Drosophila melanogaster

0 known processes

m-cup (Dmel_CG11896)

mann-cup

(Aliases: CG11896,Dmel\CG11896)

m-cup biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.278
protein modification by small protein removal GO:0070646 28 0.137
positive regulation of cellular biosynthetic process GO:0031328 316 0.123
positive regulation of biosynthetic process GO:0009891 316 0.096
spermatid development GO:0007286 98 0.093
endocytosis GO:0006897 310 0.083
protein modification process GO:0036211 438 0.081
male gamete generation GO:0048232 201 0.081
protein modification by small protein conjugation or removal GO:0070647 106 0.077
cellular protein modification process GO:0006464 438 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.069
response to abiotic stimulus GO:0009628 341 0.065
spermatid differentiation GO:0048515 114 0.061
small molecule biosynthetic process GO:0044283 37 0.060
spermatogenesis GO:0007283 200 0.057
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
positive regulation of signal transduction GO:0009967 223 0.054
organic substance catabolic process GO:1901575 308 0.049
single organism biosynthetic process GO:0044711 206 0.048
protein deubiquitination GO:0016579 17 0.048
rna processing GO:0006396 147 0.047
rna splicing GO:0008380 83 0.046
catabolic process GO:0009056 409 0.046
positive regulation of transcription dna templated GO:0045893 266 0.045
notch signaling pathway GO:0007219 120 0.045
regulation of organelle organization GO:0033043 196 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.043
positive regulation of rna biosynthetic process GO:1902680 266 0.041
cellular catabolic process GO:0044248 372 0.041
negative regulation of signal transduction GO:0009968 206 0.040
regulation of protein metabolic process GO:0051246 256 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.039
regulation of notch signaling pathway GO:0008593 100 0.039
lipid biosynthetic process GO:0008610 46 0.039
cellular macromolecule catabolic process GO:0044265 136 0.038
positive regulation of signaling GO:0023056 243 0.038
cellular ketone metabolic process GO:0042180 24 0.038
vesicle mediated transport GO:0016192 381 0.037
negative regulation of gene expression GO:0010629 387 0.037
homeostatic process GO:0042592 199 0.037
regulation of localization GO:0032879 275 0.037
death GO:0016265 284 0.036
phagocytosis GO:0006909 215 0.034
negative regulation of signaling GO:0023057 219 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
organic acid metabolic process GO:0006082 103 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
positive regulation of gene expression GO:0010628 290 0.032
sperm axoneme assembly GO:0007288 13 0.032
oxoacid metabolic process GO:0043436 103 0.031
mrna metabolic process GO:0016071 124 0.030
embryonic development via the syncytial blastoderm GO:0001700 148 0.029
body morphogenesis GO:0010171 2 0.029
negative regulation of cell communication GO:0010648 223 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
cellularization GO:0007349 90 0.027
regulation of cellular ketone metabolic process GO:0010565 3 0.027
sperm individualization GO:0007291 48 0.027
response to other organism GO:0051707 293 0.027
response to external biotic stimulus GO:0043207 293 0.027
regulation of cell death GO:0010941 173 0.027
eye morphogenesis GO:0048592 260 0.026
compound eye morphogenesis GO:0001745 249 0.026
mrna processing GO:0006397 104 0.026
carboxylic acid metabolic process GO:0019752 92 0.025
programmed cell death GO:0012501 257 0.025
lipid metabolic process GO:0006629 121 0.025
oocyte differentiation GO:0009994 145 0.025
phosphorylation GO:0016310 294 0.024
aromatic compound catabolic process GO:0019439 166 0.023
intracellular signal transduction GO:0035556 300 0.023
adult behavior GO:0030534 137 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
small molecule metabolic process GO:0044281 305 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
cell death GO:0008219 279 0.022
growth GO:0040007 359 0.022
macromolecule catabolic process GO:0009057 161 0.022
cellular response to radiation GO:0071478 52 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
single organism behavior GO:0044708 391 0.021
response to oxygen containing compound GO:1901700 200 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
chemical homeostasis GO:0048878 92 0.021
secretion GO:0046903 109 0.020
cellular homeostasis GO:0019725 80 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
compound eye development GO:0048749 307 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.019
establishment of localization in cell GO:0051649 402 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
taxis GO:0042330 304 0.019
regulation of molecular function GO:0065009 217 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.018
cognition GO:0050890 141 0.018
response to lipopolysaccharide GO:0032496 4 0.018
regulation of catalytic activity GO:0050790 185 0.018
metal ion homeostasis GO:0055065 44 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
regulation of hormone levels GO:0010817 40 0.018
