Drosophila melanogaster

69 known processes

Sas-4 (Dmel_CG10061)

CG10061 gene product from transcript CG10061-RA

(Aliases: SAS4,DSas4,SAS-4,Dmel\CG10061,Sas4,dsas-4,l(3)S2214,D-Sas4,l(3)s2214,DSas-4,CG10061,DSAS-4,sas-4)

Sas-4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome organization GO:0051297 163 0.997
organelle fission GO:0048285 340 0.993
centrosome duplication GO:0051298 121 0.991
microtubule organizing center organization GO:0031023 168 0.990
centrosome cycle GO:0007098 137 0.986
male gamete generation GO:0048232 201 0.982
mitotic spindle organization GO:0007052 220 0.982
nuclear division GO:0000280 332 0.979
centriole centriole cohesion GO:0010457 5 0.971
centrosome separation GO:0051299 20 0.969
neuroblast division GO:0055057 35 0.955
neuronal stem cell division GO:0036445 35 0.932
asymmetric neuroblast division GO:0055059 33 0.929
spermatogenesis GO:0007283 200 0.927
centriole assembly GO:0098534 24 0.924
asymmetric stem cell division GO:0098722 49 0.860
somatic stem cell division GO:0048103 37 0.860
regulation of cell cycle GO:0051726 291 0.860
spermatid differentiation GO:0048515 114 0.852
cell division GO:0051301 248 0.817
neural precursor cell proliferation GO:0061351 75 0.791
regulation of cell cycle process GO:0010564 181 0.789
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.758
meiotic nuclear division GO:0007126 151 0.732
cilium organization GO:0044782 41 0.665
meiotic cell cycle process GO:1903046 132 0.658
microtubule bundle formation GO:0001578 27 0.647
organelle assembly GO:0070925 198 0.629
neuroblast proliferation GO:0007405 74 0.626
negative regulation of cell cycle GO:0045786 116 0.592
centriole replication GO:0007099 24 0.588
mitotic nuclear division GO:0007067 213 0.578
spermatid development GO:0007286 98 0.574
stem cell division GO:0017145 69 0.538
mitotic sister chromatid segregation GO:0000070 87 0.521
establishment of localization in cell GO:0051649 402 0.505
cell proliferation GO:0008283 299 0.476
dna metabolic process GO:0006259 227 0.454
negative regulation of cellular metabolic process GO:0031324 382 0.426
negative regulation of cell cycle process GO:0010948 109 0.405
spindle organization GO:0007051 253 0.385
mitotic centrosome separation GO:0007100 8 0.334
spindle assembly involved in mitosis GO:0090307 50 0.324
chromosome segregation GO:0007059 157 0.306
cellular macromolecule localization GO:0070727 220 0.302
protein complex assembly GO:0006461 200 0.290
regulation of microtubule based process GO:0032886 49 0.268
cellular protein localization GO:0034613 160 0.263
protein localization GO:0008104 284 0.259
single organism cellular localization GO:1902580 180 0.255
organelle localization GO:0051640 148 0.241
negative regulation of rna biosynthetic process GO:1902679 240 0.236
gland development GO:0048732 191 0.229
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.223
mitotic cell cycle checkpoint GO:0007093 88 0.218
negative regulation of cell cycle phase transition GO:1901988 103 0.204
enzyme linked receptor protein signaling pathway GO:0007167 179 0.204
embryo development ending in birth or egg hatching GO:0009792 152 0.201
regulation of catalytic activity GO:0050790 185 0.199
mitotic cell cycle phase transition GO:0044772 138 0.195
establishment of cell polarity GO:0030010 40 0.195
cytoskeleton dependent cytokinesis GO:0061640 81 0.192
asymmetric cell division GO:0008356 37 0.189
protein localization to organelle GO:0033365 82 0.174
positive regulation of macromolecule metabolic process GO:0010604 405 0.164
male meiosis cytokinesis GO:0007112 26 0.163
regulation of cell division GO:0051302 72 0.153
dna conformation change GO:0071103 105 0.153
regulation of mitotic cell cycle GO:0007346 190 0.148
sister chromatid segregation GO:0000819 92 0.147
regulation of organelle organization GO:0033043 196 0.146
cell projection assembly GO:0030031 94 0.144
developmental maturation GO:0021700 172 0.140
regulation of microtubule cytoskeleton organization GO:0070507 41 0.139
male meiosis GO:0007140 52 0.133
protein dna complex assembly GO:0065004 63 0.128
g2 dna damage checkpoint GO:0031572 69 0.125
maintenance of protein location GO:0045185 28 0.124
regulation of epithelial cell proliferation GO:0050678 4 0.123
axoneme assembly GO:0035082 18 0.121
negative regulation of protein complex disassembly GO:0043242 23 0.117
negative regulation of response to stimulus GO:0048585 258 0.116
cilium morphogenesis GO:0060271 39 0.116
snrna metabolic process GO:0016073 14 0.112
