010