cilium assembly GO:0042384 38 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.017
protein catabolic process GO:0030163 101 0.017
regulation of proteolysis GO:0030162 87 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
mitotic cytokinesis GO:0000281 50 0.017
regulation of growth GO:0040008 233 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
macromolecular complex assembly GO:0065003 256 0.016
organic substance transport GO:0071702 257 0.016
response to radiation GO:0009314 155 0.016
centrosome duplication GO:0051298 121 0.016
chromosome organization GO:0051276 360 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
organelle assembly GO:0070925 198 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
mating GO:0007618 120 0.015
intracellular transport GO:0046907 228 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
sensory organ morphogenesis GO:0090596 260 0.015
nucleotide metabolic process GO:0009117 161 0.015
proteolysis GO:0006508 192 0.015
positive regulation of cell communication GO:0010647 250 0.015
positive regulation of lipid biosynthetic process GO:0046889 3 0.015
protein localization GO:0008104 284 0.015
negative regulation of developmental process GO:0051093 201 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
rrna processing GO:0006364 3 0.014
dna metabolic process GO:0006259 227 0.014
asymmetric stem cell division GO:0098722 49 0.014
response to bacterium GO:0009617 198 0.014
centrosome organization GO:0051297 163 0.014
rna catabolic process GO:0006401 37 0.014
cellular lipid metabolic process GO:0044255 83 0.014
ras protein signal transduction GO:0007265 88 0.014
chaeta development GO:0022416 97 0.014
regulation of rna splicing GO:0043484 69 0.014
fatty acid elongation GO:0030497 3 0.014
lateral inhibition GO:0046331 206 0.014
chromatin organization GO:0006325 207 0.014
response to biotic stimulus GO:0009607 294 0.014
actin cytoskeleton organization GO:0030036 206 0.013
response to organic substance GO:0010033 284 0.013
organelle fission GO:0048285 340 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
positive regulation of lipid metabolic process GO:0045834 4 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
cell proliferation GO:0008283 299 0.013
cellular protein catabolic process GO:0044257 83 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
oocyte development GO:0048599 124 0.013
pole plasm rna localization GO:0007316 52 0.013
heterocycle catabolic process GO:0046700 166 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
regionalization GO:0003002 416 0.012
mapk cascade GO:0000165 107 0.012
memory GO:0007613 94 0.012
alditol phosphate metabolic process GO:0052646 2 0.012
kidney epithelium development GO:0072073 3 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
multicellular organismal homeostasis GO:0048871 41 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
regulation of transport GO:0051049 181 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
anatomical structure homeostasis GO:0060249 97 0.012
response to light stimulus GO:0009416 124 0.012
hormone biosynthetic process GO:0042446 20 0.012
organophosphate metabolic process GO:0019637 195 0.012
positive regulation of developmental process GO:0051094 143 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
regulation of endocytosis GO:0030100 37 0.012
regulation of steroid metabolic process GO:0019218 2 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
negative regulation of transcription dna templated GO:0045892 237 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of chromosome organization GO:0033044 64 0.011
negative regulation of cell death GO:0060548 81 0.011
multi organism reproductive behavior GO:0044705 121 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
secondary metabolite biosynthetic process GO:0044550 24 0.011
nuclear division GO:0000280 332 0.011
actin filament based process GO:0030029 220 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.011
peroxisome organization GO:0007031 14 0.011
meiotic cell cycle process GO:1903046 132 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
anterior posterior pattern specification GO:0009952 136 0.011
developmental programmed cell death GO:0010623 138 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
regulation of cellular localization GO:0060341 136 0.011
cytoplasm organization GO:0007028 64 0.010
regulation of response to stress GO:0080134 200 0.010
regulation of programmed cell death GO:0043067 152 0.010
response to temperature stimulus GO:0009266 106 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
dendrite morphogenesis GO:0048813 199 0.010
learning or memory GO:0007611 141 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
eye development GO:0001654 323 0.010
negative regulation of notch signaling pathway GO:0045746 41 0.010
regulation of secretion GO:0051046 44 0.010
centrosome cycle GO:0007098 137 0.010

m-cup disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.104
nervous system disease DOID:863 0 0.064
sensory system disease DOID:0050155 0 0.027
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.011