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.111
development of primary sexual characteristics GO:0045137 50 0.108
mitotic g2 m transition checkpoint GO:0044818 70 0.106
nucleobase containing small molecule metabolic process GO:0055086 174 0.105
nonmotile primary cilium assembly GO:0035058 8 0.102
negative regulation of transcription dna templated GO:0045892 237 0.102
cellular component disassembly GO:0022411 46 0.099
snrna processing GO:0016180 14 0.098
nucleus localization GO:0051647 34 0.098
reproductive system development GO:0061458 74 0.097
anatomical structure homeostasis GO:0060249 97 0.095
microtubule based movement GO:0007018 51 0.093
sex differentiation GO:0007548 81 0.091
regulation of mitotic cell cycle phase transition GO:1901990 130 0.083
negative regulation of mitotic cell cycle GO:0045930 109 0.083
gland morphogenesis GO:0022612 145 0.083
organonitrogen compound metabolic process GO:1901564 318 0.081
growth GO:0040007 359 0.081
establishment of spindle orientation GO:0051294 18 0.080
protein maturation GO:0051604 71 0.080
regulation of cellular response to stress GO:0080135 89 0.078
positive regulation of catalytic activity GO:0043085 118 0.077
purine ribonucleotide metabolic process GO:0009150 145 0.075
macromolecular complex disassembly GO:0032984 37 0.073
phosphorylation GO:0016310 294 0.073
meiotic chromosome segregation GO:0045132 59 0.072
sensory perception GO:0007600 196 0.072
negative regulation of cellular component organization GO:0051129 108 0.071
regulation of molecular function GO:0065009 217 0.070
gonad development GO:0008406 50 0.070
purine containing compound catabolic process GO:0072523 112 0.070
positive regulation of signaling GO:0023056 243 0.068
regulation of dendrite development GO:0050773 37 0.067
regulation of microtubule depolymerization GO:0031114 24 0.067
stem cell proliferation GO:0072089 88 0.066
microtubule anchoring GO:0034453 11 0.065
spindle assembly GO:0051225 80 0.064
programmed cell death GO:0012501 257 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.060
meiosis i GO:0007127 59 0.060
negative regulation of protein depolymerization GO:1901880 23 0.060
negative regulation of organelle organization GO:0010639 56 0.059
regulation of protein depolymerization GO:1901879 27 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.057
nucleus organization GO:0006997 45 0.057
macromolecular complex assembly GO:0065003 256 0.057
peptidyl tyrosine phosphorylation GO:0018108 24 0.056
cell maturation GO:0048469 144 0.056
regulation of phosphorylation GO:0042325 147 0.055
mitotic chromosome condensation GO:0007076 22 0.055
cell motility GO:0048870 251 0.053
cytokinesis GO:0000910 90 0.051
small molecule metabolic process GO:0044281 305 0.051
establishment or maintenance of cell polarity GO:0007163 167 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.051
negative regulation of rna metabolic process GO:0051253 251 0.050
exocrine system development GO:0035272 162 0.050
regulation of cell cycle phase transition GO:1901987 130 0.049
cilium assembly GO:0042384 38 0.049
protein targeting GO:0006605 64 0.048
eye development GO:0001654 323 0.048
positive regulation of signal transduction GO:0009967 223 0.048
ribonucleoside triphosphate catabolic process GO:0009203 108 0.047
cellular protein modification process GO:0006464 438 0.046
single organism biosynthetic process GO:0044711 206 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.045
response to abiotic stimulus GO:0009628 341 0.044
cell adhesion GO:0007155 136 0.044
single organism cell adhesion GO:0098602 47 0.044
mitotic sister chromatid separation GO:0051306 30 0.043
attachment of spindle microtubules to kinetochore GO:0008608 5 0.042
developmental growth GO:0048589 280 0.042
larval development GO:0002164 104 0.041
response to oxidative stress GO:0006979 86 0.041
cell fate determination GO:0001709 91 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.040
purine containing compound metabolic process GO:0072521 155 0.040
regulation of mitosis GO:0007088 56 0.040
chromosome condensation GO:0030261 41 0.039
cell cycle phase transition GO:0044770 140 0.039
single organism intracellular transport GO:1902582 207 0.039
regionalization GO:0003002 416 0.039
regulation of nuclear division GO:0051783 58 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
microtubule based transport GO:0010970 42 0.036
cellular component assembly involved in morphogenesis GO:0010927 151 0.032
cellular response to dna damage stimulus GO:0006974 223 0.032
