Drosophila melanogaster

8 known processes

TORC (Dmel_CG6064)

CG6064 gene product from transcript CG6064-RA

(Aliases: Dmel\CG6064,CG6064,dTORC)

TORC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification process GO:0036211 438 0.295
regulation of cell death GO:0010941 173 0.295
growth GO:0040007 359 0.252
programmed cell death GO:0012501 257 0.245
defense response GO:0006952 300 0.242
regulation of cell differentiation GO:0045595 302 0.234
lateral inhibition GO:0046331 206 0.227
multi organism behavior GO:0051705 175 0.217
regulation of response to stress GO:0080134 200 0.210
regulation of cellular protein metabolic process GO:0032268 243 0.179
negative regulation of signaling GO:0023057 219 0.178
cellular protein modification process GO:0006464 438 0.158
cell cell signaling involved in cell fate commitment GO:0045168 210 0.147
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.143
regulation of protein metabolic process GO:0051246 256 0.143
photoreceptor cell differentiation GO:0046530 170 0.141
cellular response to dna damage stimulus GO:0006974 223 0.124
regulation of defense response GO:0031347 102 0.121
wing disc morphogenesis GO:0007472 344 0.119
taxis GO:0042330 304 0.119
response to oxidative stress GO:0006979 86 0.117
negative regulation of gene expression GO:0010629 387 0.112
appendage morphogenesis GO:0035107 397 0.110
compound eye photoreceptor development GO:0042051 78 0.097
forebrain development GO:0030900 2 0.093
phosphorylation GO:0016310 294 0.093
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.085
positive regulation of macromolecule metabolic process GO:0010604 405 0.085
eye development GO:0001654 323 0.083
response to nutrient levels GO:0031667 114 0.082
negative regulation of programmed cell death GO:0043069 72 0.081
small molecule metabolic process GO:0044281 305 0.080
regulation of gene expression epigenetic GO:0040029 128 0.079
imaginal disc derived appendage development GO:0048737 399 0.079
response to starvation GO:0042594 97 0.078
response to radiation GO:0009314 155 0.078
cell death GO:0008219 279 0.077
negative regulation of cell communication GO:0010648 223 0.076
dna metabolic process GO:0006259 227 0.076
death GO:0016265 284 0.075
peptidyl amino acid modification GO:0018193 105 0.074
negative regulation of signal transduction GO:0009968 206 0.073
regulation of catalytic activity GO:0050790 185 0.072
chromosome organization GO:0051276 360 0.072
gene silencing GO:0016458 138 0.071
response to abiotic stimulus GO:0009628 341 0.070
post embryonic appendage morphogenesis GO:0035120 385 0.070
vesicle mediated transport GO:0016192 381 0.066
compound eye photoreceptor cell differentiation GO:0001751 140 0.066
imaginal disc fusion GO:0046528 19 0.064
adult behavior GO:0030534 137 0.064
regulation of intracellular signal transduction GO:1902531 236 0.062
regulation of programmed cell death GO:0043067 152 0.062
compound eye morphogenesis GO:0001745 249 0.062
columnar cuboidal epithelial cell development GO:0002066 249 0.060
chromatin remodeling GO:0006338 72 0.060
response to biotic stimulus GO:0009607 294 0.060
response to external biotic stimulus GO:0043207 293 0.059
imaginal disc derived wing morphogenesis GO:0007476 337 0.057
negative regulation of cellular metabolic process GO:0031324 382 0.057
protein phosphorylation GO:0006468 169 0.056
positive regulation of response to stimulus GO:0048584 323 0.055
regulation of phosphorus metabolic process GO:0051174 210 0.055
appendage development GO:0048736 401 0.054
eye morphogenesis GO:0048592 260 0.053
chromatin silencing GO:0006342 76 0.052
telencephalon development GO:0021537 2 0.052
regulation of molecular function GO:0065009 217 0.052
regulation of cellular ketone metabolic process GO:0010565 3 0.052
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
positive regulation of cellular protein metabolic process GO:0032270 118 0.052
response to other organism GO:0051707 293 0.051
chemical homeostasis GO:0048878 92 0.051
negative regulation of cellular biosynthetic process GO:0031327 277 0.050
response to wounding GO:0009611 94 0.050
negative regulation of cell death GO:0060548 81 0.049
establishment of localization in cell GO:0051649 402 0.049
positive regulation of transcription dna templated GO:0045893 266 0.049
regulation of cell development GO:0060284 215 0.049
positive regulation of protein modification process GO:0031401 58 0.049
negative regulation of apoptotic process GO:0043066 63 0.049
regulation of cell morphogenesis GO:0022604 163 0.048
cell growth GO:0016049 108 0.048
regulation of cellular amino acid metabolic process GO:0006521 0 0.047
purine nucleotide catabolic process GO:0006195 109 0.047
brain development GO:0007420 120 0.047
signal transduction by p53 class mediator GO:0072331 6 0.047
protein modification by small protein conjugation or removal GO:0070647 106 0.047
actin filament bundle organization GO:0061572 28 0.047
regulation of protein modification process GO:0031399 112 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.046
