Drosophila melanogaster

117 known processes

trbl (Dmel_CG5408)

tribbles

(Aliases: trb,Dmel\CG5408,CG5408)

trbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell development GO:0030707 248 0.899
single organism behavior GO:0044708 391 0.817
memory GO:0007613 94 0.765
cell division GO:0051301 248 0.730
neurological system process GO:0050877 358 0.663
cognition GO:0050890 141 0.611
dna metabolic process GO:0006259 227 0.581
regulation of localization GO:0032879 275 0.578
Human Mouse
vesicle mediated transport GO:0016192 381 0.528
learning or memory GO:0007611 141 0.512
regulation of protein metabolic process GO:0051246 256 0.505
chromosome segregation GO:0007059 157 0.489
regulation of transport GO:0051049 181 0.472
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.410
programmed cell death GO:0012501 257 0.387
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.385
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.381
regulation of cellular protein metabolic process GO:0032268 243 0.369
localization of cell GO:0051674 257 0.364
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.348
glycosyl compound metabolic process GO:1901657 127 0.346
intracellular transport GO:0046907 228 0.328
regulation of cell differentiation GO:0045595 302 0.305
Mouse
growth GO:0040007 359 0.297
single organism intracellular transport GO:1902582 207 0.291
cell fate determination GO:0001709 91 0.276
long term memory GO:0007616 62 0.269
regulation of cellular localization GO:0060341 136 0.268
border follicle cell migration GO:0007298 113 0.267
nucleotide metabolic process GO:0009117 161 0.265
regulation of cell morphogenesis GO:0022604 163 0.263
regulation of anatomical structure morphogenesis GO:0022603 242 0.262
epithelial cell development GO:0002064 274 0.262
small molecule metabolic process GO:0044281 305 0.257
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.250
establishment of protein localization GO:0045184 163 0.247
response to radiation GO:0009314 155 0.247
cellular nitrogen compound catabolic process GO:0044270 165 0.244
ribonucleoside metabolic process GO:0009119 127 0.244
organelle assembly GO:0070925 198 0.237
immune system process GO:0002376 347 0.236
organelle fission GO:0048285 340 0.233
tube development GO:0035295 244 0.232
ribonucleotide metabolic process GO:0009259 145 0.219
digestive tract morphogenesis GO:0048546 127 0.217
regulation of catalytic activity GO:0050790 185 0.211
Human Mouse
regulation of intracellular signal transduction GO:1902531 236 0.210
Human
organophosphate metabolic process GO:0019637 195 0.208
purine containing compound metabolic process GO:0072521 155 0.206
negative regulation of response to stimulus GO:0048585 258 0.205
Human
stem cell development GO:0048864 79 0.204
negative regulation of developmental process GO:0051093 201 0.203
Mouse
death GO:0016265 284 0.200
Human
cell death GO:0008219 279 0.199
Human
organonitrogen compound metabolic process GO:1901564 318 0.191
carbohydrate derivative metabolic process GO:1901135 217 0.188
nucleoside phosphate metabolic process GO:0006753 162 0.183
positive regulation of protein metabolic process GO:0051247 128 0.182
regulation of organelle organization GO:0033043 196 0.180
regulation of protein modification process GO:0031399 112 0.176
negative regulation of programmed cell death GO:0043069 72 0.175
gastrulation involving germ band extension GO:0010004 36 0.172
chromosome organization GO:0051276 360 0.171
cellular response to growth factor stimulus GO:0071363 30 0.165
regulation of molecular function GO:0065009 217 0.164
Human Mouse
endocytosis GO:0006897 310 0.156
regulation of cellular component biogenesis GO:0044087 201 0.154
germ line stem cell maintenance GO:0030718 50 0.152
nucleoside triphosphate catabolic process GO:0009143 108 0.152
ribose phosphate metabolic process GO:0019693 145 0.151
ribonucleoside catabolic process GO:0042454 112 0.150
nucleobase containing compound catabolic process GO:0034655 165 0.150
aromatic compound catabolic process GO:0019439 166 0.147
purine nucleotide metabolic process GO:0006163 146 0.145
negative regulation of multicellular organismal process GO:0051241 142 0.144
Human
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.143
stem cell differentiation GO:0048863 117 0.142
macromolecular complex assembly GO:0065003 256 0.142
regulation of cellular amino acid metabolic process GO:0006521 0 0.141