ribonucleotide metabolic process GO:0009259 145 0.032
endomembrane system organization GO:0010256 119 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
regulation of protein complex disassembly GO:0043244 29 0.031
reproductive structure development GO:0048608 74 0.031
purine ribonucleotide catabolic process GO:0009154 109 0.031
double strand break repair GO:0006302 26 0.031
neurological system process GO:0050877 358 0.030
regulation of embryonic development GO:0045995 68 0.030
embryonic morphogenesis GO:0048598 206 0.029
protein phosphorylation GO:0006468 169 0.029
ribonucleoside triphosphate metabolic process GO:0009199 119 0.029
maintenance of protein location in cell GO:0032507 26 0.029
negative regulation of epithelial cell proliferation GO:0050680 4 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
purine nucleoside triphosphate catabolic process GO:0009146 108 0.028
salivary gland development GO:0007431 162 0.028
digestive tract development GO:0048565 149 0.028
spindle localization GO:0051653 22 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
single organismal cell cell adhesion GO:0016337 45 0.027
maintenance of location GO:0051235 73 0.027
mitotic g2 dna damage checkpoint GO:0007095 69 0.027
localization of cell GO:0051674 257 0.027
apoptotic process GO:0006915 159 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
salivary gland morphogenesis GO:0007435 145 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
cellular response to chemical stimulus GO:0070887 199 0.026
regulation of hydrolase activity GO:0051336 97 0.025
protein complex biogenesis GO:0070271 201 0.025
regulation of ras protein signal transduction GO:0046578 93 0.025
glycosyl compound metabolic process GO:1901657 127 0.025
mitotic dna integrity checkpoint GO:0044774 75 0.025
pole cell formation GO:0007279 19 0.025
protein polymerization GO:0051258 42 0.024
regulation of response to stress GO:0080134 200 0.024
cystoblast division GO:0007282 10 0.024
female meiosis i GO:0007144 8 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
positive regulation of rna metabolic process GO:0051254 271 0.024
chromosome organization GO:0051276 360 0.024
regulation of apoptotic process GO:0042981 130 0.024
dna packaging GO:0006323 91 0.024
regulation of immune system process GO:0002682 176 0.024
axonogenesis GO:0007409 290 0.024
response to organic substance GO:0010033 284 0.023
catabolic process GO:0009056 409 0.023
dendrite development GO:0016358 204 0.023
regulation of cell death GO:0010941 173 0.023
regulation of protein modification process GO:0031399 112 0.023
single organism nuclear import GO:1902593 51 0.023
protein complex disassembly GO:0043241 36 0.023
cellular catabolic process GO:0044248 372 0.023
positive regulation of cell communication GO:0010647 250 0.022
mitotic spindle stabilization GO:0043148 6 0.022
golgi organization GO:0007030 66 0.022
establishment of spindle localization GO:0051293 22 0.022
cell cycle checkpoint GO:0000075 95 0.022
regulation of cell proliferation GO:0042127 163 0.022
reciprocal meiotic recombination GO:0007131 19 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
purine nucleoside catabolic process GO:0006152 112 0.022
female meiotic division GO:0007143 70 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
germ line stem cell maintenance GO:0030718 50 0.021
dna damage checkpoint GO:0000077 78 0.021
establishment of protein localization GO:0045184 163 0.021
negative regulation of apoptotic process GO:0043066 63 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
protein modification process GO:0036211 438 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.020
positive regulation of cell cycle process GO:0090068 28 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
positive regulation of protein deacetylation GO:0090312 2 0.019
protein import GO:0017038 55 0.019
ras protein signal transduction GO:0007265 88 0.019
intracellular signal transduction GO:0035556 300 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
negative regulation of cell proliferation GO:0008285 69 0.019
oocyte dorsal ventral axis specification GO:0007310 34 0.019
protein transport GO:0015031 155 0.018
negative regulation of cytoskeleton organization GO:0051494 30 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
heterocycle catabolic process GO:0046700 166 0.018
tube development GO:0035295 244 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