negative regulation of response to stimulus GO:0048585 258 0.046
cell migration GO:0016477 238 0.046
regulation of cellular amine metabolic process GO:0033238 3 0.045
regulation of cellular component biogenesis GO:0044087 201 0.044
eye photoreceptor cell development GO:0042462 81 0.044
macromolecular complex assembly GO:0065003 256 0.044
regulation of phosphorylation GO:0042325 147 0.043
positive regulation of signal transduction GO:0009967 223 0.043
positive regulation of protein metabolic process GO:0051247 128 0.043
intrinsic apoptotic signaling pathway GO:0097193 16 0.042
positive regulation of phosphate metabolic process GO:0045937 139 0.041
protein modification by small protein conjugation GO:0032446 79 0.041
neutral lipid biosynthetic process GO:0046460 2 0.041
regulation of nervous system development GO:0051960 248 0.041
chemotaxis GO:0006935 249 0.040
negative regulation of biosynthetic process GO:0009890 277 0.040
regulation of transferase activity GO:0051338 58 0.040
apoptotic process GO:0006915 159 0.040
axon development GO:0061564 297 0.039
regulation of localization GO:0032879 275 0.039
regulation of multicellular organismal development GO:2000026 414 0.038
synapse organization GO:0050808 196 0.038
synaptic transmission GO:0007268 288 0.038
negative regulation of developmental process GO:0051093 201 0.037
regulation of immune system process GO:0002682 176 0.037
defense response to bacterium GO:0042742 178 0.037
heterocycle catabolic process GO:0046700 166 0.037
amine metabolic process GO:0009308 12 0.036
nuclear division GO:0000280 332 0.036
central nervous system development GO:0007417 201 0.036
negative regulation of rna metabolic process GO:0051253 251 0.035
regulation of phosphate metabolic process GO:0019220 210 0.035
aromatic compound catabolic process GO:0019439 166 0.035
intracellular signal transduction GO:0035556 300 0.035
single organism catabolic process GO:0044712 228 0.034
regulation of protein phosphorylation GO:0001932 64 0.034
peptidyl tyrosine phosphorylation GO:0018108 24 0.034
negative regulation of rna biosynthetic process GO:1902679 240 0.034
positive regulation of molecular function GO:0044093 136 0.034
ovarian follicle cell development GO:0030707 248 0.034
regulation of protein kinase activity GO:0045859 51 0.033
cellular ketone metabolic process GO:0042180 24 0.033
spermatogenesis GO:0007283 200 0.033
organic acid metabolic process GO:0006082 103 0.033
chromatin modification GO:0016568 147 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
carbohydrate homeostasis GO:0033500 12 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.032
organic substance catabolic process GO:1901575 308 0.032
regulation of apoptotic process GO:0042981 130 0.032
regulation of cellular response to stress GO:0080135 89 0.032
intracellular transport GO:0046907 228 0.031
homeostatic process GO:0042592 199 0.031
single organism intracellular transport GO:1902582 207 0.031
response to organic substance GO:0010033 284 0.030
positive regulation of catabolic process GO:0009896 105 0.030
organelle fission GO:0048285 340 0.030
positive regulation of defense response GO:0031349 59 0.030
regulation of anatomical structure size GO:0090066 163 0.030
regulation of immune response GO:0050776 118 0.029
negative regulation of intracellular signal transduction GO:1902532 57 0.029
regulation of growth GO:0040008 233 0.029
immune response GO:0006955 246 0.029
cellular amine metabolic process GO:0044106 12 0.029
neurological system process GO:0050877 358 0.029
immune system process GO:0002376 347 0.029
cellular catabolic process GO:0044248 372 0.028
compound eye development GO:0048749 307 0.028
ameboidal type cell migration GO:0001667 151 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
phagocytosis GO:0006909 215 0.028
response to extracellular stimulus GO:0009991 116 0.028
positive regulation of gene expression GO:0010628 290 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
positive regulation of catalytic activity GO:0043085 118 0.028
regulation of cell cycle GO:0051726 291 0.028
oxoacid metabolic process GO:0043436 103 0.028
localization of cell GO:0051674 257 0.028
cellular amino acid metabolic process GO:0006520 61 0.027
purine nucleotide metabolic process GO:0006163 146 0.026
triglyceride biosynthetic process GO:0019432 2 0.026
positive regulation of signaling GO:0023056 243 0.026
imaginal disc derived wing vein specification GO:0007474 48 0.026
positive regulation of autophagy GO:0010508 21 0.025
extracellular structure organization GO:0043062 46 0.025
regulation of catabolic process GO:0009894 170 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
response to oxygen containing compound GO:1901700 200 0.025
imaginal disc fusion thorax closure GO:0046529 19 0.025
spermatid differentiation GO:0048515 114 0.025
regulation of response to dna damage stimulus GO:2001020 23 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
posttranscriptional gene silencing GO:0016441 46 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
defense response to other organism GO:0098542 225 0.024