purine ribonucleotide catabolic process GO:0009154 109 0.140
regulation of epithelial cell proliferation GO:0050678 4 0.138
negative regulation of cell differentiation GO:0045596 143 0.137
Mouse
secretion by cell GO:0032940 101 0.135
locomotory behavior GO:0007626 176 0.135
nucleoside metabolic process GO:0009116 127 0.135
organic substance transport GO:0071702 257 0.134
Mouse
establishment of localization in cell GO:0051649 402 0.132
spermatogenesis GO:0007283 200 0.132
nucleoside phosphate catabolic process GO:1901292 110 0.130
regulation of vesicle mediated transport GO:0060627 59 0.130
body morphogenesis GO:0010171 2 0.129
cellular response to extracellular stimulus GO:0031668 64 0.127
negative regulation of cell death GO:0060548 81 0.126
sensory organ morphogenesis GO:0090596 260 0.126
nucleotide catabolic process GO:0009166 109 0.125
regulation of gene expression epigenetic GO:0040029 128 0.123
meiotic nuclear division GO:0007126 151 0.121
purine ribonucleotide metabolic process GO:0009150 145 0.120
establishment or maintenance of cell polarity GO:0007163 167 0.119
heterocycle catabolic process GO:0046700 166 0.115
guanosine containing compound metabolic process GO:1901068 74 0.115
protein complex assembly GO:0006461 200 0.115
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.114
meiotic cell cycle GO:0051321 171 0.114
apoptotic process GO:0006915 159 0.114
Human
actin cytoskeleton organization GO:0030036 206 0.114
posttranscriptional regulation of gene expression GO:0010608 145 0.113
response to growth factor GO:0070848 31 0.112
regulation of growth GO:0040008 233 0.112
purine ribonucleoside catabolic process GO:0046130 112 0.112
ribonucleoside triphosphate metabolic process GO:0009199 119 0.112
intracellular signal transduction GO:0035556 300 0.111
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.110
positive regulation of cellular component organization GO:0051130 156 0.108
purine nucleoside catabolic process GO:0006152 112 0.107
protein modification process GO:0036211 438 0.104
purine containing compound catabolic process GO:0072523 112 0.104
ribonucleoside triphosphate catabolic process GO:0009203 108 0.104
photoreceptor cell development GO:0042461 96 0.102
developmental growth GO:0048589 280 0.102
purine nucleoside metabolic process GO:0042278 127 0.102
response to ionizing radiation GO:0010212 32 0.101
regulation of cell division GO:0051302 72 0.101
regulation of cell cycle GO:0051726 291 0.100
regulation of cell death GO:0010941 173 0.098
regulation of response to stress GO:0080134 200 0.097
embryo development ending in birth or egg hatching GO:0009792 152 0.096
negative regulation of cellular component organization GO:0051129 108 0.096
organophosphate catabolic process GO:0046434 112 0.094
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.092
protein complex biogenesis GO:0070271 201 0.090
epithelial cell differentiation GO:0030855 322 0.089
negative regulation of cell communication GO:0010648 223 0.088
Human
regulation of cellular catabolic process GO:0031329 157 0.087
positive regulation of catalytic activity GO:0043085 118 0.087
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.086
ovarian follicle cell migration GO:0007297 121 0.086
nucleoside triphosphate metabolic process GO:0009141 120 0.084
negative regulation of cell cycle GO:0045786 116 0.083
purine nucleotide catabolic process GO:0006195 109 0.081
organic cyclic compound catabolic process GO:1901361 168 0.079
secretion GO:0046903 109 0.079
positive regulation of signaling GO:0023056 243 0.078
centrosome organization GO:0051297 163 0.076
positive regulation of molecular function GO:0044093 136 0.076
Mouse
positive regulation of signal transduction GO:0009967 223 0.075
malpighian tubule development GO:0072002 64 0.075
protein localization GO:0008104 284 0.074
ribonucleotide catabolic process GO:0009261 109 0.074
gene silencing by rna GO:0031047 57 0.074
regulation of apoptotic process GO:0042981 130 0.071
negative regulation of molecular function GO:0044092 51 0.071
Human Mouse
tissue morphogenesis GO:0048729 297 0.071
mrna metabolic process GO:0016071 124 0.071
nucleus organization GO:0006997 45 0.070
eye morphogenesis GO:0048592 260 0.070
positive regulation of developmental process GO:0051094 143 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.068
cellular amine metabolic process GO:0044106 12 0.068
