Drosophila melanogaster

83 known processes

Sirt6 (Dmel_CG6284)

CG6284 gene product from transcript CG6284-RA

(Aliases: D.mel4,Dmel\CG6284,CG6284,dSIRT6,dmSRT408)

Sirt6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic nuclear division GO:0007067 213 0.121
compound eye development GO:0048749 307 0.095
male gamete generation GO:0048232 201 0.067
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.065
organelle fission GO:0048285 340 0.040
response to external biotic stimulus GO:0043207 293 0.039
catabolic process GO:0009056 409 0.039
response to biotic stimulus GO:0009607 294 0.038
heterocycle catabolic process GO:0046700 166 0.037
growth GO:0040007 359 0.034
Rat
positive regulation of signal transduction GO:0009967 223 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.033
compound eye morphogenesis GO:0001745 249 0.033
cellular protein localization GO:0034613 160 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
cellular nitrogen compound catabolic process GO:0044270 165 0.031
negative regulation of cellular biosynthetic process GO:0031327 277 0.031
alternative mrna splicing via spliceosome GO:0000380 60 0.031
chromosome organization GO:0051276 360 0.030
Human
cellular catabolic process GO:0044248 372 0.030
negative regulation of response to stimulus GO:0048585 258 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
nuclear division GO:0000280 332 0.028
eye morphogenesis GO:0048592 260 0.027
negative regulation of cell cycle GO:0045786 116 0.027
negative regulation of cell communication GO:0010648 223 0.026
protein modification process GO:0036211 438 0.026
Human Rat
negative regulation of signaling GO:0023057 219 0.026
macromolecular complex assembly GO:0065003 256 0.026
organic substance catabolic process GO:1901575 308 0.026
spermatogenesis GO:0007283 200 0.024
negative regulation of gene expression GO:0010629 387 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
sister chromatid segregation GO:0000819 92 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
cellular macromolecule localization GO:0070727 220 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
r7 cell differentiation GO:0045466 43 0.021
sensory organ morphogenesis GO:0090596 260 0.020
mrna metabolic process GO:0016071 124 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
intracellular signal transduction GO:0035556 300 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
developmental programmed cell death GO:0010623 138 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
positive regulation of cell communication GO:0010647 250 0.018
regulation of rna splicing GO:0043484 69 0.018
negative regulation of signal transduction GO:0009968 206 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
positive regulation of growth GO:0045927 75 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
organic cyclic compound catabolic process GO:1901361 168 0.016
positive regulation of signaling GO:0023056 243 0.016
dendrite morphogenesis GO:0048813 199 0.016
developmental growth involved in morphogenesis GO:0060560 65 0.016
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
aromatic compound catabolic process GO:0019439 166 0.015
protein localization GO:0008104 284 0.015
positive regulation of developmental process GO:0051094 143 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
positive regulation of gene expression GO:0010628 290 0.015
regulation of mrna splicing via spliceosome GO:0048024 64 0.015
eye development GO:0001654 323 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
macromolecule catabolic process GO:0009057 161 0.014
proteolysis GO:0006508 192 0.014
ras protein signal transduction GO:0007265 88 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
compound eye photoreceptor development GO:0042051 78 0.014
organonitrogen compound metabolic process GO:1901564 318 0.013
purine containing compound catabolic process GO:0072523 112 0.013
body morphogenesis GO:0010171 2 0.013
rho protein signal transduction GO:0007266 14 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
developmental growth GO:0048589 280 0.013
Rat
locomotory behavior GO:0007626 176 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
response to other organism GO:0051707 293 0.012
chromatin remodeling GO:0006338 72 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of photoreceptor cell differentiation GO:0046532 34 0.012
dna metabolic process GO:0006259 227 0.012
Human
regulation of protein metabolic process GO:0051246 256 0.012
small molecule metabolic process GO:0044281 305 0.012
purine containing compound metabolic process GO:0072521 155 0.011
regulation of cell proliferation GO:0042127 163 0.011
regulation of nervous system development GO:0051960 248 0.011
cellular response to organic substance GO:0071310 132 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
spindle organization GO:0007051 253 0.011
nucleoside metabolic process GO:0009116 127 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of embryonic development GO:0045995 68 0.011
regulation of organelle organization GO:0033043 196 0.011
regulation of cell projection organization GO:0031344 92 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
endocytosis GO:0006897 310 0.011
localization of cell GO:0051674 257 0.011
amine metabolic process GO:0009308 12 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
cell proliferation GO:0008283 299 0.011
eye photoreceptor cell development GO:0042462 81 0.011
rna splicing GO:0008380 83 0.010
single organism catabolic process GO:0044712 228 0.010
inter male aggressive behavior GO:0002121 60 0.010
regulation of cell differentiation GO:0045595 302 0.010
negative regulation of rna biosynthetic process GO:1902679 240 0.010

Sirt6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011