peptidyl lysine modification GO:0018205 57 0.023
jnk cascade GO:0007254 50 0.023
negative regulation of cell differentiation GO:0045596 143 0.023
developmental growth GO:0048589 280 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
tissue migration GO:0090130 155 0.023
actin filament bundle assembly GO:0051017 26 0.023
lipid metabolic process GO:0006629 121 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
locomotory behavior GO:0007626 176 0.022
spermatid development GO:0007286 98 0.022
tissue death GO:0016271 102 0.022
cellular carbohydrate metabolic process GO:0044262 22 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.021
positive regulation of immune system process GO:0002684 68 0.021
organic substance transport GO:0071702 257 0.021
respiratory system development GO:0060541 213 0.021
store operated calcium entry GO:0002115 3 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.021
regulation of kinase activity GO:0043549 53 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
chromatin organization GO:0006325 207 0.021
catabolic process GO:0009056 409 0.020
regulation of phosphatase activity GO:0010921 3 0.020
regulation of organelle organization GO:0033043 196 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
positive regulation of immune response GO:0050778 63 0.019
jak stat cascade GO:0007259 49 0.019
signal transduction in response to dna damage GO:0042770 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
single organism cellular localization GO:1902580 180 0.019
photoreceptor cell development GO:0042461 96 0.019
regulation of hydrolase activity GO:0051336 97 0.019
developmental maturation GO:0021700 172 0.019
positive regulation of cell death GO:0010942 69 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
negative regulation of cell cycle process GO:0010948 109 0.018
signal transduction by phosphorylation GO:0023014 107 0.018
aging GO:0007568 143 0.018
response to heat GO:0009408 63 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
purine containing compound metabolic process GO:0072521 155 0.018
maintenance of location GO:0051235 73 0.018
positive regulation of endopeptidase activity GO:0010950 26 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
mitotic spindle organization GO:0007052 220 0.018
regulation of synapse organization GO:0050807 110 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
stress activated protein kinase signaling cascade GO:0031098 55 0.018
nucleoside catabolic process GO:0009164 112 0.018
negative regulation of molecular function GO:0044092 51 0.018
glycerolipid metabolic process GO:0046486 34 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.017
microtubule based transport GO:0010970 42 0.017
neuron projection guidance GO:0097485 241 0.017
mitotic nuclear division GO:0007067 213 0.017
negative regulation of phosphorylation GO:0042326 35 0.017
organophosphate metabolic process GO:0019637 195 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
triglyceride metabolic process GO:0006641 12 0.017
somatic muscle development GO:0007525 66 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
regulation of gene silencing GO:0060968 63 0.017
endocytosis GO:0006897 310 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
filtration diaphragm assembly GO:0036058 4 0.017
regulation of response to external stimulus GO:0032101 115 0.017
positive regulation of cell communication GO:0010647 250 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
multi organism reproductive behavior GO:0044705 121 0.017
secretion GO:0046903 109 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 5 0.016
notch signaling pathway GO:0007219 120 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
rna processing GO:0006396 147 0.016
chaeta development GO:0022416 97 0.016
purine containing compound catabolic process GO:0072523 112 0.016
peptidyl tyrosine modification GO:0018212 24 0.016
microtubule based movement GO:0007018 51 0.016
antimicrobial humoral response GO:0019730 99 0.016
negative regulation of kinase activity GO:0033673 16 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
mapk cascade GO:0000165 107 0.016
humoral immune response GO:0006959 117 0.016
cellular macromolecule localization GO:0070727 220 0.015
regulation of mapk cascade GO:0043408 92 0.015
generation of precursor metabolites and energy GO:0006091 42 0.015
sensory organ morphogenesis GO:0090596 260 0.015
ras protein signal transduction GO:0007265 88 0.015
cytoskeleton dependent intracellular transport GO:0030705 44 0.015
cellular response to nutrient levels GO:0031669 62 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
internal peptidyl lysine acetylation GO:0018393 38 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
axon guidance GO:0007411 233 0.015
posttranscriptional gene silencing by rna GO:0035194 45 0.015
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.015
response to temperature stimulus GO:0009266 106 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
response to peptide GO:1901652 29 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