regulation of transferase activity GO:0051338 58 0.068
Human Mouse
digestive system development GO:0055123 149 0.068
regulation of phosphate metabolic process GO:0019220 210 0.068
Human Mouse
embryonic morphogenesis GO:0048598 206 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.067
cellular protein modification process GO:0006464 438 0.065
peptidyl amino acid modification GO:0018193 105 0.065
male gamete generation GO:0048232 201 0.065
hematopoietic or lymphoid organ development GO:0048534 57 0.064
regulation of intracellular transport GO:0032386 64 0.064
cytoplasmic transport GO:0016482 130 0.064
cellular response to endogenous stimulus GO:0071495 80 0.063
Mouse
dna replication GO:0006260 48 0.063
cellular response to ionizing radiation GO:0071479 15 0.062
catabolic process GO:0009056 409 0.060
spindle organization GO:0007051 253 0.059
negative regulation of phosphorylation GO:0042326 35 0.059
Human Mouse
taxis GO:0042330 304 0.058
sister chromatid segregation GO:0000819 92 0.058
negative regulation of cellular biosynthetic process GO:0031327 277 0.058
Human Mouse
maintenance of location in cell GO:0051651 28 0.058
nuclear division GO:0000280 332 0.057
photoreceptor cell differentiation GO:0046530 170 0.057
transcription from rna polymerase ii promoter GO:0006366 368 0.057
single fertilization GO:0007338 24 0.056
appendage development GO:0048736 401 0.056
amine metabolic process GO:0009308 12 0.056
eye photoreceptor cell differentiation GO:0001754 145 0.055
gene silencing GO:0016458 138 0.055
positive regulation of response to stimulus GO:0048584 323 0.053
positive regulation of catabolic process GO:0009896 105 0.052
positive regulation of organelle organization GO:0010638 65 0.051
negative regulation of signaling GO:0023057 219 0.051
Human
glycosyl compound catabolic process GO:1901658 112 0.050
positive regulation of multicellular organismal process GO:0051240 143 0.050
mitotic spindle organization GO:0007052 220 0.049
purine nucleoside triphosphate catabolic process GO:0009146 108 0.049
apoptotic signaling pathway GO:0097190 27 0.049
Human
immune system development GO:0002520 57 0.049
regulation of developmental growth GO:0048638 174 0.049
actin filament organization GO:0007015 126 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.048
purine nucleoside triphosphate metabolic process GO:0009144 119 0.048
cell migration GO:0016477 238 0.048
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.048
regulation of response to external stimulus GO:0032101 115 0.048
Human
cell motility GO:0048870 251 0.048
Human
purine ribonucleoside metabolic process GO:0046128 127 0.047
negative regulation of nucleic acid templated transcription GO:1903507 240 0.046
Human Mouse
mesenchymal cell development GO:0014031 1 0.046
regulation of cellular response to growth factor stimulus GO:0090287 13 0.046
stress activated mapk cascade GO:0051403 52 0.046
Human
male meiosis GO:0007140 52 0.046
regulation of dna metabolic process GO:0051052 34 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.046
cell projection assembly GO:0030031 94 0.045
cell cell junction assembly GO:0007043 38 0.045
response to external biotic stimulus GO:0043207 293 0.045
Human Mouse
regulation of gtpase activity GO:0043087 44 0.045
negative regulation of nervous system development GO:0051961 92 0.045
regulation of proteolysis GO:0030162 87 0.045
organonitrogen compound catabolic process GO:1901565 128 0.045
learning GO:0007612 75 0.045
actin filament based process GO:0030029 220 0.045
regulation of mitotic cell cycle GO:0007346 190 0.044
cellular amino acid metabolic process GO:0006520 61 0.043
positive regulation of gene expression GO:0010628 290 0.043
regulation of nervous system development GO:0051960 248 0.043
positive regulation of macromolecule metabolic process GO:0010604 405 0.043
meiosis i GO:0007127 59 0.043
cellular response to chemical stimulus GO:0070887 199 0.042
Human Mouse
maintenance of location GO:0051235 73 0.042
response to abiotic stimulus GO:0009628 341 0.042
axonogenesis GO:0007409 290 0.042
regulation of stem cell proliferation GO:0072091 40 0.042
regulation of locomotion GO:0040012 42 0.042
Human
nucleoside catabolic process GO:0009164 112 0.042
carbohydrate derivative catabolic process GO:1901136 118 0.041
regulation of phosphorylation GO:0042325 147 0.041
Human Mouse
defense response GO:0006952 300 0.041
mitotic cytokinesis GO:0000281 50 0.041