maintenance of location in cell GO:0051651 28 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
regulation of mitotic spindle organization GO:0060236 9 0.018
epithelial cell development GO:0002064 274 0.018
digestive tract morphogenesis GO:0048546 127 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
nucleoside catabolic process GO:0009164 112 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
mitotic cell cycle embryonic GO:0045448 38 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
multicellular organismal aging GO:0010259 140 0.017
gastrulation GO:0007369 70 0.017
developmental programmed cell death GO:0010623 138 0.016
death GO:0016265 284 0.016
genitalia development GO:0048806 26 0.016
regulation of protein metabolic process GO:0051246 256 0.016
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.016
protein import into nucleus GO:0006606 51 0.016
oocyte axis specification GO:0007309 108 0.015
cellular protein complex disassembly GO:0043624 35 0.015
nucleoside metabolic process GO:0009116 127 0.015
embryonic pattern specification GO:0009880 174 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
nucleotide metabolic process GO:0009117 161 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
cellular protein complex assembly GO:0043623 71 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.015
regulation of protein localization to nucleus GO:1900180 29 0.015
single organism membrane organization GO:0044802 93 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
positive regulation of cell cycle GO:0045787 43 0.014
aromatic compound catabolic process GO:0019439 166 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
proteolysis GO:0006508 192 0.014
cellular response to endogenous stimulus GO:0071495 80 0.014
regulation of cytokinesis GO:0032465 3 0.014
regulation of localization GO:0032879 275 0.014
chromatin silencing GO:0006342 76 0.014
locomotory behavior GO:0007626 176 0.014
organic substance catabolic process GO:1901575 308 0.014
negative regulation of developmental process GO:0051093 201 0.014
peptidyl threonine modification GO:0018210 3 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
cell cycle arrest GO:0007050 4 0.013
mitotic dna damage checkpoint GO:0044773 74 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
asymmetric protein localization GO:0008105 33 0.013
dna recombination GO:0006310 32 0.013
negative regulation of nervous system development GO:0051961 92 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of gene expression GO:0010629 387 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
dna endoreduplication GO:0042023 22 0.012
mitotic spindle midzone assembly GO:0051256 1 0.012
protein depolymerization GO:0051261 31 0.012
dna repair GO:0006281 54 0.012
negative regulation of microtubule depolymerization GO:0007026 21 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
cytoskeleton dependent intracellular transport GO:0030705 44 0.012
organic cyclic compound catabolic process GO:1901361 168 0.011
response to growth factor GO:0070848 31 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
metaphase anaphase transition of cell cycle GO:0044784 28 0.011
single organism catabolic process GO:0044712 228 0.011
tissue morphogenesis GO:0048729 297 0.011
positive regulation of protein modification process GO:0031401 58 0.011
regulation of protein processing GO:0070613 32 0.011
establishment of organelle localization GO:0051656 122 0.011
membrane organization GO:0061024 112 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
regulation of protein targeting GO:1903533 29 0.011
sperm axoneme assembly GO:0007288 13 0.011
nuclear migration GO:0007097 20 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
establishment of mitotic spindle orientation GO:0000132 13 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.011
organophosphate catabolic process GO:0046434 112 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
chemosensory behavior GO:0007635 106 0.010
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.010
positive regulation of gtpase activity GO:0043547 43 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
nucleotide catabolic process GO:0009166 109 0.010
digestive system development GO:0055123 149 0.010

Sas-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.049
disease of cellular proliferation DOID:14566 0 0.049
organ system cancer DOID:0050686 0 0.031
disease of anatomical entity DOID:7 0 0.012
physical disorder DOID:0080015 0 0.010
congenital nervous system abnormality DOID:2490 0 0.010