epithelial cell differentiation GO:0030855 322 0.014
cellular response to organic substance GO:0071310 132 0.014
muscle tissue development GO:0060537 30 0.014
determination of adult lifespan GO:0008340 137 0.014
nucleotide catabolic process GO:0009166 109 0.014
cell proliferation GO:0008283 299 0.014
regulation of lipid metabolic process GO:0019216 15 0.014
actin cytoskeleton organization GO:0030036 206 0.014
single organism biosynthetic process GO:0044711 206 0.014
regulation of neuron differentiation GO:0045664 103 0.014
positive regulation of apoptotic process GO:0043065 47 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
axon cargo transport GO:0008088 29 0.014
positive regulation of protein phosphorylation GO:0001934 34 0.014
muscle organ development GO:0007517 127 0.013
positive regulation of jun kinase activity GO:0043507 4 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
ribosomal large subunit biogenesis GO:0042273 1 0.013
neuron death GO:0070997 27 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
r7 cell differentiation GO:0045466 43 0.013
protein ubiquitination GO:0016567 70 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
organelle localization GO:0051640 148 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
positive regulation of cell motility GO:2000147 3 0.013
wound healing GO:0042060 75 0.013
regulation of peptidase activity GO:0052547 39 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
meiotic cell cycle GO:0051321 171 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
skeletal muscle fiber development GO:0048741 3 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
response to endogenous stimulus GO:0009719 119 0.013
negative regulation of protein phosphorylation GO:0001933 17 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
negative regulation of response to external stimulus GO:0032102 22 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
regulation of response to nutrient levels GO:0032107 18 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
cytoplasmic transport GO:0016482 130 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
regulation of cellular component size GO:0032535 98 0.012
regulation of transport GO:0051049 181 0.012
tube development GO:0035295 244 0.012
spindle organization GO:0007051 253 0.012
regulation of cell size GO:0008361 63 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
cell type specific apoptotic process GO:0097285 38 0.012
multicellular organismal aging GO:0010259 140 0.012
chemosensory behavior GO:0007635 106 0.012
regulation of developmental growth GO:0048638 174 0.012
germ line stem cell maintenance GO:0030718 50 0.012
regulation of neuron death GO:1901214 26 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
cell motility GO:0048870 251 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of peptidase activity GO:0010952 29 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
gtp catabolic process GO:0006184 72 0.011
positive regulation of transferase activity GO:0051347 26 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
protein localization GO:0008104 284 0.011
mitotic dna damage checkpoint GO:0044773 74 0.011
circadian rhythm GO:0007623 105 0.011
response to ionizing radiation GO:0010212 32 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.011
central nervous system neuron differentiation GO:0021953 8 0.011
embryonic morphogenesis GO:0048598 206 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
actin filament based process GO:0030029 220 0.011
response to hexose GO:0009746 3 0.011
compound eye cone cell differentiation GO:0042675 13 0.011
regulation of multi organism process GO:0043900 131 0.011
cellular response to starvation GO:0009267 61 0.011
neutral lipid metabolic process GO:0006638 12 0.011
proteolysis GO:0006508 192 0.011
cardiac cell fate specification GO:0060912 10 0.011
polyol biosynthetic process GO:0046173 3 0.011
negative regulation of protein modification process GO:0031400 29 0.011
protein complex assembly GO:0006461 200 0.011
axonogenesis GO:0007409 290 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
cellular response to endogenous stimulus GO:0071495 80 0.010
positive regulation of innate immune response GO:0045089 38 0.010
activation of innate immune response GO:0002218 4 0.010
nucleotide metabolic process GO:0009117 161 0.010
connective tissue development GO:0061448 3 0.010
embryonic hemopoiesis GO:0035162 26 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
oxidation reduction process GO:0055114 123 0.010
developmental programmed cell death GO:0010623 138 0.010
regulation of stress activated mapk cascade GO:0032872 41 0.010
regulation of neurogenesis GO:0050767 158 0.010
innate immune response GO:0045087 144 0.010

TORC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
disease of anatomical entity DOID:7 0 0.016
diabetes mellitus DOID:9351 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
acquired metabolic disease DOID:0060158 0 0.014
nervous system disease DOID:863 0 0.011