response to light stimulus GO:0009416 124 0.041
positive regulation of cell communication GO:0010647 250 0.041
response to endogenous stimulus GO:0009719 119 0.040
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
regulation of cellular amine metabolic process GO:0033238 3 0.039
extrinsic apoptotic signaling pathway GO:0097191 1 0.039
mitotic sister chromatid segregation GO:0000070 87 0.039
negative regulation of mitotic cell cycle GO:0045930 109 0.039
regulation of cell shape GO:0008360 113 0.038
cellular catabolic process GO:0044248 372 0.038
regulation of cell migration GO:0030334 22 0.038
Human
phagocytosis GO:0006909 215 0.038
cellular macromolecular complex assembly GO:0034622 153 0.037
regulation of gtp catabolic process GO:0033124 44 0.037
peptidyl tyrosine modification GO:0018212 24 0.037
single organism cellular localization GO:1902580 180 0.037
response to organic substance GO:0010033 284 0.037
Human Mouse
regulation of cell growth GO:0001558 43 0.037
ameboidal type cell migration GO:0001667 151 0.037
striated muscle cell differentiation GO:0051146 90 0.037
negative regulation of signal transduction GO:0009968 206 0.037
Human
regulation of cytoskeleton organization GO:0051493 89 0.036
regulation of cell proliferation GO:0042127 163 0.036
Human
positive regulation of cellular catabolic process GO:0031331 95 0.036
chemosensory behavior GO:0007635 106 0.035
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.035
hemopoiesis GO:0030097 46 0.035
regulation of kinase activity GO:0043549 53 0.035
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 85 0.035
regulation of cell cycle process GO:0010564 181 0.035
anterior posterior pattern specification GO:0009952 136 0.035
response to biotic stimulus GO:0009607 294 0.034
Human Mouse
negative regulation of gene expression GO:0010629 387 0.034
Human
negative regulation of biosynthetic process GO:0009890 277 0.034
Human Mouse
negative regulation of apoptotic process GO:0043066 63 0.034
sex differentiation GO:0007548 81 0.034
regulation of intracellular protein transport GO:0033157 46 0.034
regulation of cellular response to stress GO:0080135 89 0.034
regulation of protein localization GO:0032880 76 0.034
regulation of purine nucleotide metabolic process GO:1900542 62 0.033
oxoacid metabolic process GO:0043436 103 0.033
Mouse
gtp catabolic process GO:0006184 72 0.033
microtubule organizing center organization GO:0031023 168 0.033
regulation of anatomical structure size GO:0090066 163 0.033
mesenchymal cell differentiation GO:0048762 1 0.032
positive regulation of protein modification process GO:0031401 58 0.032
immune response activating signal transduction GO:0002757 2 0.032
developmental maturation GO:0021700 172 0.032
regulation of photoreceptor cell differentiation GO:0046532 34 0.031
regulation of cellular component movement GO:0051270 42 0.031
Human
positive regulation of cell motility GO:2000147 3 0.031
wnt signaling pathway GO:0016055 98 0.031
atp metabolic process GO:0046034 49 0.031
negative regulation of wnt signaling pathway GO:0030178 28 0.031
compound eye morphogenesis GO:0001745 249 0.031
epithelial cell proliferation GO:0050673 15 0.031
regulation of cell fate commitment GO:0010453 29 0.030
molting cycle GO:0042303 56 0.030
negative regulation of cell development GO:0010721 62 0.030
single organism biosynthetic process GO:0044711 206 0.030
Mouse
regulation of hydrolase activity GO:0051336 97 0.030
rhythmic process GO:0048511 106 0.029
germarium derived oocyte fate determination GO:0007294 26 0.029
gtp metabolic process GO:0046039 72 0.029
spermatid development GO:0007286 98 0.029
cellular response to organic substance GO:0071310 132 0.029
Human Mouse
purine nucleoside monophosphate metabolic process GO:0009126 50 0.029
regulation of mitosis GO:0007088 56 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
regulation of embryonic development GO:0045995 68 0.028
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.028
larval behavior GO:0030537 42 0.028
positive regulation of hydrolase activity GO:0051345 78 0.028
development of primary sexual characteristics GO:0045137 50 0.028
muscle cell differentiation GO:0042692 103 0.028
synapse assembly GO:0007416 143 0.028
dendrite development GO:0016358 204 0.028
cellular ketone metabolic process GO:0042180 24 0.028
Mouse
regulation of protein phosphorylation GO:0001932 64 0.027
Human Mouse
cellular response to external stimulus GO:0071496 66 0.027
response to alcohol GO:0097305 95 0.027
cellular response to nutrient levels GO:0031669 62 0.027
neuron projection guidance GO:0097485 241 0.027
positive regulation of growth GO:0045927 75 0.027
cellular protein localization GO:0034613 160 0.026
stem cell proliferation GO:0072089 88 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
axon development GO:0061564 297 0.026
negative regulation of immune system process GO:0002683 50 0.026
single organism catabolic process GO:0044712 228 0.026
regulation of protein transport GO:0051223 57 0.026
larval development GO:0002164 104 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.026
immune response regulating signaling pathway GO:0002764 2 0.025
eye photoreceptor cell development GO:0042462 81 0.025
response to extracellular stimulus GO:0009991 116 0.025
gastrulation GO:0007369 70 0.025
axon guidance GO:0007411 233 0.025
gland morphogenesis GO:0022612 145 0.024
appendage morphogenesis GO:0035107 397 0.024
negative regulation of cellular protein metabolic process GO:0032269 85 0.024
Human Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.024
signal release GO:0023061 49 0.024
ras protein signal transduction GO:0007265 88 0.024
cytokinesis GO:0000910 90 0.024
negative regulation of phosphate metabolic process GO:0045936 45 0.024
Human Mouse
olfactory behavior GO:0042048 97 0.024
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.024
positive regulation of cellular component biogenesis GO:0044089 80 0.024
protein modification by small protein conjugation or removal GO:0070647 106 0.023
renal tubule development GO:0061326 64 0.023
female meiotic division GO:0007143 70 0.023
organic acid metabolic process GO:0006082 103 0.023
Mouse
female meiosis chromosome segregation GO:0016321 33 0.023
mitotic nuclear division GO:0007067 213 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.023
regulation of response to dna damage stimulus GO:2001020 23 0.023
regulation of secretion by cell GO:1903530 39 0.023
regulation of epidermal cell differentiation GO:0045604 3 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
negative regulation of growth GO:0045926 84 0.022
wound healing GO:0042060 75 0.022
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.022
regulation of nucleoside metabolic process GO:0009118 50 0.022
forebrain development GO:0030900 2 0.022
regulation of immune system process GO:0002682 176 0.022
regulation of establishment of protein localization GO:0070201 61 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
regulation of nuclear division GO:0051783 58 0.022
digestive tract development GO:0048565 149 0.022
regulation of protein import into nucleus GO:0042306 28 0.022
stem cell maintenance GO:0019827 67 0.022
regulation of nucleotide metabolic process GO:0006140 62 0.021
fertilization GO:0009566 26 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
Human
regulation of imaginal disc derived wing size GO:0044719 20 0.021
response to hexose GO:0009746 3 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
guanosine containing compound catabolic process GO:1901069 74 0.020
nitrogen compound transport GO:0071705 85 0.020
cytoskeleton dependent cytokinesis GO:0061640 81 0.020
striated muscle cell development GO:0055002 50 0.020
response to oxygen containing compound GO:1901700 200 0.020
Human Mouse
establishment of tissue polarity GO:0007164 87 0.020
regulation of endocytosis GO:0030100 37 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
imaginal disc derived appendage development GO:0048737 399 0.020
chromatin organization GO:0006325 207 0.020
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
Mouse
circadian rhythm GO:0007623 105 0.020
intracellular protein transport GO:0006886 104 0.020
developmental programmed cell death GO:0010623 138 0.020
negative regulation of peptide hormone secretion GO:0090278 1 0.020
cellular protein complex assembly GO:0043623 71 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
nuclear import GO:0051170 51 0.019
gland development GO:0048732 191 0.019
phosphorylation GO:0016310 294 0.019
Human Mouse
cellular response to oxygen containing compound GO:1901701 79 0.019
Human Mouse
autophagic cell death GO:0048102 83 0.019
regulation of nucleocytoplasmic transport GO:0046822 35 0.019
connective tissue development GO:0061448 3 0.019
regulation of cell projection organization GO:0031344 92 0.019
positive regulation of cell proliferation GO:0008284 47 0.018
homeostatic process GO:0042592 199 0.018
microtubule bundle formation GO:0001578 27 0.018
salivary gland development GO:0007431 162 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.018
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.018
Human Mouse
cellular macromolecule localization GO:0070727 220 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
intrinsic apoptotic signaling pathway GO:0097193 16 0.018
Human
salivary gland morphogenesis GO:0007435 145 0.018
negative regulation of neuron death GO:1901215 18 0.018
epithelial cell migration GO:0010631 148 0.017
regulation of canonical wnt signaling pathway GO:0060828 15 0.017
positive regulation of histone deacetylation GO:0031065 2 0.017
attachment of spindle microtubules to kinetochore GO:0008608 5 0.017
olfactory learning GO:0008355 56 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
skin development GO:0043588 65 0.017
morphogenesis of follicular epithelium GO:0016333 36 0.017
regulation of stress activated mapk cascade GO:0032872 41 0.017
nucleoside monophosphate catabolic process GO:0009125 39 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
erbb signaling pathway GO:0038127 58 0.017
posttranscriptional gene silencing GO:0016441 46 0.017
mrna processing GO:0006397 104 0.017
cell maturation GO:0048469 144 0.017
regulation of programmed cell death GO:0043067 152 0.017
regulation of protein deacetylation GO:0090311 2 0.016
response to wounding GO:0009611 94 0.016
regionalization GO:0003002 416 0.016
response to organic cyclic compound GO:0014070 89 0.016
protein targeting to nucleus GO:0044744 51 0.016
protein transport GO:0015031 155 0.016
double strand break repair GO:0006302 26 0.016
negative regulation of organelle organization GO:0010639 56 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
Human Mouse
dna packaging GO:0006323 91 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
response to temperature stimulus GO:0009266 106 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
tube morphogenesis GO:0035239 191 0.016
stem cell division GO:0017145 69 0.016
motor neuron axon guidance GO:0008045 58 0.016
regulation of cell cycle phase transition GO:1901987 130 0.015
cell adhesion GO:0007155 136 0.015
oviposition GO:0018991 19 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
Human Mouse
negative regulation of catalytic activity GO:0043086 42 0.015
Human Mouse
chromatin modification GO:0016568 147 0.015
protein phosphorylation GO:0006468 169 0.015
Human Mouse
compound eye development GO:0048749 307 0.015
endosomal transport GO:0016197 44 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
protein localization to organelle GO:0033365 82 0.015
ribonucleoside monophosphate catabolic process GO:0009158 39 0.015
mesoderm development GO:0007498 78 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
adult behavior GO:0030534 137 0.015
regulation of cellular component size GO:0032535 98 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.015
positive regulation of protein deacetylation GO:0090312 2 0.015
epithelium migration GO:0090132 148 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.015
germarium derived egg chamber formation GO:0007293 101 0.015
maintenance of protein location in cell GO:0032507 26 0.014
regulation of apoptotic signaling pathway GO:2001233 10 0.014
outflow tract morphogenesis GO:0003151 4 0.014
mrna splicing via spliceosome GO:0000398 73 0.014
negative regulation of response to extracellular stimulus GO:0032105 6 0.014
centrosome cycle GO:0007098 137 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
regulation of proteasomal protein catabolic process GO:0061136 39 0.014
Mouse
regulation of protein complex assembly GO:0043254 42 0.014
regulation of cell junction assembly GO:1901888 2 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
tissue migration GO:0090130 155 0.014
anatomical structure homeostasis GO:0060249 97 0.014
phospholipid homeostasis GO:0055091 1 0.014
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.014
Mouse
response to nutrient levels GO:0031667 114 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
regulation of multicellular organismal development GO:2000026 414 0.014

trbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.035
disease of metabolism DOID:0014667 0 0.024
inherited metabolic disorder DOID:655 0 0.019